Nucleósidos
Se han encontrado 3569 productos de "Nucleósidos"
3’-Deoxy- 3'- methylguanosine
CAS:3’-Deoxy-3'-methylguanosine is a nucleoside that is used in the synthesis of DNA. 3’-Deoxy-3'-methylguanosine is a monophosphate that can be obtained from the phosphoramidites, which are intermediates in the chemical synthesis of nucleotides. 3’-Deoxy-3'-methylguanosine is an activator for DNA polymerases and has been shown to have antiviral, anticancer, and antifungal properties. It has also been shown to be cytotoxic against leukemia cells. 3’-Deoxy-3'-methylguanosine is a novel nucleoside with modified properties.Fórmula:C11H15N5O4Pureza:Min. 95%Peso molecular:281.27 g/mol2',3',5-Tri-O-acetyl-2-chloroadenosine
CAS:2',3',5-Tri-O-acetyl-2-chloroadenosine is a modified nucleoside that has been shown to be a potent activator of the transcriptional activator protein 2 (AP2) and AP1. The ribonucleosides are synthesized by phosphoramidite chemistry and are prepared as monophosphate or diphosphate derivatives. 2',3',5-Tri-O-acetyl-2-chloroadenosine also has antiviral activity against herpes simplex virus type 1 (HSV1). This drug is highly purified and can be used in high quality applications, such as anticancer and antiviral treatments.
Fórmula:C16H18ClN5O7Pureza:Min. 95%Peso molecular:427.8 g/mol5'-O-Levulinoylthymidine 3'-CE phosphoramidite
CAS:5'-O-Levulinoylthymidine 3'-CE phosphoramidite is a novel, high quality diphosphate nucleoside. It is modified with levulinic acid and has antiviral and anticancer properties. 5'-O-Levulinoylthymidine 3'-CE phosphoramidite is synthesized from 5'-O-levulinoylthymidine monophosphate, which is synthesized from thymidine and levulinic acid. The synthesis of 5'-O-levulinoylthymidine 3'-CE phosphoramidite starts with the reaction of 1 equivalent of thymidine with 1 equivalent of levulinic acid in aqueous solution at pH 7 to 8 at 100°C for 2 hours, followed by purification by HPLC.Fórmula:C24H37N4O8PPureza:Min. 95%Peso molecular:540.55 g/molLNA-guanosine 3'-CE phosphoramidite
CAS:LNA-guanosine 3'-CE phosphoramidite is a novel, high purity, activated nucleoside. It is an anti-cancer and antiviral agent that is synthetically modified to include a phosphate group at the 3' position of the sugar moiety. This modification prevents viral inhibition by inhibiting viral DNA synthesis. LNA-guanosine 3'-CE phosphoramidite is also used as an anticancer agent due to its ability to inhibit ribonucleotide reductase and diphosphate reductase, which are enzymes required for DNA synthesis.Pureza:Min. 95%N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine
N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.Pureza:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine
N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that is used as an antiviral, anticancer, and antiretroviral agent. It is a potent inhibitor of HIV replication in vitro and in vivo. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine inhibits the activity of viral reverse transcriptase and DNA polymerase by binding to their RNA template strand. The drug shows efficacy against leukemia cells in vitro and against murine leukemia L1210 cells in vivo. Treatment with N4-acetyl-2'-deoxy-5'-O-DMT cytidine has been shown to reduce the size of tumors in mice with fibrosarcoma, melanoma, or glioma xenografts. N4 acetyl 2’ deoxy 5’ O DMT cytidine is alsoFórmula:C33H35N3O7Pureza:Min. 95%Peso molecular:585.65 g/mol3’-O-(2-Methoxyethyl)adenosine
CAS:3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.Fórmula:C13H19N5O5Pureza:Min. 95%Peso molecular:325.32 g/molThymidine-5'-diphosphate-6-deoxy-D-allose
Thymidine-5'-diphosphate-6-deoxy-D-allose (TDP) is a high quality monophosphorylated nucleoside that is used as an activator, anticancer, and antiviral agent. TDP has been modified to improve the efficacy and safety of cancer treatments by enhancing the cytotoxicity of chemotherapeutics. TDP also has antiviral properties and can be used in the treatment of HIV infections by inhibiting viral replication.
Pureza:Min. 95%(+)-Emtricitabine
CAS:Emtricitabine is a synthetic nucleoside analog of cytidine. It is used in the treatment of HIV infection and hepatitis B virus infection. Emtricitabine binds to human DNA polymerase, preventing the incorporation of viral DNA into the host cell's genome. This prevents the virus from multiplying and reproducing, thereby inhibiting the spread of HIV in humans. The drug has been shown to inhibit replication at all stages of HIV-1, including reverse transcription and integration into host cell DNA. Emtricitabine also inhibits replication of other viruses such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV). Emtricitabine is a prodrug that must be activated by phosphorylation before it can be incorporated into DNA. This activation requires tenofovir alafenamide hemifumarate as an activator, which is an experimental drug with improved bioavailability, reduced renal clearance, andFórmula:C8H10FN3O3SPureza:Min. 95%Peso molecular:247.25 g/molL-Inosine
CAS:L-Inosine is a purine nucleoside that is found in plants and animals. It is an intermediate in the pentose phosphate pathway and can be synthesized from the amino acid L-lysine. L-Inosine has been shown to inhibit the growth of trichomonas vaginalis and giardia, but not uninfected human erythrocytes. The mechanism of action of L-Inosine is not well understood, but it may have a role in transporting adenosine into cells. The oral bioavailability of L-Inosine is low due to its rapid conversion to l-adenosine by nonsaturable enzymes. L-Inosine does not appear to be a substrate for transport across mammalian cells, but it does act as a competitive inhibitor for glucose transport.Fórmula:C10H12N4O5Pureza:Min. 95%Forma y color:Off-White SolidPeso molecular:268.23 g/mol1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine
1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is a synthetic nucleoside that acts as an activator of DNA synthesis and inhibits viral replication. It is used in the treatment of cancer and antiviral therapy. 1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is also used as a building block for the modification of other nucleosides, including deoxyribonucleosides, ribonucleosides, and nucleotides. The drug is available in high purity at a low cost.
Fórmula:C10H13ClN2O5Pureza:Min. 95%Peso molecular:276.67 g/molFluorescein-dt cep
CAS:Fluorescein-dt cep is a monophosphate nucleoside analog that is modified with an activated ester group. It is used as a prodrug for the treatment of influenza in humans. Fluorescein-dt cep has antiviral activity, which may be due to its ability to inhibit viral RNA synthesis. This agent also has anticancer activity and has been shown to kill leukemia cells by interfering with DNA synthesis. The chemical name for fluorescein-dt cep is 1-(2,6-dichloro-4-(5,7-dimethoxy-4-methylpyridiniumyl)phenyl)cytosine monophosphate. Fluorescein-dt cep is also known by the following synonyms: 1-(2,6-Dichloro-4-(5,7-dimethoxyquinoliniumyl)phenyl)-1H-[1,3]dioxFórmula:C79H89N6O17PPureza:Min. 95%Peso molecular:1,425.6 g/mol2-Iodo-2',3'-O-isopropylideneadenosine
CAS:2-Iodo-2',3'-O-isopropylideneadenosine is a phosphoramidite nucleoside that is used for the synthesis of oligonucleotide DNA. It has antiviral and anticancer properties, as well as a novel chemical structure. 2-Iodo-2',3'-O-isopropylideneadenosine has been synthesized in high purity and quality. It is also available in CAS No. 141018-25-9.Fórmula:C13H16IN5O4Pureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:433.21 g/molBenzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside
CAS:Benzyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranoside is a synthetic nucleoside analog. It is an antiviral agent that inhibits the activity of reverse transcriptase and DNA polymerase. Benzyl 2-acetamido-2-deoxy--3,4,6--tri--O--acetyl--β--D--glucopyranoside has been shown to be active against hepatitis B virus and herpes simplex virus type 1. It also has been shown to inhibit the production of HIV in cell culture and is being investigated as a potential anti AIDS drug.Pureza:Min. 95%TFA-ap-dU
CAS:TFA-ap-dU is a modified, ribonucleosides that are used in DNA synthesis. The polymerase chain reaction (PCR) technique can be used to generate a large number of copies of a specific sequence of nucleotides from the original DNA template. This product is used for antiviral and anticancer research. TFA-ap-dU has been shown to be effective against Hepatitis B virus and Human Immunodeficiency Virus (HIV). It is also an activator of DNA and RNA synthesis.
Fórmula:C14H14F3N3O6Pureza:Min. 95%Peso molecular:377.27 g/mol2-Chloro-3-deazaadenosine
CAS:2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.
Fórmula:C11H13ClN4O4Pureza:Min. 95%Forma y color:PowderPeso molecular:300.7 g/mol2-Methylaminoadenosine
CAS:2-Methylaminoadenosine is a nucleoside that is the product of the action of adenosine deaminase on 2-aminoadenosine. It is used in diagnostic assays to differentiate between n6-methyladenosine and deoxyadenosine in DNA, RNA, or serum samples. It has been shown to have an interaction with fatty acids and their derivatives and sequences in tissues. In addition, it has been shown to have specificities for cardiac tissue and a flow rate that is constant.Fórmula:C11H16N6O4Pureza:Min. 95%Peso molecular:296.28 g/molCarbodine
CAS:Carbocyclic analog of cytidineFórmula:C10H15N3O4Pureza:Min. 95%Forma y color:PowderPeso molecular:241.24 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine
2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine is a novel antiviral drug that has been shown to be active against influenza, herpes, and HIV. It belongs to the class of deoxyribonucleosides and is ribonucleotide analogs. 2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine inhibits viral replication by interacting with viral DNA polymerase, preventing the extension of viral DNA chains by blocking the incorporation of nucleotides into the growing strand. The enzyme activity of 2'-deoxy-N2-isobutyrylguanosine is activated by phosphoramidites in vitro.
Fórmula:C19H25N5O7Pureza:Min. 95%Peso molecular:435.43 g/mol6-Benzylamino-9-(a-D-glucopyranosyl)purine
CAS:6-Benzylamino-9-(a-D-glucopyranosyl)purine is a novel nucleoside phosphoramidite that has been synthesized as an intermediate for anticancer therapy. It is a monophosphate, which has antiviral and antifungal activity. 6-Benzylamino-9-(a-D-glucopyranosyl)purine is a synthetic nucleoside with a novel structure, which inhibits the synthesis of DNA and RNA. This drug also has ribonucleotide reductase inhibitory activities.Fórmula:C18H21N5O5Pureza:Min. 95%Peso molecular:387.4 g/mol
