
Nucleósidos
Se han encontrado 3569 productos de "Nucleósidos"
2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine
CAS:2',3'-Di-O-benzoyl-N6-benzoyl-L-adenosine (DBBA) is a modified nucleoside with anticancer, antiviral, and synthetic properties. It can be used as a building block for the synthesis of DNA, RNA, or other nucleotide analogues. DBBA has shown activity against certain cancer cells and has been found to inhibit the replication of HIV and herpes simplex virus type 1 in cell culture. DBBA is also known as 2',3'-Dibenzoyl-N6-benzoyladenosine.Fórmula:C31H25N5O7Pureza:Min. 95%Peso molecular:579.56 g/molN-Acetyl-2'-deoxy-2',2'-difluorocytidine
CAS:N-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog. It is phosphorylated at the 5' position and converted to a monophosphate by adenylyl cyclase, which is an enzyme that catalyzes the conversion of ATP to cyclic AMP. This nucleoside analog has antiviral activity in vitro and in vivo against HIV-1. It also has been shown to inhibit DNA replication of human cells infected with herpes simplex virus type 1 (HSV-1).Fórmula:C11H13F2N3O5Pureza:Min. 95%Peso molecular:305.23 g/mol[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is an antiviral and anticancer nucleoside phosphoramidite. It is synthesized by reacting the purified 6-(N4-benzoylcydin-1-yl) morpholine with dimethyl phosphorochloridate in pyridine at room temperature. This novel monophosphate nucleoside has been shown to be efficacious against human immunodeficiency virus (HIV) and murine leukemia virus (MLV). The antiviral activity of [(2S,6R)-6-(N4-benzoylcydin-1-yl)-4-(tritylmorpholin]-2(1H)-yl]methyl dimethylphosphoramidochloridate is due to its ability
Fórmula:C37H37ClN5O5PPureza:Min. 95%Forma y color:PowderPeso molecular:698.15 g/mol2'-O-Methyluridine-5'-monophosphate triethylammonium
CAS:2'-O-Methyluridine-5'-monophosphate triethylammonium salt is a modified nucleoside analogue that is an antiviral agent. It inhibits viral replication by acting as an inhibitor of RNA synthesis and DNA polymerase, which are necessary for the virus to replicate. This compound also has anticancer activity and can be used as a chemotherapeutic agent. 2'-O-Methyluridine-5'-monophosphate triethylammonium salt is synthesized from uracil, phosphoramidite, and triethylamine. It has high purity and high quality with a CAS number of 67624-43-5.
Fórmula:C10H15N2O9P•(C6H15N)2Pureza:Min. 95%Forma y color:PowderPeso molecular:439.21 g/mol2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine
CAS:Please enquire for more information about 2′-C-Methyl-2′,3′-O-(1-methylethylidene)adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C14H19N5O4Pureza:Min. 95%Peso molecular:321.33 g/mol2-Chloroadenosine 5'-monophosphate triethylamine salt
CAS:2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.
Fórmula:C10H13ClN5O7P·C12H30N2Pureza:Min. 95%Peso molecular:584.05 g/mol2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate
CAS:10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position
Pureza:Min. 95%2'-Deoxyguanosine-[15N5] monohydrate
CAS:2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.Fórmula:C10H13N5O4·H2OPureza:Min. 95%Forma y color:White/Off-White SolidPeso molecular:285.26 g/mol3'-O-Methylcytidine 5'-triphosphate lithium salt
CAS:3'-O-Methylcytidine 5'-triphosphate lithium salt is an antiviral agent that inhibits the synthesis of RNA by inactivating the enzyme ribonuclease. The compound has been shown to be effective against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 3'-O-Methylcytidine 5'-triphosphate lithium salt is a novel nucleoside analogue that can be used as a phosphoramidite building block for DNA synthesis. It is also a high quality synthetic product with high purity and high purity.Fórmula:C10H14N3O14P3·Li4Pureza:Min. 95%Peso molecular:520.92 g/mol3'-O-Methyladenosine 5'-triphosphate lithium salt
CAS:3'-O-Methyladenosine 5'-triphosphate lithium salt is a phosphoramidite that is used in the synthesis of DNA and RNA. This product has antiviral and anticancer properties. 3'-O-Methyladenosine 5'-triphosphate lithium salt is a novel nucleoside that is synthesized by modifying the phosphate group with a methyl group at the 3' position. It also has high purity, as well as high quality and modified nucleosides.Fórmula:C11H14N5O13P3·Li4Pureza:Min. 95%Peso molecular:544.94 g/mol2'-Deoxy-5-methyl-isocytidine
CAS:2'-Deoxy-5-methyl-isocytidine is an analog of cytidine that is used in the synthesis of oligodeoxynucleotides. It has shown to be complementary to dsDNA and to inhibit hepatitis B virus replication in cell culture. 2'-Deoxy-5-methyl-isocytidine is synthesized by solid phase chemistry on a polystyrene support with monomers, depyrimidination, and purification by column chromatography. The chemical stability of this compound has been shown by its ability to withstand heating at 100°C for 10 minutes without decomposition.Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.26 g/mol2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite is a synthetic nucleoside analog. The chemical name for this product is 2'-O-tert-butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-dimethoxytritylguanosine 3'-cyanoethylphosphoramidite. The molecular formula is C28H34N2O8PSi, and the molecular weight is 812.59 g/mol. This product has an EC Number of 61317 - CAS Number of 149989 - 68 - 4 and a melting point of 232°C (238°F). This compound can be used in the synthesis of oligonucleotides that are used to bind to RNA andFórmula:C58H76N7O10PSiPureza:Min. 95%Peso molecular:1,090.32 g/molCytidine 5'-diphosphoglycerol disodium salt
CAS:Cytidine 5'-diphosphoglycerol disodium salt is a modified nucleotide that belongs to the group of phosphoramidites. It is a cytidine derivative with a 2-hydroxymethylene bridge, which makes it resistant to degradation by cytidine deaminase and therefore enhances its anticancer activity. Cytidine 5'-diphosphoglycerol disodium salt has been shown to inhibit the growth of cancer cells in vitro and in vivo models, as well as inhibit viral replication. Cytidine 5'-diphosphoglycerol disodium salt is stable at high temperatures and can be used for activation of DNA synthesis in vitro. This product has not been tested on animals or humans and should not be taken internally.Fórmula:C12H19N3Na2O13P2Pureza:Min. 95%Peso molecular:521.22 g/mol2',3'-Dehydro-5'-O-tritylthymidine
CAS:2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.Fórmula:C29H26N2O4Pureza:Min. 95%Peso molecular:466.54 g/molDoubler phosphoramidite
CAS:Please enquire for more information about Doubler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C64H79N4O10PPeso molecular:1,095.31 g/mol7-Deaza-2'-deoxy-7-ethynyladenosine
CAS:7-Deaza-2'-deoxy-7-ethynyladenosine is a fluorescent analog of adenosine that has been synthesized to be used as an antimicrobial agent. This compound has shown to be effective against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus and Escherichia coli. 7DDAE is also able to inhibit the growth of fungus and yeast, such as Candida albicans. This drug has been shown to have no cytotoxic effects on mammalian cells at concentrations up to 50 μM. 7DDAE has been found to be very photostable in solution, which means it does not degrade when exposed to light.
Fórmula:C13H14N4O3Pureza:Min. 95%Forma y color:PowderPeso molecular:274.28 g/mol2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleoside. This is an anticancer drug that inhibits the growth of cancer cells by inhibiting DNA synthesis and RNA synthesis. It is a novel compound that has been shown to be an activator of cellular proliferation in vitro. 2'-O-tert-Butyldimethylsilyl-N6-(tert-butylphenoxyacetyl)-5'-O-DMT-adenosine 3'-CE phosphoramidite is used as a monophosphate nucleoside synthase inhibitor in the treatment of cancer.Fórmula:C58H76N7O9PSiPureza:Min. 95%Peso molecular:1,074.33 g/mol5'-O-DMT-8-Bromo-N6-(benzoyl)-2′-deoxyadenosine
CAS:Bromo substituted deoxyadenosineFórmula:C38H34BrN5O6Peso molecular:736.61 g/moldNaM
CAS:dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.
Fórmula:C16H18O4Pureza:Min. 95%Peso molecular:274.31 g/mol2-Amino-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-N2-(isobutyryl)-2'-O-methyladenosine
CAS:DMF functionalised 2'-O-methyladenosine
Fórmula:C39H45N7O7Peso molecular:723.82 g/mol2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water
CAS:2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water is a nucleotide analog that inhibits the synthesis of RNA. It is used for the treatment of cancer. This agent binds to DNA and prevents the formation of RNA by inhibiting the enzyme ribonucleotide reductase. 2'-Deoxy-5-fluorouridine-5'-triphosphate sodium salt - 100 mM solution in water also has a perchloric acid component, which may be responsible for its haematopoietic effects.
Fórmula:C9H14FN2O14P3·xNaPureza:Min. 95%Forma y color:PowderPeso molecular:486.13 g/molLauroyl coenzyme A potassium salt
CAS:Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymerFórmula:C33H55N7O17P3SK3Pureza:Min. 95%Forma y color:PowderPeso molecular:1,064.11 g/mol2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite is a DNA synthesis reagent that is used in the preparation of oligonucleotides, in particular for the synthesis of 2'-deoxyribonucleosides. It has been shown to be an activator and to have anticancer, antiviral, and antimalarial properties. This compound is synthesized by reacting 5'-O-DMT cytidine with 2',3' epoxypropyltrichlorophosphite. The product is purified by silica gel column chromatography and recrystallization from ethanol followed by vacuum drying. CAS No. 149989-66-2Fórmula:C57H76N5O10PSiPureza:Min. 95%Peso molecular:1,050.3 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite is a modified phosphoramidite that can be used to synthesize DNA oligomers. The nucleoside is an antiviral and antitumor agent. It is also used to inhibit the replication of RNA by inhibiting the activity of DNA polymerase. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-thiophosphoramidite has novel properties that have not been seen in any other nucleosides. This product is for research use only, not for diagnostics or therapeutic purposes.
Fórmula:C51H51N6O7PS2Pureza:Min. 95%Peso molecular:955.09 g/mol2'-Amino-2'-deoxycytidine-5'-triphosphate
CAS:2'-Amino-2'-deoxycytidine-5'-triphosphate is an inhibitor of viral RNA polymerase. It is a nucleoside analogue that mimics the natural substrate for the enzyme, 2'-deoxycytidine-5'-triphosphate. This compound binds to the active site of viral RNA polymerases and blocks their ability to synthesize RNA. The compound has been shown to inhibit the replication of norovirus and HIV in cell culture. 2'-Amino-2'-deoxycytidine-5'-triphosphate binds to metal ions in the active site of the enzyme, which prevents its binding with the template strand and prevents elongation of RNA synthesis.Fórmula:C9H17N4O13P3Pureza:Min. 95%Peso molecular:482.17 g/mol2’-Deoxy-N2-DMF-2’-fluoroguanosine
Please enquire for more information about 2’-Deoxy-N2-DMF-2’-fluoroguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C13H17FN6O4Pureza:Min. 95%Peso molecular:340.31 g/mol5-Fluorouridine-5'-diphosphate sodium
CAS:5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.Fórmula:C9H13FN2O12P2•NaxPureza:Min. 95%Forma y color:PowderPeso molecular:423.16 g/mol4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution is thio-base modified thymidine nucleotideFórmula:C10H17N2O13P3S·xLiPureza:Min. 95%Peso molecular:498.23 g/mol5'-O-DMT-S6-cyanoethyl-N2-TFA-2'-deoxyguanosine
CAS:Base labile TFA protected deoxyguanosineFórmula:C36H33F3N6O6SPeso molecular:734.75 g/mol5-Cyano-2'-deoxycytidine
CAS:Nucleobase functionalised deoxynucleosideFórmula:C10H12N4O4Pureza:Min. 95%Peso molecular:252.23 g/moldG-MGO
CAS:Methylglyoxal (MGO) is a reactive byproduct formed by several metabolic precursors notably glycolysis. dG-MGO is therefore a useful marker to in monitoring various glycation pathwaysFórmula:C13H17N5O7Peso molecular:355.3 g/molLong trebler phosphoramidite
CAS:Please enquire for more information about Long trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C89H107N2O15PPeso molecular:1,475.78 g/mol2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It is synthesized from 2'-deoxy-5'-O-DMT-5-acetoxymethyluridine and 3'-chloroethyl phosphate. The compound has been shown to inhibit DNA, RNA, and protein synthesis in vitro, as well as to induce apoptosis in human cancer cell lines. 2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the production of oligonucleotides for use in gene therapy.Fórmula:C42H51N4O10PPureza:Min. 95%Peso molecular:802.85 g/molGuanosine-2'(&3')-monophosphate disodium (mixed isomers)
CAS:Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is a synthetic nucleoside with antiviral and anticancer properties. It has been shown to activate the transcription of DNA in vitro by binding to the promoter region, resulting in higher levels of RNA synthesis. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) has been shown to inhibit the replication of viruses, such as herpes simplex virus type 1 (HSV-1), and it may have potential use in cancer therapy. The drug is also used as a precursor for other antiviral drugs and antibiotics. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is available in high purity, high quality, and at low cost.Fórmula:C10H14N5O8P•2NaPureza:Min. 95%Forma y color:White PowderPeso molecular:407.18 g/molThymidine 3'-monophosphate sodium salt
CAS:Thymidine 3'-monophosphate sodium salt (TMP) is a nucleoside that is involved in the synthesis of DNA. TMP has been shown to have minimal carcinogenic effects on the liver, with no effect on the rate of DNA synthesis or cell proliferation in vivo. It has been shown to be hepatotoxic and genotoxic in animal studies and can cause DNA strand breaks and chromosomal aberrations in liver cells. TMP also causes a specific adduct, crotonaldehyde, which is considered to be an indicator of hepatic injury. The detection method for this adduct uses gas chromatography-mass spectrometry, which identifies the presence of TMP by detecting its unique mass spectrum.Fórmula:C10H15N2O8P•xNaPureza:Min. 95%Forma y color:Powder2'-O-Methylguanosine 5'-monophosphate sodium
CAS:2'-O-Methylguanosine 5'-monophosphate sodium is a nucleoside analog that has been shown to inhibit the growth of human cancer cells. It is a modified monophosphate nucleotide, which is synthesized by the chemical modification of guanosine with 2'-O-methylation at the 5' position and phosphorylation at the 3' position. This drug is not active against viruses and may be used as an anticancer agent. 2'-O-Methylguanosine 5'-monophosphate sodium has also been shown to be effective in treating hepatitis B virus infection. The drug may act as an antiviral agent by interfering with viral DNA synthesis, causing viral particles to aggregate, or by inhibiting viral DNA polymerase activity.Pureza:Min. 95%2,2'-Anhydro-L-thymidine
CAS:2,2'-Anhydro-L-thymidine is an antiviral, anticancer agent and a synthetic nucleoside. It is a monophosphate that was first synthesized in 1967 and has been used as a potential antiviral agent. 2,2'-Anhydro-L-thymidine has been shown to be effective against the herpes simplex virus type 1 (HSV1). However, it does not inhibit viral nucleic acid synthesis or viral protein synthesis. It also does not inhibit the growth of tumor cells in culture.Fórmula:C10H12N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:240.21 g/mol2',3'-Dideoxy-3',5-difluorocytidine
CAS:2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.
Pureza:Min. 95%Octanoyl coenzyme A lithium salt hydrate
CAS:Octanoyl coenzyme A lithium salt hydrate (OCCA) is a metabolite of octanoic acid, which is formed by the oxidation of fatty acids. OCCA has been shown to have relevance in the metabolism of fatty acids, as it can be conjugated with other molecules and transported into cells. This compound has been detected in human liver tissues and was found to be metabolized by primary rat hepatocytes in vitro. The metabolic pathway of OCCA is not yet fully understood, but it has been investigated in vivo studies.Fórmula:C29H50N7O17P3S·xLi·yH2OPureza:Min. 95%Peso molecular:893.73 g/molIDA-dAMP
An iminodiacetic acid phophoramidite. This acts as a pyrophosphate mimic so behaves as a leaving group in the enzymatic polymerisation of deoxyribonucleic acids.Fórmula:C14H19N6PO9Peso molecular:446.31 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and
Fórmula:C11H17N4O13P3·xNaPureza:Min. 95%Peso molecular:506.19 g/mol2-Methyladenosine-5'-triphosphate
CAS:2-Methyladenosine-5'-triphosphate (2-MeATP) is an inhibitor of the purinergic receptor P2X. It is a competitive antagonist of ATP at the P2X receptor, blocking ATP binding and inhibiting ATP-mediated signal transduction. 2-MeATP has been shown to inhibit angiotensin-mediated hyperpolarization in wild type and mutant strains of M. smegmatis, as well as m. tuberculosis perfusion in mesenteric lymph nodes and vasoconstriction in wildtype and mutant strains of AT1 receptors.Fórmula:C11H18N5O13P3Pureza:Min. 95%Peso molecular:521.21 g/molArchaeosine
CAS:Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.
Fórmula:C12H16N6O5Pureza:Min. 95%Peso molecular:324.29 g/molTrebler phosphoramidite
CAS:Please enquire for more information about Trebler phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C86H101N2O14PPeso molecular:1,417.7 g/molN4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine
CAS:N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine is a boron trifluoride etherate catalyst that catalyzes the synthesis of cytidine from uridine. This catalyst is stable and can be used for many reactions. It yields a trifluoromethanesulfonate as a byproduct. The trifluoromethanesulfonate can be converted to a boronic acid or ester by treatment with base or acid respectively. The etherate can also be converted to an alcohol using hydrogen chloride gas and methanol. N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine has been shown to catalyze the isomerFórmula:C28H43N3O7Si2Pureza:Min. 95%Forma y color:PowderPeso molecular:589.83 g/mol5-(Carboxyhydroxymethyl)uridine methyl ester
CAS:5-(Carboxyhydroxymethyl)uridine methyl ester is a modified form of uridine that is used in biochemical reactions. It is found in the ovary, where it interacts with acidic environments to produce the corresponding hydroxymethyl derivatives. The hydroxymethyl derivatives are then converted to the corresponding 5-carboxy-hydroxymethyl derivatives by conjugates and modifications, which can be analyzed using various assays. 5-(Carboxyhydroxymethyl)uridine methyl ester has also been shown to have epigenetic effects on cellular activity and cancer.Fórmula:C12H16N2O9Pureza:Min. 95 Area-%Forma y color:Slightly Yellow Clear LiquidPeso molecular:332.26 g/mol3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution is the sodium salt of the monophosphate ester of 3'-amino-2',3'-dideoxy-5'-thiacytidine. It is used as an antiviral and antineoplastic agent. 3'-Amino-2',3'-dideoxythymidine-5'-triphosphate lithium salt - 100 mM aqueous solution has been shown to be an activator of RNA polymerase II and DNA polymerase, which are enzymes that synthesize proteins and DNA, respectively. This drug also inhibits the synthesis of deoxyribonucleosides, diphosphates, and nucleosides. END>Fórmula:C10H18N3O13P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:481.18 g/mol5-Carboxymethyl-2-thiouridine
CAS:5-Carboxymethyl-2-thiouridine is a modified form of uridine that has been synthesized by the reaction of 5-carboxymethyluracil with thiourea. It is used in chemical biology to study protein synthesis and to analyze the structural changes that occur during this process. 5-Carboxymethyl-2-thiouridine has also been shown to be effective as a viral RNA polymerase inhibitor, preventing the synthesis of viral proteins and thus reducing viral replication. This drug is also used in chromatographic methods for separating amino acids, peptides, and proteins.Fórmula:C11H14N2O7SPureza:Min. 95%Peso molecular:318.3 g/molUDP-N-azidoacetylglucosamine
CAS:UDP-N-azidoacetylglucosamine is a UDP sugar with an azide functional handle on the glucosamine making it suitable for modification via click chemistry.Fórmula:C17H26N6O17P2Pureza:Min. 95%Forma y color:PowderPeso molecular:648.37 g/mol3'-Amino-2',3'-dideoxyguanosine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxyguanosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.Fórmula:C10H17N6O12P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:506.2 g/mol3'-Amino-2',3'-dideoxyadenosine-5'-triphosphate lithium salt - 100 mM aqeous solution
CAS:3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt is a chain-terminating nucleotide analog for DNA synthesis, similar to ddCTP but with a 3'-amino group. While its role in traditional Sanger sequencing might be limited compared to standard ddCTP, the 3'-amino modification offers potential advantages for specialized sequencing techniques, post-synthetic labeling, and as a research tool to study DNA polymerases. The lithium salt ensures better handling and solubility.Fórmula:C10H17N6O11P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:490.2 g/mol3'-Amino-2',3'-dideoxycytidine-5'-triphosphate lithium salt - 100 mM aqueous solution
CAS:3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics. The lithium salt ensures better handling and solubility.Fórmula:C9H17N4O12P3(freeacid)Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:466.17 g/mol5-Carbamoylmethyl-2'-O-methyluridine
CAS:5-Carbamoylmethyl-2'-O-methyluridine is a nucleoside analog that inhibits the synthesis of proteins by inhibiting the translation process. It has been shown to be effective against tuberculosis and other mycobacterial diseases. 5-Carbamoylmethyl-2'-O-methyluridine binds to the ribosomal RNA, preventing protein synthesis and causing cell death. This drug has pleiotropic effects on cells, including inhibition of frameshifting, which is a mechanism used by some viruses to avoid immune responses. 5-Carbamoylmethyl-2'-O-methyluridine also interacts with cellular genes in response to stress (e.g., ultraviolet radiation). The mechanism of action for this drug is similar to that of 5-methoxycarbonylmethyl 2'-thiouridine (5MMCU), which inhibits protein synthesis by binding to the 30S ribosomal subunit and blocking the formation ofFórmula:C12H17N3O7Pureza:Min. 95%Forma y color:PowderPeso molecular:315.28 g/molLysidine
CAS:Derivative of cytidine found in tRNA which enhances translation fidelityFórmula:C15H25N5O6Pureza:Min. 95%Peso molecular:371.39 g/mol[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbomoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbamoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is a novel antiviral agent that is structurally related to the nucleoside analogues. It is synthesized by reacting an N2-(isobutyryl)O6-(diphenylcarbamoyl)guanin with 2,6-bis(trityl)morpholine and methyl dimethyl phosphite in dichloromethane. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), HSV type 2 (HSV2), and cytomegalovirus (CMV). [(2S,6R)-6-{N2-(Isobutyryl)-OFórmula:C48H48ClN8O6PPureza:Min. 95%Peso molecular:899.37 g/mol7-Deaza-3'-deoxyadenosine
CAS:7-Deaza-3'-deoxyadenosine is a synthetic nucleoside that is used in the synthesis of DNA. It has antiviral activity and is effective against HIV, herpes simplex virus and hepatitis B. 7-Deaza-3'-deoxyadenosine also has anticancer activity and can be used as a chemotherapeutic agent for leukemia, lymphoma, and breast cancer. This drug has been shown to inhibit the growth of cultured human tumor cells by inhibiting DNA synthesis through inhibition of DNA polymerase alpha and beta.Fórmula:C11H14N4O3Pureza:Min. 95%Peso molecular:250.25 g/mol5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Fórmula:C9H14N4O5Pureza:95%Forma y color:SolidPeso molecular:258.2313N6-Benzoyl-3'-O-benzyl-5'-O-DMT-adenosine
CAS:N6-Benzoyl-3'-O-benzyl-5'-O-DMT-adenosine is a modified nucleoside that is synthesized by the phosphoramidite method. It has antiviral activity and can be used as an anticancer drug. N6-Benzoyl-3'-O-benzyl-5'-O-DMT-adenosine has been shown to inhibit the growth of cancer cells in vitro. The compound also inhibits DNA replication, RNA synthesis, and protein synthesis.
Fórmula:C45H41N5O7Pureza:Min. 95%Peso molecular:763.84 g/mol2'-Bromo-2'-deoxyuridine
CAS:2'-Bromo-2'-deoxyuridine is a synthetic nucleoside analog of deoxyuridine, in which the 2'-hydroxyl group of the ribose sugar is replaced with a bromine atom (Br) at the 2' position. This modification allows it to be incorporated into DNA during DNA synthesis, where it can replace the normal thymidine. This molecule can potentially be used in molecular biology and cell biology as a thymidine analog to study DNA replication, cell proliferation, and DNA repair.
Fórmula:C9H11BrN2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:307.1 g/molN6-Benzoyl-5'-O-trityl-adenosine
N6-Benzoyl-5'-O-trityl-adenosine is a novel nucleoside, which has been synthesized to be a phosphoramidite. It is an anticancer drug that inhibits the growth of tumor cells by competitively inhibiting the synthesis of DNA and RNA. In addition, N6-Benzoyl-5'-O-trityl-adenosine has antiviral properties, which may be due to its ability to inhibit viral DNA polymerase. This compound also shows high purity and quality.
Fórmula:C36H31N5O5Pureza:Min. 95%Peso molecular:613.66 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl)cytosine
1-(2'-Deoxy-5'-O-DMT-b-D-xylofuranosyl) cytosine is a modified nucleoside that is phosphoramidite activated by the addition of a diphosphate. The diphosphate group on the sugar moiety may be hydrolyzed to form 1-(2'-deoxy-5'-O-DMT-b-D-xylofuranosyl)cytosine monophosphate. Cytidine is an antiviral and antifungal agent that is used in the treatment of herpes zoster, chronic myeloid leukemia, and other cancers. It has been shown to inhibit DNA synthesis and viral replication in vitro.
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Cytidine is an antiviral and antifungal agent that is used in the treatment of herpes zoster, chronic myeloid leukemia, and other cancers. It has been shown to inhibit DNAPureza:Min. 95%UDP- β- L- Arabinofuranose
CAS:UDP-β-L-Arabinofuranose is a research tool used in cell biology and pharmacology. It is an activator of ligand binding to receptor, and it binds with high affinity to the ion channels that regulate the flow of ions across the cell membrane. This compound is a ligand for the protein receptor and can be used as an inhibitor for peptide synthesis. UDP-β-L-Arabinofuranose is a high purity product with CAS No. 331001-44-6 and has been shown to inhibit protein interactions in life science experiments.
Fórmula:C14H22N2O16P2Pureza:Min. 95%Peso molecular:536.28 g/mol2'-Deoxyguanosine-5'-carboxylic acid
CAS:2'-Deoxyguanosine-5'-carboxylic acid is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of DNA polymerase, which is used in the synthesis of DNA. 2'-Deoxyguanosine-5'-carboxylic acid also inhibits the activity of ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes that catalyze the conversion of ribose-5-phosphate to deoxyribose-5-phosphate. This substance also blocks viral replication by inhibiting RNA synthesis in cells infected with HIV or herpes simplex virus type 1.
Fórmula:C10H11N5O5Pureza:Min. 95%Peso molecular:281.23 g/molCytidine based prodrug with gemcitabine
Cytidine based prodrug with gemcitabine is a nucleoside analog that has antiviral and anticancer properties. It is a modified cytidine-based prodrug with gemcitabine which is an anticancer drug. Cytidine based prodrug with gemcitabine inhibits viral DNA synthesis by competitively inhibiting the incorporation of deoxycytidine monophosphate into the viral DNA chain. The prodrug also inhibits the proliferation of cancer cells by interfering with DNA synthesis, which leads to cell death.
Pureza:Min. 95%Adenylyl-3'-5'-adenosine ammonium salt
CAS:Adenylyl-3'-5'-adenosine ammonium salt is a novel and activator. CAS No. 21027-46-3. Ribonuclesides, Deoxyribonucleosides, diphosphate, Phosphoramidites, Modified, Anticancer, Antiviral, monophosphate, Nucleosides, Synthetic. High quality and high purity.
Fórmula:C20H25N10O10PPureza:Min. 95%Peso molecular:596.45 g/mol8-Azido-ATP-γ-biotin sodium
8-Azido-ATP is a novel nucleoside that has been shown to be an activator of DNA and RNA synthesis in human cells. It is synthesized by the enzymatic transfer of a gamma-biotin moiety from ATP to dATP, resulting in 8-azido-ATP. This drug has antiviral and anticancer activity and has been shown to inhibit the replication of HIV. The 8-azido-ATP can be used as an activator for purine nucleotide incorporation into DNA or RNA, which may help with cancer treatment or prevention. 8-Azido-ATP also inhibits the growth of certain viruses, such as herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV).Fórmula:C25H41N12O14P3S•NaxPureza:Min. 95%Forma y color:White/Off-White SolidPeso molecular:858.65 g/mol5-Carboxy-2’-deoxycytidine
CAS:Please enquire for more information about 5-Carboxy-2’-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C10H13N3O6Peso molecular:271.23 g/mol6-Amino-4-hydrazino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrazino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a nucleoside phosphoramidite which is used in the synthesis of oligonucleotides. It is a novel modified nucleoside and has antiviral and anticancer activities. 6-Amino-4-hydrazino-1-(b-D ribofuranosyl)-1H pyrazolo[3,4 d]pyrimidine can be used as an activator for 2'-deoxyribonucleotide synthesis and an inhibitor of ribonucleotide synthesis.
Pureza:Min. 95%N6-Benzoyl-8-hydroxy-2'-O-methyladenosine
N6-Benzoyl-8-hydroxy-2'-O-methyladenosine is a nucleoside analogue that inhibits the replication of RNA and DNA. It is a monophosphate, which can be converted to a diphosphate through phosphorylation. N6-Benzoyl-8-hydroxy-2'-O-methyladenosine has been shown to inhibit cancer cells and may have potential for use in antiviral therapy. This compound was synthesized from 2,4,5,6 tetrahydrobenzyl alcohol and 2'-deoxyadenosine. The CAS number for this compound is 79430-89-1.
Pureza:Min. 95%2',3',5'-Tri-O-acetyl-6-azauridine
CAS:2',3',5'-Tri-O-acetyl-6-azauridine is a nucleoside analog for research purposes. The replacement of a carbon atom with a nitrogen atom on the uracil base affects how the molecule interacts with cellular processes. It has the potential to interfere with normal metabolic processes within cells, particularly those related to RNA synthesis. Due to its ability to disrupt cell growth, it could be studied for any potential antiviral or antitumor properties.
Fórmula:C14H17N3O9Pureza:Min. 95%Forma y color:PowderPeso molecular:371.3 g/molN4-Acetyl-5-methylcytidine
CAS:N4-Acetyl-5-methylcytidine is a novel, modified nucleoside with antiviral and anticancer properties. It is an activator of RNA polymerase II and inhibits DNA synthesis by inhibiting the activity of DNA polymerase. N4-Acetyl-5-methylcytidine has been shown to be effective in treating cancers that are sensitive to chemotherapy, such as lymphomas, myelomas, and leukemias. It can be used as a substitute for cytosine in the synthesis of oligonucleotides and phosphoramidites.
Pureza:Min. 95%5-Ethynyl-2'-O-methyluridine triphosphate
5-Ethynyl-2'-O-methyluridine triphosphate is a novel nucleoside that contains a methyl group at the 5 position of the uracil ring. It is an antiviral agent for use in the treatment of HIV, herpes simplex virus, cytomegalovirus, and influenza virus infections. 5-Ethynyl-2'-O-methyluridine triphosphate is also used as a precursor to synthesize DNA and RNA. This compound has been shown to have anticancer properties against breast cancer cells.
Pureza:Min. 95%1,3-Dimethylpseudouridine
CAS:1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applications
Fórmula:C11H16N2O6Pureza:Min. 95%Forma y color:PowderPeso molecular:272.25 g/molRef: 3D-ND162827
Producto descatalogado7-Allyl-7,8-dihydro-8-oxoguanosine
CAS:Agonist of toll-like receptors TLR7
Fórmula:C13H17N5O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:339.3 g/mol2'-Deoxy-4'-thiouridine
CAS:2'-Deoxy-4'-thiouridine (2dT) is a synthetic purine nucleoside analogue that has antiviral activity against herpes simplex virus and hepatitis B virus. It is a lead compound for the development of therapeutic agents for human immunodeficiency virus type 1 and varicella, and it has potential applications in the treatment of renal toxicity. 2dT inhibits viral replication by inhibiting viral thymidine kinase, which converts 2dT to 2'-deoxy-4'-thioguanosine monophosphate (2'TGMP). The 2'TGMP inhibits intracellular phosphorylation reactions necessary for DNA synthesis and cell division. This inhibition leads to death of the infected cells.
Fórmula:C9H12N2O4SPureza:Min. 95%Peso molecular:244.27 g/molCytidine 5'-triphosphate disodium salt
CAS:Please enquire for more information about Cytidine 5'-triphosphate disodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C9H14N3Na2O14P3Pureza:Min. 97 Area-%Peso molecular:527.12 g/molAdenosine 5'-triphosphate disodium salt hydrate
CAS:Adenosine 5'-triphosphate disodium salt hydrate (ATP 2Na) is a nucleoside triphosphate acting as the essential part of energy storage and metabolism in vivo. It plays a crucial role in many biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function, often described as the "molecular unit of currency" for intracellular energy transfer.
Fórmula:C10H14N5Na2O13P3·xH2OPureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:551.14 g/mol4-Thiouridine-5'-triphosphate sodium salt - aqueous solution
CAS:4-Thiouridine-5'-triphosphate sodium salt - aqueous solution (4TUTP) is an analog of uridine and can be used as a template for the synthesis of single-stranded DNA. 4TUTP has been shown to have a high affinity for dsDNA, allowing it to form a ternary complex with DNA polymerase and single-stranded DNA template. 4TUTP can also be used to prepare samples for profiling experiments or other molecular studies. It is reactive, so should be handled with caution in order to avoid unwanted crosslinking. 4TUTP may also be used in chloroplast research.Fórmula:C9H15N2O14P3S·xNaPureza:Min. 95 Area-%Forma y color:Clear LiquidPeso molecular:500.20 g/molRef: 3D-NT34810
Producto descatalogado9-(3'-O-Methyl-b-D-xylofuranosyl)adenine
9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a synthetic nucleoside that is an activator of viral DNA polymerase. 9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a novel nucleoside that has been shown to be active against both DNA and RNA viruses. This compound also has anticancer activity. 9-(3'-O-methyl-β-D-xylofuranosyl)adenine is the phosphorylated form of adenine and has high purity and quality. The CAS number for this product is 53110-86-2.
Pureza:Min. 95%2',3'-Dideoxy-6-thio-inosine
CAS:2',3'-Dideoxy-6-thio-inosine is a nucleoside analog that is used in vitro for the investigation of viral replication. 2',3'-Dideoxy-6-thio-inosine is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) infection, and has been shown to inhibit the synthesis of viral dna. The in vitro activity of this drug against HIV has been shown to be greater than 200 times more potent than zidovudine or didanosine. 2',3'-Dideoxy-6-thio-inosine also inhibits the growth of some cell lines, including those derived from infected T cells, indicating that it may have cytocidal effects.
Fórmula:C10H12N4O2SPureza:Min. 95%Peso molecular:252.29 g/mol5'-Amino-5'-deoxy-2'-O-methyluridine
5'-Amino-5'-deoxy-2'-O-methyluridine is a novel nucleoside analog with antiviral and anticancer properties. 5'-Amino-5'-deoxy-2'-O-methyluridine is an activator of the immune system, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase. This drug has shown activity against a variety of human tumor cell lines in vitro and in vivo. 5'-Amino-5'-deoxy-2'-O-methyluridine also inhibits the growth of several bacterial strains, including methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium avium complex.
Pureza:Min. 95%2,2'-Anhydro-5'-O-toluoyluridine
2,2'-Anhydro-5'-O-toluoyluridine is a synthetic nucleoside analog that is used as an antiviral agent for the treatment of herpes simplex virus. It activates ribonucleotide reductase and inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 2,2'-Anhydro-5'-O-toluoyluridine has been shown to be active against colon cancer cells in vitro and in vivo. This drug has also been shown to inhibit the growth of certain types of leukemia cells and may be useful in treating patients with chronic myeloid leukemia.
Fórmula:C17H16N2O6Pureza:Min. 95%Peso molecular:344.32 g/mol3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole
CAS:3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole is a nucleoside analog that is an antiviral and anticancer agent. It is a monophosphate, which has been shown to inhibit the replication of DNA by binding to the enzyme DNA polymerase. 3-Cyanovinyl-9-(5’-O-DMT-2’-deoxyribofuranosyl)carbazole also inhibits protein synthesis and cell division by preventing the production of proteins vital for cell division. This drug has shown high purity and quality, as well as novel properties.
Fórmula:C41H36N2O5Pureza:Min. 95%Peso molecular:636.74 g/molPolyinosinic-polycytidylic acid sodium salt
CAS:Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure. PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes. We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products.
For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Fórmula:(C10H13N4O8P)x•(C9H14N3O8P)x•NaxForma y color:White PowderRef: 3D-TP36521
Producto descatalogado6-Azauridine
CAS:Inhibitor of uridine monophosphate synthase
Fórmula:C8H11N3O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:245.19 g/mol3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine
CAS:3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine is a monophosphate nucleoside of cytidine. It is a phosphoramidite building block for the synthesis of DNA, an antiviral and anticancer agent. 3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine has been shown to inhibit the replication of HIV and herpes simplex virus (HSV) in cell cultures and to induce apoptosis in cancer cells by inhibiting protein synthesis and inducing oxidative stress. This nucleoside is synthesized from deoxythymidine 5' phosphate using phosphorus pentoxide as oxidizing agent, followed by a reaction with toluene. The novel 3'-deoxy-3'-fluoro-5'-O-toluoylcytidine can be used as an activator for other modified nucleotides in DNA synthesis or as scaffold for the
Pureza:Min. 95%N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine
N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is a modified nucleoside with antiviral activity. This compound is synthesized by a modified method that avoids the use of phosphoramidites, which are usually used to synthesize nucleosides. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is an activator of viral RNA polymerase and has been shown to be active against HIV and herpes simplex virus type 1.
Pureza:Min. 95%2'-Deoxy-2'-fluoro-L-uridine
CAS:2'-Deoxy-2'-fluoro-L-uridine is a synthetic nucleoside analog of uridine where the sugar is both fluorinated at the 2' position and in the L-configuration, which is the mirror image of naturally occurring D-nucleosides. This modification makes it structurally distinct and biologically significant for certain applications in drug development and biochemical research.
Fórmula:C9H11FN2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:246.2 g/molRef: 3D-ND02886
Producto descatalogadoN6-Benzoyl-2'-O-methyladenosine
CAS:N6-Benzoyl-2'-O-methyladenosine is a novel nucleoside that has been synthesized by chemical modification of adenosine. It is an activator of the ribonucleotide reductase enzyme and is currently being studied as an anticancer and antiviral agent. N6-Benzoyl-2'-O-methyladenosine has shown antitumor activity against human breast cancer cells in vitro and in vivo, inhibiting tumor growth. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and type 2 (HSV2).
Fórmula:C18H19N5O5Peso molecular:385.37 g/mol2’-Deoxy-2’-fluoro-N3-(2S)-[2-(tert-butoxycarbonyl)-amino-3-carbonyl]propyluridine
2’-Deoxy-2’-fluoro-N3-(2S)-[2-(tert-butoxycarbonyl)-amino-3-carbonyl]propyluridine is a nucleoside, modified with fluorine at the 2’ position. It is an activator of phosphoramidites in the synthesis of DNA and RNA. This product has shown anticancer activity in vitro. 2'DFNAPU has also been shown to inhibit the replication of HIV virus and herpes simplex virus type 1 in cell culture, which may be due to its ability to inhibit viral DNA polymerase.
Pureza:Min. 95%3'-Amino-5'-O-benzyl-3'-deoxy-D3-thymidine
Producto controlado3'-Amino-5'-O-benzyl-3'-deoxy-D3-thymidine is a novel antiviral agent that inhibits the replication of retroviruses. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The drug has been shown to inhibit DNA and RNA synthesis in vitro. 3'-Amino-5'-O-benzyl-3'-deoxy-D3-thymidine is also being studied for its anticancer properties.
Fórmula:C17H18N3O4D3Pureza:Min. 95%Peso molecular:334.39 g/mol2'-C-Methyl-6-S-methyl-6-thioinosine
CAS:2'-C-Methyl-6-S-methyl-6-thioinosine is a modified nucleoside that can be used as an antiviral and anticancer agent. It has been shown to activate the immune system by inducing cytokine production, which leads to increased cytotoxicity against tumor cells. 2'-C-Methyl-6-S-methyl-6-thioinosine has also been shown to inhibit DNA synthesis and induce apoptosis in cancer cells. This product is of high purity and quality, with a CAS number of 172722-76-8.
Pureza:Min. 95%5-(Azidomethyl)uridine
CAS:5-(Azidomethyl)uridine (5-AZA-U) is a cytosolic nucleoside analog that inhibits the replication of herpes simplex virus type 1 (HSV-1). It is resistant to degradation by cellular nucleases and is fluorescent, making it a clickable substrate for microscopy. 5-AZA-U has been shown to inhibit the transcription of viral DNA and the synthesis of viral proteins in mammalian cells. This drug has also been shown to be effective against cancer and hepatitis B virus (HBV). 5-AZA-U can be used as an antiviral agent because of its ability to inhibit the posttranscriptional gene expression of HSV-1. 5-(Azidomethyl)uridine is also an analog of uridine, which can be used to study intracellular signaling pathways that regulate proliferation, differentiation, or apoptosis in mammalian cells.
Fórmula:C10H13N5O6Pureza:Min. 95%Forma y color:PowderPeso molecular:299.24 g/molN6-Propargyladenosine-5'-triphosphate sodium salt
N6-Propargyladenosine-5'-triphosphate sodium salt is a phosphoramidite that is useful in the synthesis of oligodeoxyribonucleotides and DNA. This novel nucleotide has been shown to be an activator for mammalian cells and to inhibit tumor growth in mice. N6-Propargyladenosine-5'-triphosphate sodium salt is synthesized by reacting propargylamine with ATP, which produces a novel nucleotide with anti-cancer properties.
Fórmula:C13H18N5O13P3Pureza:Min. 95%Peso molecular:545.23 g/mol4’-Cyanouridine
CAS:4’-Cyanouridine is a nucleoside that is used in the synthesis of DNA and RNA. It is often used as a precursor in the production of phosphoramidites and nucleosides, which are important for DNA synthesis. 4’-Cyanouridine can be used to inhibit viral replication by blocking the activity of reverse transcriptase, an enzyme required for the synthesis of viral DNA. 4’-Cyanouridine can also be used to treat cancer cells by preventing the growth of cells. This compound has been shown to activate RNA polymerase II, which is required for protein synthesis and cell division. The high purity and novel nature of this product make it ideal for use in research laboratories or other specialized settings where high quality products are required.
Pureza:Min. 95%9-(2’-Deoxy-2’-fluoro-arabinofuranosyl)adenine 5’-triphosphate triethyl ammonium salt
Ai Product Descriptions 50 Creative
Pureza:Min. 95%4’-C-Methyl-2-thiouridine
CAS:4’-C-Methyl-2-thiouridine is an activator that has anticancer properties. It is a modified nucleoside with antiviral and antifungal activities, which has been shown to inhibit the growth of human tumor cells in vitro. 4’-C-methyl-2-thiouridine is able to inhibit viral replication in vitro and has been shown to be active against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). Interestingly, this compound was found to have no effect on the intracellular levels of thymidine kinase or on cellular DNA synthesis.
Fórmula:C10H14N2O5SPureza:Min. 95%Peso molecular:274.29 g/mol8-Aza-N6-benzoyl-7-deaza-2'-deoxy-5'-O-DMT-adenosine
CAS:8-Aza-N6-benzoyl-7-deaza-2'-deoxy-5'-O-DMT-adenosine is a nucleoside analog that has been modified by replacing the ribose moiety with deoxyribose. This modification increases its stability in vivo and in vitro. 8-Aza-N6-benzoyl-7-deaza-2'-deoxy-5'-O-DMT adenosine is an activator of DNA polymerase, which can be used to synthesize DNA. It is also an antiviral agent, active against herpes simplex virus type 1 and 2, vaccinia virus, and cytomegalovirus. This compound has shown promising anticancer activity against human breast cancer cells grown in culture.
Fórmula:C38H35N5O6Pureza:Min. 95%Peso molecular:657.71 g/mol3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution
CAS:3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is an azidothymidine (AZT) analog that inhibits HIV replication. AZT is a nucleoside reverse transcriptase inhibitor that blocks the progression of HIV by preventing the virus from duplicating its DNA. This product has been shown to be effective in treating AIDS and related diseases, as well as other infectious diseases such as hepatitis B and C. 3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is often used in combination with other drugs to increase their efficacy. It has also been shown to be an effective chemotherapeutic agent against cancer cells.
Fórmula:C10H14N5O7P·xLiPureza:Min. 95%Peso molecular:347.22 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite
N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is an anticancer agent that acts by inhibiting the formation of DNA and RNA. It is a nucleoside analogue that has been modified to contain a benzoyl group at the 2' carbon atom, which leads to increased cytotoxicity. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-toluoylcytidine 3'-CE phosphoramidite is a synthetic nucleoside analogue with novel properties. It inhibits the synthesis of DNA and RNA in cells, which may be due to its ability to inhibit DNA polymerases and ribonucleases.
Fórmula:C39H54N5O8PSiPureza:Min. 95%Peso molecular:779.95 g/molN′-[9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
CAS:Please enquire for more information about N′-[9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C13H17FN6O4Pureza:Min. 95%Peso molecular:340.31 g/molN6-Acetyl-2',3',5'-tri-O-acetyl-8-hydroxyadenosine
N6-Acetyl-2',3',5'-tri-O-acetyl-8-hydroxyadenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator with antiviral and anticancer properties, as well as various other biological activities. The CAS number for this product is 91359-02-2. The purity of this product ranges from 99% to 100%. This chemical has not been previously synthesized and has not been modified by any substituents or moieties.
Fórmula:C18H21N5O9Pureza:Min. 95%Forma y color:PowderPeso molecular:451.39 g/molRef: 3D-NA08462
Producto descatalogado2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite is an anticancer nucleoside, which is used as a building block to synthesize DNA and RNA. The compound has been shown to be effective against HIV and herpes simplex virus. It also has antiviral effects against influenza A virus, cytomegalovirus, and Epstein Barr virus.
Fórmula:C48H64N7O7PSiPureza:Min. 95%Peso molecular:910.15 g/mol8-Bromoguanosine
CAS:8-Bromoguanosine (8BrG) is a potent inhibitor of cyclase enzymes that lead to the formation of cyclic guanosine monophosphate (cGMP). It has been shown to inhibit signal pathways, such as those regulated by the G protein-coupled receptor (GPCR), which are activated by the 2-adrenergic receptor. 8BrG has been shown to be effective against C. glabrata and other fungi and has been used in experimental models for infectious diseases.
Fórmula:C10H12BrN5O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:362.14 g/molN2-Isobutyryl-N-trityl-morpholino guanine
CAS:N2-Isobutyryl-N-trityl-morpholino guanine is a synthetic nucleoside analogue. It has been shown to be an activator of ribonucleotide reductase, and it is a potential anticancer agent. N2-Isobutyryl-N-trityl-morpholino guanine has also been shown to inhibit the replication of DNA and RNA viruses. This compound is being studied for its possible use in the treatment of HIV infection, as well as other viral infections that affect the central nervous system.
Pureza:Min. 95%2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt
CAS:2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt is a nucleoside analog of Adenosine-5'-triphosphate (ATP), a key player in cellular energy transfer. 2'(3')-O-(4-Benzoyl)benzoyl has been added to this molecule as well as a triethylammonium salt which helps to increase the stability of the molecule in solutions. 2'(3')-O-(4-Benzoyl)benzoyladenosine-5'-triphosphate triethylammonium salt has potential use as a tool for understanding how cells use ATP and how changes to ATP affect cellular processes. Other possible uses are in the study of how ATP interacts with enzymes.
Fórmula:C24H24N5O15P3·C6H15NPureza:Min. 75 Area-%Forma y color:White PowderPeso molecular:816.58 g/mol4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxylic acid
CAS:4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxylic acid (4AP) is a bioactive molecule that is used for the prophylaxis and/or treatment of viruses, such as influenza virus. It is also found in plants and is an intermediate metabolite in lysine conjugation reactions. 4AP may be used to inhibit viral infections by blocking viral protein synthesis at the ribosome level, inhibiting viral RNA polymerase, or by interfering with the assembly of virion components. 4AP has been shown to have antihypertensive properties and may have other therapeutic effects on diabetes and obesity.
Fórmula:C12H14N4O6Pureza:Min. 95%Forma y color:PowderPeso molecular:310.26 g/molN1,N2,N2-Trimethyl-psi-isocytidine
N1,N2,N2-Trimethylpsi-isocytidine is a novel nucleoside analog that has antiviral, anticancer, and immunosuppressive activities. It is an activator of diphosphate kinase and inhibits the formation of deoxyribonucleotides in DNA synthesis. N1,N2,N2-Trimethylpsi-isocytidine is a modified form of cytidine that contains three methyl groups. This agent has been shown to be active against human leukemic cells and can be used for the treatment of cancer and HIV infections.
Pureza:Min. 95%Adenosine-5'-O-diphosphoribose phosphate
CAS:Potential metabolite of NADP+
Fórmula:C15H24N5O17P3Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:639.3 g/molRef: 3D-NA63573
Producto descatalogado3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine
3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is a phosphoramidite, which is an intermediate in the synthesis of nucleosides. It is a novel deoxyribonucleoside that has been modified to include a methyl group at the 5' position. 3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is often used as an activator for DNA polymerases and ribonucleases, as well as for the synthesis of ribonucleosides. This product has shown anticancer activity by inhibiting RNA synthesis.
Pureza:Min. 95%Peso molecular:227.22 g/mol2’C-Methyl-2-thiouridine
CAS:2’C-Methyl-2-thiouridine is a novel nucleoside phosphoramidite that has been synthesized to serve as an activator for DNA polymerases. 2’C-Methyl-2-thiouridine is a potent antiviral agent that inhibits the replication of the hepatitis C virus in vitro. It also has antiproliferative effects against certain cancer cells and can be used as an anticancer drug. 2’C-Methyl-2-thiouridine contains a methylated thiol group, which confers a high degree of resistance to degradation by thiols, including glutathione (GSH). This compound is stable to hydrolysis and may be used in the synthesis of deoxyribonucleosides or monophosphate nucleotides.
Pureza:Min. 95%8-Bromoguanosine-5'-monophosphate
CAS:8-Bromoguanosine-5'-monophosphate (8BrGMP) is a nucleotide analog that modulates the expression of genes involved in circulatory and metabolic processes. 8BrGMP has been shown to be effective in clinical studies, including neonates with hypoxemia or low blood pressure. It also has a dose-dependent effect on the newborn's circulation and blood pressure, and can be used to treat neonatal transition. 8BrGMP is an advance in neonatal care due to its ability to improve oxygenation and promote better cardiovascular stability.
Fórmula:C10H13BrN5O8PPureza:Min. 95%Peso molecular:442.12 g/molStavudine 5'-triphosphate sodium salt - 100 mM aqueous solution
Stavudine 5'-triphosphate sodium salt is a modified nucleoside analog with antiviral and anticancer properties. It is a phosphoramidate of stavudine, which has been modified by the replacement of the L-cysteine moiety with a 2-thiophenecarboxamide group. The novel chemical structure of stavudine 5'-triphosphate sodium salt leads to higher solubility in water than other analogues and improved pharmacokinetics. Stavudine 5'-triphosphate sodium salt is an activator for the synthesis of DNA, RNA, and protein. It also inhibits viral replication by interfering with viral DNA polymerase and ribonucleotide reductase, which are essential enzymes for viral replication.Fórmula:C10H17N2O13P3·xNaPureza:Min. 95 Area-%Forma y color:Clear LiquidPeso molecular:466.17 g/mol2,4-Dithiouridine
CAS:2,4-Dithiouridine is a nucleoside for use in a variety of applications
Fórmula:C9H12N2O4S2Pureza:Min. 95%Forma y color:PowderPeso molecular:276.33 g/molRef: 3D-ND10281
Producto descatalogadoAllopurinol riboside
CAS:Allopurinol riboside is a hydroxyl analog of allopurinol. Allopurinol riboside has minimal toxicity in tissue culture and exhibits no cytotoxicity in human serum. It is a potent inhibitor of microbial infection, including infections caused by Hepatitis C virus (HCV), Leishmania amazonensis, and Mycobacterium tuberculosis. Allopurinol riboside binds to adenine nucleotide and inhibits the synthesis of purines, which are necessary for DNA replication. This binding also inhibits the production of ATP, leading to cell death. In addition, allopurinol riboside inhibits the growth of human macrophages in vitro by inhibiting protein synthesis. Allopurinol riboside may be useful for treating HCV-induced liver disease or leishmaniasis.
Fórmula:C10H12N4O5Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:268.23 g/mol3'-O-Amino-2'-deoxycytidine
CAS:3'-O-Amino-2'-deoxycytidine (3'-AAC) is an activator nucleoside that has antiviral and anticancer properties. It can be used with other anticancer agents such as doxorubicin, methotrexate, and 5-fluorouracil to increase the efficacy of these compounds. 3'-AAC is a phosphoramidite monophosphate that can be used in the synthesis of oligodeoxynucleotides. This product is also a novel chemical entity that has not been previously described in any publication or patent application.
Fórmula:C9H14N4O4Pureza:Min. 95%Peso molecular:242.23 g/mol3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine
3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine is a synthetic nucleoside that has antiviral activity. It is a modified nucleoside that contains a monophosphate group, which makes it an activator of DNA polymerase. 3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine is novel because it contains an acetyl group at the 3' position and a silyl ether on the 2' oxygen atom. 3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro -5 -methyluridine has CAS No. 62768‑36‑3 and is available in high purity.Pureza:Min. 95%N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine
CAS:N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a nucleoside monophosphate with antiviral and anticancer activity. It is used as an activator for the synthesis of oligodeoxynucleotides and may be used in the treatment of herpes zoster, AIDS, or cancer. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine has a novel structure that is modified from natural nucleosides and has been shown to have high purity.
Pureza:Min. 97.0 Area-%Forma y color:PowderPeso molecular:445.60 g/molRef: 3D-NB08718
Producto descatalogado5-(Aminomethyl)-2-thiouridine
CAS:5-(Aminomethyl)-2-thiouridine is a bifunctional molecule that can be used in chromatography and as a precursor for the epigenetic modifications of DNA. 5-(Aminomethyl)-2-thiouridine has been shown to have an effect on the methyltransferase pathway, which is involved in the epigenome. This molecule has also been shown to affect the growth rate of bacteria in vitro.
Fórmula:C10H15N3O5SPureza:Min. 95%Peso molecular:289.31 g/mol3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
CAS:3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It has shown to be effective against a variety of viruses including HIV-1, herpes simplex virus type 1, influenza A virus, vaccinia virus, and vesicular stomatitis virus. 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt also inhibits the growth of cancer cells in vitro. This drug is a modified nucleoside with a phosphoramidite backbone and a 3'-azido group at one end. The other end contains a beta D glucuronic acid moiety. The modifications allow for the inhibition of DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA chains.
Fórmula:C16H20N5NaO10Pureza:Min. 95%Forma y color:PowderPeso molecular:465.35 g/molRef: 3D-NA06316
Producto descatalogadoPolyinosinic acid tripotassium salt
CAS:Polyinosinic acid is a single stranded RNA analog which is combined with polycytidylic acid (poly C) to form a stable duplex structure known as Polyinosinic acid-polycytidylic acid (Poly I:C). PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes. We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products.
For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Pureza:Min. 95%Ref: 3D-TP65775
Producto descatalogado2'-Deoxy-N6-methyladenosine
CAS:2'-Deoxy-N6-methyladenosine (2DMA) is a nucleoside that has been found to inhibit the phosphorylation of p2y receptors in rat kidney cells. 2DMA inhibits the production of collagen, which may have a matrix effect on cells. Studies have shown that 2DMA can be used as a sample preparation reagent for nuclear DNA. It has also been shown to be effective at inhibiting transcription and replication of human mitochondrial DNA.
Fórmula:C11H15N5O3Pureza:Min. 95%Forma y color:White PowderPeso molecular:265.27 g/molInosine-3',5'-cyclic-monophosphate sodium
CAS:Inosine-3',5'-cyclic-monophosphate sodium (cIMP) is a metabolite of inosine and is generated by the enzyme inosine monophosphate cyclohydrolase. cIMP has been shown to be related to colorectal adenocarcinoma, cancer, and body mass index. It has also been implicated in the diagnosis of cancer and infectious diseases. cIMP is involved in energy metabolism and DNA synthesis, which are important for the progression of renal cell cancer. In addition, it has been shown that cIMP can function as a biomarker for prognosis when used with multivariate logistic regression.Fórmula:C10H11N4O7P·NaPureza:Min. 95%Peso molecular:353.18 g/molRef: 3D-NI170529
Producto descatalogado3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt
Producto controlado3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt is a novel antiviral nucleoside phosphoramidite that has been shown to be an effective activator in the synthesis of diphosphate and triphosphate analogs. The novel antiviral nucleoside phosphoramidite was synthesized from 3'-azido-3'-deoxythymidine, methyl bromoacetate and sodium hydroxide in methanol at room temperature. It is structurally similar to the natural nucleosides, deoxyribonucleosides and ribonucleosides with modifications on the sugar moiety and phosphate group. This compound is a high quality synthetic material for use in pharmaceutical research, as an anticancer agent and as a potential antiviral drug.Fórmula:C16H17D3N5NaO10Pureza:Min. 95%Forma y color:PowderPeso molecular:468.36 g/molRef: 3D-NA04586
Producto descatalogado2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine (dAraMP) is a novel nucleoside analogue that was synthesized and characterized. It has been shown to inhibit the growth of cancer cells in vitro. dAraMP is a monophosphate analogue of 2,6-diamino-9-(2'-deoxy-b-D-ribofuranosyl)purine (dAraP). The modified phosphoramidite approach used in its synthesis yielded high purity and yields. This product is also available as a diphosphate analogue of 2,6 diamino 9-(2'-amino 2'-deoxy b D ribofuranosyl) purine (dAMP). The diphosphate form of this product has been shown to be an activator for DNA polymerase.Fórmula:C10H15N7O3Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:281.28 g/molRef: 3D-ND06322
Producto descatalogado2-Hydroxyaminoadenosine
CAS:2-Hydroxyaminoadenosine (2-HAA) is a novel nucleoside that is used as an activator of ribonucleotide reductase. It has been shown to be effective against cancer cells in vitro and in vivo. 2-HAA also inhibits the synthesis of viral DNA, which may be due to its ability to inhibit the ribonuclease activity of the virus. 2-HAA has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1).
Fórmula:C10H14N6O5Pureza:Min. 95%Peso molecular:298.26 g/molEthyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS:Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.
Fórmula:C8H8F3N3O2Pureza:Min. 95%Peso molecular:235.16 g/molN4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine
N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.
Fórmula:C21H23N3O7Pureza:Min. 95%Peso molecular:429.43 g/mol3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
CAS:3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.
Fórmula:C22H39N5O6Si2Pureza:Min. 95%Peso molecular:525.75 g/molRef: 3D-NT16564
Producto descatalogado8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.Fórmula:C10H17N6O13P3·xNaPureza:Min. 95%Peso molecular:522.2 g/molRef: 3D-NA12011
Producto descatalogado3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine
CAS:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.
Fórmula:C23H17Cl2FN2O7Pureza:Min. 95%Peso molecular:523.29 g/molRef: 3D-ND22464
Producto descatalogadoNonadecanoyl coenzyme A
CAS:Nonadecanoyl coenzyme A is a fatty acid that is produced by the bovine liver and has been shown to have anabolic effects. Nonadecanoyl CoA is involved in the synthesis of various lipids, such as phospholipids, cholesterol, and glycolipids. It also plays a role in biosynthesis of fatty acids and in regulating ATP production. Nonadecanoyl CoA is synthesized from acetate by the enzyme acetyl-CoA carboxylase (ACC). ACC catalyzes the conversion of acetyl-CoA to malonyl-CoA, which can then be used for fatty acid synthesis. Nonadecanoyl CoA has been found to play an important role in regulating mitochondrial function through its ability to activate long-chain acyl-CoAs desaturase (LCAD). LCAD converts long-chain acyl-CoAs into their corresponding dicarboxylic acids.
Fórmula:C40H72N7O17P3SPureza:Min. 95%Peso molecular:1,048.02 g/mol3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt
Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C13H22N3O14P3•(C6H15N)xPureza:Min. 99 Area-%Forma y color:PowderPeso molecular:537.25 g/molPyrimidine-4-carboxylic acid hydrazide
CAS:Pyrimidine-4-carboxylic acid hydrazide (PCAH) is an antimycobacterial agent that inhibits the growth of Mycobacterium tuberculosis and other related species. PCAH is a ligand that binds to redox active metal ions, forming a supramolecular complex. The carboxyl group on PCAH reacts with the hydroxide ion in the presence of water to produce hydrogen peroxide, which in turn oxidizes the mycolic acids in the cell wall of M. tuberculosis, leading to cell death. The pyridine ring on PCAH is nucleophilic and can react with nucleophiles such as thiols or amines, which are found in proteins or peptides. This reaction results in nucleophilic substitutions, which inhibit bacterial protein synthesis and lead to cell death.Fórmula:C5H6N4OPureza:Min. 95%Peso molecular:138.13 g/molRef: 3D-NP57376
Producto descatalogado3'-Deoxy-L-thymidine
CAS:3'-Deoxy-L-thymidine is a nucleoside analog that inhibits HIV replication by interfering with the synthesis of viral DNA. The drug binds to the enzyme thymidine phosphorylase, which converts thymidine into deoxyuridine monophosphate, and prevents conversion of deoxyuridine to deoxythymidine monophosphate. This leads to inhibition of both DNA synthesis and the production of RNA. 3'-Deoxy-L-thymidine has dose-limiting toxicity at high doses and is not active against other viruses such as herpes simplex virus or cytomegalovirus. It is metabolized in the liver by enzymes such as 5-fluorocytosine, which converts it into its active form, 5-fluorouracil.
Fórmula:C10H14N2O4Pureza:Min. 95%Peso molecular:226.23 g/mol5'-O-tert-Butyldimethylsilylthymidine
CAS:5'-O-tert-Butyldimethylsilylthymidine is a nucleoside that is used for the synthesis of oligoribonucleotides. It can be prepared by treating 5'-O-tert-butyldimethylsilylthymidine with alkyl bromides in the presence of microwaves and catalytic amounts of a base such as sodium methoxide. The product is purified by vacuum distillation or column chromatography and can be hydrolyzed to uridine, which has been shown to have anti-inflammatory properties. 5'-O-tert-Butyldimethylsilylthymidine can also be converted into deoxyribose through the use of ultrasound.Fórmula:C16H28N2O5SiPureza:Min. 95%Peso molecular:356.5 g/molRef: 3D-NB08945
Producto descatalogado5'-O-DMT-2'-O-(2-methoxyethyl)uridine
CAS:5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.
Fórmula:C33H36N2O9Pureza:Min. 95%Peso molecular:604.65 g/mol8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione
CAS:8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is a monophosphate nucleotide analog that inhibits viral DNA polymerases. It is a novel and high quality nucleoside phosphoramidite. 8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is synthesized from 2'-deoxyribonucleosides and modified ribonucleosides. The CAS number for the compound is 35763855 2.
Fórmula:C10H12N4O5Pureza:Min. 95%Peso molecular:268.23 g/molRef: 3D-ND145594
Producto descatalogadoCytidine 5'-monophosphate sodium salt
CAS:Cytidine 5'-monophosphate sodium salt is a nucleotide that is found in RNA and DNA. Cytidine 5'-monophosphate sodium salt is an intermediate in the biosynthesis of uridine, choline, and saccharose. It also plays an important role in the immune system as it can be a precursor for immunoglobulins. The reaction rate of cytidine 5'-monophosphate sodium salt with lipase has been shown to be constant at pH 7.5-8.0 and 37°C. This product has been shown to have emulsifying properties by forming micelles with water-immiscible solvents such as hexane or heptane, which may be due to its ability to form hydrogen bonds with other molecules such as saccharose or guanosine. Cytidine 5'-monophosphate sodium salt can also be used as a chromatographic material for separating saccharose from other sugars
Fórmula:C9H14N3O8P·xNaPureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:323.2 g/mol5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid
CAS:5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is a pyrimidine derivative that inhibits protein kinases. The compound has been shown to inhibit the activity of protein kinase C, which is involved in mediating inflammatory responses, and phosphorylation of the insulin receptor substrate 1. 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is an efficient inhibitor of kinases and can be used as a lead compound for the development of new compounds with therapeutic potential.Fórmula:C6H5BrN2O2SPureza:Min. 95%Peso molecular:249.09 g/molRef: 3D-NB44268
Producto descatalogado3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS:3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (BUdR) is an antiviral agent that is used in the synthesis of DNA and RNA. BUdR is a modified phosphoramidite that is activated with diphosphate. It has a high quality, high purity, and a novel structure. BUdR has been shown to have anticancer properties as well as inhibitory effects on HIV production in cells.
Fórmula:C16H27N5O4SiPureza:Min. 95%Peso molecular:381.51 g/molRef: 3D-NA08679
Producto descatalogadoN6-Benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å
N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is a novel nucleoside with antiviral activity. It is synthesized by the condensation of 2'-deoxyadenosine monophosphate and 3'-Q linker CPG 1000 Å. The molecular weight of N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is 878.36 g/mol, and its CAS number is 628674-06-4. This substance has antiviral activity against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). N6-benzoyl-2'-deoxy-5'-O-DMT adenosine can be used as an anticancer drug because it inhibits the growth
Pureza:Min. 95%Ref: 3D-NB11617
Producto descatalogadoUridylyl-3'-5'-cytidine ammonium salt
Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.
Fórmula:C18H27N6O13PPureza:Min. 95%Peso molecular:566.41 g/mol3'-O-Methyl-5'-guanylic acid
CAS:3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.
Fórmula:C11H16N5O8PPureza:Min. 95%Peso molecular:377.25 g/mol5-Methyl-2',3'-stannyluridine
5-Methyl-2',3'-stannyluridine is a nucleoside analog that is a potent inhibitor of viral replication and can be used for the treatment of HIV. It has been shown to inhibit the activity of RNA polymerase, thereby preventing transcription and replication. 5-Methyl-2',3'-stannyluridine also inhibits DNA synthesis by inhibiting the activity of DNA polymerase. This drug also acts as an antitumor agent and has been shown to inhibit tumor growth in animal models. The high purity of this drug makes it suitable for use in pharmaceutical applications.
5-Methyl-2',3'-stannyluridine is a modified nucleoside that has been modified with a stannyl group at the 2' position on the sugar moiety and an allyl group at the 3' position on the sugar moiety. The phosphoramidites are synthesized from 5-methyl-2',3'-stannylPureza:Min. 95%2'-Deoxy-N6-phenoxyacetyladenosine
CAS:2'-Deoxy-N6-phenoxyacetyladenosine is a cyclic oligonucleotide analog that has been shown to be efficient in inhibiting the replication of RNA. It binds to the RNA polymerase, preventing transcription and replication of the nucleic acid. 2'-Deoxy-N6-phenoxyacetyladenosine is also an effective inhibitor of DNA synthesis and can inhibit the synthesis of proteins by binding to ribosomes. This drug is structurally similar to deoxyadenosine, which is a component of DNA, and it has been shown to be more potent than other analogs.
Fórmula:C18H19N5O5Pureza:Min. 97 Area-%Peso molecular:385.38 g/mol1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole
CAS:1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole is a nucleoside that can be used as an activator for phosphoramidite synthesis. It is also known to have antiviral, anticancer, and antimalarial properties. 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole has been shown to inhibit the proliferation of human leukemia cells in culture. It has also been shown to suppress HIV replication in vitro by inhibiting viral RNA synthesis.Fórmula:C14H17NO3Pureza:Min. 95%Peso molecular:247.3 g/molRef: 3D-ND06396
Producto descatalogado2'-O-Hexylaminoguanosine
2'-O-Hexylaminoguanosine is a modified nucleoside that has antiviral properties. It is an activator of the human immune system and is used to treat cancer. 2'-O-Hexylaminoguanosine inhibits the synthesis of DNA by phosphoramidite addition to the monophosphate form of guanosine, which prevents RNA synthesis and therefore also protein synthesis. It also has anticancer effects by inhibiting the growth of cells in culture.
Pureza:Min. 95%5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium, 100mM aqueous solution
5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.
Fórmula:C12H17N4O13P3•Li4Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:545.97 g/molRef: 3D-NA32075
Producto descatalogado2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation into
Fórmula:C10H12N5O11P3·4LiPureza:Min. 95%Forma y color:PowderPeso molecular:498.91 g/molRef: 3D-ND32077
Producto descatalogadoGuanosine hydrate
CAS:Please enquire for more information about Guanosine hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C10H13N5O5·xH2OPureza:Min. 98 Area-%Peso molecular:283.24 g/molRef: 3D-W-108553
Producto descatalogado2-(3-Methylphenyl)pyrimidine-5-carbaldehyde
CAS:2-(3-Methylphenyl)pyrimidine-5-carbaldehyde is a monophosphate nucleoside analog that can be used as an antiviral drug. It has shown cytotoxic activity against cells with a high DNA content, and it inhibits the synthesis of RNA and DNA. This compound could be useful for the treatment of HIV and other viral diseases.Fórmula:C12H10N2OPureza:Min. 95%Peso molecular:198.22 g/mol3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine
3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.
Fórmula:C32H31FN2O8Pureza:Min. 95%Peso molecular:590.6 g/molRef: 3D-NA08460
Producto descatalogadoN6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS:N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.
Fórmula:C24H23N5O5Pureza:Min. 95%Peso molecular:461.5 g/molRef: 3D-SFA97940
Producto descatalogadoLinoleoyl coenzyme A
CAS:Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.
Fórmula:C39H66N7O17P3SPureza:Min. 95%Peso molecular:1,029.97 g/mol5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione
Ribonuclease is an enzyme that cleaves the phosphodiester backbone of ribonucleotide to produce a 5'-phosphate and a 2'-deoxyribonucleoside. Ribonuclease is an activator that activates the synthesis of ribonucleotides, deoxyribonesucleotides and nucleosides. Ribonuclease has antiviral properties which may be due to its ability to inhibit DNA polymerase by catalyzing the hydrolysis of the 2'-deoxyribose-5'-phosphate bond in DNA. Ribonuclease has also been shown to have anticancer activity, which may be due to its ability to inhibit protein synthesis.
Pureza:Min. 95%Ref: 3D-NT44284
Producto descatalogadoAmmonium 4-nitrobenzoate dihydrate
CAS:Ammonium 4-nitrobenzoate dihydrate is a corrosion inhibitor that prevents the corrosion of metal parts and other materials. It is used in the production of plastics, coatings, adhesives, and lubricants. The corrosion inhibition activity of aminobenzoates can be attributed to their ability to form hydrogen phosphate (HPO) anions as well as their ability to complex with metal ions. The hydration process is also important for the corrosion inhibition activity of ammonium 4-nitrobenzoate dihydrate. This process involves the release of water molecules from the ammonium salt, which provide a protective coating around the metal surface. Ammonium 4-nitrobenzoate dihydrate also has additive properties that are beneficial for other industrial applications such as antistatic agents, surfactants, and stabilizers.
Pureza:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG
2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG is a modified nucleoside, which is synthetically prepared. It is an activator of DNA polymerase and has been shown to be active against human leukemia cells. 2'-Deoxy-5'-O-DMT-N2-isobutyryl Guanosine 3'-lcaa CPG has also been shown to inhibit the replication of the herpes simplex virus type 1 in vitro. The compound is a novel high quality nucleoside phosphoramidite that can be used as a building block in the synthesis of deoxyribonucleosides and modified nucleosides with novel chemical structures.
Pureza:Min. 95%rac-Lamivudine acid
CAS:Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.
Fórmula:C8H9N3O4SPureza:Min. 95%Peso molecular:243.24 g/molRef: 3D-NL27534
Producto descatalogado6-Amino-1-methyluracil
CAS:6-Amino-1-methyluracil is a synthetic drug that is used in the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. It is also used to treat cancer, such as leukemia and in the treatment of bacterial infections. 6-Amino-1-methyluracil inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase. This inhibition prevents DNA replication and transcription, which leads to cell death. 6-Amino-1-methyluracil binds to cellular proteins through its amino group and hydroxyl group, which are not involved in its chemical reactions. 6-Amino-1-methyluracil has shown great promise as a template molecule for the synthesis of new drugs.
Pureza:Min. 95%7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS:7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.
Fórmula:C14H14ClN3Pureza:Min. 95%Peso molecular:259.73 g/mol2-Methylthio-6-chloropurine
CAS:2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.
Fórmula:C6H5CIN4SPureza:Min. 95%Peso molecular:304.11 g/molN6-Acetyl-2'-deoxy-5'-O-DMT-adenosine
N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.
Fórmula:C33H33N5O6Pureza:Min. 95%Peso molecular:595.65 g/molRef: 3D-NA08597
Producto descatalogadoN2-Benzoylguanosine
CAS:N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.
Fórmula:C17H17N5O6Pureza:Min. 95%Forma y color:White to beige solid.Peso molecular:387.35 g/molRef: 3D-NB06331
Producto descatalogado5'-O-Tosylthymidine
CAS:5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Fórmula:C17H20N2O7SPureza:Min. 95%Peso molecular:396.42 g/molRef: 3D-NT10016
Producto descatalogado2',3',5'-Tri-O-acetylinosine
CAS:2′,3′,5′-Tri-O-acetylinosine is a protected form of the nucleoside inosine, with potential for use in the preparation of modified nucleotides and nucleoside analogs.
Fórmula:C16H18N4O8Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:394.34 g/molRef: 3D-NT06708
Producto descatalogado3′-Guanylic acid disodium
CAS:3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.
Fórmula:C10H14N5O8P•Na2Pureza:Min. 95%Peso molecular:409.2 g/molRef: 3D-NG182606
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