Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3570 productos de "Nucleósidos"
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6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H pyrazolo[3,4 d]pyrimidine can be used in the synthesis of phosphoramidites for DNA synthesis and for the production of monophosphate nucleotides. The compound has been shown to inhibit the growth of cells in culture that are resistant to other antiinfectives such as erythromycin and chloramphenicol.Pureza:Min. 95%Adenosine
CAS:Endogenous adenosine receptor ligand; regulator of innate immunityFórmula:C10H13N5O4Pureza:(Titration) 99.0 To 101.0%Forma y color:White PowderPeso molecular:267.25 g/mol2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine
CAS:2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine is an analogue of 5-hydroxymethyluridine. The 2’,3’,5’-tri-O-benzoyl group is used to protect the hydroxyl group and prevent oxidation. It has been shown to inhibit replication of DNA in vitro and in vivo against human leukemia cells. This product is synthesized by phosphoramidite chemistry from 2′,3′,5′triphosphate and 5′hydroxymethyluridine. The purity of this product is >99%. 2’,3’,5’-Tri-O-benzoyl-5-(hydroxymethyl)uridine can be used as a nucleoside or nucleotide analog for anticancer treatments or other therapeutic purposes.Pureza:Min. 95%5-Fluoro-4’-C-methyluridine
CAS:5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.Pureza:Min. 95%Isocytidine triphosphate triethylamine
CAS:Isocytidine triphosphate triethylamine salt is a nucleoside that has been modified to include an amino group. It is a monophosphate, which means it contains one phosphate group. Isocytidine triphosphate triethylamine salt has shown anticancer properties as it inhibits the synthesis of DNA and RNA. This compound also prevents the activation of transcription factors, such as NF-κB, that are important in cancer cell proliferation.Fórmula:C9H16N3O14P3•(C6H15N)xPureza:Min. 95%Forma y color:PowderPeso molecular:483.15 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS:Intermediate in the synthesis of nelarabineFórmula:C10H12ClN5O4Pureza:Min. 97 Area-%Forma y color:Off-White PowderPeso molecular:301.69 g/mol5'-O-MMT-thymidine 3'-CE phosphoramidite
CAS:5'-O-MMT-thymidine 3'-CE phosphoramidite is a novel anticancer drug that is modified from the natural nucleoside thymidine. It has been shown to inhibit the activity of DNA polymerase, preventing DNA synthesis and replication. It also inhibits viral DNA replication, including HIV and herpes simplex virus type-1 (HSV-1). 5'-O-MMT-thymidine 3'-CE phosphoramidite has antiviral properties against HIV and HSV-1. This nucleoside is synthesized by reacting 5'-O-methyl cytidylic acid with an activated phosphite in the presence of triethylamine in dichloromethane. The product is purified by column chromatography on silica gel and recrystallization from acetonitrile.
Fórmula:C39H47N4O7PPureza:Min. 95%Peso molecular:714.81 g/mol2'-Amino-2'-deoxyguanosine
CAS:2'-Amino-2'-deoxyguanosine is a modified nucleoside, based on guanosine. The 2'-hydroxyl has been replaced by an amino group, which can form different hydrogen bonds compared to a hydroxyl or just a hydrogen, altering the way the sugar interacts in a DNA or RNA strand.Fórmula:C10H14N6O4Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:282.26 g/molN2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel ribonucleotide with high purity and high quality. It is an activator of DNA synthesis and can be used in the synthesis of DNA, monophosphate, and diphosphate. N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is used for the preparation of anticancer drugs, antiviral agents, and other nucleosides.Fórmula:C44H55N8O8PPureza:Min. 95%Forma y color:White PowderPeso molecular:854.95 g/mol3’-b-C-Methyluridine
CAS:3’-b-C-Methyluridine (3′-b-CMU) is an analog of uridine. It inhibits the activity of viral and bacterial nucleases by attacking the phosphate group. 3′-b-CMU inhibits syncytial formation in cell cultures, which may be due to its ability to inhibit RNA synthesis. This drug has a hydroxyl group that can react with free radicals and may have some inhibitory effect on deoxyribonucleoside triphosphate hydrolysis. 3′-b-CMU is not widely used clinically because it is not readily available, but it is being reinvestigated for use in corynebacterium infections.
Pureza:Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside that contains a fluorinated sugar moiety and a thymine base, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl of the sugar.Fórmula:C31H31FN2O7Pureza:Min. 95%Peso molecular:562.6 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.
Fórmula:C44H49N5O7SiPureza:Min. 97 Area-%Forma y color:PowderPeso molecular:787.97 g/mol3’-b-Amino-2’,3-dideoxy uridine
CAS:3’-b-Amino-2’,3-dideoxy uridine is an activator nucleoside that is a novel therapeutic agent for viral infections and cancer. It has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), as well as anticancer activity against human breast adenocarcinoma cells. 3’-b-Amino-2’,3-dideoxy uridine is a modified nucleoside with antiviral and anticancer properties. This drug has been shown to inhibit HSV-1 replication by interfering with the synthesis of viral DNA. 3’-b-Amino-2’,3-dideoxy uridine also inhibits the proliferation of human breast adenocarcinoma cells by inhibiting ribonucleotide reductase.Fórmula:C9H13N3O4Pureza:Min. 95%Peso molecular:227.22 g/mol5'-Azido-5'-deoxy-2'-O-methyluridine
CAS:5'-Azido-5'-deoxy-2'-O-methyluridine is a nucleoside that is a modified version of 2'-deoxyuridine. It is synthesized from uridine, which is converted to 5'-azidouridine via the action of azidase. 5'-Azido-5'-deoxy-2'-O-methyluridine has antiviral activity and can be used as an activator of DNA polymerases. The monophosphate form of this compound can be phosphoramidated to give the corresponding diphosphates, which are used in DNA synthesis to produce double stranded DNA.Fórmula:C10H13N5O5Pureza:Min. 95%Peso molecular:283.24 g/molN6-Benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine
The N6-benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that is a potent inhibitor of the human immunodeficiency virus type 1 (HIV-1) and has been shown to be effective against cancer. It is a phosphoramidite nucleoside with high purity and high quality, which can be used as an antiviral agent or an anticancer agent. The chemical name for this compound is 2'-(N6-Benzoyl)-2'-deoxyadenosine 5'-O-(DMT). This product is also known as NBDT, and it has been modified by changing the ribose sugar to DMT. NBDT inhibits viral replication by preventing the formation of DNA from RNA in the reverse transcription process. This process requires two enzymes: HIV reverse transcriptase and DNA polymerase α. The first enzyme, HIV reverse transcriptase,Pureza:Min. 95%3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine
CAS:Please enquire for more information about 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%1-(Arabinofuranosyl)-5-azidomethyluracil
CAS:1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.Pureza:Min. 95%9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine
9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.Pureza:Min. 95%S-Adenosylmethione-1,4-butanedisulfonate
CAS:S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.Fórmula:C42H74N12O28S8Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:1,451.63 g/mol1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide
1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide is a phosphoramidite that is used for the synthesis of DNA and RNA. It has antiviral and anticancer properties. This compound binds to DNA and inhibits the activity of topoisomerase II, which leads to cell death by inhibiting the production of proteins vital for cell division. 1-(2,3,5-Tri-O-acetyl-b-D-ribofuranosyl)nicotinamide also prevents the replication of viral RNA by inhibiting reverse transcriptase.Fórmula:C17H21N2O8Pureza:Min. 95%Peso molecular:381.36 g/mol
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