Antiparasitarios
Los antiparasitarios son compuestos diseñados para tratar y prevenir infecciones parasitarias mediante la inhibición del crecimiento y la supervivencia de los parásitos. Esta categoría incluye una variedad de agentes antiparasitarios destinados exclusivamente para uso en laboratorio y no para el consumo humano. Estos productos son esenciales para fines de investigación, permitiendo a los científicos estudiar los ciclos de vida de los parásitos, los mecanismos de acción y el desarrollo de resistencia. El uso de antiparasitarios en entornos de laboratorio ayuda en el descubrimiento y la optimización de nuevos tratamientos para enfermedades parasitarias, contribuyendo a los avances en parasitología médica y veterinaria. Los investigadores dependen de estos productos para mejorar su comprensión de las infecciones parasitarias y desarrollar terapias más efectivas.
Se han encontrado 704 productos de "Antiparasitarios"
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Diethyl Isobutylmalonate
CAS:Producto controlado<p>Applications Diethyl Isobutylmalonate is used as a reagent in the synthesis of quinoline-based zinc metallo-aminopeptidase inhibitors which have antimalarial activity.<br>References Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003)<br></p>Fórmula:C11H20O4Forma y color:NeatPeso molecular:216.275-Nitro-1H-quinolin-2-one
CAS:Producto controlado<p>Applications 5-Nitro-1H-quinolin-2-one is used in the synthetic preparation of novel antileishmanial agents for Leishmania donovani promastigotes.<br>References Paloque, L., et al.: Europ. J. Med. Chem., 54, 75 (2012);<br></p>Fórmula:C9H6N2O3Forma y color:NeatPeso molecular:190.163-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Producto controlado<p>Applications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs.<br>References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);<br></p>Fórmula:C10H12ClNO2Forma y color:NeatPeso molecular:213.6623-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS
CAS:Producto controladoFórmula:C42H66O8SiForma y color:NeatPeso molecular:727.054-(Aminomethyl)-cyclohexanone Hydrochloride
CAS:Producto controlado<p>Applications 4-(Aminomethyl)-cyclohexanone Hydrochloride is used to prepare dispiro-1,2,4-trioxolanes with antimalarial activities. It is also used to synthesize aminopyrimidines as SYK inhibitors useful in the treatment of SYK-mediated diseases.<br>References Tang, Y., et al.: Bioorg. Med. Chem. Lett., 17, 1260 (2007); Altman, M., et al.: PCT Int. Appl. (2011), WO 2011075515 A1 20110623<br></p>Fórmula:C7H13NO·HClForma y color:NeatPeso molecular:127.18 + 36.463-Aminopropionitrile (Stabilized with K2CO3)
CAS:Producto controladoFórmula:C3H6N2Forma y color:NeatPeso molecular:70.09Pseurotin A
CAS:Producto controlado<p>Applications Pseurotin A shows antiparasitic and anticancer activity. It exhibits inhibition towards IgE (immunoglobin E) production.<br>References Martinez-Luis, S. et al.: Nat. Prod. Comm., 7, 165 (2012); Bioorg. Med. Chem. Lett., 19, 1457 (2009);<br></p>Fórmula:C22H25NO8Forma y color:NeatPeso molecular:431.444-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one
CAS:Producto controlado<p>Applications 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one is a Kawain (K145490) derivative that is known to exhibit antimalarial and antituberculosis activities. 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one has been identified as a lead compound for the dual treatment of malaria and leishmaniasis.<br>References McCracken, S.T., et al.: Bioorg. Med. Chem., 20, 1482 (2012); Elzaawely, A.A.. et al.: Food. Chem., 103, 486 (2007); Xuan, T.D., et al.: J. Natural. Med., 62, 188 (2008);<br></p>Fórmula:C14H14O3Forma y color:NeatPeso molecular:230.262'-O-(2-Methoxyethyl)-5-methylcytidine (~90%)
CAS:Producto controladoFórmula:C13H21N3O6Pureza:~90%Forma y color:NeatPeso molecular:315.324,4'-Dimethyldiphenylamine
CAS:Producto controlado<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>Fórmula:C14H15NForma y color:NeatPeso molecular:197.282-Hydroxy-1-methyl-9,10-anthracenedione
CAS:Producto controladoFórmula:C15H10O3Forma y color:NeatPeso molecular:238.242,5-Diacetoxy-2,5-dihydrofuran (Mixture of Isomers) (>90%)
CAS:Producto controlado<p>Applications 2,5-Diacetoxy-2,5-dihydrofuran is used as a reagent to synthesize Mexicanin H, a biologically active sesquiterpene lactone that exhibits antiparasitic activity against Trypanosoma cruzi (a parasite that causes Chagas disease)<br>References Jimenez-Ortiz, V., et al.: Parasitology, 91, 170 (2005); Romo, J., et al.: Tetrahedron Lett., No vol. given, 1029 (1966)<br></p>Fórmula:C8H10O5Pureza:>90%Forma y color:NeatPeso molecular:186.16PBD-5,11-dione
CAS:Producto controlado<p>Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.<br></p>Fórmula:C12H12N2O2Forma y color:NeatPeso molecular:216.243-[(Dimethylamino)methyl]-2-hexanone
CAS:Producto controladoFórmula:C9H19NOForma y color:ColourlessPeso molecular:157.25Benzenebutanoic Acid Ethyl Ester
CAS:Producto controlado<p>Applications Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.<br>References Hamze, A. et al.: J. Med. Chem., 48, 3639 (2005); Ward, R. et al.: J. Med. Chem., 55, 3285 (2012);<br></p>Fórmula:C12H16O2Forma y color:NeatPeso molecular:192.25Tizoxanide - 98%
CAS:<p>Anti-parasitic; pyruvate ferredoxin oxidoreductase inhibitor</p>Fórmula:C10H7N3O4SPureza:Min. 95%Peso molecular:265.01573Oxfendazole
CAS:<p>Oxfendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating gastrointestinal parasites in livestock.</p>Fórmula:C15H13N3O3SPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:315.35 g/molAmoscanate
CAS:<p>Amoscanate is an antischistosomal agent, which is a synthetic compound with a broad spectrum of activity against parasitic infections. Its mode of action involves the disruption of parasite metabolism and structure, ultimately leading to the elimination of schistosomes. Schistosomes are trematode worms responsible for schistosomiasis, a significant parasitic disease affecting millions of people worldwide.</p>Fórmula:C13H9N3O2SPureza:Min. 95%Peso molecular:271.3 g/molIvermectin
CAS:<p>Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.</p>Fórmula:C48H74O14Pureza:85%MinPeso molecular:875.1 g/mol4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS:<p>4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.</p>Fórmula:C41H60O11Pureza:Min. 95%Peso molecular:728.91 g/molPF 1022A
CAS:<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>Fórmula:C52H76N4O12Pureza:Min. 95%Peso molecular:949.18 g/molHalofuginone
CAS:<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Fórmula:C16H17BrClN3O3Pureza:99.53%Forma y color:Off-White SolidPeso molecular:414.68Satranidazole
CAS:<p>Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.</p>Fórmula:C8H11N5O5SPureza:Min. 95%Peso molecular:289.27 g/molICA
CAS:<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Fórmula:C13H10N4SPureza:99.68%Forma y color:SolidPeso molecular:254.31Piperaquine
CAS:<p>Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.</p>Fórmula:C29H32Cl2N6Pureza:98%Forma y color:SolidPeso molecular:535.51BPH-715
CAS:<p>BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.</p>Fórmula:C17H31NO7P2Pureza:98.91%Forma y color:SolidPeso molecular:423.38Quinfamide
CAS:<p>Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.</p>Fórmula:C16H13Cl2NO4Pureza:99.92%Forma y color:SolidPeso molecular:354.18Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Fórmula:C16H17BrClN3O3·HBrPureza:97.01% - 99.73%Forma y color:SolidPeso molecular:495.59Antimalarial agent 26
CAS:<p>Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.</p>Fórmula:C20H22N4O3Pureza:98%Forma y color:SolidPeso molecular:366.41Antiparasitic agent-18
CAS:<p>Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.</p>Fórmula:C25H21N7OPureza:98%Forma y color:SolidPeso molecular:435.48Antimalarial agent 19
CAS:<p>Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.</p>Fórmula:C22H33Cl2N5SPureza:98%Forma y color:SolidPeso molecular:470.5Antimalarial agent 24
CAS:<p>Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM</p>Fórmula:C20H16N4O2Pureza:98%Forma y color:SolidPeso molecular:344.37Antimalarial agent 29
CAS:<p>Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.</p>Fórmula:C18H10ClF3N2Pureza:98%Forma y color:SolidPeso molecular:346.73Antileishmanial agent-14
CAS:<p>Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by</p>Fórmula:C23H26ClNO5Pureza:98%Forma y color:SolidPeso molecular:431.91Insecticidal agent 2
CAS:<p>Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].</p>Fórmula:C16H8ClF7N2O2Pureza:98%Forma y color:SolidPeso molecular:428.69Antileishmanial agent-15
CAS:<p>Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.</p>Fórmula:C28H39N5O4Pureza:98%Forma y color:SolidPeso molecular:509.64Epsiprantel
CAS:<p>Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.</p>Fórmula:C20H26N2O2Pureza:98.09%Forma y color:SolidPeso molecular:326.43CRK12-IN-2
CAS:<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Fórmula:C23H33F2N5O3S2Pureza:99.26% - 99.70%Forma y color:SolidPeso molecular:529.67Symetine
CAS:<p>Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.</p>Fórmula:C30H48N2O2Pureza:99.79%Forma y color:SolidPeso molecular:468.71(Rac)-ACT-451840
CAS:<p>(Rac)-ACT-451840 is an isomer of ACT-451840 exhibiting antimalarial activity against Plasmodium falciparum NF54.</p>Fórmula:C47H54N6O3Pureza:99.25%Forma y color:SolidPeso molecular:750.97Chalcone 4 hydrate
CAS:<p>Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.</p>Fórmula:C16H15ClO4Pureza:99.54%Forma y color:SolidPeso molecular:306.74Phosphodiesterase-IN-1
CAS:<p>Phosphodiesterase-IN-1 (Compound 7), a phosphodiesterase (PDE) inhibitor, exhibits anti-Plasmodium and antiproliferative activities. It effectively inhibits P. falciparum (strain 3D7) with an IC 50 value of 0.64 μM [1].</p>Fórmula:C15H15FN4OForma y color:SolidPeso molecular:286.3MMV006833
CAS:<p>MMV006833 is an inhibitor of Plasmodium falciparum. It targets the lipid transfer protein PfSTART1, inhibiting the ring-stage development of Plasmodium falciparum.</p>Fórmula:C19H27ClN2O4SForma y color:SolidPeso molecular:414.95Topoisomerase II inhibitor 16
CAS:<p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>Fórmula:C19H12F4N6OPureza:98%Forma y color:SolidPeso molecular:416.33SQ109
CAS:<p>SQ109 (NSC-722041) is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.</p>Fórmula:C22H38N2Pureza:99.70% - 99.91%Forma y color:SolidPeso molecular:330.55Antitrypanosomal agent 2
CAS:<p>Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.</p>Fórmula:C17H13N5O3Pureza:99.2%Forma y color:SolidPeso molecular:335.32Artelinic acid
CAS:<p>Artelinic acid is an artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.</p>Fórmula:C23H30O7Pureza:97.49% - 97.69%Forma y color:SolidPeso molecular:418.48Bithionol sulfoxide
CAS:<p>Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects against parasites, inhibiting Fasciola hepatica and Schistosoma mansoni.</p>Fórmula:C12H6Cl4O3SPureza:98.76%Forma y color:Off White To Tinch Pink Crystalline PowderPeso molecular:372.05Rufigallol
CAS:<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Fórmula:C14H8O8Pureza:98.92% - 99.27%Forma y color:SolidPeso molecular:304.21
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