Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine
2-Amino-benzoyl-9-(5'-O-DMT-b-D-ribofuranosyl)purine is an anticancer and antiviral agent. It has been shown to be active against many viruses, including herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, and human immunodeficiency virus type 1. This compound also exhibits antitumor activity in mice and rats.Fórmula:C38H35N5O7Pureza:Min. 95%Peso molecular:673.71 g/mol5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution
5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution is a monophosphate nucleoside and an antiviral agent that inhibits viral DNA synthesis by inhibiting the activity of ribonucleotide reductase. The drug has been shown to be effective against herpes simplex virus, varicella zoster virus, and cytomegalovirus. It also has been shown to have anticancer activity in vitro and in vivo, which may be due to its ability to inhibit DNA synthesis.Fórmula:C9H13N2O11P2BPureza:Min. 95%Peso molecular:397.96 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranosyl 5'-triphosphate
CAS:4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a novel nucleoside analog that has been shown to have antiviral and anticancer activities. It acts as an activator of DNA polymerase, which results in the incorporation of deoxyribonucleotides into the growing DNA strand. This compound also inhibits DNA synthesis by competing with natural substrates for the enzyme ribonucleotide reductase. 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a modified nucleoside that has been synthesized by replacing the phosphate group with diphosphate group on the sugar moiety. The chemical name for this compound is 4-(2'-deoxy-βFórmula:C17H22N5O13P3Pureza:Min. 95%Peso molecular:597.3 g/mol2'-Deoxyadenosine-5'-carboxylic acid
CAS:dA oxidised at the 5'-position.Fórmula:C10H11N5O4Pureza:Min. 95%Peso molecular:265.23 g/mol2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate
2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate is a synthetic nucleoside analog with antiviral and anticancer activity. It is an analogue of cytidine, which is a component of DNA and RNA. 2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase in virus replication, which blocks the synthesis of viral proteins. This drug also inhibits the growth of cancer cells by interfering with their ability to proliferate.Pureza:Min. 95%2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine
CAS:2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine (FMA) is an antiviral nucleoside that has been shown to inhibit the growth of human T lymphocytes, human hepatoma cells and mouse lymphoma L5178Y cells. It also inhibits the replication of HIV in vitro and has been shown to be effective against other viruses such as herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, varicella zoster virus and vaccinia. FMA is a phosphoramidite compound that can be used in DNA synthesis. It is also a monophosphate analog of arabinoadenosine that can be used as an activator of deoxyribonucleosides. This novel compound can be modified to synthesize diphosphates or phosphoramidites.
Fórmula:C11H14FN5O4Pureza:Min. 95%Peso molecular:299.26 g/mol5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine
5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine is a novel nucleotide analog with antiviral and anticancer properties. It is synthesized by reacting 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine with 2',3'-dideoxyadenosine in the presence of N,N-dimethylaminopyridine to form 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine 2',3'-dideoxyadenosine. The antiviral activity of this compound has been demonstrated in vitro against HIV and herpes viruses. 5'-O-DMT-N2,N1,N6 -trimethoxybenzoylguanosine 2',3' -dideoxyadenosine alsoFórmula:C34H35FN6O6Pureza:Min. 95%Peso molecular:642.68 g/mol2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide
2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide is a novel anticancer agent that has been shown to have potent antiviral and antiproliferative properties. It is a phosphoramidite monophosphate with a CAS number of 313214-62-0. This compound can be used in the synthesis of DNA and nucleosides due to its high purity and quality. 2DOTC has been shown to inhibit the growth of human cancer cells by targeting their DNA replication machinery. The mechanism of action for this drug is not fully understood, but it is believed that it may modify the activation function of some proteins involved in cell division.Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine is a synthetic nucleoside that is used in the synthesis of DNA, RNA and other nucleosides. The 2'-O-tert-butyldimethylsilyl group makes this nucleoside stable to hydrolysis by phosphodiesterases, which are enzymes that break down nucleic acids. This product is also a novel monophosphate analog of uridine and can be used as an activator for oligonucleotide synthesis. It is highly pure and has been modified with a trityl group to increase its stability. The CAS number for this product is 117136-35-3.Fórmula:C34H40N2O6SiPureza:Min. 95%Peso molecular:600.78 g/molN6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt
CAS:N6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt is a potent antiviral agent that has been shown to inhibit the replication of DNA. It is active against herpesviruses, including cytomegalovirus (CMV) and Epstein-Barr virus (EBV). The drug has also been shown to be effective in inhibiting the growth of human cancer cells. The structure of the molecule is novel and it inhibits viral replication by blocking the synthesis of dNTPs, which are needed for DNA replication. N6-Benzoyl-2'-deoxy-5-O-DMT adenosine 3'-phosphonate triethylammonium salt was found to be more effective than other nucleoside analogues at inhibiting EBV replication in vitro and in vivo.Fórmula:C38H35N5O8P·C6H16NPureza:Min. 95%Peso molecular:822.89 g/molN1-Methyladenosine hydroiodide
CAS:N1-Methyladenosine hydroiodide is a novel nucleoside analogue that inhibits viral replication by preventing the formation of viral DNA. It also inhibits the growth of cancer cells and is used as an anticancer drug. N1-Methyladenosine hydroiodide has been shown to be an activator of RNA polymerase II, increasing the production of messenger RNA (mRNA) in human cells. The phosphoramidite form of this compound is used for the synthesis of oligodeoxyribonucleotides, which are chemically modified in order to improve their stability and inhibit degradation by nucleases. N1-Methyladenosine hydroiodide is highly pure and has CAS No. 34308-25-3.Fórmula:C11H15N5O4·HIPureza:Min. 95%Peso molecular:409.18 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a synthetic nucleoside that has shown anticancer and antiviral properties. It was first synthesized in the early 1990s and it is structurally similar to adenosine monophosphate. The synthesis of this compound starts with 5-iodo-2'-deoxyuridine, which reacts with the 5'-O-dimethoxytrityl group to form 2'-deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite. This nucleoside is then reacted with a phosphate triester to form 2'-deoxy-5'-O-DMT-5-[3-(2,2,2,-trimethylpropanoyl)propyl]thymidylic acid diphosphate.Fórmula:C39H46IN4O8PPureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:856.7 g/mol6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one
CAS:6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one is a synthetic nucleoside that has been shown to have potent antitumor activity in leukemia. It inhibits the synthesis of DNA by chemically binding to the enzyme that catalyzes the formation of pyrimidine nucleosides from uridine, thereby preventing RNA and DNA synthesis. 6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one also reversibly binds to the template strand of dna and prevents replication. This drug is effective in treating chronic lymphocytic leukemia (CLL).Fórmula:C12H15N3O5Pureza:Min. 95%Peso molecular:281.26 g/mol5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine
CAS:5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine is a synthetic nucleoside analogue. It has been used as a research tool for studying the activity of the enzyme thymidine phosphorylase, which is involved in the regulation of DNA synthesis. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine was synthesized by condensing 1,6-dichlorobenzene with 2,3,4,6-tetraiodopyrimidine in the presence of potassium carbonate and zinc chloride. The thermal analysis showed that this compound exhibits high enthalpy and low entropy values. This means that it decomposes into products at high temperatures and has a relatively low reactivity.Fórmula:C12H14ClIN2O5Pureza:Min. 95%Peso molecular:428.61 g/mol5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine
CAS:5'-O-Acetyl-3'-azido-2',3'-dideoxy-N2-palmitoylguanosine is a novel antiviral and anticancer agent. It is an analogue of the natural nucleoside guanosine. It has been modified with an acetyl group at the 5' position of the pentose moiety and an azido group at the 2' and 3' positions of the ribose moiety. The acetyl group makes this compound more water soluble, which means it can be easily administered intravenously for treatment of cancer or infection.Fórmula:C28H44N8O5Pureza:Min. 95%Peso molecular:572.7 g/mol2-Chloro-2'-deoxy-2'-fluoroadenosine
CAS:2-Chloro-2'-deoxy-2'-fluoroadenosine is an antiviral agent that is used in the treatment of hepatitis B and C. It has been shown to inhibit the synthesis of diphosphate, monophosphate, and ribonucleotides. 2-Chloro-2'-deoxy-2'-fluoroadenosine also inhibits DNA synthesis and has anticancer activity. This nucleoside is a modified form of adenosine with a fluorine atom at position 2' on the ribose sugar ring.
Pureza:Min. 95%2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a novel nucleoside that has shown anticancer activity. It is a modified deoxyribonucleoside with an N2,N8-di-DMF group attached to the 2' position of the ribose and a 5'-O-DMT group at the 8 position of the ribose. The compound binds to DNA and inhibits viral protein synthesis by preventing RNA polymerase from initiating transcription. It also inhibits bacterial DNA gyrase, which results in inhibition of bacterial DNA replication. This product is synthesized using high purity chemical reagents and yields a high quality product that is free of contaminants.Fórmula:C46H59N10O7PPureza:Min. 95%Peso molecular:895.02 g/mol3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride
3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is a nucleoside that belongs to the class of diphosphates. It has been shown to be an anticancer agent and is used in the treatment of patients with hematological malignancies. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is synthesized from 5'-deoxyuridine monophosphate and amidites, which are modified phosphoramidites. This compound can be used as a building block for DNA synthesis by incorporating into a growing chain, or as an activator for DNA polymerases. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride has been shown to induce apoptosis, or programmed cell death, in cancer cells.Pureza:Min. 95%3'-O-Methyluridine-5'-triphosphate lithium salt - 100 mM in water
CAS:3'-O-Methyluridine-5'-triphosphate lithium salt is a nucleoside that inhibits viral replication and tumor growth. It is a modified form of uridine with an extra methyl group at the 3′ position. The phosphoramidite can be used as an activating reagent for the synthesis of DNA. 3'-O-Methyluridine-5'-triphosphate lithium salt can also be used in the production of antiviral drugs, anticancer drugs, and novel compounds for research purposes.Fórmula:C10H13N2O15P3Li4Pureza:Min. 98 Area-%Forma y color:Clear LiquidPeso molecular:521.9 g/mol8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt
CAS:8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt (8CPTcGMP) is a fluorescent compound that is used to study the localization of proteins in living cells. It has been shown to bind to polypeptides that are involved in apoptotic cell death and its binding can be used as an indicator of apoptosis. 8CPTcGMP binds to chaperones, which are proteins that assist protein folding and other cellular processes by preventing misfolding. Fluorescence resonance energy transfer (FRET) between 8CPTcGMP and a fluorophore attached to another molecule can be used to detect the presence of this protein. The genetic code for 8CPTcGMP is ACACTCA.Fórmula:C16H14ClN5O7PS·NaPureza:Min. 95%Peso molecular:509.79 g/mol
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