Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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2,2'-Anhydro-L-uridine
CAS:2,2'-Anhydro-L-uridine is a nucleoside used in for research purposes. It is of particular interest due to it being an L-isomer which is different from the D-form sugars used by the human body. It is useful to study these kinds of molecules for their use in medicine, especially as antiviralsFórmula:C9H10N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:226.19 g/molN4-Acetyl-2'-deoxycytidine
CAS:N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.Fórmula:C11H15N3O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:269.25 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite is a novel monophosphate derivative that is used as an activator for DNA synthesis. This compound is synthesized by reacting 2,4,6-triisopropylbenzenesilyl chloride with 5'-O-tritylthymidine 3'-hydroxyl in the presence of a base. The resulting intermediate is then converted to the desired product with 1,1'-carbonyldiimidazole and 2-(N,N-dimethylamino)ethoxychloroformate. 2'-O-tert-Butyldimethylsilyl-5'-O-tritylthymidine 3'-CE phosphoramidite has been shown to be effective against hepatitis B virus and herpes simplex virus type 1 (HSV1).Fórmula:C44H59N4O7PSiPureza:Min. 95%Peso molecular:815.04 g/molN6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an activator of ribonucleosides and deoxyribonucleosides. It is a novel synthetic nucleoside, which has high quality and purity. The chemical modification of the base allows for the synthesis of DNA with modified bases. This product has been shown to have anticancer effects in vitro and in vivo, as well as antiviral activities against HIV.Fórmula:C39H54N7O6PSiPureza:Min. 95%Peso molecular:775.97 g/molO2-3'-anhydro-β-D-fructofuranosyluracil
O2-3'-anhydro-beta-D-fructofuranosyluracil is a novel nucleoside analogue that has antiviral and anticancer properties. It is synthesized by the reaction of beta-D-fructofuranosyluracil with phosphoramidites. The product is purified by HPLC and characterized by IR spectroscopy, UV spectroscopy, and mass spectrometry.Pureza:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleoside. It is an activator of DNA and RNA synthesis, which can be used to synthesize deoxyribonucleosides and ribonucleosides. This compound has been shown to have anticancer and antiviral properties. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is also used as a high quality synthetic building block for the synthesis of phosphoramidites.Fórmula:C48H56N5O9PPureza:Min. 97 Area-%Forma y color:PowderPeso molecular:877.98 g/mol8-Bromoguanosine hydrate
CAS:8-Bromoguanosine hydrate is a brominated form of guanosine. It is used as a marker for colorectal cancer in urine samples. 8-Bromoguanosine hydrate can be used to calibrate the results of chromatographic analyses and to identify metabolic disorders, such as fatty acid oxidation defects. The compound is also an endogenous ligand that interacts with adenosine receptors and may have pro-apoptotic effects on cancer cells by triggering their death. 8-Bromoguanosine hydrate has been shown to be more effective than other brominated nucleosides in inducing apoptosis in malignant cells, including colorectal carcinoma cells.Fórmula:C10H12BrN5O5·xH2OPureza:Min. 95%Forma y color:PowderPeso molecular:362.14 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-MMT-cytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-MMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analog that has been synthesized by the incorporation of a methyl group at the 5′ position. This modification results in an increased cytotoxicity and cellular uptake in cancer cells. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-MMT-cytidine 3'-CE phosphoramidite also inhibits the replication of HIV and herpes simplex virus type 1 (HSV1) and type 2 (HSV2), which are responsible for AIDS and genital herpes, respectively.
N4 - Benzoyl - 2 ' - O - tert - butyldimethylsilyl - 5 ' - O - MMT - cytidine 3' CE phosphoramFórmula:C51H64N5O8PSiPureza:Min. 95%Peso molecular:934.17 g/mol5-Hydroxycytidine
CAS:5-Hydroxycytidine is a pyrimidine nucleoside that is found in DNA and RNA. It can be produced by the conversion of cytidine 5-monophosphate to cytidine 5'-diphosphate, which is then hydrolyzed to produce 5-hydroxycytidine. This conversion requires the enzyme cytidylate kinase. The structure of 5-hydroxycytidine differs from other pyrimidine nucleosides as its hydroxyl group does not have an acidic proton present. Biological functions that have been attributed to 5-hydroxydihydrocytidylic acid include its ability to inhibit translation and induce cell death in lung cells. This compound has also been shown to modify DNA duplexes and form bioconjugates with proteins or small molecules, such as fluorescein and digoxigenin. These modifications are used in analytical methods such as phase chromatography, nuclear magnetic resonance spectroscopy
Fórmula:C9H13N3O6Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:259.22 g/molN4-Benzoyl-5'-O-DMT-cytidine
CAS:N4-Benzoyl-5'-O-DMT-cytidine is a novel modified nucleoside that can be phosphorylated by T4 kinase to form 5'-O-DMT-N4-benzoyl cytidine, which is an antiviral agent. This active compound is also an activator of DNA polymerases and has anticancer properties. N4-Benzoyl-5'-O-DMT cytidine has been shown to inhibit the replication of HIV in human cells and inhibit tumor growth in animal models. It has been synthesized with high quality and high purity, and has been assigned CAS No. 81246-76-6.Fórmula:C37H35N3O8Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:649.69 g/mol6-Amino-1-(2'-deoxy-β-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-beta-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a synthetic compound that has antiviral activity. It is a monophosphate nucleotide analogue that inhibits the synthesis of viral DNA by competing with natural diphosphates and triphosphates for incorporation into the growing chain. The molecule is activated by addition of an appropriate activator, such as 5'-triphosphate or 5'-diphosphate. 6-Amino-[1-(2'-deoxy-beta-D-ribofuranosyl)-4]-methoxy-[1H]- pyrazolo[3,4-d]pyrimidine is novel and structurally distinct from other antiretroviral nucleosides.
Pureza:Min. 95%6-Chloro-3'-deoxy-3'-fluoroinosine
6-Chloro-3'-deoxy-3'-fluoroinosine (6-Cl-dF) is an analog of the nucleotide base, adenosine. It has been shown to be effective in the treatment of cancer and HIV infections. 6-Cl-dF inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase, which are enzymes that are required for DNA replication. 6-Cl-dF has been shown to inhibit viral replication by blocking reverse transcriptase (an enzyme necessary for viral replication). This drug has also been shown to have antiangiogenic properties.Fórmula:C10H10ClFN4O3Pureza:Min. 95%Peso molecular:288.66 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.Fórmula:C47H54N5O9PPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:863.96 g/molIsocytidine
CAS:Isocytidine, also known as 2-amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone, have broad antitumor activity targeting indolent lymphoid malignancies.Fórmula:C9H13N3O5Pureza:Min. 95%Forma y color:PowderPeso molecular:243.22 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a nucleoside analogue that is synthesized by the condensation of 5'-O-DMT-N6-phenoxyacetyladenosine and 2'-deoxyadenosine. It has antiviral, anticancer and immunomodulatory properties. This compound is novel and modified in that it contains a silyl group at the 2' position, which renders the molecule inactive as an inhibitor of human thymidine kinase. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite inhibits viral replication by interfering with DNA synthesis. It also has been shown to inhibit tumor cell proliferation and promote apoptosis in vitroFórmula:C54H68N7O9PSiPureza:Min. 95%Forma y color:PowderPeso molecular:1,018.25 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate triethylammonium salt - Aqueous solution
CAS:2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate triethylammonium salt - Aqueous solution is a nucleoside analog for research purposesFórmula:C9H14F2N3O13P3·C24H60N4Forma y color:Colorless PowderPeso molecular:907.9 g/molN4-Acetyl-5'-O-Tritylcytidine
N4-Acetyl-5'-O-Tritylcytidine is a novel nucleoside that is a phosphoramidite. It is used in the synthesis of ribonucleosides, deoxyribonucleosides, and DNA. N4-Acetyl-5'-O-Tritylcytidine has antiviral activities.Fórmula:C30H29N3O5Pureza:Min. 95%Peso molecular:511.57 g/molCytidine 5'-monophosphate disodium salt
CAS:Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.Fórmula:C9H12N3Na2O8PPureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:367.16 g/mol3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine
CAS:3-Ribofuranosyl-4,9-dihydro-4,6,7-trimethyl-9-oxoimidazo(1,2-a)purine is a nucleoside with the chemical formula C8H8N5O5. It is used in research as a phylogenetic marker and index fossil. 3RFP is found as a natural product in some plants and animals, but it can also be synthesized chemically. 3RFP has been shown to posttranscriptionally inhibit rRNA synthesis by binding to the ribonucleotide reductase enzyme. This inhibits the production of RNA needed for protein synthesis and cell division. 3RFP has been shown to have structural diversity that has yet to be fully explored due to its rarity.Pureza:Min. 95%
![6-Amino-1-(2'-deoxy-β-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNA162934.webp&w=3840&q=75)
