Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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2’-Deoxy-N4-dimethylcytidine
CAS:2’-Deoxy-N4-dimethylcytidine is a synthetic nucleoside analog that is used to inhibit viral replication in the treatment of AIDS and cancer. It is phosphorylated by adenosine kinase to form deoxydimethylcytidine monophosphate (dDMP), which inhibits viral DNA synthesis by inhibiting the activity of reverse transcriptase, an enzyme involved in the production of viral DNA. 2’-Deoxy-N4-dimethylcytidine has also been shown to inhibit cancer cell growth by interrupting mitosis and inducing apoptosis.Pureza:Min. 95%7-Deaza-2'-deoxy-7-iodoadenosine
CAS:7-Deaza-2'-deoxy-7-iodoadenosine (7DADI) is a modified nucleoside that has antiviral and anticancer properties. It is synthesized by the reaction of 2'-deoxyadenosine with iodine in the presence of an activator such as sodium hypochlorite. 7DADI binds to ribonucleosides, forming a phosphoramidate bond at the 3' position, which leads to inhibition of viral RNA synthesis and DNA replication. This drug also inhibits the growth of cancer cells by inhibiting DNA synthesis and protein synthesis. 7DADI is novel because it is not found in nature or produced by any other organism.
Fórmula:C11H13IN4O3Pureza:Min. 98 Area-%Peso molecular:376.16 g/mol2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.Fórmula:C11H19N2O15P3Pureza:Min. 95%Peso molecular:512.19 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Fórmula:C8H15N4O14P3·Na4Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:576.1 g/mol3'-O-Methyladenosine
CAS:3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.
Fórmula:C11H15N5O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:281.27 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine
CAS:2'-O-(2-Methoxyethyl)-5-methyluridine is a uridine nucleoside that has been prepared by the reaction of amidite with 5-methyluridine. 2'-O-(2-Methoxyethyl)-5-methyluridine is an important intermediate in the synthesis of oligonucleotides, which are synthesized from phosphoramidites. The phenyl group on the amido group is a reactive group that reacts with other functional groups to form an oligonucleotide. 2'-O-(2-Methoxyethyl)-5-methyluridine has a high yield and can be used as a reagent for organic chemistry.Fórmula:C13H20N2O7Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:316.31 g/mol2-Azidoadenosine
CAS:2-Azidoadenosine is a nucleoside analog of adenosine, where the 2'-hydroxyl group of the ribose sugar is replaced with an azido group (–N₃). This substitution imparts unique chemical properties, notably enabling molecules to undergo bioorthogonal reactions, such as click chemistry, which involves the cycloaddition of the azide group with alkynes.
Fórmula:C10H12H8O4Pureza:Min. 95%Forma y color:PowderPeso molecular:308.25 g/molN4-Acetyl-2'-deoxy-5-methylcytidine
N4-Acetyl-2'-deoxy-5-methylcytidine is a novel nucleoside analog of cytidine. It has been shown to be an activator of the immune system, and has antiviral and anticancer properties. This synthetic nucleoside is phosphorylated by kinases in cells to form N4-acetyl-2'-deoxy-5'-methyluridine monophosphate. The phosphate group can be removed by phosphatases in cells to yield N4-acetyl-2'-deoxycytidine, which is a precursor for DNA synthesis.
Fórmula:C12H17N3O5Pureza:Min. 95%Forma y color:PowderPeso molecular:283.28 g/mol5-o-(Dimethoxytrityl)-N4-dimethylaminomethylidene-5-iodo-2'-deoxycytidine
CAS:Dimethoxytrityl-5-iodo-2'-deoxycytidine is a novel, modified nucleoside that has anticancer and antiviral properties. It is synthesized by reacting 5-iodo-2'-deoxycytidine with dimethoxytrityl chloride in the presence of triethylamine. This compound can be used to synthesize oligonucleotide phosphoramidites, ribonucleosides, and diphosphates.Fórmula:C33H35IN4O6Pureza:Min. 95%Peso molecular:710.6 g/mol3'-O-DMT-thymidine 3'-succinyl CPG 500 Å
3'-O-DMT-thymidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis and antiviral agent. It is a modified nucleoside that can be incorporated into DNA. This product is also used as a monophosphate in the synthesis of deoxyribonucleosides, which are used in the manufacture of DNA. 3'-O-DMT-thymidine 3'-succinyl CPG 500 Å has been shown to have antiviral properties against influenza and herpes simplex virus type 1 (HSV1). The anticancer activity of this product may be due to its ability to inhibit DNA replication and RNA transcription by binding to DNA polymerase and RNA polymerase, respectively.Pureza:Min. 95%5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite
5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite is an activator of DNA synthesis. It has antiviral and anticancer properties, which have been shown in animal models. This compound is a novel nucleoside phosphoramidite that can be used to synthesize oligonucleotides. The CAS number for this product is 98469-45-7.Fórmula:C26H35N6O5PPureza:Min. 95%Peso molecular:542.58 g/mol2'-O-Methyladenosine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:2'-O-Methyladenosine-5'-triphosphate sodium salt is a novel nucleoside phosphoramidite. It is an activator and it can be used in the synthesis of DNA and RNA. The compound has antiviral properties and has been shown to inhibit DNA replication, protein synthesis, and RNA transcription. The compound also inhibits the growth of cancer cells by inducing apoptosis.Fórmula:C11H18N5O13P3·xNaPureza:Min. 95%Forma y color:PowderPeso molecular:521.21 g/mol1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil
CAS:1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.Pureza:Min. 95%2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.Pureza:Min. 95%2'-Deoxy-6-thioguanosine
CAS:2'-Deoxy-6-thioguanosine is a purine nucleoside analog that inhibits the activation of transcription factors such as nuclear factor kappa-B (NF-κB) and activator protein 1 (AP-1). It also inhibits the synthesis of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. The matrix effect is an important factor in the prevention of tumor progression. 2'-Deoxy-6-thioguanosine has been shown to inhibit cell proliferation and induce apoptosis in squamous cell carcinoma cells by modulating the expression of HLA class II molecules on tumors. It also prevents invasion by blocking matrix metalloproteinase activity. 2'-Deoxy-6-thioguanosine has been found to be effective against bowel diseases such as ulcerative colitis and Crohn's disease, as well as infectious diseases such as HIV/AIDS.Fórmula:C10H13N5O3SPureza:Min. 97 Area-%Forma y color:PowderPeso molecular:283.31 g/mol6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.Pureza:Min. 95%5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.Fórmula:C39H47N4O9PPureza:Min. 95%Peso molecular:746.79 g/mol3'-O-Aminoacetoxy-2'-deoxyadenosine
amino functionalised nucleosideFórmula:C13H22N6O3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:310.36 g/mol1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.Pureza:Min. 95%6-O-Methylinosine
CAS:6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Fórmula:C11H14N4O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:282.25 g/mol
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