Anticuerpos primarios

<p>RSV antibody was raised in mouse using fusion protein of RSV, types A and B as the immunogen.</p>

<p>SLIT2</p>

<p>VMP1</p>

<p>Rat Transferrin Reference Serum</p>

<p>Spectrin antibody was raised in rabbit using highly purified spectrin from human erythrocytes as the immunogen.</p>

<p>Cyclin D1 is a key regulator of cell proliferation and its expression and accumulation within cells is under tight control. Cyclin D1 is the regulatory subunit of cyclin-dependent kinases 4 and 6. These activated cyclin dependent kinases then phosphorylate the retinoblastoma protein (Rb) and drive G1 to S phase progression. Cyclin D1 promotes cell proliferation through interaction with transcription factors such as the oestrogen receptor and specificity protein 1 (Sp1). Cell proliferation is extremely sensitive to altered levels of cyclin D1, with even modest changes in its expression having noticeable effects on cell cycle progression.</p>

<p>SLIT genes encode the secreted ligands used for regulation of axon branching, pathfinding and neuronal migration. The secretory protein Slit homolog 2 (Slit2) and its transmembrane receptor protein Robo1 are evolutionarily conserved molecules thought to regulate axon guidance and neuronal cell migration._x000D_<br>Roundabout homologue 1 (Robo1) is the major Slit2 receptor, used to mediate the function of Slit homologue proteins needed for guiding major forebrain projections during neuronal development. Secreted Slit2 proteins mediate chemorepulsive signals on cells expressing robo1 receptors, allowing the normal growth and migrations of axons in the developing brain. Robo2 is also a receptor protein for the ligand Slit1, with these receptor-ligand interactions being necessary for proper ganglion formation._x000D_<br>Although primarily known for involvement in neuronal signalling, Slit/Robo signalling is involved in cell proliferation and cell mortality in a range of cell and tissue types.</p>

<p>Mouse monoclonal M13 + fd + F1 Filamentous Phages antibody (HRP)</p>

<p>CD28 antibody (Spectral Red) was raised in hamster using CD28 costimulatory receptor as the immunogen.</p>

<p>Anti-TRPA1 antibody</p>

<p>SLIT genes encode the secreted ligands used for regulation of axon branching, pathfinding and neuronal migration. The secretory protein Slit homolog 2 (Slit2) and its transmembrane receptor protein Robo1 are evolutionarily conserved molecules thought to regulate axon guidance and neuronal cell migration._x000D_<br>Roundabout homologue 1 (Robo1) is the major Slit2 receptor, used to mediate the function of Slit homologue proteins needed for guiding major forebrain projections during neuronal development. Secreted Slit2 proteins mediate chemorepulsive signals on cells expressing robo1 receptors, allowing the normal growth and migrations of axons in the developing brain. Robo2 is also a receptor protein for the ligand Slit1, with these receptor-ligand interactions being necessary for proper ganglion formation._x000D_<br>Although primarily known for involvement in neuronal signalling, Slit/Robo signalling is involved in cell proliferation and cell mortality in a range of cell and tissue types.</p>

<p>Please enquire for more information about anti-beta Galactosidase Antibody (Chicken) - Affinity Purified including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Goat polyclonal Human CRP antibody</p>

<p>Anti-huIgG antibody</p>

<p>Haptoglobin antibody was raised in goat using highly purified bovine haptoglobin as the immunogen.</p>

<p>LDHA antibody was raised in mouse using recombinant human LDHA (1-332aa) purified from E.coli as the immunogen.</p>

<p>CEP290 localises to the centrosomes of dividing cells and to the connecting cilium of photoreceptors. CEP290 associates with several microtubule-based transport proteins, including RPGR. CEP290 is located in the connecting cilium of cone and rod photoreceptors which is essential for the formation and stability of primary cilia regulating protein traffic between the photoreceptor inner and outer segments. As the maintenance of the outer segment of the photoreceptor relies on proteins and lipids trafficked from the inner segment, a reduction of functional CEP290 is believed to lead to retinal degeneration. Photoreceptor degradation can be due to a collapse of the connecting cilium and has been linked to CEP290. mutations in the gene encoding CEP290 can cause Leber congenital amaurosis (LCA), retinitis pigmentosa and early-onset severe retinal dystrophy. Aberrant CEP290 expression in other tissues is associated with Bardet-Biedl syndrome, Joubert syndrome, Meckel-Gruber syndrome, and Senior-LÞken syndrome. Biallelic loss-of-function mutations in CEP290 cause LCA-ciliopathy.</p>