Nucleótidos
Los nucleótidos son compuestos orgánicos que sirven como building blocks de los ácidos nucleicos, esenciales para la formación del ADN y ARN. Cada nucleótido está compuesto por una base nitrogenada, una molécula de azúcar y uno o más grupos fosfato. Estos nucleótidos se unen para formar largas cadenas, creando el material genético que lleva y transmite la información genética en todos los organismos vivos. En esta sección, encontrará una amplia variedad de nucleótidos cruciales para la investigación en genética, biología molecular y bioquímica. Son fundamentales para estudiar los procesos genéticos, sintetizar ácidos nucleicos y desarrollar herramientas diagnósticas y terapéuticas. En CymitQuimica, ofrecemos nucleótidos de alta calidad para apoyar su investigación científica y aplicaciones, asegurando precisión y fiabilidad en sus experimentos.
Subcategorías de "Nucleótidos"
Se han encontrado 2636 productos de "Nucleótidos"
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Caged GTP
CAS:Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.Fórmula:C18H23N6O16P3Pureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:672.33 g/mol5'-Deoxy-5'-iodoguanosine
CAS:5'-Deoxy-5'-iodoguanosine is a synthetic nucleoside that is used as a molecular probe to study the biochemical and physiological effects of UV irradiation. It has been shown to be reactive under in vitro conditions, and to have functionalities in vivo. 5'-Deoxy-5'-iodoguanosine has been used as a polymerase inhibitor, and it can also be used for the synthesis of oligonucleotides.Fórmula:C10H12IN5O4Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:393.14 g/mol2'-Deoxy-5'-O-DMT-N6-methyladenosine
CAS:2'-Deoxy-5'-O-DMT-N6-methyladenosine is a mutant of the natural nucleoside adenosine which has been synthesized as a model for the study of the enzyme ribonucleotide reductase. The mutant has a frameshift mutation, and the resulting protein is unable to catalyze DNA synthesis. It can be complemented by adding wild type nucleotides to regenerate the original sequence. 2'-Deoxy-5'-O-DMT-N6-methyladenosine inhibits the synthetase activity of ribonucleotide reductase and also inhibits polymerization of erythromycin B and styrene. 2'-Deoxy-5'-O-DMT-N6-methyladenosine has been shown to inhibit dehydrogenase activity in auxotrophs of Escherichia coli.Fórmula:C32H33N5O5Pureza:Min. 98 Area-%Forma y color:Off-White PowderPeso molecular:567.64 g/mol5-Chloro-5'-deoxyuridine
5-Chloro-5'-deoxyuridine is a nucleoside that is used as an antiviral agent and anticancer drug. It inhibits the viral DNA polymerase by acting as a phosphoramidite in the synthesis of viral DNA. 5-Chloro-5'-deoxyuridine is also used in the treatment of leukemia cells, which are resistant to other anticancer drugs. The high purity and modified nucleosides make this product highly desirable for research purposes. The novel syntheses of this product make it a desirable choice for many researchers.Fórmula:C9H11ClN2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:262.65 g/mol2'-Deoxy-N2-DMF-guanosine
CAS:2'-Deoxy-N2-DMF-guanosine is a synthetic nucleoside that is used as a primer in DNA sequencing and hybridization experiments. It binds to the 5' end of single-stranded DNA and is complementary to guanosine. The 2'-deoxy group on the sugar moiety prevents the formation of hydrogen bonds with other bases, which increases stability. In addition, it has a high affinity for dna binding proteins. This synthetic nucleoside has been shown to be useful in clinical diagnostics and can be used as a probe for detecting diazirine residues in DNA sequences.Fórmula:C13H18N6O4Pureza:Min. 97 Area-%Forma y color:White Off-White PowderPeso molecular:322.33 g/mol3'-Amino-2',3'-dideoxyguanosine
CAS:3'-Amino-2',3'-dideoxyguanosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.Fórmula:C10H14N6O3Pureza:(%) Min. 95%Forma y color:Off-White PowderPeso molecular:266.26 g/mol2-Thiouridine
CAS:2-Thiouridine is a uridine derivative that acts as a precursor for protein synthesis. It is synthesized from 2-amino-5-thiazole carboxylic acid and uracil in two steps, first with the formation of 2-thiouridine monophosphate and then with the conversion to 2-thiouridine diphosphate. The synthesis of 2-thiouridine is catalyzed by the enzyme uridine phosphorylase, which converts it to uridine monophosphate. 2-Thiouridine has been shown to have immunomodulatory effects in cell culture systems and animal models. These effects are believed to be due to its ability to act as an inhibitor of fatty acid synthase, which generates fatty acids from acetyl CoA. This process prevents the production of prostaglandins and leukotrienes, thereby reducing inflammation.Fórmula:C9H12N2O5SPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:260.27 g/molXanthosine 5'-monophosphate disodium salt
CAS:Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Fórmula:C10H11N4Na2O9PPureza:Min. 95%Forma y color:White Slightly Yellow PowderPeso molecular:408.17 g/mol2'-Deoxy-N3-methyluridine
CAS:2'-Deoxy-N3-methyluridine is a nucleoside analog that is used as a substrate in the synthesis of DNA. It can be incorporated into the DNA strand by enzymes called thymidylate synthases. 2'-Deoxy-N3-methyluridine has been shown to inhibit bacterial growth in cell cultures, and it is also active against marine sponges. The protonation state of the molecule determines its hydrophobicity and can be altered by adding a test compound to the solution. Hydrophobic molecules are more likely to bind with water molecules than hydrophilic molecules, which are more soluble in water.Fórmula:C10H14N2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:242.23 g/mol2',3'-Dideoxyuridine
CAS:Research tool for anti-viral and anti-cancer studies
Fórmula:C9H12N2O4Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:212.21 g/molN4,N4-Dimethylcytidine
CAS:N4,N4-Dimethylcytidine is a nucleoside that is an analog of cytidine. It has antiviral potency against influenza virus and inhibits the RNA-dependent DNA polymerase. N4,N4-Dimethylcytidine can be used to treat influenza and other viruses that are resistant to other antiviral drugs. This drug can be used in cell culture to inhibit the production of mismatched DNA strands, which is important for the replication of RNA viruses such as influenza. N4,N4-Dimethylcytidine also has been shown to be an inhibitor of miRNA activity in mammalian cells.
Fórmula:C11H17N3O5Pureza:(%) Min. 95%Forma y color:White PowderPeso molecular:271.27 g/molN4-Benzoyl-2'-O-methylcytidine
CAS:N4-Benzoyl-2'-O-methylcytidine is a triester of cytidine that is used in various biochemical research applications. It is enzymatically synthesized from cytidine and benzoyl chloride. N4-Benzoyl-2'-O-methylcytidine has been shown to have the same electrophoretic mobility as 5-hydroxyl cytidine, but it does not react with hydroxylamine to produce the corresponding hydroxylated product. This compound has also been used to study nucleic acid structure and function.
Fórmula:C17H19N3O6Pureza:Min. 95%Forma y color:PowderPeso molecular:361.35 g/molCoenzyme A hydrate
CAS:Coenzyme A hydrate is essential in the metabolism of fatty acids and the synthesis of acetyl-CoA. It is also employed in pharmaceutical applications, especially in drug development and formulation. Its distinctive properties improve drug solubility and bioavailability, making it an essential component in the creation of therapeutic agents.Fórmula:C21H36N7O16P3S·xH2OPureza:(Enzymatic) Min. 75%Forma y color:White Off-White Slightly Yellow PowderPeso molecular:767.54 g/mol2'-Deoxy-2-methoxyadenosine
CAS:2'-Deoxy-2-methoxyadenosine is a nucleoside that has been isolated from the sponge Spongospora. It is a glycosylated nucleoside that contains a formamidine chromophore and an amino function. The molecule has been synthesized by solid-phase synthesis, which involves the use of phosphoramidite chemistry to attach a series of building blocks onto an oligonucleotide template. 2'-Deoxy-2-methoxyadenosine was found to have thermal stability in phosphate buffer solutions and low reactivity with nucleophiles such as ammonia or methylamine. This nucleoside can be used as a substituent in synthetic organic chemistry and has been shown to inhibit the growth of bacteria such as Clostridium perfringens.Fórmula:C11H15N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:281.27 g/mol2'-Deoxypseudouridine
CAS:2'-Deoxypseudouridine is a nucleotide that is synthesized from the sugar ribose-5-phosphate and uracil. It is used in biological systems to transfer phosphate groups, which are vital to the metabolism of energy. 2'-Deoxypseudouridine also binds to DNA, forming stable complexes with enzymes and other molecules. This nucleotide is often found in oligodeoxynucleotides, which are used as antiviral agents. 2'-Deoxypseudouridine has been shown to have antimicrobial activity against various viruses, including hepatitis B virus (HBV). It has also been tested for its ability to inhibit replication of HIV-1 in vitro. The enzyme glycosylase catalyzes the reaction of 2'-deoxypseudouridine with water, producing an unstable intermediate that spontaneously converts into dUMP and pyrophosphate.Fórmula:C9H12N2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:228.21 g/mol5'-O-Benzoyl-2'-deoxyinosine
5'-O-Benzoyl-2'-deoxyinosine is an antiviral agent that inhibits the replication of certain viruses. It is a nucleoside analog that contains a benzoyl group at the 5' position and a 2'-deoxyribose sugar moiety. It has been shown to inhibit the growth of cancer cells in vitro and to produce cytotoxic effects on human lymphocytes. This compound is synthesized by reacting an appropriate ribonucleotide with phosphoramidite reagents, which are used as starting materials for DNA synthesis.Pureza:Min. 95%7-Cyano-7-deaza-2'-deoxyadenosine
CAS:7-Cyano-7-deaza-2'-deoxyadenosine is a nucleoside analog that inhibits the growth of virus by competing with deoxyadenosine for incorporation into DNA and RNA. 7-Cyano-7-deaza-2'-deoxyadenosine also stabilizes dna duplexes and prevents them from breaking down. It has been shown to be effective against herpes simplex virus, which causes painful blisters on the skin or genitals. This drug has been used in clinical trials as an antiviral agent. 7-Cyano-7-deaza-2'-deoxyadenosine is synthesized from 2',3'-didehydrocytidine under the following conditions:
Fórmula:C12H13N5O3Pureza:Min. 95%Forma y color:PowderPeso molecular:275.26 g/molUridine-5-oxyacetic acid
CAS:Uridine-5-oxyacetic acid is a molecule that is synthesized from uridine and 5-oxo-4-pyrone. It is an intermediate in the synthesis of pyrimidine nucleotides, which are important for DNA replication, repair, and transcription. Uridine-5-oxyacetic acid has been shown to form stable complexes with subtilisin. These complexes have been determined by X-ray crystallography to be glycosidic bond between the uridine and the enzyme. The enzymatic activity of subtilisin can be inhibited by these complexes, which may lead to frameshifting during bacterial translation. This inhibition leads to a less efficient protein synthesis process and a decrease in the production of gene products.
Fórmula:C11H14N2O9Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:318.24 g/molMalonyl coenzyme A lithium salt - 97%
CAS:Malonyl-CoA is a metabolite that regulates the storage of fat and the production of energy in adipose tissue. Malonyl coenzyme A lithium salt is a fatty acid, which has been shown to reduce insulin resistance in response to diet in mice. It also has an anti-obesity effect by lowering body weight and reducing fat mass accumulation. The mechanism for this is not fully understood but may involve regulation of tnf-α activity and adipocyte hypertrophy.Fórmula:C24H37N7O19P3S·xLiPureza:Min. 95%Forma y color:PowderPeso molecular:852.57 g/mol2',3'-Dideoxyguanosine
CAS:2',3'-Dideoxyguanosine is a nucleoside for use in research applicationsFórmula:C10H13N5O3Pureza:Min. 95%Forma y color:PowderPeso molecular:251.25 g/mol
