Nucleótidos
Los nucleótidos son compuestos orgánicos que sirven como building blocks de los ácidos nucleicos, esenciales para la formación del ADN y ARN. Cada nucleótido está compuesto por una base nitrogenada, una molécula de azúcar y uno o más grupos fosfato. Estos nucleótidos se unen para formar largas cadenas, creando el material genético que lleva y transmite la información genética en todos los organismos vivos. En esta sección, encontrará una amplia variedad de nucleótidos cruciales para la investigación en genética, biología molecular y bioquímica. Son fundamentales para estudiar los procesos genéticos, sintetizar ácidos nucleicos y desarrollar herramientas diagnósticas y terapéuticas. En CymitQuimica, ofrecemos nucleótidos de alta calidad para apoyar su investigación científica y aplicaciones, asegurando precisión y fiabilidad en sus experimentos.
Subcategorías de "Nucleótidos"
Se han encontrado 2634 productos de "Nucleótidos"
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Guanosine5'-diphosphate
CAS:Pyruvate kinase substrateFórmula:C10H15N5O11P2Pureza:Min. 95%Forma y color:PowderPeso molecular:443.2 g/mol2'-Deoxyinosine-5'-triphosphate sodium,100mM aqueous solution
CAS:<p>2'-Deoxyinosine-5'-triphosphate sodium (2'-dITP) is a modified nucleotide that has antiviral and anticancer properties. It has been shown to be an activator for ribonucleosides, deoxyribonucleosides, and DNA. 2'-DITP has also been shown to inhibit the growth of human breast cancer cells in vitro.</p>Fórmula:C10H11N4Na4O13P3Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:580.09 g/molFludarabine phosphate
CAS:<p>Fludarabine phosphate is an antileukemic drug that inhibits DNA polymerase α and β, as well as other enzymes in the nucleotide synthesis pathway. It is used to treat patients with chronic myelogenous leukemia (CML) who have developed resistance to other treatments. Fludarabine phosphate has been shown to induce a cytotoxic effect against tumor cells by binding to ATP-binding cassette transporter proteins on the cell membrane and inhibiting intracellular targets such as DNA, RNA, and protein synthesis. Fludarabine phosphate has also been shown to inhibit the growth of tumor cells through synergistic interactions with other anticancer drugs such as hydroxyurea or busulfan, which may be due to its ability to inhibit enzyme activities such as erythrocyte alkaline phosphatase.</p>Fórmula:C10H13FN5O7PPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:365.21 g/mol3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:3'-Deoxyadenosine-5'-triphosphate sodium salt is a nucleotide that has been shown to be effective in chemotherapy. It is a substrate for the synthesis of DNA, RNA, and ATP. 3'-Deoxyadenosine-5'-triphosphate sodium salt is also a building block for DNA polymerase, which is an enzyme that synthesizes DNA from a template. It has been shown to have anticancer activity in drug-resistant cells and can be used as an alternative to purine analogs such as 6-mercaptopurine or cladribine. 3'-Deoxyadenosine-5'-triphosphate sodium salt has been shown to inhibit the production of nucleotides by blocking their conversion into triphosphates, which are necessary for DNA replication and repair. This inhibition leads to apoptosis in cells with high levels of nucleotide turnover such as cardiac and myeloid cells. The drug interactions may depend on theFórmula:C10H16N5O12P3Pureza:Min. 95%Forma y color:Colorless PowderPeso molecular:491.18 g/molN2-Benzoylguanosine
CAS:<p>N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.</p>Fórmula:C17H17N5O6Pureza:Min. 95%Forma y color:White to beige solid.Peso molecular:387.35 g/mol2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS:2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Fórmula:C21H38N2O6Si2Pureza:Min. 95%Peso molecular:470.72 g/mol3'-O-Propargyladenosine
CAS:3'-O-Propargyladenosine is a modified nucleoside that has antiviral and anti-inflammatory properties. It is a synthetic compound that is chemically related to adenosine. 3'-O-Propargyladenosine is an activator of the immune system and it inhibits viral DNA synthesis. The compound also has been shown to reduce inflammation in mice by inhibiting the production of prostaglandin E2 (PGE2). 3'-O-Propargyladenosine has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and cytomegalovirus (CMV).Fórmula:C13H15N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:305.29 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS:1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Fórmula:C9H13N2O9PPureza:Min. 95%Forma y color:PowderPeso molecular:324.18 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:Inhibitor of adenylyl and guanylyl cyclaseFórmula:C10H15N4O15P3·xC6H15NPureza:Min. 95%Forma y color:Colorless PowderPeso molecular:524.17 g/molUridine-3',5'-cyclic monophosphate sodium salt
CAS:<p>Uridine-3',5'-cyclic monophosphate sodium salt is a phosphotriester that is an intermediate in the biosynthesis of nucleosides. It is also a phosphodiesterase inhibitor, which means it inhibits the breakdown of cyclic nucleotides and allows them to accumulate. This drug has been shown to increase platelet production and has anti-inflammatory effects. Uridine-3',5'-cyclic monophosphate sodium salt is a human metabolite that can be synthesized from uridine, which is present in DNA, RNA, and food sources such as meat, eggs, and milk. The synthesis of uridine-3',5'-cyclic monophosphate sodium salt requires phosphoramidite as a precursor.</p>Fórmula:C9H10N2O8P·NaPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:328.2 g/mol2'-Deoxyuridine-5'-monophosphate disodium salt
CAS:<p>2'-Deoxyuridine-5'-monophosphate disodium salt (2DUMP) is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase. 2DUMP is a covalent inhibitor of thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. This compound has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2DUMP is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus. It has been shown to bind to benzalkonium chloride (BAK) in biological samples such as serum or plasma.<br>2DUMP binds to BAK through a covalent linkage between the 3' hydroxyl group on BAK and the phosphate group on 2DUMP</p>Fórmula:C9H11N2O8PNa2Pureza:Min. 95%Forma y color:PowderPeso molecular:352.15 g/mol2'-O-Propargyladenosine
CAS:<p>2'-O-Propargyladenosine is a modified nucleoside that belongs to the group of deoxyribonucleosides. It is an activator of viral DNA polymerases, which causes the synthesis of viral DNA to stop. This compound has antiviral and anticancer activities. 2'-O-Propargyladenosine has been shown to be effective against various human cancer cell lines in vitro and in vivo. It is a synthetic nucleoside with high purity, showing no detectable impurities by HPLC analysis.</p>Fórmula:C13H15N5O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:305.29 g/molAdenosine 3'-monophosphate sodium
CAS:Adenosine 3'-monophosphate sodium is a nucleotide that is used as a substrate for enzymes. It has been shown to increase the enzymatic activity of papaverine, litoralis, subtilis, and histidine phosphatase. Adenosine 3'-monophosphate sodium also has protease activity, which can be activated by adding an enzyme preparation containing subtilisin and trypsin. This compound also has a pH optimum of 8.0-9.5 and is active at an alkaline pH of 9.5-10.5. The specific strain of bacteria will determine the optimal pH range for activity, with enterobacter bacterial strains having a maximum range of 6-7 and brevibacterium bacteria strains having a range of 4-6.Fórmula:C10H12N5O7PNa2Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:391.19 g/mol2'-Deoxy-N2-methylguanosine
CAS:<p>2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.</p>Fórmula:C11H15N5O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:281.27 g/mol3'-Phosphoadenosine-5'-phosphosulfate lithium salt hydrate
CAS:Universal sulfonate donor for in vivo sulfonation by sulfotransferasesFórmula:C10H15N5O13P2S·xLi·yH2OPureza:Min. 60 Area-%Forma y color:White PowderPeso molecular:507.27 g/mol5-Bromo-2'-deoxycytidine
CAS:5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.Fórmula:C9H12BrN3O4Pureza:Min. 95%Forma y color:Off-White PowderPeso molecular:306.11 g/mol8-Aza-7-deaza-2'-deoxyguanosine
CAS:<p>8-Aza-7-deaza-2'-deoxyguanosine is an alkynylated, cross-linked, single stranded nucleic acid. It has been shown to be effective at cross-linking and cross-linking nucleic acids. 8-Aza-7-deaza-2'-deoxyguanosine binds to the 7 deazapurine residues in DNA, forming a covalent bond between the two strands of the helix. This binding prevents the strand from unwinding and prevents the replication of DNA. The thermodynamic data for this compound shows that it is stable in both hot and cold water, which makes it a good candidate for use in research as well as in clinical settings.</p>Fórmula:C10H13N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:267.24 g/mol2',3',5'-Tri-O-acetyl-8-bromoguanosine
CAS:<p>2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.</p>Fórmula:C16H18BrN5O8Pureza:Min. 95%Forma y color:Off-White To Light (Or Pale) Yellow SolidPeso molecular:488.25 g/mol7-Deaza-2',3'-dideoxy-7-iodoadenosine
CAS:7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.Fórmula:C11H13IN4O2Pureza:Min. 95%Forma y color:PowderPeso molecular:360.15 g/molN6-(6-Aminohexyl)-2'-deoxyadenosine
CAS:<p>N6-(6-Aminohexyl)-2'-deoxyadenosine is a novel nucleoside that is structurally related to the natural nucleosides, dATP and dGTP. It has been shown to be an activator of ribonucleosides and phosphoramidites, which are used in the synthesis of DNA and RNA. N6-(6-Aminohexyl)-2'-deoxyadenosine has also been shown to inhibit cancer cells as well as antiviral activity against HIV-1.</p>Fórmula:C16H26N6O3Pureza:Min. 95%Forma y color:Slightly Yellow PowderPeso molecular:350.43 g/mol
