
Nucleósidos
Se han encontrado 3569 productos de "Nucleósidos"
Trebler phosphoramidite
CAS:Please enquire for more information about Trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C86H101N2O14PPeso molecular:1,417.7 g/mol3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution is the sodium salt of the monophosphate ester of 3'-amino-2',3'-dideoxy-5'-thiacytidine. It is used as an antiviral and antineoplastic agent. 3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution has been shown to be an activator of RNA polymerase II and DNA polymerase, which are enzymes that synthesize proteins and DNA, respectively. This drug also inhibits the synthesis of deoxyribonucleosides, diphosphates, and nucleosides. END>
Fórmula:C10H18N3O13P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:481.18 g/molUDP-N-azidoacetylglucosamine
CAS:UDP-N-azidoacetylglucosamine is a UDP sugar with an azide functional handle on the glucosamine making it suitable for modification via click chemistry.Fórmula:C17H26N6O17P2Pureza:Min. 95%Forma y color:PowderPeso molecular:648.37 g/mol5-Carboxymethyl-2-thiouridine
CAS:5-Carboxymethyl-2-thiouridine is a modified form of uridine that has been synthesized by the reaction of 5-carboxymethyluracil with thiourea. It is used in chemical biology to study protein synthesis and to analyze the structural changes that occur during this process. 5-Carboxymethyl-2-thiouridine has also been shown to be effective as a viral RNA polymerase inhibitor, preventing the synthesis of viral proteins and thus reducing viral replication. This drug is also used in chromatographic methods for separating amino acids, peptides, and proteins.Fórmula:C11H14N2O7SPureza:Min. 95%Peso molecular:318.3 g/mol2-Methyladenosine-5'-triphosphate
CAS:2-Methyladenosine-5'-triphosphate (2-MeATP) is an inhibitor of the purinergic receptor P2X. It is a competitive antagonist of ATP at the P2X receptor, blocking ATP binding and inhibiting ATP-mediated signal transduction. 2-MeATP has been shown to inhibit angiotensin-mediated hyperpolarization in wild type and mutant strains of M. smegmatis, as well as m. tuberculosis perfusion in mesenteric lymph nodes and vasoconstriction in wildtype and mutant strains of AT1 receptors.
Fórmula:C11H18N5O13P3Pureza:Min. 95%Peso molecular:521.21 g/mol3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.Fórmula:C9H17N4O12P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:466.17 g/mol5-(Carboxyhydroxymethyl)uridine methyl ester
CAS:5-(Carboxyhydroxymethyl)uridine methyl ester is a modified form of uridine that is used in biochemical reactions. It is found in the ovary, where it interacts with acidic environments to produce the corresponding hydroxymethyl derivatives. The hydroxymethyl derivatives are then converted to the corresponding 5-carboxy-hydroxymethyl derivatives by conjugates and modifications, which can be analyzed using various assays. 5-(Carboxyhydroxymethyl)uridine methyl ester has also been shown to have epigenetic effects on cellular activity and cancer.
Fórmula:C12H16N2O9Pureza:Min. 95 Area-%Forma y color:Slightly Yellow Clear LiquidPeso molecular:332.26 g/mol[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbomoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbamoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is a novel antiviral agent that is structurally related to the nucleoside analogues. It is synthesized by reacting an N2-(isobutyryl)O6-(diphenylcarbamoyl)guanin with 2,6-bis(trityl)morpholine and methyl dimethyl phosphite in dichloromethane. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), HSV type 2 (HSV2), and cytomegalovirus (CMV). [(2S,6R)-6-{N2-(Isobutyryl)-OFórmula:C48H48ClN8O6PPureza:Min. 95%Peso molecular:899.37 g/mol5-Carbamoylmethyl-2'-O-methyluridine
CAS:5-Carbamoylmethyl-2'-O-methyluridine is a nucleoside analog that inhibits the synthesis of proteins by inhibiting the translation process. It has been shown to be effective against tuberculosis and other mycobacterial diseases. 5-Carbamoylmethyl-2'-O-methyluridine binds to the ribosomal RNA, preventing protein synthesis and causing cell death. This drug has pleiotropic effects on cells, including inhibition of frameshifting, which is a mechanism used by some viruses to avoid immune responses. 5-Carbamoylmethyl-2'-O-methyluridine also interacts with cellular genes in response to stress (e.g., ultraviolet radiation). The mechanism of action for this drug is similar to that of 5-methoxycarbonylmethyl 2'-thiouridine (5MMCU), which inhibits protein synthesis by binding to the 30S ribosomal subunit and blocking the formation ofFórmula:C12H17N3O7Pureza:Min. 95%Forma y color:PowderPeso molecular:315.28 g/molLysidine
CAS:Derivative of cytidine found in tRNA which enhances translation fidelityFórmula:C15H25N5O6Pureza:Min. 95%Peso molecular:371.39 g/mol7-Deaza-3'-deoxyadenosine
CAS:7-Deaza-3'-deoxyadenosine is a synthetic nucleoside that is used in the synthesis of DNA. It has antiviral activity and is effective against HIV, herpes simplex virus and hepatitis B. 7-Deaza-3'-deoxyadenosine also has anticancer activity and can be used as a chemotherapeutic agent for leukemia, lymphoma, and breast cancer. This drug has been shown to inhibit the growth of cultured human tumor cells by inhibiting DNA synthesis through inhibition of DNA polymerase alpha and beta.Fórmula:C11H14N4O3Pureza:Min. 95%Peso molecular:250.25 g/mol5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Fórmula:C9H14N4O5Pureza:95%Forma y color:SolidPeso molecular:258.2313N6-Benzoyl-5'-O-trityl-adenosine
N6-Benzoyl-5'-O-trityl-adenosine is a novel nucleoside, which has been synthesized to be a phosphoramidite. It is an anticancer drug that inhibits the growth of tumor cells by competitively inhibiting the synthesis of DNA and RNA. In addition, N6-Benzoyl-5'-O-trityl-adenosine has antiviral properties, which may be due to its ability to inhibit viral DNA polymerase. This compound also shows high purity and quality.
Fórmula:C36H31N5O5Pureza:Min. 95%Peso molecular:613.66 g/mol5'-Amino-5'-deoxy-2'-O-methyluridine
5'-Amino-5'-deoxy-2'-O-methyluridine is a novel nucleoside analog with antiviral and anticancer properties. 5'-Amino-5'-deoxy-2'-O-methyluridine is an activator of the immune system, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase. This drug has shown activity against a variety of human tumor cell lines in vitro and in vivo. 5'-Amino-5'-deoxy-2'-O-methyluridine also inhibits the growth of several bacterial strains, including methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium avium complex.
Pureza:Min. 95%3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole
CAS:3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a nucleoside analog that is an antiviral and anticancer agent. It is a monophosphate, which has been shown to inhibit the replication of DNA by binding to the enzyme DNA polymerase. 3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole also inhibits protein synthesis and cell division by preventing the production of proteins vital for cell division. This drug has shown high purity and quality, as well as novel properties.
Fórmula:C41H36N2O5Pureza:Min. 95%Peso molecular:636.74 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)cytosine
1-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl) cytosine is a modified nucleoside that is phosphoramidite activated by the addition of a diphosphate. The diphosphate group on the sugar moiety may be hydrolyzed to form 1-(2'-deoxy-5'-O-DMT-b-D-xylofuranosyl)cytosine monophosphate. Cytidine is an antiviral and antifungal agent that is used in the treatment of herpes zoster, chronic myeloid leukemia, and other cancers. It has been shown to inhibit DNA synthesis and viral replication in vitro.
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Cytidine is an antiviral and antifungal agent that is used in the treatment of herpes zoster, chronic myeloid leukemia, and other cancers. It has been shown to inhibit DNAPureza:Min. 95%4’-C-Methyl-2-thiouridine
CAS:4’-C-Methyl-2-thiouridine is an activator that has anticancer properties. It is a modified nucleoside with antiviral and antifungal activities, which has been shown to inhibit the growth of human tumor cells in vitro. 4’-C-methyl-2-thiouridine is able to inhibit viral replication in vitro and has been shown to be active against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). Interestingly, this compound was found to have no effect on the intracellular levels of thymidine kinase or on cellular DNA synthesis.
Fórmula:C10H14N2O5SPureza:Min. 95%Peso molecular:274.29 g/mol5-(Azidomethyl)uridine
CAS:5-(Azidomethyl)uridine (5-AZA-U) is a cytosolic nucleoside analog that inhibits the replication of herpes simplex virus type 1 (HSV-1). It is resistant to degradation by cellular nucleases and is fluorescent, making it a clickable substrate for microscopy. 5-AZA-U has been shown to inhibit the transcription of viral DNA and the synthesis of viral proteins in mammalian cells. This drug has also been shown to be effective against cancer and hepatitis B virus (HBV). 5-AZA-U can be used as an antiviral agent because of its ability to inhibit the posttranscriptional gene expression of HSV-1. 5-(Azidomethyl)uridine is also an analog of uridine, which can be used to study intracellular signaling pathways that regulate proliferation, differentiation, or apoptosis in mammalian cells.
Fórmula:C10H13N5O6Pureza:Min. 95%Forma y color:PowderPeso molecular:299.24 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is an anticancer agent that acts by inhibiting the formation of DNA and RNA. It is a nucleoside analogue that has been modified to contain a benzoyl group at the 2' carbon atom, which leads to increased cytotoxicity. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is a synthetic nucleoside analogue with novel properties. It inhibits the synthesis of DNA and RNA in cells, which may be due to its ability to inhibit DNA polymerases and ribonucleases.
Fórmula:C39H54N5O8PSiPureza:Min. 95%Peso molecular:779.95 g/mol

