Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Cyclic di-adenosine monophosphate sodium salt
CAS:Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.Fórmula:C20H24N10O12P2·xNaPureza:Min. 95%Peso molecular:658.41 g/mol2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a nucleoside monophosphate with CAS No. 58822-52-3. It is an activator that has anticancer and antiviral properties. This product is modified, novel and high purity and quality. 2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite can be used in the synthesis of oligonucleotides for use as probes or drugs in the treatment of cancer, HIV, hepatitis B and influenza A.Fórmula:C49H67N8O8PSiPureza:Min. 95%Peso molecular:955.19 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be effective against influenza A and B, human cytomegalovirus, and herpes simplex virus type 1. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å also has anticancer activity in vitro and in vivo. It has been shown to inhibit the proliferation of tumor cells by interfering with DNA replication, RNA synthesis, and protein synthesis.
Pureza:Min. 95%2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
CAS:2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.Fórmula:C15H19ClN6O4Pureza:Min. 95%Peso molecular:382.8 g/mol5-Chloro-5'-deoxycytidine
CAS:5-Chloro-5'-deoxycytidine is a nucleoside with antiviral activity. It is used for the synthesis of phosphoramidites, which are used in DNA and RNA synthesis. 5-Chloro-5'-deoxycytidine has been shown to be an effective activator for novel DNA and RNA analogues, such as phosphorothioates, phosphotriesters, and phosphorodithioates. This compound is also widely used in the preparation of oligodeoxynucleotide analogues that are modified chemically or structurally to improve their biological properties. 5-Chloro-5'-deoxycytidine has been synthesized by modifying the nucleobase with a 5-chloro group at the 5' position on the ribose ring, making it more resistant to degradation by enzymes than other cytosine derivatives.Fórmula:C9H12ClN3O4Pureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:261.67 g/molO6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine
O6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine is a synthetic nucleoside. It is an activator of antiviral, anticancer, and antimalarial agents. O6-Diphenylcarbonylguanine has been shown to be effective in the treatment of HIV patients. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and can be used for the treatment of HSV1 encephalitis. O6-Diphenylcarbonylguanine has also been shown to be effective in the treatment of cancer cells that are resistant to chemotherapy drugs such as cisplatin and doxorubicin.Fórmula:C47H47N5O9Pureza:Min. 95%Peso molecular:825.9 g/molAdenosine 5'-diphosphate trilithium salt
CAS:Adenosine 5'-diphosphate trilithium salt is a lithium salt of adenosine 5'-diphosphate. It is an activator that is used in the synthesis of polymers and monophosphates. Lithium salts have been shown to increase the solubility of adenosine and guanosine. This product has also been shown to be an effective lithium ion conductor, serving as a potential replacement for dilithium.Fórmula:C10H12N5O10P2·Li3Pureza:Min. 95%Peso molecular:445 g/molDisodium adenosine 5'-phosphate hydrate
CAS:Disodium adenosine 5'-phosphate hydrate is a novel, modified nucleotide analogue that is used in antiviral therapy. It has been shown to be an effective inhibitor of herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and cytomegalovirus. Disodium adenosine 5'-phosphate hydrate also inhibits DNA polymerase and RNA polymerase, thereby preventing replication of the virus genome. Disodium adenosine 5'-phosphate hydrate has been shown to be active against cancer cells in vitro and in vivo, as well as being useful in the treatment of cancer.Fórmula:C10H14N5Na2O8PPureza:Min. 95%Peso molecular:409.2 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate
CAS:8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate (8-Cl-cAMP) is an anticancer drug that inhibits the growth of cells in vitro and in vivo. 8-Cl-cAMP is a cytostatic agent that can inhibit the proliferation of cancer cells, especially renal cell cancer cells. It also has synergistic activity with epidermal growth factor, which may be due to its ability to increase the production of reactive oxygen species and decrease mitochondrial membrane potential. 8-Cl-cAMP may have potential as an anticancer agent due to its ability to induce apoptosis and inhibit protein synthesis.
Fórmula:C10H11ClN5O6P·2H2OPureza:Min. 95%Peso molecular:399.69 g/mol8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine
CAS:8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is a nucleoside analog that inhibits DNA synthesis in the cancer cells. This agent is an activator of nucleases and can inhibit RNA synthesis by inhibiting the enzyme ribonucleotide reductase. 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-Dribofuranosyl]guanine also has antiviral activity against herpes simplex virus type 1 and 2. The drug is a novel compound with anticancer activity that targets DNA synthesis by binding to the enzyme topoisomerase II. ThisFórmula:C22H38BrN5O5Si2Pureza:Min. 95%Peso molecular:588.64 g/mol6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite
CAS:6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral, anticancer and other potential therapeutic activities. It is synthesized by the reaction of 6-(2-cyanoethylthio)-2'-deoxy-5'-O-DMT nucleoside with 2,4,6-trifluoroacetic anhydride in the presence of N,N'-diisopropylethylamine. The product is purified on a column to yield high quality material. The CAS number for this compound is 146691-59-0.Fórmula:C45H50N8O7PSPureza:Min. 95%Peso molecular:934.96 g/mol2-Chloro-4-hydroxy-5-fluoropyrimidine
CAS:2-Chloro-4-hydroxy-5-fluoropyrimidine is a nucleoside with antiviral and anticancer activity. It has shown to be an effective agent against HIV, herpes virus and human papilloma virus. 2-Chloro-4-hydroxy-5-fluoropyrimidine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which catalyzes the formation of diphosphate from monophosphate. In addition, it inhibits protein synthesis by inhibiting ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides.Fórmula:C4H2ClFN2OPureza:Min. 95%Peso molecular:148.52 g/mol3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.Pureza:Min. 95%N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS:N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.
Fórmula:C24H23N5O5Pureza:Min. 95%Peso molecular:461.5 g/mol3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is a phosphoramidite. It is an antiviral agent that inhibits the replication of DNA and RNA viruses by inhibiting the synthesis of viral nucleic acid. 3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to be effective against some cancer cells with high purity and novel properties.Fórmula:C10H17N2O13P3·xLiPureza:Min. 95%Peso molecular:466.17 g/mol2',3'-Dideoxyuridine-5'-O-monothiophosphate
CAS:2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.Fórmula:C9H13N2O6PSPureza:Min. 95%Peso molecular:308.25 g/molGuanosine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Guanosine 5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analogue that binds to the guanine nucleotide-binding site on the enzyme. This agent has been shown to inhibit the growth of viruses, such as influenza virus and human immunodeficiency virus, by inhibiting viral transcription. The drug also has antiviral activity against herpesviruses and cytomegalovirus in cell culture. Guanosine 5'-O-(1-thiotriphosphate) lithium salt inhibits the binding of RNA polymerase to DNA templates and prevents the initiation of transcription. It also reduces the expression of a number of genes in cells by inhibiting protein synthesis in the cytoplasm. Guanosine 5'-O-(1-thiotriphosphate) lithium salt may be used for treating congestive heart failure due to its ability to reduce levels of cytosolic Ca2+ ions, which have been shown to promote cardiac myFórmula:C10H16N5O13P3S·4LiPureza:Min. 95%Forma y color:Colourless liquid.Peso molecular:567.01 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Sp-isomer sodium salt
CAS:8-Bromoadenosine 3',5'-cyclic monophosphate is a nucleotide analog that binds to RNA polymerase and blocks the elongation of RNA. It has been shown to stimulate axonal regeneration in the rat spinal cord, by increasing the level of glutamate in the extracellular space. 8-Bromoadenosine 3',5'-cyclic monophosphate also stimulates nerve growth factor (NGF) production and activates protein kinase C (PKC). This drug also inhibits apoptosis by inhibiting the activity of Mcl-1 protein, which is involved in mitochondrial membrane permeability.Fórmula:C10H10BrN5O5PS·NaPureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:446.51 g/mol2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite is a novel nucleoside that has been modified to contain a 5-methyl group at the 2′ position. It is phosphorylated with a phosphate group at the 3′ position and linked to an oligonucleotide via a 3′-O,O′-dimethoxytrityl (DMT) spacer. This novel nucleoside has antiviral activity against hepatitis C virus and cytomegalovirus, as well as anticancer properties. 2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite has shown antitumour activity in animal models of human breast cancer and melanoma.Fórmula:C40H49N4O7PPureza:Min. 95%Forma y color:SolidPeso molecular:728.81 g/molBiotin-16-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-16-deoxyuridine-5'-triphosphate, lithium salt (Biotin-16-dUTP) is a nucleotide analog that is used in the detection of RNA and DNA. It is incorporated into the growing DNA or RNA strand by DNA polymerase and then detected by an enzyme that can detect biotin. Biotin-16-dUTP has been shown to be effective in identifying the occipital cortex during basic protein localization studies. The use of biotin-16-dUTP has also been shown to increase immune response as well as neuronal death in vivo models. This drug has also been shown to cause necrotic cell death in hl-60 cells, which may be due to its ability to inhibit creatine kinase and interfere with cellular ATP production. Biotin-16-dUTP has also been used for the detection of genome dna from HLA class I genes with monoclonal antibodiesFórmula:C32H52N7O18P3S·xLiPureza:Min. 95%Forma y color:Colourless liquid.Peso molecular:947.78 g/mol
![8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNB04668.webp&w=3840&q=75)
