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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3567 productos de "Nucleósidos"

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  • N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite


    <p>N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesis</p>
    Fórmula:C38H52N5O8PSi
    Pureza:Min. 95%
    Peso molecular:765.93 g/mol

    Ref: 3D-PB08671

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  • 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-N2-isopropylguanosine is a nucleoside that is used as an activator for phosphoramidites in the synthesis of DNA. It is also an antiviral agent that inhibits the synthesis of RNA by inhibiting the enzyme RNA polymerase II. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine has been shown to have anticancer activity and can be used as a substitute for other nucleosides in the treatment of leukemia, lymphoma, and breast cancer. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine is synthesized from DMT and N2-(2-isopropyl)guanine.</p>
    Fórmula:C34H37N5O6
    Pureza:Min. 95%
    Peso molecular:611.7 g/mol

    Ref: 3D-ND09158

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  • 2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine


    <p>2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a modified nucleoside that inhibits the proliferation of cancer cells. It has been shown to be effective against HIV, Hepatitis B and C, influenza, herpes simplex virus type 1 and 2, and human cytomegalovirus. This drug is synthesized by phosphoramidite chemistry and is used as a DNA activator in the synthesis of oligonucleotides. 2'-Deoxy-2'-fluoro-2'-C-methyl-5-methyluridine is a novel compound that exhibits high quality with high purity.</p>
    Pureza:Min. 95%

    Ref: 3D-ND29434

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  • 2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite


    <p>2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a modified nucleoside analogue with anticancer activity. It is synthesized by reacting 2'-deoxy-N2-isobutyryl-5'-O-methylguanosine with diethyl chlorophosphate in the presence of tetrazole. This novel compound has been shown to have antiviral and antitumor activities as well as high affinity for DNA and RNA.</p>
    Fórmula:C43H52N7O7P
    Pureza:Min. 95%
    Peso molecular:809.91 g/mol

    Ref: 3D-PD09154

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  • N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine

    CAS:
    <p>N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.</p>
    Fórmula:C38H37N3O8
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:663.72 g/mol

    Ref: 3D-NB08370

    1g
    135,00€
    2g
    187,00€
    5g
    327,00€
    10g
    478,00€
  • BBQ-650-DT CEP

    CAS:
    <p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>
    Fórmula:C76H89N12O15P
    Pureza:Min. 95%
    Peso molecular:1,441.6 g/mol

    Ref: 3D-FLB55446

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  • Inosine 5'-triphosphate disodium

    CAS:
    <p>Inosine 5'-triphosphate disodium salt is a phosphoramidite that can be used as an activator for DNA synthesis. It also has antiviral and anticancer properties. Inosine 5'-triphosphate disodium salt is used in the synthesis of deoxyribonucleosides and other nucleotides.</p>
    Fórmula:C10H13N4O14P3•Na2
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:552.13 g/mol

    Ref: 3D-NI09674

    1g
    320,00€
    2g
    491,00€
    5g
    806,00€
    250mg
    182,00€
    500mg
    255,00€
  • 6-O-Methyl-2'-deoxyinosine

    CAS:
    <p>6-O-Methyl-2'-deoxyinosine is a modified nucleoside that inhibits the synthesis of DNA and RNA. It is also an anticancer agent, inhibiting the growth of tumor cells by arresting the cell cycle at the G1 phase. 6-O-Methyl-2'-deoxyinosine is a phosphoramidite for use in solid phase synthesis of oligodeoxynucleotides (ODN). This product has high purity, good quality, novel structures and excellent stability.<br>6-O-Methyl-2'-deoxyinosine can be used to inhibit viral replication by preventing viral DNA from being replicated into double stranded DNA. The antiviral activity of 6-O-methyl 2'-deoxyinosine against HIV has been demonstrated in vitro and in vivo using monophosphate forms.</p>
    Pureza:Min. 95%

    Ref: 3D-NM144752

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  • 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine

    CAS:
    <p>5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine is a novel nucleoside analogue that is an activator of the innate immune system. It is used for the treatment of cancer and viral infections. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has been shown to have anticancer activity against pancreatic, lung, breast, prostate, colon, and leukemia cells in vitro. This drug also inhibits influenza virus A/WSN/33 replication in cell culture by blocking the RNA polymerase complex at the initiation stage. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has also been shown to be active against herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1).</p>
    Pureza:Min. 95%

    Ref: 3D-NA02562

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  • 2'-Deoxycytidine HCl

    CAS:
    <p>2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.</p>
    Fórmula:C9H13N3O4·HCl
    Pureza:Min. 98 Area-%
    Forma y color:White Powder
    Peso molecular:263.68 g/mol

    Ref: 3D-ND02591

    5g
    476,00€
    10g
    632,00€
    25g
    894,00€
    50g
    1.260,00€
    100g
    1.883,00€
  • 2'-C-Methyluridine

    CAS:
    <p>2'-C-Methyluridine is a synthetic nucleoside analog derived from uridine, modified with a methyl group at the 2'-carbon of the ribose sugar. This small chemical change has important implications for RNA biology, antiviral drug development, and biochemical research, especially in targeting RNA viruses.</p>
    Fórmula:C10H14N2O6
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:258.23 g/mol

    Ref: 3D-NM07919

    1g
    345,00€
    2g
    509,00€
    5g
    804,00€
    10g
    1.213,00€
    500mg
    193,00€
  • N6-Isobutyryl-2'-O-methyladenosine


    <p>N6-Isobutyryl-2'-O-methyladenosine is a nucleoside that has antiviral, anticancer, and anti-inflammatory properties. It is an analog of adenosine that is used in the synthesis of DNA and RNA. It is modified by the incorporation of an iso-butyl group at the 2' position on the ribose ring. N6-Isobutyryl-2'-O-methyladenosine was first synthesized in 1962 and has been extensively studied due to its novel properties. The phosphoramidites are activated with tetrazole or triazole, which are both strong activators. This nucleoside can be synthesized in high purity (&gt;98%) through a modification of the conventional phosphorylation process.</p>
    Fórmula:C15H21N5O5
    Pureza:Min. 95%
    Peso molecular:351.36 g/mol

    Ref: 3D-NI08338

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  • 2-Amino-2'-deoxyadenosine

    CAS:
    <p>2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applications</p>
    Fórmula:C10H14N6O3
    Pureza:Min. 98 Area-%
    Forma y color:White Powder
    Peso molecular:266.26 g/mol

    Ref: 3D-NA06287

    25g
    368,00€
    50g
    546,00€
    100g
    863,00€
    250g
    1.486,00€
    500g
    2.276,00€
  • (R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine

    CAS:
    <p>(R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine is a nucleoside monophosphate. It has been shown to be an activator of the enzyme adenylate cyclase, which converts ATP into cyclic AMP, a second messenger in cell signaling. (R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine does not have anticancer properties and does not inhibit the production of ribonucleotides or deoxyribonucleotides. This compound is synthesized using novel methods and is of high purity and quality.</p>
    Fórmula:C10H12N5Na3O9P2S
    Pureza:Min. 95%
    Peso molecular:509.21 g/mol

    Ref: 3D-FE168675

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  • 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

    CAS:
    <p>5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.</p>
    Fórmula:C41H49N4O9P
    Pureza:Min. 95%
    Peso molecular:772.82 g/mol

    Ref: 3D-ND163164

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  • 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine

    CAS:
    <p>This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties.<br>2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucle</p>
    Fórmula:C31H31FN2O7
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:562.59 g/mol

    Ref: 3D-ND09140

    1g
    218,00€
    2g
    305,00€
    5g
    456,00€
    10g
    607,00€
    500mg
    170,00€
  • 9-Deazaguanosine

    CAS:
    <p>9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.</p>
    Fórmula:C11H14N4O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:282.25 g/mol

    Ref: 3D-ND06109

    5mg
    187,00€
  • 6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine

    CAS:
    <p>6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine is a nucleoside analog that is used to treat HIV. It is a prodrug that undergoes phosphorylation by host cell kinases to form its active form, 2'-deoxycytidine monophosphate (2'DCPM). This drug has been shown to inhibit the replication of HIV in vitro and in vivo. 6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine has antiviral potency against both group M and N HIV isolates. It also enhances polymerase chain reaction amplification of HIV DNA and can be used in tissue culture experiments to study the effects of drugs on the virus. Clinical trials have shown that 6-amino 9-(2',3'-dideoxy-2</p>
    Fórmula:C10H12FN5O2
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:253.24 g/mol

    Ref: 3D-NA05179

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  • 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine

    CAS:
    <p>Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Pureza:Min. 95%

    Ref: 3D-FD144639

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  • 1-(b-D-Xylofuranosyl)-2-thiouracil

    CAS:
    <p>1-(b-D-Xylofuranosyl)-2-thiouracil is a synthetic nucleoside that inhibits viral and cancer cell growth. It is an analog of the natural nucleoside thymidine, with an extra oxygen atom at position 2. The molecule forms a monophosphate, which is converted to a diphosphate by phosphoramidate synthase. This diphosphate is then incorporated into DNA, where it inhibits the activity of DNA polymerase and deoxyribonucleases, leading to inhibition of DNA synthesis. 1-(b-D-Xylofuranosyl)-2-thiouracil also has antiviral properties as it can inhibit viral replication by blocking the incorporation of nucleotides into the growing DNA strand.</p>
    Fórmula:C9H12N2O5S
    Pureza:Min. 95%
    Peso molecular:260.27 g/mol

    Ref: 3D-NX163071

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