Nucleósidos
Se han encontrado 3569 productos de "Nucleósidos"
2',3'-Dideoxy-3'-fluoroadenosine
CAS:2',3'-Dideoxy-3'-fluoroadenosine (ddFdA) is an antiviral drug that has been shown to be effective against HIV and other viruses. It is a synthetic nucleoside analogue of the natural purine adenosine. ddFdA inhibits the synthesis of viral RNA and DNA by competitively inhibiting the enzyme ribonucleotide reductase, thereby blocking DNA synthesis. The drug has shown significant activity in humans with immunodeficiency, but also has toxic effects on lymphocytes. ddFdA is synthesised from 2',3'-dideoxyadenosine (ddAdo), which is produced by the action of adenosinase on adenosine. In humans, ddFdA is converted to dideoxyadenosine triphosphate (ddATP), which inhibits cellular proliferation.Fórmula:C10H12FN5O2Pureza:Min. 95%Peso molecular:253.23 g/mol2'-O-(2-Ethoxy-2-oxoethyl)adenosine
2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a nucleoside that is a modified version of adenosine. It is phosphorylated to form 2'-O-(2-ethoxy-2-oxoethyl)adenosin-5'-yl monophosphate, which has antiviral activity and is used as an antiviral agent in the treatment of herpes simplex virus. The chemical structure of this nucleoside is novel, and it binds to the ribonucleotide reductase enzyme to prevent the synthesis of DNA and RNA. This drug also has anticancer properties, but it is not active against bacterial infections.
Pureza:Min. 95%5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
CAS:5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is an antiviral and anticancer agent that inhibits the replication of RNA and DNA. It inhibits viral infection by inhibiting the synthesis of viral genomes, which are made up of DNA or RNA. 5'-Azido-N6-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel modified nucleoside analog that blocks the incorporation of ribonucleotides into viral DNA or RNA. The drug has been shown to be effective against Hepatitis B, Hepatitis C, HIV, and other viruses. This compound can also be used as a chemotherapeutic agent for cancer treatment due to its inhibition of DNA synthesis.Fórmula:C18H24N8O5Pureza:Min. 95%Peso molecular:432.43 g/mol5-O-Tritylinosine
CAS:5-O-Tritylinosine is a modified nucleoside that has shown anticancer and antiviral properties. It is the monophosphate ester of 5-methyluracil and has been shown to inhibit DNA synthesis in vitro. 5-O-Tritylinosine has also been shown to inhibit the replication of herpes simplex virus type 1, which may be due to its ability to inhibit viral DNA polymerase.Fórmula:C29H26N4O5Pureza:Min. 95%Peso molecular:510.54 g/mol6-Methyl-thio-guanosine
CAS:6-Methyl-thio-guanosine is a guanine analog that has been used for the treatment of asthma. It was found to be effective in reducing the number of neutrophils and responsiveness of these cells to stimuli. 6-Methyl-thio-guanosine is able to reduce the number of neutrophils in the airway and decrease the amount of sputum produced by patients with chronic obstructive pulmonary disease. 6-Methyl-thio-guanosine also prevents the release of mediators from these cells, which are important in inflammation. This drug has been shown to have an effect on bronchial epithelial cells, slowing their growth and increasing their ability to resist damage. 6-Methyl-thio-guanosine can be administered by inhalation or orally, through microlenses or expansion devices, or by suctioning bronchial secretions. Treatment may also involve injection directly into lung tissue using a bronFórmula:C11H15N5O4SPureza:Min. 95%Peso molecular:313.33 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite is an activator that is used in the synthesis of DNA, RNA, and other nucleic acids. It has antiviral, anticancer, and antimicrobial activities. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite is a novel compound that has been modified to improve its activity as an activator. This activator is provided at high purity and is suitable for research purposes.Fórmula:C46H51IN5O8PPureza:Min. 95%Forma y color:PowderPeso molecular:959.83 g/mol1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil
1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil is a modified nucleoside that is an activator of DNA synthesis. It inhibits the activity of an enzyme called thymidine kinase and prevents the formation of the prodrug 5-fluorouracil. 1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-D-arabinofuranosyl)uracil has been shown to be active against a variety of cancer cells, including leukemia, skin cancer, and breast cancer. This drug also has antiviral and antimetabolite properties.Fórmula:C23H19N2O7FPureza:Min. 95%Peso molecular:454.4 g/mol8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine
Producto controlado8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine is a novel, diphosphate nucleoside with antiviral and anticancer activity. It has been shown to activate the transcription of genes that are involved in cell growth and differentiation. This drug also inhibits the synthesis of viral DNA by binding to the viral DNA polymerase, thereby inhibiting its function. 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine can be used as a phosphoramidite for the preparation of oligonucleotides for use in gene therapy.
Fórmula:C22H17N6O4D5Pureza:Min. 95%Forma y color:PowderPeso molecular:439.48 g/mol5'-Tosyl-2'-deoxyadenosine
CAS:5'-Tosyl-2'-deoxyadenosine is a synthetic, novel nucleoside that has antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits protein synthesis by blocking the enzyme ribonucleotide reductase. 5'-Tosyl-2'-deoxyadenosine is not active against Mycobacterium tuberculosis or Mycobacterium avium complex due to the lack of phosphoramidite incorporation into DNA. 5'-Tosyl-2'-deoxyadenosine is a high purity, high quality product that can be used as an antiviral agent or anticancer drug.Pureza:Min. 95%5-Azido-2'-deoxyuridine
CAS:5-Azido-2'-deoxyuridine is a diazonium salt that inhibits the replication of DNA. This compound is synthesized using natural compounds, including 5-azidouracil and formamide. The structure of this compound has been shown to be chromatographically similar to uridine and binds to DNA in vitro. It also has been shown to have biological properties that inhibit the growth of trichomonas vaginalis and dna replication. 5-Azido-2'-deoxyuridine is not very stable in dimethylformamide but can be stored at −20°C for up to two years.Pureza:Min. 95%6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (BMPT) is a synthetic cytokinin that belongs to the group of 6-benzylaminopurines. BMPT is an inhibitor of cytokinin receptor kinases, as it is a benzyl uracil derivative. BMPT can be used as a building block for the synthesis of other compounds and has been used as an inhibitor of cell growth in various organisms.
Fórmula:C12H13N3O2Pureza:Min. 95%Peso molecular:231.25 g/mol2',3'-Dithiouridine
CAS:2',3'-Dithiouridine is a triamide that is synthesized from uridine and chloroacetic acid. The dimeric form of this compound has been shown to be the most stable and yields are high. 2',3'-Dithiouridine can be prepared by the reaction of uridine with chloroacetyl chloride in DMSO at room temperature. The disulfide linkage between the two thiouridines is stereospecifically oriented in a cis conformation. The synthesis of 2',3'-dithiouridine from uridine and chloroacetic acid is achieved by an efficient procedure that gives high yields. This synthetic pathway also produces a crystalline, cyclic, sodium salt form of 2',3',4'-trihydroxypentane-1,5-dione that has not been previously reported.Fórmula:C9H12N2O4S2Pureza:Min. 95%Peso molecular:276.33 g/mol5'-O-Acetyllamivudine
CAS:5'-O-Acetyllamivudine is an antiviral agent that has been shown to have antiretroviral activity against HIV-1 and influenza A virus. It is a nucleoside analog that inhibits the synthesis of viral DNA by competitively inhibiting the enzyme DNA polymerase. 5'-O-Acetyllamivudine is also used as an anticancer drug, which may be due to its ability to inhibit DNA replication in tumor cells.Fórmula:C10H13N3O4SPureza:Min. 95%Peso molecular:271.29 g/mol3'-Azido-2'-deoxy-5'-O-DMT-thymidine
CAS:3'-Azido-2'-deoxy-5'-O-DMT-thymidine is a novel and potent activator of ribonucleotide reductase. It has been shown to be an effective inhibitor of DNA synthesis and antiviral agent, with a low cytotoxicity profile. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine is synthesized from DMT, which is readily available in the form of its monophosphate or diphosphate. The compound has been shown to inhibit viral replication by inhibiting viral reverse transcriptase activity. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine also inhibits DNA synthesis in cancer cells.Fórmula:C31H31N5O6Pureza:Min. 95%Peso molecular:569.61 g/mol4’-a-C-Methyluridine
CAS:4' - a-C-Methyluridine is a modified nucleoside that is used as a building block in the synthesis of DNA. It can be used for the treatment of viral infections and cancer. 4' - a-C-Methyluridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. 4' - a-C-Methyluridine also has anticancer activity, which may be due to its ability to inhibit proliferation of cells by blocking the synthesis of DNA and RNA.
Pureza:Min. 95%Cytidine 3',5'-bisphosphate sodium
CAS:Cytidine 3',5'-bisphosphate sodium is a phospholipid that is found in the cell membrane of gram-positive bacteria. Cytidine 3',5'-bisphosphate sodium has been shown to be produced by the enzyme phosphatidylcholine synthase, which converts phosphatidylethanolamine and cytidine 5'-monophosphate into phosphatidylcholine and cytidine 3',5'-bisphosphate. The presence of this compound in the cell membrane may be an indication of long-term survival and growth under laboratory conditions. It is also present in the ribosomal RNA of type strain organisms.Fórmula:C9H15N3O11P2•NaxPureza:Min. 95%Peso molecular:403.18 g/mol3'-Deoxy-3'-C-methylcytidine
CAS:3'-Deoxy-3'-C-methylcytidine is a monophosphate nucleotide that is used as an activator for DNA synthesis. It is a novel, synthetic nucleoside with high purity and high quality. 3'-Deoxy-3'-C-methylcytidine has been shown to inhibit viral replication, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1 (HSV-1) and Epstein Barr virus (EBV) in cell culture. It also inhibits the growth of cancer cells in vitro by inhibiting the synthesis of DNA, RNA, and protein.
Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.24 g/mol2-(Butylthio)pyrimidine-5-carbaldehyde
CAS:2-(Butylthio)pyrimidine-5-carbaldehyde (BTPCA) is a neutralizing agent that inhibits the proliferation of cancer cells by binding to their cell membranes. It binds to the membrane and blocks the cyclic AMP receptor, thereby inhibiting the growth of cells. BTPCA has been shown to be effective in killing CD4+ T cells and may have therapeutic potential for autoimmune diseases. BTPCA also has diagnostic potential, as it can be used to detect epidermal growth factor receptors on cell membranes.
Fórmula:C9H12N2OSPureza:Min. 95%Peso molecular:196.27 g/mol8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine
CAS:Producto controlado8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine) is a modified nucleoside that is used as an antiviral agent. It is not active against DNA viruses but has been shown to inhibit the replication of RNA viruses such as human immunodeficiency virus type 1 (HIV). 8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine has been found to be more effective than acyclovir (Zovirax), a commonly used antiviral drug. This nucleoside also has anticancer properties, which may be due to its ability to inhibit the synthesis of DNA and RNA.Fórmula:C23H20D3N9O4Pureza:Min. 95%Peso molecular:492.5 g/mol3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine
3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine is a novel, phosphoramidite monophosphate nucleoside. It is synthesized by reacting deoxydinucleosides with 3',5'-di-O-acetyl-N4-benzoyl-2'-deoxycytidine in the presence of a coupling agent. The product has been shown to be an excellent activator for DNA polymerases and may have antiviral effects. The chemical name of this compound is 2',3'-dideoxyadenosine 5' -triphosphate N4 -(beta, beta, beta, beta,-triethoxypropionyl) benzoyl ester.
Fórmula:C20H21N3O7Pureza:Min. 95%Peso molecular:415.41 g/mol
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