Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate
CAS:3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.Fórmula:C13H22N3O14P3Pureza:Min. 95%Peso molecular:537.25 g/mol5-Azacytidine
CAS:An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.
Fórmula:C8H12N4O5Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:244.21 g/mol2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite
CAS:2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br>br>2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotidesFórmula:C42H51N8O5PPureza:Min. 95%Peso molecular:778.9 g/molN2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
CAS:N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is an organic compound that has been modified to be an anticancer agent. It has been shown to have antiviral and antiparasitic activities. N2-Acetyl-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog, which means it substitutes for the natural ribonucleoside in DNA or RNA. The modified nucleotide prevents the incorporation of the normal nucleotide into DNA or RNA, thereby inhibiting replication. This compound also inhibits tumor growth by interfering with viral replication and inhibiting tumor angiogenesis.Fórmula:C43H52N7O9PPureza:Min. 95%Peso molecular:841.89 g/mol2'-Deoxy-6-thioguanosine-5'-monophosphate
CAS:Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.Fórmula:C10H14N5O6PSPureza:Min. 95%Peso molecular:363.29 g/mol4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-β-D- ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic activator that selectively activates the transcription of genes in cells. It has been shown to have anticancer activity and may be useful as a therapeutic agent for the treatment of certain cancers. 4C 7 (2dEB 3,5BT) 5I is also known to be an antiviral agent against HIV and influenza virus. The modification on the 2'-deoxyribose sugar moiety can enhance both activation and antiviral activities.Pureza:Min. 95%5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite
Producto controlado5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite is an activator for DNA synthesis and is used in the synthesis of deoxyribonucleosides as antiviral and anticancer agents. It is a modified nucleotide, which has been synthesized from thymidine. This product has shown to be effective in the treatment of cancer cells in vitro.Fórmula:C26H32N4O7PD3Pureza:Min. 95%Peso molecular:549.58 g/mol5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt
CAS:5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.Fórmula:C9H12BrN2O8PNa2Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:433.06 g/mol2',3'-Dideoxyinosine
CAS:2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversionFórmula:C10H12N4O3Pureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:236.23 g/molAdenosine 5'-monophosphate monohydrate
CAS:Adenosine 5'-monophosphate monohydrate (AMP) is a nucleotide that is released by cells in response to various stimuli. It is involved in the regulation of metabolic rate, cell death, and inflammatory responses. AMP may also act as a mediator of opioid-induced analgesia. AMP has been shown to inhibit the production of pro-inflammatory cytokines in activated macrophages and to reduce nociception at high doses. This drug also has an effect on blood pressure and may be used for the treatment of hypertension.Fórmula:C10H14N5O7P•H2OPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:365.24 g/molb-Nicotinamide adenine dinucleotide phosphate sodium salt
CAS:Coenzyme and regenerating electron donor in catabolic processesFórmula:C21H27N7NaO17P3Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:765.39 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine is a versatile nucleoside building block.
Fórmula:C38H35N5O6Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:657.72 g/mol2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine (2DFO) is a novel nucleoside analog that is phosphorylated to 2DFP, which is an antiviral drug that has been shown to inhibit the replication of HIV. 2DFO inhibits the activity of DNA polymerase, RNA polymerase, and reverse transcriptase, preventing the synthesis of viral DNA and RNA. This drug also inhibits the activity of human topoisomerase II alpha and beta, which are enzymes involved in replication and transcription. 2DFO binds to purine nucleosides by competitive inhibition at the enzyme active site, preventing the formation of ribonucleotides from deoxyribonucleosides.Pureza:Min. 95%Adenosine
CAS:Endogenous adenosine receptor ligand; regulator of innate immunityFórmula:C10H13N5O4Pureza:(Titration) 99.0 To 101.0%Forma y color:White PowderPeso molecular:267.25 g/molAcetyl hypoxanthine
CAS:Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.Fórmula:C7H6N4O2Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:178.15 g/mol8-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.Fórmula:C10H13N5O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:283.25 g/mol5'-O-p-Anisoyl-2'-deoxyuridine
5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.Fórmula:C17H18N2O7Pureza:Min. 95%Peso molecular:362.33 g/molN6-Benzyladenosine 5'-monophosphate sodium salt monohydrate
CAS:N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.
Fórmula:C17H18N5Na2O7P·H2OPureza:Min. 97 Area-%Forma y color:PowderPeso molecular:499.32 g/mol3'-Amino-3'-deoxy-D3-thymidine
Producto controlado3'-Amino-3'-deoxy-D3-thymidine is a novel, modified nucleoside of the deoxyribonucleosides group. It is an activator of ribonucleotide reductase and has antiviral properties. 3'-Amino-3'-deoxy-D3-thymidine is an anticancer agent that induces DNA synthesis and inhibits RNA synthesis.Fórmula:C10H12N3O4D3Pureza:Min. 95%Peso molecular:244.27 g/mol5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine
CAS:5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.Fórmula:C11H11N2O5Pureza:Min. 95%Peso molecular:251.22 g/mol
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