Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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S-Adenosyl-L-methionine disulfate tosylate
CAS:S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.Fórmula:C22H34N6O16S4Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:766.8 g/mol5-(2-Hydroxyethyl)uridine
CAS:5-(2-Hydroxyethyl)uridine (5HUdR) is a nucleoside that is structurally related to uridine. 5HUdR has been used as an analogue of uridine and has been shown to be catalytically hydrogenated with acrylonitrile in the presence of a palladium catalyst. 5HUdR can also be synthesized by photochemical hydrogenation with trimethylsilyl derivatives. This compound is a functional group in the synthesis of 2-deoxyuridine, which is an important precursor for DNA synthesis.Fórmula:C11H16N2O7Pureza:90%MinForma y color:PowderPeso molecular:288.25 g/molN6-Benzoyl-5'-O-DMT-N3-methyladenosine
N6-Benzoyl-5'-O-DMT-N3-methyladenosine is a modified nucleotide. It has antiviral, anticancer and antitumor properties. N6-Benzoyl-5'-O-DMT-N3-methyladenosine is an activator of the phosphodiesterase enzyme that hydrolyzes cAMP. This compound can be used as a potential therapeutic agent for treating leukemia and other cancers.Fórmula:C39H39N5O7Pureza:Min. 95%Peso molecular:689.77 g/mol9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine
9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine is a novel antiviral that belongs to the class of deoxyribonucleosides. It is synthesized by reacting 5’-methyl-2,4(1H,3H) pyrimidinedione with 6-chloropurine in the presence of sodium bicarbonate and sulfuric acid. 9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine inhibits DNA synthesis by binding to the enzyme ribonuclease H (RNase H). RNase H hydrolyzes RNA sequences that are complementary to the 3’ end of DNA sequences and this drug prevents RNase H from functioning. 9-(5’-Methyl-b-Dribofuranosyl)-6 chloropurine also inhibits tumour cells and has shown anticancer activity inPureza:Min. 95%N6-Methyl-2'-C-methyladenosine
CAS:N6-Methyl-2'-C-methyladenosine is a modified nucleoside that belongs to the category of Deoxyribonucleosides. It is a novel compound with antiviral, anticancer, and antitumor properties. N6-Methyl-2'-C-methyladenosine inhibits viral replication by blocking the synthesis of DNA. This compound also has antiproliferative effects on cancer cells and retards tumor growth in animal models. N6-Methyl-2'-C-methyladenosine is synthesized from phosphoramidites in a two step process: first, the addition of methyl iodide to the phosphorus atom followed by nucleophilic substitution with methylamine.Fórmula:C12H17N5O4Pureza:Min. 95%Peso molecular:295.29 g/mol2'-Azido-2'-deoxycytidine
CAS:2'-Azido-2'-deoxycytidine is a nucleoside analog derived from cytidine, in which the 2'-hydroxyl group of the ribose is replaced by an azido group (–N₃), while the cytosine base and remaining sugar structure are preserved. This substitution imparts the molecule with bioorthogonal reactivity, enabling its use in chemical biology applications such as nucleic acid labeling via azide-alkyne "click" chemistry. The azido group also sterically and electronically alters sugar conformation and enzymatic recognition, which can affect its incorporation into DNA or RNA by polymerases. Consequently, 2'-azido-2'-deoxycytidine is a useful research tool.
Fórmula:C9H12N6O4Pureza:Min. 95 Area-%Forma y color:Slightly Yellow PowderPeso molecular:268.2 g/molS-(4-Nitrobenzyl)-6-thioinosine
CAS:S-(4-Nitrobenzyl)-6-thioinosine (SBT) is a nucleoside with biochemical properties that are similar to those of adenosine. SBT is an equilibrative nucleoside, which means that it can bind to both DNA and RNA. It has been shown to be effective in inhibiting the growth of cancer cells in vitro by binding to DNA. SBT binds to the purine nucleotide transporter and prevents the uptake of uridine, adenosine, and other nucleosides into the cell. This process leads to a decrease in intracellular concentrations of these nucleosides. SBT also binds to divalent metal ions such as copper or zinc, which may affect its activity on cancer cells.Fórmula:C17H17N5O6SPureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:419.41 g/mol10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite
CAS:10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.Fórmula:C46H82N3O7PPureza:(31P-Nmr) Min. 95 Area-%Forma y color:Colorless PowderPeso molecular:820.13 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside analog, which has potent antiviral activity against HIV and other retroviruses. It is synthesized from 5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine by the reaction of sodium bicarbonate with 2',3'-dideoxyadenosine in the presence of an activator. The product can be used for the synthesis of RNA or DNA for use as probes, primers, and templates in polymerase chain reactions (PCRs).Fórmula:C44H53FN7O8PPureza:Min. 95%Forma y color:White PowderPeso molecular:857.91 g/mol2'-Deoxy-2'-fluoroinosine
CAS:2'-Deoxy-2'-fluoroinosine is a modified nucleoside analog derived from inosine, where the 2' hydroxyl group of the sugar (normally present in ribonucleosides) is replaced with a fluorine atom, and the molecule contains a deoxyribose sugar.Fórmula:C10H11FN4O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:270.22 g/mol3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine
Producto controlado3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine is a novel modified nucleoside that has antiviral and anticancer properties. It is an activator of the DNA polymerase, ribonucleotide reductase, and thymidine kinase enzymes. 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine has been shown to inhibit the growth of human cancer cells in vitro and in vivo.Fórmula:C18H18N3O7D3Pureza:Min. 95%Peso molecular:394.39 g/mol7-Methylguanosine 5'-triphosphate sodium
CAS:7-Methylguanosine 5'-triphosphate sodium salt is a Novel, High purity, Activator, High quality, Modified, Ribonucleosides. CAS No. 104809-18-9. Synthetic, DNA, Phosphoramidites. Anticancer, diphosphate. 7-Methylguanosine 5'-triphosphate sodium salt is an antiviral agent that blocks the synthesis of viral RNA or DNA by inhibiting the enzyme ribonucleotide reductase. It is a monophosphate analog of guanosine triphosphate and may be useful in the treatment of cancer or antiviral therapy because it inhibits cell proliferation and induces apoptosis in tumor cells.Fórmula:C11H18N5O14P3•NaxPureza:Min. 85 Area-%Forma y color:PowderPeso molecular:537.21 g/mol8-Bromo-2'-deoxyguanosine
CAS:8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.Fórmula:C10H12BrN5O4Pureza:Min. 90 Area-%Forma y color:Off-White PowderPeso molecular:346.14 g/mol5'-Azido-5'-deoxy-2'-O-methyluridine
CAS:5'-Azido-5'-deoxy-2'-O-methyluridine is a nucleoside that is a modified version of 2'-deoxyuridine. It is synthesized from uridine, which is converted to 5'-azidouridine via the action of azidase. 5'-Azido-5'-deoxy-2'-O-methyluridine has antiviral activity and can be used as an activator of DNA polymerases. The monophosphate form of this compound can be phosphoramidated to give the corresponding diphosphates, which are used in DNA synthesis to produce double stranded DNA.Fórmula:C10H13N5O5Pureza:Min. 95%Peso molecular:283.24 g/mol5'-(Furan-2-yl)-2’-O-methyluridine
CAS:5'-(Furan-2-yl)-2’-O-methyluridine is a modified nucleoside that is used as an antiviral agent. It is a monophosphate nucleotide analog and has been shown to be active against HIV, herpes simplex virus, cytomegalovirus, and Epstein Barr virus. 5'-(Furan-2-yl)-2’-O-methyluridine is synthesized by the phosphoramidite method and has high purity and quality. The CAS number for this compound is 2095417-32-4.Pureza:Min. 95%N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine is a novel anticancer agent that is modified with a phosphoramidite. It is a nucleoside analog that selectively inhibits DNA polymerases and RNA polymerases, and therefore prevents the synthesis of DNA and RNA. N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine has been shown to be highly active against various cell lines in vitro, including human leukemia cells (HL60), human prostate cancer cells (PC3), human breast cancer cells (MCF7), and human mammary tumor cells (HTB6). This compound has also been shown to have antiestrogenic activity in vivo.Fórmula:C32H33N3O7Pureza:Min. 98 Area-%Peso molecular:571.62 g/mol2'-Deoxy-5'-O-DMT-inosine
CAS:2'-Deoxy-5'-O-DMT-inosine is a chain congener of uridine and cytidine. It is an analog of guanosine, which is found in DNA. 2'-Deoxy-5'-O-DMT-inosine has shown to have cytotoxic effects on the cardiovascular system, as well as inflammatory properties. This drug can also inhibit nitric oxide production and chloride transport. The nitro group in 2'-deoxy-5'-O-DMT-inosine can be removed by ammonolysis or debenzoylation and glycosylation can be added to the molecule with the addition of glucose.Fórmula:C31H30N4O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:554.61 g/mol3'-Amino-2',3'-dideoxyinosine
CAS:3'-Amino-2',3'-dideoxyinosine acts as a chain terminator in DNA synthesis due to the absence of a 3'-hydroxyl group. The 3'-amino group allows for the attachment of various molecules to the 3' end of oligonucleotides, and the inosine base introduces the potential for wobble base pairing, making it a specialized tool for research and potential diagnostic applications.Fórmula:C10H13N5O3Pureza:Min. 95%Peso molecular:251.24 g/molXanthosine 5'-monophosphate disodium salt
CAS:Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Fórmula:C10H11N4Na2O9PPureza:Min. 95%Forma y color:White Slightly Yellow PowderPeso molecular:408.17 g/mol3’-Azido-3’-deoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-Azido-3’-deoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%
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