Nucleósidos
Se han encontrado 3570 productos de "Nucleósidos"
Cytidine-5-carboxylic acid sodium
CAS:Cytidine-5-carboxylic acid sodium salt is a nucleoside that is used as an activator for the synthesis of phosphoramidites. It is also used in anticancer and antiviral research as a component of DNA. Cytidine-5-carboxylic acid sodium salt is available in high purity, with a monophosphate form and diphosphate forms available.Fórmula:C10H13N3O7•NaPureza:Min. 95%Forma y color:PowderPeso molecular:310.21 g/mol2'-Deoxyinosine-5'-monophosphate disodium salt
CAS:2'-Deoxyinosine-5'-monophosphate disodium salt is a synthetic nucleoside, phosphoramidite, and diphosphate that is used in the synthesis of DNA. It has been shown to have antiviral effects against HIV and herpes simplex virus type 2 (HSV-2). This drug also has anticancer activity and is an activator of novel nucleosides.Fórmula:C10H11N4Na2O7PPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:376.17 g/molPolycytidylic acid
CAS:Polycytidylic acid is a single stranded RNA analog which is combined with Polyinosinic acid to form a stable duplex structure known as Polyinosinic acid-polycytidylic acid (Poly I:C). PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes. We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products.
For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Pureza:Min. 95%2-Hydrazinoadenosine
CAS:2-Hydrazinoadenosine is an active analogue of adenosine. It is a potent agonist for the adenosine receptor subtypes A1 and A2A with high affinity. 2-Hydrazinoadenosine has been shown to inhibit cardiac contractility in animal models, as well as to produce hypotension, bradycardia, and bronchodilation in humans. This drug also has a functional effect on the heart by binding to adenosine receptors, which leads to the inhibition of catecholamine release. This drug is used clinically as an antiarrhythmic agent and a vasodilator in coronary artery disease.
Fórmula:C10H15N7O4Pureza:Min. 95%Forma y color:PowderPeso molecular:297.27 g/mol2-Chloroadenosine hemihydrate
CAS:2-Chloroadenosine hemihydrate is a synthetic purine nucleoside analog, closely related to adenosine, with a chlorine atom substituted at the 2-position on the adenine ring. This molecule has potential application in research.Fórmula:C10H12ClN5O4H2OPureza:Min. 95%Forma y color:PowderPeso molecular:310.69 g/mol5-Fluorouridine-5'-triphosphate sodium salt
CAS:5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.Fórmula:C9H14N2O15P3FPureza:Min. 95%Peso molecular:502.13 g/moldNTP bundle, 4 x 100mM aqueous solution
CAS:Each dNTP supplied in a separate vialPureza:Min. 99 Area-%Forma y color:Clear Liquid2'-Deoxy-N2,3-ethenoguanosine
CAS:2'-Deoxy-N2,3-ethenoguanosine is a novel antiviral agent that is phosphorylated by the viral enzyme ribonucleotide reductase and then incorporated into viral DNA. This compound is an activator of deoxyribonucleoside monophosphate activity and inhibits the synthesis of DNA and RNA. 2'-Deoxy-N2,3-ethenoguanosine has been shown to inhibit the growth of cancer cells in culture and may be useful for treating cancer.Fórmula:C12H13N5O4Pureza:Min. 95%Peso molecular:291.26 g/mol1-(β-D-Arabinofuranosyl)thymine
CAS:1-(β-D-Arabinofuranosyl)thymine is a nucleoside analog. It has a similar structure to thymidine. It has possible applications in research into the specificity and kinetics of thymidine kinases and has demonstrated antiviral activity against some viruses.Fórmula:C10H14N2O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:258.23 g/molCytarabine
CAS:Fórmula:C9H13N3O5Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:243.229-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)guanine
CAS:9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine is a nucleoside phosphorylase inhibitor that is used to treat inflammatory bowel disease. It has been shown to be effective in treating women with inflammatory bowel disease, and has no significant side effects. 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine inhibits the bacterial enzyme nucleoside phosphorylase, which is responsible for the conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). This inhibition prevents the synthesis of DNA and RNA by blocking the conversion of GTP and GDP into AMP and GMP. The drug binds to the active site of nucleoside phosphorylase, which is located in the bacterial cytoplasmic membrane. 9-(2'-Deoxy-2'-fluoroFórmula:C10H12FN5O4Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:285.24 g/molAdenosine-5’-triphosphate disodium salt trihydrate
CAS:Please enquire for more information about Adenosine-5’-triphosphate disodium salt trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C10H14N5O13P3·2Na·3H2OPeso molecular:605.19 g/mol2'-Deoxy-a-guanosine
CAS:2'-Deoxy-a-guanosine is a nucleoside that is modified by the substitution of its ribose sugar with deoxyribose. It is used in anticancer and antiviral research. This chemical has been shown to inhibit DNA synthesis and RNA polymerase activity. 2'-Deoxy-a-guanosine has also been shown to have an anti-inflammatory effect, which may be due to its inhibition of prostaglandin synthesis.Fórmula:C10H13N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:267.25 g/mol8-Amino[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxy adenosine
CAS:8-Amino-[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxyadenosine is a novel nucleoside phosphoramidite that has antiviral and anticancer activity. It is currently under development as a potential treatment for Hepatitis C, HIV and cancer. 8-Amino-[1''-(N''-dansyl)-4''-aminobutyl]-5'-(1-aziridinyl)-5'-deoxyadenosine is an activator of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. It also inhibits the synthesis of DNA and RNA by inhibiting the enzyme DNA gyrase and topoisomerase IV. 8-Amino-[1''-(N''-dansyl)-4''-aminobutylFórmula:C28H37N9O5SPureza:Min. 95%Forma y color:PowderPeso molecular:611.72 g/mol2'-O-Methylinosine
CAS:2'-O-Methylinosine is a nucleoside that is structurally related to inosine. It has been shown to induce apoptotic cell death in HIV-infected cells by inhibiting the synthesis of rRNA and by inhibiting the activity of the transcriptase enzyme. 2'-O-Methylinosine has also been shown to inhibit the replication of RNA viruses, such as herpes simplex virus and cytomegalovirus, and it can be used as an experimental model for studying apoptosis. 2'-O-Methylinosine can be synthesized from inosine using a chromatographic method that utilizes hydroxylamine. The chemical structure of this nucleoside is amphipathic, which allows it to bind both DNA and RNA strands.Fórmula:C11H14N4O5Pureza:Min. 99 Area-%Forma y color:White PowderPeso molecular:282.25 g/mol2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine
CAS:2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.Fórmula:C41H51N5O8SiPureza:Min. 98 Area-%Forma y color:Off-White PowderPeso molecular:769.96 g/molUridine
CAS:Fórmula:C9H12N2O6Pureza:>98.0%(T)(HPLC)Forma y color:White powder to crystalPeso molecular:244.202'-Deoxycytidine-5'-diphosphate trisodium salt hydrate
CAS:2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a nucleoside that is used as an antiviral agent in the treatment of herpes zoster and varicella zoster. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis. 2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a novel nucleotide analogue that has been modified to improve its stability, solubility and bioavailability. It can be used as a starting material for the synthesis of phosphoramidites by reacting with phosphorous pentoxide at elevated temperatures and pH. CAS No. 151151-32-5Fórmula:C9H12N3O10P2·Na3Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:453.12 g/mol2'-Deoxy-L-uridine
CAS:2'-Deoxy-L-uridine is a nucleoside that is found in the human body. It phosphorylates l-thymidine, which is a natural substrate, and this reaction prevents the formation of diphosphate from d-ribose 5'-monophosphate. 2'-Deoxy-L-uridine is an exogenous substance that inhibits cell growth by affecting protein synthesis and DNA replication. 2'-Deoxy-L-uridine has been shown to be more efficient than wild type uridine in inhibiting cell growth in vitro at concentrations of 1 mM or greater. The enantiomers of 2'-deoxy-L-uridine affect cell growth differently, with the (R)-enantiomer being more potent than the (S)-enantiomer.
Fórmula:C9H12N2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:228.2 g/mol2',3'-Di-O-benzoyluridine
CAS:2',3'-Di-O-benzoyluridine is a nucleoside for use in research applications
Fórmula:C23H20N2O8Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:452.41 g/mol
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