Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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N6-Acetyl-2'-deoxyadenosine
CAS:N6-Acetyl-2'-deoxyadenosine is an antiviral and anticancer nucleoside. It is a novel modified nucleoside that has been synthesized with a high degree of purity. N6-Acetyl-2'-deoxyadenosine is active against HIV, Hepatitis C, and other viruses, as well as cancer cells. It also inhibits the activity of bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. N6-Acetyl-2'-deoxyadenosine has a phosphoramidite structure and is synthesized from 2'-deoxyribonucleosides.Fórmula:C12H15N5O4Pureza:Min. 95%Peso molecular:293.28 g/molN-Acetyl-2'-deoxy-2',2'-difluorocytidine
CAS:N-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog. It is phosphorylated at the 5' position and converted to a monophosphate by adenylyl cyclase, which is an enzyme that catalyzes the conversion of ATP to cyclic AMP. This nucleoside analog has antiviral activity in vitro and in vivo against HIV-1. It also has been shown to inhibit DNA replication of human cells infected with herpes simplex virus type 1 (HSV-1).Fórmula:C11H13F2N3O5Pureza:Min. 95%Peso molecular:305.23 g/molAbacavir 5'-phosphate
CAS:Abacavir 5'-phosphate is a nucleoside analog that inhibits the replication of the herpes virus by covalently binding to the viral DNA polymerase and blocking its ability to polymerize dNTPs. Abacavir 5'-phosphate's anti-viral potency has been shown in vivo using a model with herpes simplex virus, and it has been shown to inhibit viral replication in cell culture. The drug also reacts with cellular components such as proteins, lipids, and nucleic acids, which may lead to drug reactions. Abacavir 5'-phosphate is chemically stable, so it can be subjected to analytical methods without degradation. It is an analog of zidovudine (AZT).
Fórmula:C14H19N6O4PPureza:Min. 95%Peso molecular:366.31 g/mol2'-O-Methyladenosine 5'-monophosphate triethylammonium salt
CAS:2'-O-Methyladenosine 5'-monophosphate triethylammonium salt is an antiviral nucleoside that is used in the treatment of hepatitis B and C. It is a modified nucleoside that inhibits the replication of RNA by binding to the enzyme ribonuclease, which plays a vital role in the synthesis of DNA. 2'-O-Methyladenosine 5'-monophosphate triethylammonium salt also has anticancer properties and can inhibit DNA synthesis. This compound is a novel phosphoramidite building block for oligonucleotide synthesis and has been shown to be an activator for deoxyribonucleosides.Fórmula:C11H16N5O7PPureza:Min. 95%Peso molecular:361.25 g/mol2'-Deoxyinosine-5'-triphosphate sodium
CAS:2'-Deoxyinosine-5'-triphosphate sodium is a nucleoside that is used as an antiviral, anticancer and novel drug. It inhibits viral replication by inhibiting DNA synthesis in the cell. 2'-Deoxyinosine-5'-triphosphate sodium binds to viral RNA polymerase, preventing the enzyme from creating new DNA strands. This prevents the virus from replicating and spreading to other cells in the body. 2'-Deoxyinosine-5'-triphosphate sodium has been shown to inhibit cancer growth by binding to DNA, which prevents it from dividing and creating new cells. This drug also has antiviral activity against HIV and Herpes Simplex Virus Type 1 (HSV1). 2'-Deoxyinosine-5'-triphosphate sodium is typically used as a buffer solution for peptide synthesis or as a chemical intermediate for various organic syntheses.Fórmula:C10H15N4O13P3·xNaPureza:Min. 95%Forma y color:White PowderPeso molecular:492.17 g/molValopicitabine
CAS:Valopicitabine is a prodrug that is converted to its active form, 3'-deoxy-3'-methylvalopicitabine, in the body. Valopicitabine inhibits viral replication by a mechanism that is not yet fully understood. It has been shown to inhibit NS3 protease and induce an interferon response. Valopicitabine has also been shown to inhibit Toll-like receptor 4 (TLR4) activity and elicit an antiviral response. Valopicitabine has low bioavailability, which may be due to its high lipophilicity.Fórmula:C15H24N4O6Pureza:Min. 95%Peso molecular:356.37 g/mol[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is an antiviral and anticancer nucleoside phosphoramidite. It is synthesized by reacting the purified 6-(N4-benzoylcydin-1-yl) morpholine with dimethyl phosphorochloridate in pyridine at room temperature. This novel monophosphate nucleoside has been shown to be efficacious against human immunodeficiency virus (HIV) and murine leukemia virus (MLV). The antiviral activity of [(2S,6R)-6-(N4-benzoylcydin-1-yl)-4-(tritylmorpholin]-2(1H)-yl]methyl dimethylphosphoramidochloridate is due to its ability
Fórmula:C37H37ClN5O5PPureza:Min. 95%Forma y color:PowderPeso molecular:698.15 g/mol1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole
CAS:Please enquire for more information about 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-nitro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C13H14N2O5Pureza:Min. 95%Peso molecular:278.26 g/mol5'-o-(4,4'-Dimethoxytrityl)-2'-deoxythymidine-3'-(methyl-N,N-diisopropyl)phosphoramidite
CAS:Please enquire for more information about 5'-o-(4,4'-Dimethoxytrityl)-2'-deoxythymidine-3'-(methyl-N,N-diisopropyl)phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C38H48N3O9PPureza:Min. 95%Peso molecular:721.8 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-monophosphate
CAS:10umol is approximately 5mg.2'-O-(2-Methoxyethyl)adenosine 5'-monophosphate is a nucleoside compound that has been phosphorylated in the 5'-position.Pureza:Min. 95%2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine
CAS:2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine (DBBA) is a modified nucleoside with anticancer, antiviral, and synthetic properties. It can be used as a building block for the synthesis of DNA, RNA, or other nucleotide analogues. DBBA has shown activity against certain cancer cells and has been found to inhibit the replication of HIV and herpes simplex virus type 1 in cell culture. DBBA is also known as 2',3'-Dibenzoyl-N6-benzoyladenosine.Fórmula:C31H25N5O7Pureza:Min. 95%Peso molecular:579.56 g/mol2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine
CAS:Please enquire for more information about 2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C14H19N5O4Pureza:Min. 95%Peso molecular:321.33 g/mol4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution is thio-base modified thymidine nucleotideFórmula:C10H17N2O13P3S·xLiPureza:Min. 95%Peso molecular:498.23 g/mol2',3'-Dehydro-5'-O-tritylthymidine
CAS:2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.Fórmula:C29H26N2O4Pureza:Min. 95%Peso molecular:466.54 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and
Fórmula:C11H17N4O13P3·xNaPureza:Min. 95%Peso molecular:506.19 g/mol5-Fluorouridine-5'-diphosphate sodium
CAS:5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.Fórmula:C9H13FN2O12P2•NaxPureza:Min. 95%Forma y color:PowderPeso molecular:423.16 g/mol2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water
CAS:2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water is a nucleotide analog that inhibits the synthesis of RNA. It is used for the treatment of cancer. This agent binds to DNA and prevents the formation of RNA by inhibiting the enzyme ribonucleotide reductase. 2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water also has a perchloric acid component, which may be responsible for its haematopoietic effects.
Fórmula:C9H14FN2O14P3·xNaPureza:Min. 95%Forma y color:PowderPeso molecular:486.13 g/molLauroyl coenzyme A potassium salt
CAS:Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymerFórmula:C33H55N7O17P3SK3Pureza:Min. 95%Forma y color:PowderPeso molecular:1,064.11 g/molDoubler phosphoramidite
CAS:Please enquire for more information about Doubler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C64H79N4O10PPeso molecular:1,095.31 g/mol2,2'-Anhydro-L-thymidine
CAS:2,2'-Anhydro-L-thymidine is an antiviral, anticancer agent and a synthetic nucleoside. It is a monophosphate that was first synthesized in 1967 and has been used as a potential antiviral agent. 2,2'-Anhydro-L-thymidine has been shown to be effective against the herpes simplex virus type 1 (HSV1). However, it does not inhibit viral nucleic acid synthesis or viral protein synthesis. It also does not inhibit the growth of tumor cells in culture.Fórmula:C10H12N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:240.21 g/mol
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