Terpenoides

Agnuside is a diterpenoid compound, which is a phytoconstituent primarily sourced from the plant Vitex agnus-castus, commonly known as chaste tree. This compound is extracted from the fruit of the plant through a series of isolation and purification processes aimed at preserving its chemical integrity.

Cineole, often referred to as eucalyptol, is a monoterpenoid and a cyclic ether that represents a key constituent of certain essential oils. It is primarily sourced from the leaves of Eucalyptus species, but also found in smaller quantities within other aromatic plants such as rosemary, sage, and tea tree. Cineole exerts its effects through a multifaceted mode of action, acting predominantly as an antimicrobial and anti-inflammatory agent. This is achieved by disrupting the lipid membrane of microbial pathogens, leading to their destabilization and eventual demise. Additionally, cineole modulates inflammatory pathways by inhibiting the production of pro-inflammatory cytokines, thereby ameliorating symptoms associated with inflammation.

Isocalendin is a natural compound derived from the calendula plant, known for its potent anti-inflammatory properties. This product is extracted through a meticulous process that maintains the bioactive compounds inherent to calendula, ensuring efficacy and purity. Isocalendin functions by modulating inflammatory pathways at the cellular level, primarily inhibiting pro-inflammatory mediators. This selective action aids in reducing inflammation and promoting tissue repair without adverse effects associated with synthetic alternatives.

Inhibits canonical Wnt/β-catenin signaling; antineoplastic

Ginsenoside Rh3 is a bioactive saponin compound, which is a principle component isolated from Panax ginseng, a perennial plant widely known for its medicinal properties. This compound represents a specific form of ginsenoside with distinct pharmacological characteristics derived through the deglycosylation process of other ginsenosides during processing or digestion.

(1S)-(-)-(-)-Verbenone is a bicyclic monoterpene, which is a type of terpenoid compound. It is naturally sourced from various plants, predominantly from the essential oils of pines and other coniferous trees. The mode of action of Verbenone is intriguing; it acts as an anti-aggregation pheromone in certain beetle species, disrupting their communication and reducing infestation levels. This mechanism is particularly effective against bark beetles, which are known to cause significant damage to forestry ecosystems.

Toosendanin is a bioinsecticidal compound, which is a natural product isolated from the bark of the Melia toosendan tree, also known as the Chinese Melia. The source of this compound lies in the Meliaceae family, known for its diverse array of bioactive phytochemicals.

Valencene is a sesquiterpene, which is a naturally occurring terpenoid hydrocarbon. It is primarily sourced from the essential oils of citrus fruits, particularly Valencia oranges. Its mode of action involves its volatile nature, which contributes to its distinctive, sweet, citrusy aroma. Valencene is often synthesized or extracted using advanced biotechnological methods, ensuring high purity and consistency.

Triptophenolide methyl ether is a bioactive compound, classified as a terpene, derived from natural plant sources. It is primarily isolated from the roots of species within the *Tripterygium* genus. Terpenes are a large and varied class of organic compounds produced by a variety of plants, known for their aromatic qualities and biological activity.

Peppery aroma constituent of essential oil of Cyperus rotundus (nutgrass)

Prosaikogenin D is a type of saponin, which is a secondary metabolite derived primarily from the plant species within the Araliaceae family, notably ginseng and related plants. This compound is a result of bioconversion processes involving ginsenosides, which are the primary active components found in ginseng. The mode of action of Prosaikogenin D involves its interaction with various cellular pathways, leading to modulation of immune responses, anti-inflammatory effects, and potential anticancer activity.

Cinnamodial is a naturally occurring compound classified as a sesquiterpene dialdehyde, which is isolated from cinnamon oil, derived primarily from the bark of the Cinnamomum tree. Its primary mode of action involves disrupting cellular integrity through binding with fungal cell membranes, leading to increased permeability and ultimately cell death. This mechanism highlights its potential as an effective antifungal agent.

Danshenxinkun A is a herbal compound, which is derived from the root of Salvia miltiorrhiza, commonly known as Danshen. This product utilizes the bioactive constituents of the plant, primarily focusing on its polyphenolic compounds. The mode of action involves modulating various biological pathways, including antioxidant activity, vasodilation, and anti-inflammatory responses, which contribute to enhanced cardiovascular function.

20(R)Ginsenoside Rg2 is a bioactive compound, specifically a saponin, derived from Panax ginseng, a perennial plant in the Araliaceae family. This compound is one of the ginsenosides, which are the primary active constituents responsible for ginseng's pharmacological properties. Its mode of action involves modulation of cellular signaling pathways and neurotransmitter regulation, which contributes to its neuroprotective and cognitive enhancing effects.

Gypenoside Li is a phytochemical compound, which is derived from the plant Gynostemma pentaphyllum, commonly known as Jiaogulan. It functions primarily through modulating various biological pathways, including anti-inflammatory and antioxidant mechanisms, making it of significant interest for therapeutic research.

Tagitinin F is a sesquiterpene lactone, which is an organic compound derived from the aerial parts of the plant *Tithonia diversifolia*, commonly known as the Mexican sunflower. This plant-based compound functions through a mechanism that involves modulation of various cellular pathways, notably those related to inflammation and cancer progression, by interacting with cellular proteins and inhibiting key signaling molecules.

trans-Hydroxydavanone is a naturally occurring compound, which is a sesquiterpenoid ketone derived from the Artemisia species. It is characterized by its unique molecular structure that includes a hydroxyl group, contributing to its distinctive biochemical properties. The source of trans-Hydroxydavanone lies primarily in various species of the Artemisia plant, which are known for their diverse range of secondary metabolites.

Alpha-terpineol is a terpene alcohol that exhibits cytotoxic effects on cells. It has been shown to cause cell lysis in both bacteria and mammalian cells, which may be due to its reactive oxygen species (ROS) production. Alpha-terpineol is also an effective agent against infectious diseases such as HIV, tuberculosis, and malaria. This molecule has a high resistance to chemical degradation, making it a promising anticancer agent. Alpha-terpineol can inhibit the polymerase chain reaction (PCR) by binding to the enzyme DNA polymerase, thereby preventing the synthesis of DNA molecules. It can also bind to the enzyme RNA polymerase and inhibit the transcription of mRNA into protein molecules. Lastly, alpha-terpineol is known for its genotoxic effects in vivo and in vitro. The genotoxicity of alpha-terpineol has been demonstrated using several different methods including electron microscopy, chemical stability assays, surface methodology experiments on kidney bean extract,

Madecassic acid is a triterpenoid compound, which is a natural chemical constituent of Centella asiatica, commonly known as Gotu Kola. This source is a perennial herbaceous plant belonging to the Apiaceae family, widely distributed in tropical and subtropical countries. Madecassic acid acts primarily through its anti-inflammatory and antioxidant mechanisms. It modulates inflammatory responses by inhibiting the activation of NF-κB signaling pathways and reducing the production of pro-inflammatory cytokines. Additionally, it contributes to cellular protection by scavenging reactive oxygen species.

(-)-Secologanin is a monoterpenoid glycoside, which is a key intermediate in the biosynthesis of indole alkaloids, found primarily in plants such as those in the Apocynaceae and Rubiaceae families. It plays a crucial role in the natural production of complex alkaloids, forming the backbone for numerous pharmacologically active compounds, including quinine, camptothecin, and ajmalicine.