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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3567 productos de "Nucleósidos"

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  • N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt

    CAS:
    <p>N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt is a monophosphate nucleoside that has been modified with a 6-aminohexylaminocarbonyl group. It is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and proteins. N6-[(6-Aminohexyl)carbamoylmethyl]adenosine 5'-triphosphate lithium salt is novel and high quality.</p>
    Fórmula:C18H32N7O14P3·xLi
    Pureza:Min. 95%

    Ref: 3D-NA73270

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  • 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite


    <p>5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a nucleoside which is an activator for DNA synthesis. It is synthesized from the natural substance thymidine, and it can be modified to have various properties by changing the chemical group that attaches to the 3' carbon. 5'-O-tert-Butyldimethylsilylthymidine 3'-CE phosphoramidite is a novel nucleoside that has been shown to be anticancerous in vitro. This compound may also play a role in treating viral infections due to its antiviral properties.</p>
    Fórmula:C25H45N4O6PSi
    Pureza:Min. 95%
    Peso molecular:556.72 g/mol

    Ref: 3D-PB08645

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  • 2-Deoxy-2-fluoro-b-D-arabinofuranosylamine

    CAS:
    <p>2-Deoxy-2-fluoro-b-D-arabinofuranosylamine (2DF) is a monophosphate nucleoside analog that is chemically modified to form 2DF. The 2DF has shown antiviral, anticancer, and anti-inflammatory activities. It inhibits the proliferation of cancer cells by blocking the synthesis of DNA and RNA, which are necessary for cellular reproduction. This drug also has been shown to have an activator effect on diphosphate nucleotide incorporation into DNA.</p>
    Fórmula:C5H10FNO3
    Pureza:Min. 95%
    Peso molecular:151.14 g/mol

    Ref: 3D-ND89208

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  • N-Phenylpyridin-4-amine

    CAS:
    <p>N-Phenylpyridin-4-amine is a tautomeric compound that has been shown to inhibit the growth of cancer cells. It is able to bind to tyrosine kinase and inhibit its activity, which affects the proliferation of cancer cells. N-Phenylpyridin-4-amine also inhibits mitochondrial functions by inhibiting cytochrome c oxidase. This drug also has an anti-inflammatory effect, inhibiting the production of cytokines such as IL1β, IL6, and TNFα. The biological function of N-Phenylpyridin-4-amine is not yet fully understood. It may be due to the inhibition of protein tyrosine phosphatases (such as PTP1B), which are involved in insulin signalling pathways.</p>
    Fórmula:C11H10N2
    Pureza:Min. 95%
    Forma y color:White Off-White Powder
    Peso molecular:170.21 g/mol

    Ref: 3D-NP66702

    5g
    135,00€
  • 2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite

    CAS:
    <p>2'-Deoxy-5'-O-DMT-N2-ethylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue. It is a nucleotide analog with potent antiviral and anticancer activities. This compound has been shown to be an activator of deoxyribonucleosides and ribonucleosides, which may lead to the activation of their respective polymerases. It also has high purity, quality, and stability, as well as being inexpensive. Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form</p>
    Fórmula:C42H52N7O7P
    Pureza:Min. 95%
    Forma y color:Solid
    Peso molecular:797.88 g/mol

    Ref: 3D-PD09212

    10mg
    182,00€
    25mg
    341,00€
    50mg
    486,00€
    100mg
    805,00€
    250mg
    1.355,00€
  • 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine

    CAS:
    <p>1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine is a nucleoside analog with a modified ribofuranosyl sugar, which includes a 2'-O-4'-C-methylene bridge that constrains the sugar conformation.</p>
    Fórmula:C11H14N2O6
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:270.24 g/mol

    Ref: 3D-NM10211

    1g
    1.440,00€
    2g
    2.224,00€
    5g
    4.572,00€
    250mg
    636,00€
    500mg
    1.008,00€
  • 2',3',5'-Tri-O-acetylguanosine

    CAS:
    <p>2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.</p>
    Fórmula:C16H19N5O8
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:409.35 g/mol

    Ref: 3D-NT06136

    25g
    203,00€
    50g
    320,00€
    100g
    502,00€
    250g
    725,00€
    500g
    1.254,00€
  • 3-Iodo-1-(2-C-methyl-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine,

    CAS:
    <p>3-Iodo-1-(2-C-methyl-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a novel antiviral monophosphate nucleotide analog. It has been shown to be an effective activator of the enzyme ribonucleotide reductase, which is involved in DNA synthesis and repair. 3Iodo possesses anticancer activity, inhibiting the proliferation of cancer cells by interfering with DNA synthesis. The compound also inhibits tumor cell growth in vivo by inducing apoptosis. 3Iodo has been shown to inhibit HIV replication and may have potential as a treatment for HIV/AIDS.</p>
    Pureza:Min. 95%

    Ref: 3D-NI14087

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  • 2'-Deoxy-4'-thioadenosine

    CAS:
    <p>2'-Deoxy-4'-thioadenosine is a purine nucleoside that is synthesized from 4-thiouridine and phosphorylase. It is cytotoxic and has significant cytotoxicity against cultured cells. The cytotoxicity of 2'-deoxy-4'-thioadenosine was found to be due to its conversion to the triphosphate form in the cells, which inhibits both DNA synthesis and RNA synthesis. This drug also has an inhibitory effect on the growth of tumor cells by inhibiting ribosomal protein synthesis.</p>
    Fórmula:C10H13N5O2S
    Pureza:Min. 95%
    Peso molecular:267.31 g/mol

    Ref: 3D-ND63590

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  • 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine

    CAS:
    <p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine is a synthetic nucleoside analog that has been shown to be an activator of DNA synthesis in mammalian cells. It has antiviral, anticancer, and antibiotic properties due to its ability to inhibit the growth of a variety of cancer cells. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine also inhibits viral replication by interfering with the replication machinery. This nucleoside analog is a modified form of 6MP and has high purity and quality.</p>
    Pureza:Min. 95%

    Ref: 3D-ND162823

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  • BBQ-650-DT CEP

    CAS:
    <p>BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.</p>
    Fórmula:C76H89N12O15P
    Pureza:Min. 95%
    Peso molecular:1,441.6 g/mol

    Ref: 3D-FLB55446

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  • 5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    CAS:
    <p>5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound that has antiviral and anticancer properties. It is synthesized by the reaction of 5,5'-dibromoimidazole with 4,4'-dimethoxytrityl chloride. This product is used as a building block in the synthesis of deoxyribonucleosides, modified phosphoramidites, and nucleosides. It also has high purity and high quality.</p>
    Pureza:Min. 95%

    Ref: 3D-NB14095

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  • 9-(b-D-Arabinofuranosyl)-8-chloroadenine

    CAS:
    <p>9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.</p>
    Pureza:Min. 95%

    Ref: 3D-NA162973

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  • 2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine


    <p>2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is an antiviral nucleoside that is chemically synthesized from 5-methoxyuridine. It has been shown to inhibit the replication of HIV in cell cultures and animal models. This drug can be used as a phosphoramidite for the synthesis of oligonucleotides.<br> 2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is a novel nucleoside that has not been previously reported in the chemical literature.</p>
    Pureza:Min. 95%

    Ref: 3D-NB163065

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  • 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

    CAS:
    <p>5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.</p>
    Fórmula:C41H49N4O9P
    Pureza:Min. 95%
    Peso molecular:772.82 g/mol

    Ref: 3D-ND163164

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  • 2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine

    CAS:
    <p>2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine (2'AAZ) is a modified nucleoside that has antiviral and anticancer activities. This compound blocks the synthesis of DNA, RNA, and proteins. 2'AAZ inhibits cell proliferation by interfering with the replication of DNA and by inhibiting protein synthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The IC50 values for 2'AAZ are 5 μM for herpes simplex virus type 1 (HSV1) infection in Vero cells, 4 μM for HSV2 infection in Vero cells, 3 μM for influenza A virus (H1N1) infection in MDCK cells, and 0.5 μM for human immunodeficiency virus type 1 (HIV-1) infection in CEM-SS cells.</p>
    Pureza:Min. 95%

    Ref: 3D-NA144623

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  • N4-Methylcytidine 5'-triphosphate triethylammonium salt


    <p>N4-Methylcytidine 5'-triphosphate triethylammonium salt is a novel nucleoside analog that inhibits the growth of tumor cells. It is synthesized by reacting N4-methylcytidine with phosphoramidite in an amine base, and then treated with triethylamine to produce a triethylammonium salt. This nucleoside analog inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The resulting monophosphate compound has been shown to be effective in cancer treatment and may also be used as an antiviral agent.</p>
    Fórmula:C10H18N3O14P3
    Pureza:Min. 95%
    Peso molecular:497.18 g/mol

    Ref: 3D-NM71657

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  • Palmitoyl coenzyme A potassium salt

    CAS:
    <p>Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.</p>
    Fórmula:C37H65N7O17P3SK
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:1,044.03 g/mol

    Ref: 3D-NP46059

    1mg
    211,00€
    2mg
    291,00€
    5mg
    444,00€
  • 5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution

    CAS:
    <p>5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.</p>
    Fórmula:C10H18N3O14P3·xNa
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:497.18 g/mol

    Ref: 3D-NM11441

    1mg
    670,00€
    2mg
    949,00€
    5mg
    2.030,00€
    10mg
    3.793,00€
  • N6-Benzoyl-2’-chloro-2’-deoxy-5’-O-DMT-adenosine


    <p>N6-Benzoyl-2’-chloro-2’-deoxy-5’-O-DMT-adenosine is a novel nucleoside that has been shown to have anti-cancer, antiviral, and antiinflammatory activities. It is structurally related to 2’,3’,5’triphosphate adenine (TPAD) and inhibits the synthesis of DNA by competitive inhibition of ribonucleotide reductase. TPAD also induces apoptosis in tumor cells. N6BzCdA has an IC50 value of 0.5 μM for TPAD synthetase from Escherichia coli and rat liver, indicating that it is a potent inhibitor of this enzyme. The purity level of this product is greater than 98%, with a CAS number of 67972-83-1.</p>
    Pureza:Min. 95%

    Ref: 3D-NB162967

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