Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may beFórmula:C10H16N5O13P3·xLiPureza:Min. 95%Forma y color:Colorless Clear LiquidPeso molecular:507.18 g/mol3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine
3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.Fórmula:C28H33FN2O6SiPureza:Min. 95%Peso molecular:540.66 g/mol5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite
This is a phosphoramidite that is used in the synthesis of DNA. The chemical name for this compound is 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite. This compound has been shown to be an anticancer drug and has high purity, high quality, and novel properties.Fórmula:C52H62N7O10PPureza:Min. 95%Forma y color:White PowderPeso molecular:976.09 g/mol2-Methylthioadenosine-5'-triphosphate
CAS:2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.Fórmula:C11H18N5O13P3SPureza:Min. 95%Peso molecular:553.27 g/mol2-Methylsulfanyl-4-phenylpyrimidine
CAS:2-Methylsulfanyl-4-phenylpyrimidine is a heterocyclic compound that has been shown to be an effective anti-malarial agent. The drug inhibits the growth of malaria parasites by binding to the parasite's DNA and preventing its replication. 2-Methylsulfanyl-4-phenylpyrimidine also recycles the monocyclic pyrimidines, which are nucleophiles, and therefore can be used as a precursor for other drugs. 2-Methylsulfanyl-4-phenylpyrimidine is not very soluble in water but is soluble in organic solvents such as ethanol, propylene glycol, or acetone. It has also been found to form stable salts with perchlorate and guanidine.Pureza:Min. 95%2'-Amino-2'-deoxycytidine
CAS:2'-Amino-2'-deoxycytidine is a modified nucleoside, based on cytidine. In this compound 2'-hydroxyl group has been replaced by an amino group, which can change hydrogen bonding patterns potentially affecting how it interacts with biomolecules.Fórmula:C9H14N4O4Pureza:Min. 95%Forma y color:PowderPeso molecular:242.24 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite
CAS:A 5'-3’ “reverse” (or “inverse”) amidites
Fórmula:C47H52N7O7PPureza:Min. 95%Peso molecular:857.93 g/mol5'-O-Tosylthymidine
CAS:5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Fórmula:C17H20N2O7SPureza:Min. 95%Peso molecular:396.42 g/mol[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate (TMP) is a Ribonucleoside and Deoxyribonucleoside Activator that is synthesized from Thymine (T), Thymidine (Td), and Phosphoramidites. TMP is a novel synthetic derivative of thymine with the ability to activate DNA synthesis reactions. TMP has been shown to provide high quality nucleotides with high purity in a single step reaction.Fórmula:C31H34ClN4O5PPureza:Min. 95%Forma y color:White To Light (Or Pale) Red SolidPeso molecular:609.05 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Fórmula:C32H74N7O12P3SPureza:Min. 95%Peso molecular:873.96 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-α-thiotriphosphate sodium
2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.Fórmula:C13H18N5Na4O13P3SPureza:Min. 95%Peso molecular:669.25 g/molFludarabine phosphate
CAS:Fludarabine phosphate is an antileukemic drug that inhibits DNA polymerase α and β, as well as other enzymes in the nucleotide synthesis pathway. It is used to treat patients with chronic myelogenous leukemia (CML) who have developed resistance to other treatments. Fludarabine phosphate has been shown to induce a cytotoxic effect against tumor cells by binding to ATP-binding cassette transporter proteins on the cell membrane and inhibiting intracellular targets such as DNA, RNA, and protein synthesis. Fludarabine phosphate has also been shown to inhibit the growth of tumor cells through synergistic interactions with other anticancer drugs such as hydroxyurea or busulfan, which may be due to its ability to inhibit enzyme activities such as erythrocyte alkaline phosphatase.
Fórmula:C10H13FN5O7PPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:365.21 g/molThymidine-3',5'-diphosphate disodium salt
CAS:Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Fórmula:C10H14N2Na2O11P2Pureza:Min. 95%Forma y color:PowderPeso molecular:446.15 g/mol2',3'-O-Isopropylideneinosine
CAS:2',3'-O-Isopropylideneinosineis a nucleoside for use in research applications
Fórmula:C13H16N4O5Pureza:Min. 95%Forma y color:PowderPeso molecular:308.3 g/mol4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester
CAS:Focuses is a chemical compound that does not have any known commercial or industrial uses.Pureza:Min. 95%Polyadenylic acid potassium
CAS:Please enquire for more information about Polyadenylic acid potassium including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:(C10H14N5O7P)x•KxPureza:85% Min2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite
CAS:2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is a fluorescent DNA probe that can be used for the detection of specific sequence mismatches in target DNA. This probe contains a linker, which is a short oligonucleotide, and a fluorescent label at the 5' end. The probe has been designed to hybridize to its complementary sequence in the target DNA. When it detects mismatches, it becomes fluorescent because of increased stacking interactions between the bases. This allows for easy detection of mismatches in target sequences without the need for PCR amplification or gel electrophoresis.Fórmula:C42H53N6O7PPureza:Min. 95%Forma y color:PowderPeso molecular:784.88 g/mol5-Iodocytidine 5'-triphosphate sodium salt - 100mM solution
CAS:5-Iodocytidine 5'-triphosphate sodium salt is a novel antiviral agent. It is the sodium salt of 5-iodocytidine 5'-triphosphate and is used to inhibit viral replication. It inhibits RNA synthesis by interfering with the incorporation of deoxyribonucleosides into the growing DNA chain, which blocks DNA synthesis. This inhibition prevents virus production and may be useful in treating cancer.Fórmula:C9H15IN3O14P3Pureza:Min. 95%Peso molecular:609.05 g/mol2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite
2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite is a 5'-3’ “reverse” (or “inverse”) amidite.Fórmula:C44H54N7O8PPureza:Min. 95%Peso molecular:839.94 g/molAdenylyl-3'-5'-guanosine sodium salt
CAS:3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--> 3'--O--(CH2)4--CONH2 + H3PO4
Fórmula:C20H24N10O11P·NaPureza:Min. 95%Peso molecular:634.43 g/mol
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