Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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2'-Deoxy-2'-fluoroadenosine-5'-monophosphate
CAS:<p>2'-Deoxy-2'-fluoroadenosine-5'-monophosphate is a nucleotide that is used as an anthelmintic drug. It inhibits the synthesis of fatty acids and ATP levels in tissue culture cells. This nucleotide has also been shown to have immunomodulatory effects, which may be due to its ability to bind to receptor activity. 2'-Deoxy-2'-fluoroadenosine-5'-monophosphate binds with high affinity to the response elements of transcription factors such as NF-κB and AP1, which are involved in the regulation of gene expression and inflammatory responses.</p>Fórmula:C10H13FN5O6PPureza:Min. 95%Peso molecular:349.21 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose
CAS:4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.Fórmula:C17H19N5O4Pureza:Min. 95%Peso molecular:357.36 g/mol2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite
CAS:2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite is a synthetic nucleoside analog that has been modified to contain a triphosphate group. It is used in the synthesis of DNA or RNA. The compound is synthesized from 2,4-dichloro-N-(2,6-dimethoxybenzyl)phenylamine, which was reacted with ethyl (3-[(trifluoroacetyl)amino]propanoate) and deoxythymidine 3'-monophosphate. The CAS number for this product is 851520-76-8.Pureza:Min. 95%2’,5’-Dideoxy-5’-iodouridine
CAS:<p>2’,5’-Dideoxy-5’-iodouridine is an antiviral drug that inhibits DNA synthesis. It is a modified nucleoside analog with a phosphoramidite derivative of the natural ribonucleosides and deoxyribonucleosides. This drug is synthesized through the reaction of 2’,5’-dideoxyadenosine with 5-iodo-2-deoxyuridine in the presence of a strong base such as sodium hydride. The resulting product has a high purity, high yield, and can be used for the synthesis of DNA. 2’,5’-Dideoxy-5’-iodouridine also has anticancer properties and has been shown to inhibit cell growth in vitro at concentrations ranging from 0.1 to 1 μM.</p>Pureza:Min. 95%3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine
3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine is a novel, modified nucleoside. This product is an activator of the ribonucleotide reductase enzyme and is used as a precursor in the synthesis of deoxyribonucleosides. It has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It has also been shown to have anticancer properties, as it inhibits DNA synthesis and tumor cell proliferation without affecting healthy cells. 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT uridine is synthesized from 5-(3,4,5)-trimethoxybenzaldehyde, 2′(2,6 dichloro)amino]methyl]benzeneacetic acid methyl ester and 5Pureza:Min. 95%3'-Deoxy-5'-O-trityluridine
CAS:<p>3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.</p>Fórmula:C28H26N2O5Pureza:Min. 95%Peso molecular:470.53 g/molN2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine
CAS:N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is a novel and potent anticancer nucleoside with antiviral activity. It is an analog of 2'-deoxy-5'-O-DMT guanosine, which was reported to be the first phosphoramidite nucleoside. N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is an excellent candidate for DNA synthesis and has been shown to inhibit viral replication. This product is also of high purity and high quality, and can be used in research applications.Fórmula:C38H35N5O7Pureza:Min. 95%Peso molecular:673.71 g/mol5-Azido- 2'- deoxycytidine
CAS:<p>5-Azido-2'-deoxycytidine is a high purity, novel, modified, and synthesized nucleoside with anticancer and antiviral properties. It is a diphosphate that is used in the synthesis of DNA as an activator. 5-Azido-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and to be active against influenza virus.</p>Fórmula:C9H12N6O4Pureza:Min. 95%Peso molecular:268.23 g/mol5'-O-DMT-thymidine phosphoramidite dimer
5'-O-DMT-thymidine phosphoramidite dimer is a novel, synthetic nucleoside that can be used for the treatment of cancers. It is an antiviral and antibacterial agent that has been shown to have cytotoxic effects against cancer cells. 5'-O-DMT-thymidine phosphoramidite dimer is not active against bacteria or viruses that are resistant to other nucleoside analogues. This compound inhibits DNA synthesis by inhibiting the activity of DNA polymerase, which is required for the replication of DNA. The chemical structure of 5'-O-DMT-thymidine phosphoramidite dimer resembles thymidine monophosphate, but it has a different sugar group at the 5' position and contains two phosphate groups at the 3' position.Pureza:Min. 95%5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine
CAS:5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is a modified nucleoside analog that inhibits the growth of viruses. It has been shown to be active against herpes simplex virus type 1 and 2, varicella zoster virus, cytomegalovirus, and Epstein-Barr virus. This drug is used as an antiviral medication in the treatment of viral infections.Fórmula:C24H26N4O4Pureza:Min. 95%Peso molecular:434.5 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt
<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt is a nucleoside that is modified with a 2,2,2-trifluoroethoxycarbonyl group on the 5' position of the sugar moiety. It is an activator for phosphoramidites in DNA synthesis and has been shown to have anticancer activity. It is also used as an antiviral agent and to treat HIV and herpes virus infections. This compound has a molecular weight of 439.5 g/mol and its CAS number is 62273-03-3.</p>Fórmula:C34H32FN2O10·C6H16NPureza:Min. 95%Forma y color:SolidPeso molecular:749.84 g/mol5-Fluorescein dT phosphoramidite
5-Fluorescein dT phosphoramidite is a novel modified nucleoside that has antiviral, activator, and anticancer properties. It is an analog of fluorouracil with a 5-fluorescein group at the 5' position. This phosphoramidite is synthesized from 2',3'-dideoxyuridine 5'-triphosphate and fluorescein diphosphate. It can be used to bind to DNA and inhibit viral replication. Other anticancer effects may be due to its ability to activate DNA synthesis by binding to deoxyribonucleosides or ribonucleosides in DNA. 5-Fluorescein dT phosphoramidite has high purity and quality, making it suitable for use in nucleotide sequencing, mutagenesis studies, and other applications requiring high purity nucleosides.Pureza:Min. 95%2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt
2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is an antiviral nucleotide analog that has been modified to have a novel structure. It is phosphorylated in vivo to form 2'-deoxyadenosine 5'-a-thiotriphosphate. The nucleoside can inhibit viral DNA synthesis and help prevent the spread of HIV, herpes virus type I, herpes virus type II, influenza virus, and other viruses. This compound also has anticancer activity and has been shown to be effective against leukemia cells.Pureza:Min. 95%Guanosine 3',5'-diphosphate tetralithium salt
CAS:Guanosine 3',5'-diphosphate tetralithium salt is a nucleoside that has antiviral and anticancer properties. It is synthesized by reacting guanosine with lithium tetrabutylammonium tetraiodide. This nucleotide can be used as a precursor for DNA synthesis, deoxyribonucleosides, and phosphoramidites. Guanosine 3',5'-diphosphate tetralithium salt has been shown to activate the synthesis of proteins in the absence of adenosine triphosphate (ATP).Fórmula:C10H11Li4N5O11P2Pureza:Min. 95%Peso molecular:466.93 g/mol5'-O-Trityl-3'-b-hydroxythymidine
CAS:<p>5'-O-Trityl-3'-b-hydroxythymidine is a nucleoside that is synthesized by the reduction of a pyrimidine with xylene. This molecule has been shown to have antibacterial activity, and also activates p53 in human cells. 5'-O-Trityl-3'-b-hydroxythymidine has been shown to inhibit the growth of cancer cells in a dose dependent manner. The functional theory for this finding is that 5'-O-Trityl-3'-b-hydroxythymidine may bind to DNA, preventing RNA polymerase from transcribing DNA into mRNA.</p>Fórmula:C29H28N2O6Pureza:Min. 95%Peso molecular:500.54 g/mol6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine
CAS:6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine is an anticancer drug that belongs to the class of nucleosides. It inhibits DNA and RNA synthesis by blocking the incorporation of nucleotides into DNA or RNA. This drug may also inhibit viral replication by blocking viral polymerase activity. 6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine has been shown to be a potent activator of phosphoramidites, which are used in chemical synthesis. This novel compound is synthesized using modified diphosphate chemistry and purified to high purity.Fórmula:C11H12ClN3O4Pureza:Min. 95%Peso molecular:285.68 g/mol5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å
5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å is a nucleoside analog that has been shown to be an effective anticancer agent. It has been shown to activate the cellular DNA synthesis by stimulating the phosphorylation of RNA polymerase II, which is involved in the transcription of DNA. 5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å also inhibits viral replication and may be effective against AIDS. This nucleoside analog induces antiviral effects by inhibiting the synthesis of viral dsDNA.Pureza:Min. 95%2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)
CAS:<p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C56H61N8O12PPureza:Min. 95%Peso molecular:1,069.1 g/molUridylyl-3'-5'-cytidine ammonium salt
<p>Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.</p>Fórmula:C18H27N6O13PPureza:Min. 95%Peso molecular:566.41 g/mol7H-Pyrrolo[2,3d]pyrimidine
CAS:7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has aFórmula:C6H5N3Pureza:Min. 95%Peso molecular:119.12 g/mol
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