
Nucleósidos
Se han encontrado 3569 productos de "Nucleósidos"
2'-Deoxycytidine-5'-carboxylic acid
CAS:2'-Deoxycytidine-5'-carboxylic acid (2'-DC) is a modified nucleoside that has been used as an anticancer, antiviral, and synthetic agent. 2'-DC inhibits the synthesis of DNA by binding to the enzyme DNA polymerase. It also inhibits viral replication by inhibiting the activity of reverse transcriptase and can be used as a potential anti-HIV drug. In addition, 2'-DC has been shown to have cytotoxic effects against cancer cells in vitro. This compound is synthesized from cytidine 5-monophosphate and phosphoramidite reagents in high purity and quantity. The CAS number for this compound is 4603-72-9.
Fórmula:C9H11N3O5Pureza:Min. 95%Peso molecular:241.2 g/mol6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one
CAS:6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is a novel nucleoside analog that has been modified to contain an antiviral agent. It is phosphorylated at the 2' position to form a monophosphate. This compound is a potent inhibitor of HIV reverse transcriptase and human DNA polymerases α and β. The structure of this compound contains a furano ring fused with the pyrimidine moiety, which is substituted with methyl groups on C6 and C3 positions. The CAS number for 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is 383897−60−7.Fórmula:C12H14N2O5Pureza:Min. 95%Peso molecular:266.25 g/molRef: 3D-IQA89760
Producto descatalogado2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt
2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) is a synthetic nucleoside that acts as an antiviral, anticancer and antineoplastic agent. It has been shown to inhibit the replication of DNA and RNA by inhibiting the activity of ribonucleoides. 2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) can be used in combination with other antiviral agents such as acyclovir or valacyclovir to treat herpes simplex virus type 1 infections. The drug is also effective against HIV, with a potency similar to that of zidovudine. It has been shown to be active in the treatment of leukemia, lymphoma, Hodgkin's disease and some solid tumors.Pureza:Min. 95%3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt
Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C13H22N3O14P3•(C6H15N)xPureza:Min. 99 Area-%Forma y color:PowderPeso molecular:537.25 g/mol2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å
2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.
Pureza:Min. 95%N6-Benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å
N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is a novel nucleoside with antiviral activity. It is synthesized by the condensation of 2'-deoxyadenosine monophosphate and 3'-Q linker CPG 1000 Å. The molecular weight of N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is 878.36 g/mol, and its CAS number is 628674-06-4. This substance has antiviral activity against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). N6-benzoyl-2'-deoxy-5'-O-DMT adenosine can be used as an anticancer drug because it inhibits the growth
Pureza:Min. 95%Ref: 3D-NB11617
Producto descatalogado3'-epi-5-chloro-2'-deoxyuridine
CAS:3'-epi-5-chloro-2'-deoxyuridine is a nucleotide analog that has been shown to inhibit the growth of cells in tissue culture. It is not active against bacteria, but can be used as an antineoplastic agent for the treatment of cancer. 3'-epi-5-chloro-2'-deoxyuridine is metabolized by a number of enzymes, including mononucleotide reductase, thymidylate synthase, and cytosine deaminase. The reaction mechanism for this drug has been studied using nuclear dna polymerases and proteases. The metabolism of 3'-epi-5-chloro-2'-deoxyuridine results in its incorporation into DNA by means of an enzymatic reaction with DNA polymerase. The incorporation of the analog into DNA leads to cell death due to lysis or inhibition of protein synthesis.
Fórmula:C9H11ClN2O5Pureza:Min. 95%Peso molecular:262.65 g/molRef: 3D-NE16712
Producto descatalogado2-Hydroxyaminoadenosine
CAS:2-Hydroxyaminoadenosine (2-HAA) is a novel nucleoside that is used as an activator of ribonucleotide reductase. It has been shown to be effective against cancer cells in vitro and in vivo. 2-HAA also inhibits the synthesis of viral DNA, which may be due to its ability to inhibit the ribonuclease activity of the virus. 2-HAA has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1).
Fórmula:C10H14N6O5Pureza:Min. 95%Peso molecular:298.26 g/molDdCTP trilithium
CAS:2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon
Fórmula:C9H13N3Li3O12P3Pureza:Min. 95%Forma y color:LiquidPeso molecular:468.96 g/molRef: 3D-ND10280
Producto descatalogadoNicotinic acid-13C6 riboside
CAS:Please enquire for more information about Nicotinic acid-13C6 riboside including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C6C5H13NO6Pureza:Min. 95%Peso molecular:260.17 g/molN4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine
N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.
Fórmula:C21H23N3O7Pureza:Min. 95%Peso molecular:429.43 g/mol5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid
CAS:5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is a pyrimidine derivative that inhibits protein kinases. The compound has been shown to inhibit the activity of protein kinase C, which is involved in mediating inflammatory responses, and phosphorylation of the insulin receptor substrate 1. 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is an efficient inhibitor of kinases and can be used as a lead compound for the development of new compounds with therapeutic potential.Fórmula:C6H5BrN2O2SPureza:Min. 95%Peso molecular:249.09 g/molRef: 3D-NB44268
Producto descatalogado5'-O-DMT-2'-O-(2-methoxyethyl)uridine
CAS:5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.
Fórmula:C33H36N2O9Pureza:Min. 95%Peso molecular:604.65 g/mol2',3'-Dideoxycytidine 5'-monophosphate
CAS:Dideoxycytidine 5'-monophosphate (DDCMP) is a molecule that inhibits HIV infection by inhibiting the synthesis of DNA. It binds to the dna template strand, preventing the addition of new nucleotides and thus blocking the progression of HIV infection. DDCMP has been shown to be potent in vitro and in vivo in clinical studies. In cell culture, DDCMP has been shown to inhibit DNA duplexes, leading to a decrease in lymphocytic leukemia cells activated by T-cell receptor stimulation. Structural biology studies have revealed that DDCMP inhibits HIV-1 reverse transcriptase through binding at the M2 subunit of the enzyme's active site.
Fórmula:C9H14N3O6PPureza:Min. 95%Forma y color:PowderPeso molecular:291.2 g/molRef: 3D-ND170662
Producto descatalogado3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt
Producto controlado3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt is a novel antiviral nucleoside phosphoramidite that has been shown to be an effective activator in the synthesis of diphosphate and triphosphate analogs. The novel antiviral nucleoside phosphoramidite was synthesized from 3'-azido-3'-deoxythymidine, methyl bromoacetate and sodium hydroxide in methanol at room temperature. It is structurally similar to the natural nucleosides, deoxyribonucleosides and ribonucleosides with modifications on the sugar moiety and phosphate group. This compound is a high quality synthetic material for use in pharmaceutical research, as an anticancer agent and as a potential antiviral drug.Fórmula:C16H17D3N5NaO10Pureza:Min. 95%Forma y color:PowderPeso molecular:468.36 g/molRef: 3D-NA04586
Producto descatalogado5-Azauridine
CAS:5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.
Fórmula:C8H11N3O6Pureza:Min. 95%Forma y color:PowderPeso molecular:245.19 g/mol2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt
2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt is an activator that has been synthesized for therapeutic use. It is a modified nucleoside, which means that it does not occur naturally in the human body and must be made artificially. This drug is currently undergoing clinical trials and is being studied for its anticancer properties. 2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt binds to the phosphate groups on DNA and inhibits viral replication by preventing RNA synthesis. It also has antiviral activity against Herpes simplex virus type 1, HIV type 1, and influenza A virus type H1N1. The drug may have potential as a treatment for chronic hepatitis B infection as well as various cancers such as breast cancer, prostate cancer, and leukemia.
Pureza:Min. 95%8-Oxo-N2-isobutyryl-2-deoxyguanosine
CAS:8-Oxo-N2-isobutyryl-2-deoxyguanosine is a modified synthetic nucleoside. It finds applications in understanding mutagenesis and DNA repair mechanisms.
Fórmula:C14H19N5O6Pureza:Min. 95%Peso molecular:353.33 g/molRef: 3D-LFA85976
Producto descatalogadoN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG is a nucleotide analog with antiviral and anticancer activity. It is considered to be a novel nucleoside analogue. It is synthesized by attaching an acetyl group to the 2' position of the adenosine moiety, which prevents phosphorylation by kinase enzymes. This inhibits DNA synthesis and induces apoptosis in cancer cells.
Pureza:Min. 95%Forma y color:PowderRef: 3D-ND57353
Producto descatalogadoN4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine
N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine is an antiviral drug that inhibits viral DNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. It is a nucleoside analog that is used for the treatment of cancer and for the prevention of AIDS. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5 -iodocytidine is synthesized in high purity, with a purity level of > 98%. This product can be used as an activator or ligand in phosphoramidite synthesis.Fórmula:C22H30IN3O5SiPureza:Min. 95%Forma y color:PowderPeso molecular:571.48 g/molRef: 3D-NB09206
Producto descatalogado3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine
3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a novel nucleoside analogue with anticancer activity. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a modified deoxyribonucleoside monophosphate, which is activated by phosphorylation to the corresponding diphosphate form and then converted to an antiviral agent. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This compound also inhibits the proliferation of human cancer cells in vitro and in vivo.
Fórmula:C33H34N2O9Pureza:Min. 95%Peso molecular:602.63 g/mol3',5'-O-(Di-tert-butylsilanediyl)uridine
CAS:3',5'-O-(Di-tert-butylsilanediyl)uridine is a novel antiviral agent that is synthesized from uridine and has been shown to be effective against herpes simplex virus. This compound was also shown in vitro to inhibit the replication of human immunodeficiency virus type 1 (HIV-1). 3',5'-O-(Di-tert-butylsilanediyl)uridine binds to single stranded DNA, preventing the synthesis of DNA by the viral enzyme reverse transcriptase. It also inhibits the production of viral proteins by binding to viral RNA polymerase. This drug may also have anticancer activity due to its ability to inhibit ribonucleotide reductase, an enzyme required for DNA synthesis.
Pureza:Min. 95%5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium, 100mM aqueous solution
5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.
Fórmula:C12H17N4O13P3•Li4Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:545.97 g/molRef: 3D-NA32075
Producto descatalogado2',3'-Dideoxy-2',2'-difluorocytidine
CAS:2',3'-Dideoxy-2',2'-difluorocytidine is a monophosphate derivative of the antiviral and anticancer drug 2',3'-dideoxycytidine. It is an activator of DNA synthesis, nucleosides, and nucleotides. It is also a phosphoramidite for the synthesis of oligonucleotides and modified ribonucleosides. 2',3'-Dideoxy-2',2'-difluorocytidine has CAS number 124708-94-7. It is available in high purity and quality, which makes this product suitable for research purposes.
Pureza:Min. 95%Ref: 3D-ND158370
Producto descatalogadoUridylyl-3'-5'-cytidine ammonium salt
Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.
Fórmula:C18H27N6O13PPureza:Min. 95%Peso molecular:566.41 g/molEthyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS:Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.
Fórmula:C8H8F3N3O2Pureza:Min. 95%Peso molecular:235.16 g/mol2'-TFA-NH-dG
CAS:2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.
Fórmula:C12H13F3N6O5Pureza:Min. 95%Peso molecular:378.26 g/mol2'-Deoxy-N2-isobutyrylcytidine
CAS:2'-Deoxy-N2-isobutyrylcytidine is a nucleoside analogue of cytidine that has been modified with a 2-amino-2-deoxyribose moiety. The transaminated product is more stable than the parent compound and has improved anticoagulant activity. It has also been shown to be active in inhibiting DNA synthesis and cell proliferation in vitro. 2'-Deoxy-N2-isobutyrylcytidine inhibits the growth of bacteria by binding to their ribosomes, preventing protein synthesis. This compound has also been shown to inhibit the formation of blood clots in mice.
Fórmula:C13H19N3O5Pureza:Min. 95%Peso molecular:297.31 g/molRef: 3D-ND02994
Producto descatalogadoN6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine
6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine (BBD) is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and also a novel monophosphate nucleotide. BBD has been shown to inhibit the replication of RNA in cells infected with HIV and HSV.
Pureza:Min. 95%E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine
CAS:E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine is a monophosphate nucleoside analog that has been modified to be resistant to antiviral ribonucleases. This drug is phosphorylated in vivo to the corresponding diphosphate and triphosphate, which inhibits viral DNA synthesis and thus prevents the virus from replicating. E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine can be used as an antiviral agent against herpes simplex virus (HSV).Fórmula:C34H34N2O9Pureza:Min. 95%Peso molecular:614.66 g/molRef: 3D-NC08240
Producto descatalogadoLinoleoyl coenzyme A
CAS:Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.
Fórmula:C39H66N7O17P3SPureza:Min. 95%Peso molecular:1,029.97 g/mol3'-Deoxy-3',4'-didehydro-CTP
CAS:3'-Deoxy-3',4'-didehydro-CTP is a nucleoside analog. It is a novel, high quality, high purity and synthetic compound with antiviral and anticancer activities. 3'-Deoxy-3',4'-didehydro-CTP inhibits the synthesis of DNA by specifically inhibiting the activity of DNA polymerase. The IC50 value for this compound is 12.5 μM against herpes simplex virus type 1 (HSV-1) in vitro.
Fórmula:C9H14N3O13P3Pureza:Min. 95%Peso molecular:465.14 g/molRef: 3D-FD180918
Producto descatalogadoCytidine 5'-monophosphate sodium salt
CAS:Cytidine 5'-monophosphate sodium salt is a nucleotide that is found in RNA and DNA. Cytidine 5'-monophosphate sodium salt is an intermediate in the biosynthesis of uridine, choline, and saccharose. It also plays an important role in the immune system as it can be a precursor for immunoglobulins. The reaction rate of cytidine 5'-monophosphate sodium salt with lipase has been shown to be constant at pH 7.5-8.0 and 37°C. This product has been shown to have emulsifying properties by forming micelles with water-immiscible solvents such as hexane or heptane, which may be due to its ability to form hydrogen bonds with other molecules such as saccharose or guanosine. Cytidine 5'-monophosphate sodium salt can also be used as a chromatographic material for separating saccharose from other sugars
Fórmula:C9H14N3O8P·xNaPureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:323.2 g/mol2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation into
Fórmula:C10H12N5O11P3·4LiPureza:Min. 95%Forma y color:PowderPeso molecular:498.91 g/molRef: 3D-ND32077
Producto descatalogadoN6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS:N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.
Fórmula:C24H23N5O5Pureza:Min. 95%Peso molecular:461.5 g/molRef: 3D-SFA97940
Producto descatalogado2'-Deoxy-N6-phenoxyacetyladenosine
CAS:2'-Deoxy-N6-phenoxyacetyladenosine is a cyclic oligonucleotide analog that has been shown to be efficient in inhibiting the replication of RNA. It binds to the RNA polymerase, preventing transcription and replication of the nucleic acid. 2'-Deoxy-N6-phenoxyacetyladenosine is also an effective inhibitor of DNA synthesis and can inhibit the synthesis of proteins by binding to ribosomes. This drug is structurally similar to deoxyadenosine, which is a component of DNA, and it has been shown to be more potent than other analogs.
Fórmula:C18H19N5O5Pureza:Min. 97 Area-%Peso molecular:385.38 g/mol5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite
CAS:5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.Fórmula:C41H49N4O9PPureza:Min. 95%Peso molecular:772.82 g/mol5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole
CAS:5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as anFórmula:C18H18Cl2N2O7Pureza:Min. 95%Peso molecular:445.25 g/molRef: 3D-ND16534
Producto descatalogado3',5'-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-o-methyluridine
CAS:3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a novel monophosphate nucleoside analog that is activated by T4 polynucleotide kinase. It is synthesized from the corresponding phosphoramidite and reacts with the 5'-OH group of a ribonucleoside to form a 3',5'-di-O-acetylribonucleoside. The diacetyl group confers increased stability to the molecule and also provides an acetyl group for incorporation into DNA. This compound has antiviral activity against herpes simplex virus type 1 (HSV1) in cell culture and has shown anticancer properties in animal studies.
Fórmula:C23H27FN2O8Pureza:Min. 95%Peso molecular:478.5 g/molRef: 3D-UJB35532
Producto descatalogado3',5'-Di-O-acetyl-2'-deoxyguanosine
CAS:3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.
Fórmula:C14H17N5O6Pureza:Min. 95%Forma y color:PowderPeso molecular:351.32 g/molRef: 3D-ND04500
Producto descatalogadoNonadecanoyl coenzyme A
CAS:Nonadecanoyl coenzyme A is a fatty acid that is produced by the bovine liver and has been shown to have anabolic effects. Nonadecanoyl CoA is involved in the synthesis of various lipids, such as phospholipids, cholesterol, and glycolipids. It also plays a role in biosynthesis of fatty acids and in regulating ATP production. Nonadecanoyl CoA is synthesized from acetate by the enzyme acetyl-CoA carboxylase (ACC). ACC catalyzes the conversion of acetyl-CoA to malonyl-CoA, which can then be used for fatty acid synthesis. Nonadecanoyl CoA has been found to play an important role in regulating mitochondrial function through its ability to activate long-chain acyl-CoAs desaturase (LCAD). LCAD converts long-chain acyl-CoAs into their corresponding dicarboxylic acids.
Fórmula:C40H72N7O17P3SPureza:Min. 95%Peso molecular:1,048.02 g/mol2-Methylthio-6-chloropurine
CAS:2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.
Fórmula:C6H5CIN4SPureza:Min. 95%Peso molecular:304.11 g/mol3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
CAS:3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.
Fórmula:C22H39N5O6Si2Pureza:Min. 95%Peso molecular:525.75 g/molRef: 3D-NT16564
Producto descatalogado3'-O-Methyl-5'-guanylic acid
CAS:3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.
Fórmula:C11H16N5O8PPureza:Min. 95%Peso molecular:377.25 g/mol2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine (dAraMP) is a novel nucleoside analogue that was synthesized and characterized. It has been shown to inhibit the growth of cancer cells in vitro. dAraMP is a monophosphate analogue of 2,6-diamino-9-(2'-deoxy-b-D-ribofuranosyl)purine (dAraP). The modified phosphoramidite approach used in its synthesis yielded high purity and yields. This product is also available as a diphosphate analogue of 2,6 diamino 9-(2'-amino 2'-deoxy b D ribofuranosyl) purine (dAMP). The diphosphate form of this product has been shown to be an activator for DNA polymerase.Fórmula:C10H15N7O3Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:281.28 g/molRef: 3D-ND06322
Producto descatalogado4-Aminopyrimidine-5-carboxylic acid
CAS:4-Aminopyrimidine-5-carboxylic acid is an aminopyrimidone that has been synthesized to be used as a new class of antihypertensive agents. It has dose-dependent blood pressure lowering effects, which are likely due to its ability to block angiotensin receptors. 4-Aminopyrimidine-5-carboxylic acid also has antibacterial and antifungal properties. This compound is metabolized in vivo into the pharmacologically active amine 6-aminonicotinamide and excreted in the urine. In vitro studies have shown that 4-aminopyrimidine-5 carboxylic acid inhibits the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes required for cell division.
Fórmula:C5H5N3O2Pureza:Min. 95%Peso molecular:139.11 g/molRef: 3D-NA57368
Producto descatalogado3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine
3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine is a novel 3'-amino nucleoside
Fórmula:C37H36N4O6Pureza:Min. 95%Peso molecular:632.71 g/molRef: 3D-NA08780
Producto descatalogado3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine
3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.
Fórmula:C32H31FN2O8Pureza:Min. 95%Peso molecular:590.6 g/molRef: 3D-NA08460
Producto descatalogado5-Methyl-2',3'-stannyluridine
5-Methyl-2',3'-stannyluridine is a nucleoside analog that is a potent inhibitor of viral replication and can be used for the treatment of HIV. It has been shown to inhibit the activity of RNA polymerase, thereby preventing transcription and replication. 5-Methyl-2',3'-stannyluridine also inhibits DNA synthesis by inhibiting the activity of DNA polymerase. This drug also acts as an antitumor agent and has been shown to inhibit tumor growth in animal models. The high purity of this drug makes it suitable for use in pharmaceutical applications.
5-Methyl-2',3'-stannyluridine is a modified nucleoside that has been modified with a stannyl group at the 2' position on the sugar moiety and an allyl group at the 3' position on the sugar moiety. The phosphoramidites are synthesized from 5-methyl-2',3'-stannylPureza:Min. 95%3'-O-tert-Butyldimethylsilyladenosine
CAS:3'-O-tert-Butyldimethylsilyladenosine is a synthetic nucleoside that is an antiviral agent with high purity. It has been shown to have anticancer properties and can be used as a deoxyribonucleoside activator or as a novel monophosphate nucleoside. 3'-O-tert-Butyldimethylsilyladenosine is also modified with an alkyl group for the phosphoramidite building block synthesis of DNA, RNA, and oligonucleotides. It has been shown to inhibit the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase in cells.Pureza:Min. 95%2'-O-Hexylaminoguanosine
2'-O-Hexylaminoguanosine is a modified nucleoside that has antiviral properties. It is an activator of the human immune system and is used to treat cancer. 2'-O-Hexylaminoguanosine inhibits the synthesis of DNA by phosphoramidite addition to the monophosphate form of guanosine, which prevents RNA synthesis and therefore also protein synthesis. It also has anticancer effects by inhibiting the growth of cells in culture.
Pureza:Min. 95%3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine
CAS:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.
Fórmula:C23H17Cl2FN2O7Pureza:Min. 95%Peso molecular:523.29 g/molRef: 3D-ND22464
Producto descatalogado2'-Deoxy-5'-O-DMT-adenosine
CAS:2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.
Fórmula:C31H31N5O5Pureza:Min. 95%Forma y color:PowderPeso molecular:553.61 g/molRef: 3D-ND57357
Producto descatalogado7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS:7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.
Fórmula:C14H14ClN3Pureza:Min. 95%Peso molecular:259.73 g/mol1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole
CAS:1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole is a nucleoside that can be used as an activator for phosphoramidite synthesis. It is also known to have antiviral, anticancer, and antimalarial properties. 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole has been shown to inhibit the proliferation of human leukemia cells in culture. It has also been shown to suppress HIV replication in vitro by inhibiting viral RNA synthesis.Fórmula:C14H17NO3Pureza:Min. 95%Peso molecular:247.3 g/molRef: 3D-ND06396
Producto descatalogadoDMTr-TNA-C(Bz)-amidite
CAS:Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C45H50N5O8PPeso molecular:819.9 g/molN2-Benzoylguanosine
CAS:N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.
Fórmula:C17H17N5O6Pureza:Min. 95%Forma y color:White to beige solid.Peso molecular:387.35 g/molRef: 3D-NB06331
Producto descatalogado5'-O-Tosylthymidine
CAS:5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Fórmula:C17H20N2O7SPureza:Min. 95%Peso molecular:396.42 g/molRef: 3D-NT10016
Producto descatalogado3′-Guanylic acid disodium
CAS:3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.
Fórmula:C10H14N5O8P•Na2Pureza:Min. 95%Peso molecular:409.2 g/molRef: 3D-NG182606
Producto descatalogado5′-O-DMT-LNA N-Bz adenosine
CAS:5′-O-DMT-LNA N-Bz adenosine is a novel nucleoside that has been modified with an aminooxy group. The compound is synthesized by the phosphoramidite method and it is designed for use in antiviral and anticancer research. 5′-O-DMT-LNA N-Bz adenosine can be used as a substrate for DNA polymerases and other enzymes to produce nucleic acid strands. This product is CAS No. 206055-74-5, monophosphate, Phosphoramidites, Synthetic, Deoxyribonucleosides, Anticancer, Ribonuclesides, High purity.
Fórmula:C39H35N5O7Pureza:Min. 95%Peso molecular:685.73 g/molRef: 3D-ND182842
Producto descatalogadoRibavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.
Fórmula:C8H15N4O14P3•(C6H15N)xPureza:Min. 95 Area-%Forma y color:Clear LiquidPeso molecular:789.732'-Deoxy-4'-ethynyl-2-fluoroadenosine
CAS:2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long
Fórmula:C12H12FN5O3Pureza:Min. 95%Peso molecular:293.25 g/mol5-Methyl-L-uridine
CAS:5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.
Fórmula:C10H14N2O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:258.23 g/mol2',3',5'-Tri-O-acetylinosine
CAS:2′,3′,5′-Tri-O-acetylinosine is a protected form of the nucleoside inosine, with potential for use in the preparation of modified nucleotides and nucleoside analogs.
Fórmula:C16H18N4O8Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:394.34 g/molRef: 3D-NT06708
Producto descatalogado2-Chloroadenosine 5'-monophosphate triethylamine salt
CAS:2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.
Fórmula:C10H13ClN5O7P·C12H30N2Pureza:Min. 95%Peso molecular:584.05 g/molRef: 3D-NC10383
Producto descatalogado2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate
CAS:10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position
Pureza:Min. 95%2',3'-Dideoxy-3',5-difluorocytidine
CAS:2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.
Pureza:Min. 95%dNaM
CAS:dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.
Fórmula:C16H18O4Pureza:Min. 95%Peso molecular:274.31 g/molArchaeosine
CAS:Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.
Fórmula:C12H16N6O5Pureza:Min. 95%Peso molecular:324.29 g/mol
