Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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3'-O-Acetylthymidine
CAS:3'-O-Acetylthymidine is a dinucleoside analogue of thymidine. It has been used as a model for human immunodeficiency virus (HIV) and has been shown to be resistant to HIV infection in vitro. 3'-O-Acetylthymidine inhibits the synthesis of protein by binding to the ribosomal RNA of the host cell, preventing the formation of an aminoacyl-tRNA synthetase complex with tRNA. This prevents the incorporation of amino acids into proteins, leading to inhibition of protein synthesis and cell death. 3'-O-Acetylthymidine also inhibits HIV replication by competing with deoxycytidine triphosphate for incorporation into DNA, preventing the synthesis of viral DNA. 3'-O-Acetylthymidine is hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductaseFórmula:C12H16N2O6Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:284.27 g/mol2’C-Methyl-5-methoxyuridine
CAS:2’-C-Methyl-5-methoxyuridine is a nucleoside analog that inhibits viral replication by inhibiting DNA synthesis. It is also used in the treatment of cancer, as it inhibits the growth of tumor cells by altering their genetic material. This drug is a phosphorothioate and can be activated with an activator to form its active form, which is incorporated into DNA during replication. 2’-C-Methyl-5-methoxyuridine has been shown to be effective against many viruses, including human immunodeficiency virus (HIV), herpes simplex virus type 1 (HSV1), and herpes simplex virus type 2 (HSV2). This drug has been shown to cause death of tumor cells via apoptosis or cell cycle arrest at the G0/G1 phase.
Pureza:Min. 95%3'-Amino-3'-deoxy-D3-thymidine
Producto controlado3'-Amino-3'-deoxy-D3-thymidine is a novel, modified nucleoside of the deoxyribonucleosides group. It is an activator of ribonucleotide reductase and has antiviral properties. 3'-Amino-3'-deoxy-D3-thymidine is an anticancer agent that induces DNA synthesis and inhibits RNA synthesis.Fórmula:C10H12N3O4D3Pureza:Min. 95%Peso molecular:244.27 g/mol2'-Deoxy-5-hydroxyuridine
CAS:2'-Deoxy-5-hydroxyuridine is a hydrated form of uracil that is used in the synthesis of nucleic acids. It is also a substrate for DNA polymerases and has been shown to inhibit the replication of herpes simplex virus. 2'-Deoxy-5-hydroxyuridine has been shown to have biological properties, such as inhibition of radiation-induced transformation, inhibition of cancer cell growth, and antiviral activity. The mechanism by which 2'-deoxy-5-hydroxyuridine inhibits the replication of herpes simplex virus is unclear but may be due to its ability to inhibit cellular metabolism.Fórmula:C9H12N2O6Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:244.21 g/mol9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine
CAS:9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine is a novel and high quality antiviral monophosphate deoxyribonucleoside. It is synthesized from 2'-deoxyadenosine monophosphate, 2'-deoxycytidine monophosphate, and 6-chloropurine by the phosphorylation of nucleosides with a modified phosphoramidite method. The polymerase chain reaction (PCR) amplification of HIV DNA was inhibited with this compound in vitro. This drug also has anticancer activity when it is used in combination with other chemotherapeutic drugs such as gemcitabine, cisplatin, and paclitaxel.Pureza:Min. 95%N4-Acetyl-5'-O-DMT-cytidine
CAS:N4-Acetyl-5'-O-DMT-cytidine is an antiviral drug that inhibits the viral DNA polymerase. It is a modified nucleoside, which is activated by phosphorylation. N4-Acetyl-5'-O-DMT-cytidine is used in research for its anticancer properties and has shown to inhibit the growth of cancer cells in vitro. The compound was found to be more potent than cytidine and other modified nucleosides.Fórmula:C32H33N3O8Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:587.63 g/mol1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil
1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil is a synthetic nucleoside and a phosphoramidite. It is used as an activator in the synthesis of DNA, RNA, and deoxyribonucleosides. 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)uracil has antiviral and anticancer effects. It can be used to modify DNA and inhibit cancer cell proliferation. This product is high quality, novel, and high purity.
Pureza:Min. 95%2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine
2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine is a novel nucleoside analog that belongs to the group of cytidine analogs. It has antiviral activity, which is due to its ability to inhibit viral replication by disrupting the synthesis of viral RNA. This drug is an activator and can be used for cancer treatment. 2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine binds to ribonucleosides and deoxyribonucleosides, preventing their incorporation into DNA or RNA. It also inhibits the biosynthesis of RNA and DNA, which leads to cell death in tumor cells.Pureza:Min. 95%7-Iodo-7-deaza-2'-C-methylguanosine
7-Iodo-7-deaza-2'-C-methylguanosine has antiviral activity and is used as a building block in the synthesis of DNA and RNA molecules. 7-Iodo-7-deaza-2'-C-methylguanosine is a novel synthetic nucleoside that has anticancer properties and is used for the treatment of different types of cancer. It is also used for the prevention of viral infections, such as influenza. This product has high purity and is available in its phosphate or monophosphate form.Pureza:Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a modified nucleoside analogue with anticancer activity. It is synthesized by reacting 2'-deoxy-N2-isobutyryl-5'-O-methylguanosine with diethyl chlorophosphate in the presence of tetrazole. This novel compound has been shown to have antiviral and antitumor activities as well as high affinity for DNA and RNA.Fórmula:C43H52N7O7PPureza:Min. 95%Peso molecular:809.91 g/mol3'-O-Methylguanosine
CAS:3'-O-Methylguanosine is a nucleoside that is found in the guanine molecule and has been shown to have inhibitory properties against malignant brain tumors. 3'-O-Methylguanosine blocks the synthesis of DNA, RNA, and peptide hormones. It also inhibits the growth of erythromycin-resistant strains of bacteria. The kinetic data for 3'-O-Methylguanosine was obtained from experiments with leukemic mice and carcinoma cell lines. The enzyme glut1 regulates the rate of metabolism of 3'-O-Methylguanosine. It is metabolized by dehydroascorbic acid reductase to 3'-deoxyadenosine monophosphate (dAMP) and then to adenosine monophosphate (AMP). The optimum pH for this reaction is 7.3 at 37 degrees Celsius.Fórmula:C11H15N5O5Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:297.27 g/molThymidine 3'-O-L-valinyl ester
Thymidine 3'-O-L-valinyl ester is a monophosphate nucleoside with antiviral, anticancer, and antimalarial activities. It has been shown to be an effective inhibitor of HIV-1 replication in vitro, and also inhibits the growth of human cancer cell lines. Thymidine 3'-O-L-valinyl ester is a novel compound that has phosphoramidite synthesis and chemical modifications to improve its stability and cytotoxicity. It can be used as a building block for DNA synthesis, with high purity and quality.Pureza:Min. 95%8-Chloroadenosine-5'-monophosphate triethylammonium, about 28 mg/ml aqueous solution
CAS:8-Chloroadenosine-5'-monophosphate triethylammonium is a novel phosphoramidite that is used in the synthesis of DNA. 8-Chloroadenosine-5'-monophosphate triethylammonium has been shown to activate antiviral and anticancer drugs with high specificity. It is also used as a reagent for the synthesis of deoxyribonucleosides and nucleosides. 8-Chloroadenosine-5'-monophosphate triethylammonium has high purity and can be used in the synthesis of DNA, RNA, and other nucleosides.Fórmula:C10H13ClN5O7P•(C6H15N)2Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:584.05 g/mol5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite
Producto controlado5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite is an activator for DNA synthesis and is used in the synthesis of deoxyribonucleosides as antiviral and anticancer agents. It is a modified nucleotide, which has been synthesized from thymidine. This product has shown to be effective in the treatment of cancer cells in vitro.Fórmula:C26H32N4O7PD3Pureza:Min. 95%Peso molecular:549.58 g/molMizoribine
CAS:Inhibitor of heat shock protein Hsp60; immunosuppressant
Fórmula:C9H13N3O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:259.22 g/molb-Nicotinamide adenine dinucleotide reduced form, disodium salt
CAS:β-Nicotinamide adenine dinucleotide reduced form, most commonly known as NADH, is a cofactor involved in the electron transport chain, in the metabolism of amino acids and many other cellular processes such as the synthesis of ATP. It is also a substrate for glutathione peroxidase and superoxide dismutase. The reduced form of NADH can be used as an indicator for glutathione peroxidase activity. In addition, it has been shown to have antioxidant properties by reducing reactive oxygen species (ROS) and inhibiting lipid peroxidation. This product has been used in formulations of synthetic drugs for the treatment of women with long-term effects of menopause, such as osteoporosis and cardiovascular disease. It has also been used in the production of alginate gel, which can be used to create scaffolds for tissue engineering applications. More recently, in bioorganic chemistry, NADH has been used as a source of hydride species for reduction reactions.
Fórmula:C21H27N7O14P2·2NaPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:709.4 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Fórmula:C38H37N3O8Pureza:Min. 95%Forma y color:PowderPeso molecular:663.72 g/molb-Nicotinamide adenine dinucleotide phosphate sodium salt
CAS:Coenzyme and regenerating electron donor in catabolic processesFórmula:C21H27N7NaO17P3Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:765.39 g/mol5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine
CAS:5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine is a novel nucleoside analogue that is an activator of the innate immune system. It is used for the treatment of cancer and viral infections. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has been shown to have anticancer activity against pancreatic, lung, breast, prostate, colon, and leukemia cells in vitro. This drug also inhibits influenza virus A/WSN/33 replication in cell culture by blocking the RNA polymerase complex at the initiation stage. 5'-O-Acetyl-2',3'-dideoxy-3'-fluoro-a-uridine has also been shown to be active against herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1).Pureza:Min. 95%Guanosine 5'-diphosphate disodium salt
CAS:Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside dipsphate and a pyruvate kinase substrate, which converts GDP to GTP.Fórmula:C10H13N5Na2O11P2Pureza:Min. 90.0 Area-%Peso molecular:487.16 g/mol
