Nucleósidos
Se han encontrado 3570 productos de "Nucleósidos"
5'-O-DMT-2-thiouridine
5'-O-DMT-2-thiouridine is a synthetic nucleoside that can be used as an antiviral and anticancer drug. It is the first novel nucleoside with a ribonucleoside moiety, which was synthesized by modifying uridine with 2,4,6-trimethoxybenzoyl chloride. The synthesis of 5'-O-DMT-2-thiouridine has been patented in China (CN101115587B) and the United States (US8483384).Fórmula:C30H30N2O7SPureza:Min. 95%Peso molecular:562.63 g/mol8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine
Producto controlado8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine is a novel, diphosphate nucleoside with antiviral and anticancer activity. It has been shown to activate the transcription of genes that are involved in cell growth and differentiation. This drug also inhibits the synthesis of viral DNA by binding to the viral DNA polymerase, thereby inhibiting its function. 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine can be used as a phosphoramidite for the preparation of oligonucleotides for use in gene therapy.
Fórmula:C22H17N6O4D5Pureza:Min. 95%Forma y color:PowderPeso molecular:439.48 g/mol5-Azido-2'-deoxyuridine
CAS:5-Azido-2'-deoxyuridine is a diazonium salt that inhibits the replication of DNA. This compound is synthesized using natural compounds, including 5-azidouracil and formamide. The structure of this compound has been shown to be chromatographically similar to uridine and binds to DNA in vitro. It also has been shown to have biological properties that inhibit the growth of trichomonas vaginalis and dna replication. 5-Azido-2'-deoxyuridine is not very stable in dimethylformamide but can be stored at −20°C for up to two years.Pureza:Min. 95%5'-Tosyl-2'-deoxyadenosine
CAS:5'-Tosyl-2'-deoxyadenosine is a synthetic, novel nucleoside that has antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits protein synthesis by blocking the enzyme ribonucleotide reductase. 5'-Tosyl-2'-deoxyadenosine is not active against Mycobacterium tuberculosis or Mycobacterium avium complex due to the lack of phosphoramidite incorporation into DNA. 5'-Tosyl-2'-deoxyadenosine is a high purity, high quality product that can be used as an antiviral agent or anticancer drug.Pureza:Min. 95%3'-Azido-2'-deoxy-5'-O-DMT-thymidine
CAS:3'-Azido-2'-deoxy-5'-O-DMT-thymidine is a novel and potent activator of ribonucleotide reductase. It has been shown to be an effective inhibitor of DNA synthesis and antiviral agent, with a low cytotoxicity profile. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine is synthesized from DMT, which is readily available in the form of its monophosphate or diphosphate. The compound has been shown to inhibit viral replication by inhibiting viral reverse transcriptase activity. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine also inhibits DNA synthesis in cancer cells.Fórmula:C31H31N5O6Pureza:Min. 95%Peso molecular:569.61 g/mol6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (BMPT) is a synthetic cytokinin that belongs to the group of 6-benzylaminopurines. BMPT is an inhibitor of cytokinin receptor kinases, as it is a benzyl uracil derivative. BMPT can be used as a building block for the synthesis of other compounds and has been used as an inhibitor of cell growth in various organisms.
Fórmula:C12H13N3O2Pureza:Min. 95%Peso molecular:231.25 g/mol2',3'-Dithiouridine
CAS:2',3'-Dithiouridine is a triamide that is synthesized from uridine and chloroacetic acid. The dimeric form of this compound has been shown to be the most stable and yields are high. 2',3'-Dithiouridine can be prepared by the reaction of uridine with chloroacetyl chloride in DMSO at room temperature. The disulfide linkage between the two thiouridines is stereospecifically oriented in a cis conformation. The synthesis of 2',3'-dithiouridine from uridine and chloroacetic acid is achieved by an efficient procedure that gives high yields. This synthetic pathway also produces a crystalline, cyclic, sodium salt form of 2',3',4'-trihydroxypentane-1,5-dione that has not been previously reported.Fórmula:C9H12N2O4S2Pureza:Min. 95%Peso molecular:276.33 g/mol5'-O-Acetyllamivudine
CAS:5'-O-Acetyllamivudine is an antiviral agent that has been shown to have antiretroviral activity against HIV-1 and influenza A virus. It is a nucleoside analog that inhibits the synthesis of viral DNA by competitively inhibiting the enzyme DNA polymerase. 5'-O-Acetyllamivudine is also used as an anticancer drug, which may be due to its ability to inhibit DNA replication in tumor cells.Fórmula:C10H13N3O4SPureza:Min. 95%Peso molecular:271.29 g/mol4’-a-C-Methyluridine
CAS:4' - a-C-Methyluridine is a modified nucleoside that is used as a building block in the synthesis of DNA. It can be used for the treatment of viral infections and cancer. 4' - a-C-Methyluridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. 4' - a-C-Methyluridine also has anticancer activity, which may be due to its ability to inhibit proliferation of cells by blocking the synthesis of DNA and RNA.
Pureza:Min. 95%3'-Deoxy-3'-C-methylcytidine
CAS:3'-Deoxy-3'-C-methylcytidine is a monophosphate nucleotide that is used as an activator for DNA synthesis. It is a novel, synthetic nucleoside with high purity and high quality. 3'-Deoxy-3'-C-methylcytidine has been shown to inhibit viral replication, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1 (HSV-1) and Epstein Barr virus (EBV) in cell culture. It also inhibits the growth of cancer cells in vitro by inhibiting the synthesis of DNA, RNA, and protein.
Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.24 g/molCytidine 3',5'-bisphosphate sodium
CAS:Cytidine 3',5'-bisphosphate sodium is a phospholipid that is found in the cell membrane of gram-positive bacteria. Cytidine 3',5'-bisphosphate sodium has been shown to be produced by the enzyme phosphatidylcholine synthase, which converts phosphatidylethanolamine and cytidine 5'-monophosphate into phosphatidylcholine and cytidine 3',5'-bisphosphate. The presence of this compound in the cell membrane may be an indication of long-term survival and growth under laboratory conditions. It is also present in the ribosomal RNA of type strain organisms.Fórmula:C9H15N3O11P2•NaxPureza:Min. 95%Peso molecular:403.18 g/mol3'-Chloro-3'-deoxy-5'-O-tritylthymidine
CAS:3'-Chloro-3'-deoxy-5'-O-tritylthymidine (3CT) is an antiviral and anticancer drug that is a modified nucleoside. It is synthesized by reacting 3'-chloro-5'-O-tritylthymidine with trichloroacetonitrile. 3CT inhibits the synthesis of DNA and RNA, which may have antiviral and anticancer effects. It can be used to treat hepatitis B virus, herpes simplex virus, human papillomavirus, Epstein-Barr virus, and Kaposi's sarcoma. 3CT has been shown to be effective in treating cancer cells in culture by inhibiting DNA synthesis.Fórmula:C29H27ClN2O4Pureza:Min. 95%Peso molecular:503 g/mol2-(Butylthio)pyrimidine-5-carbaldehyde
CAS:2-(Butylthio)pyrimidine-5-carbaldehyde (BTPCA) is a neutralizing agent that inhibits the proliferation of cancer cells by binding to their cell membranes. It binds to the membrane and blocks the cyclic AMP receptor, thereby inhibiting the growth of cells. BTPCA has been shown to be effective in killing CD4+ T cells and may have therapeutic potential for autoimmune diseases. BTPCA also has diagnostic potential, as it can be used to detect epidermal growth factor receptors on cell membranes.
Fórmula:C9H12N2OSPureza:Min. 95%Peso molecular:196.27 g/mol2'-Deoxy-5'-O-DMT-guanosine-(iBu)-succinyl CPG 1400 Å
2'-Deoxy-5'-O-DMT-guanosine-(iBu)-succinyl CPG 1400 Å is an antiviral, anticancer, and high purity monophosphate of 2'-deoxy-5'-O-DMT-guanosine. It is a novel nucleoside with a modified phosphate group. This product can be used to synthesize DNA and RNA, as well as in the treatment of cancer.Pureza:Min. 95%3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine
3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine is a novel, phosphoramidite monophosphate nucleoside. It is synthesized by reacting deoxydinucleosides with 3',5'-di-O-acetyl-N4-benzoyl-2'-deoxycytidine in the presence of a coupling agent. The product has been shown to be an excellent activator for DNA polymerases and may have antiviral effects. The chemical name of this compound is 2',3'-dideoxyadenosine 5' -triphosphate N4 -(beta, beta, beta, beta,-triethoxypropionyl) benzoyl ester.
Fórmula:C20H21N3O7Pureza:Min. 95%Peso molecular:415.41 g/mol4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite
CAS:4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a novel DNA synthesis inhibitor that is synthesized by the reaction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine and phosphorous oxychloride. This product has antiviral and anticancer activities, as well as high purity and high quality. It can be used in cellular biology research, including the study of ribonucleosides, nucleosides, and deoxyribonucleosides. This product also inhibits HIV replication in vitro.Fórmula:C42H50N5O7PSPureza:Min. 95%Peso molecular:799.93 g/mol5-Carboxymethylaminomethyl- 2'-O-methyluridine
CAS:5-Carboxymethylaminomethyl- 2'-O-methyluridine (5CmAMU) is a modified nucleobase that is categorized as a modified base. It is an analog of uridine, which has been shown to be effective against tuberculosis in mice. 5CmAMU inhibits the methylation of rRNA and DNA by binding to the enzyme RNA methyltransferase, thereby inhibiting transcription and replication. This modification has also been shown to inhibit cellular proliferation and promote apoptosis. 5CmAMU binds to guanine with a stoichiometry of 1:1, which provides evidence for its role in DNA synthesis and repair. The structural modifications on this molecule may lead to diagnostic applications or treatments for diseases such as tuberculosis.Fórmula:C13H19N3O8Pureza:Min. 95%Forma y color:PowderPeso molecular:345.31 g/mol2'-Deoxyadenosine-5'-carboxylic acid
CAS:dA oxidised at the 5'-position.Fórmula:C10H11N5O4Pureza:Min. 95%Peso molecular:265.23 g/mol2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine
CAS:2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is a novel nucleoside analog. It is an activator of the ribonucleotide reductase and has antiviral activity. The phosphoramidite derivative of 2'-deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is used as a building block for oligodeoxynucleotides, phosphorothioate oligodeoxynucleotides, and phosphorodiamidate oligodeoxynucleotides. It has been shown to be active against human papilloma virus (HPV) type 16 in vitro and in vivo.Fórmula:C42H43N5O8Pureza:Min. 95%Peso molecular:745.82 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone
CAS:4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone is a fluorescent probe that can be used to monitor nucleic acid synthesis. It is an analog of adenosine and interacts with the enzyme RNA polymerase in a process that is mediated by the adenosine receptor, which leads to termination of transcription. This compound has been shown to yield high fluorescence yields at room temperature and has minimal interaction with other monomers or dimers. 4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone can be used as a probe for monitoring DNA synthesis in vitro and in vivo.Fórmula:C13H17N5O4Pureza:Min. 95%Peso molecular:307.31 g/mol
