Cannabinoides
Los cannabinoides son una clase de compuestos químicos diversos derivados de ácidos grasos o poliquétidos que actúan sobre los receptores cannabinoides en las células, alterando la liberación de neurotransmisores en el cerebro. Se encuentran principalmente en las plantas de cannabis, y cannabinoides como el THC y el CBD son ampliamente estudiados por sus efectos terapéuticos, como el alivio del dolor, propiedades antiinflamatorias y su posible uso en enfermedades neurodegenerativas. En CymitQuimica, encontrará una amplia variedad de cannabinoides para investigaciones en farmacología, neurobiología y química médica.
Se han encontrado 372 productos para "Cannabinoides".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
GSK-554418A
CAS:GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.Fórmula:C19H19ClN4O2Forma y color:SolidPeso molecular:370.83Hemopressin(rat) TFA
CAS:Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.Fórmula:C55H78F3N13O14Forma y color:SolidPeso molecular:1202.28Tedalinab
CAS:Tedalinab is an effective and selective cannabinoid receptor 2 agonist.Fórmula:C19H21F2N3OPureza:98%Forma y color:SolidPeso molecular:345.39CB 65
CAS:CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.Fórmula:C22H28ClN3O3Pureza:99.53%Forma y color:SolidPeso molecular:417.93Prostaglandin E2-1-glyceryl ester
CAS:Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Fórmula:C23H38O7Forma y color:SolidPeso molecular:426.55PSB-SB1202
CAS:PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Fórmula:C23H26O4Forma y color:SolidPeso molecular:366.45CB2R-IN-1
CAS:CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).Fórmula:C23H27F3N4O6S3Pureza:98%Forma y color:SolidPeso molecular:608.67(R)-Monlunabant
CAS:(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].Fórmula:C26H22ClF3N6O3SPureza:98%Forma y color:SolidPeso molecular:591URB447
CAS:URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].Fórmula:C25H21ClN2OForma y color:SolidPeso molecular:400.9CB-52
CAS:CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].Fórmula:C26H43NO3Forma y color:SolidPeso molecular:417.62Isopropyl dodec-11-enylfluorophosphonate
CAS:Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibitsFórmula:C15H30FO2PPureza:98%Forma y color:SolidPeso molecular:292.37O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Fórmula:C23H36O3Forma y color:SolidPeso molecular:360.53O-2050
CAS:O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.Fórmula:C23H31NO4SPureza:98%Forma y color:SolidPeso molecular:417.56GW405833 hydrochloride
CAS:GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].Fórmula:C23H25Cl3N2O3Forma y color:SolidPeso molecular:483.822-Linoleoyl Glycerol
CAS:2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.Fórmula:C21H38O4Forma y color:SolidPeso molecular:354.531CB1 antagonist 1
CAS:CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, andFórmula:C26H22Cl2N4Pureza:98%Forma y color:SolidPeso molecular:461.39CB1 inverse agonist 1
CAS:MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.Fórmula:C25H18Cl3N3O3Pureza:99.92%Forma y color:SolidPeso molecular:514.79Ref: TM-T10694
1mg50,00€5mg105,00€1mL*10mM (DMSO)129,00€10mg155,00€25mg224,00€50mg314,00€100mg427,00€200mg577,00€Tricosanoyl Ethanolamide
CAS:Tricosanoyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, has an ethanolamine metabolite whose significance remains to be established.Fórmula:C25H51NO2Forma y color:SolidPeso molecular:397.688O-2545 hydrochloride
CAS:O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.Fórmula:C26H36N2O2HClForma y color:SolidPeso molecular:445SAD-448
CAS:SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.Fórmula:C24H28N4O8SForma y color:SolidPeso molecular:532.57
