Nucleósidos

<p>N6-Benzoyl-5'-O-benzoyl-2'-deoxyadenosine is an antiviral and anticancer compound. It has been shown to be active against a number of viruses, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1, and influenza A virus. It also inhibits DNA polymerase α and β by competitive inhibition, preventing the incorporation of ribonucleotides into DNA. This compound may be used for the treatment of AIDS or as a cytostatic agent for the treatment of leukemia or lymphoma.</p>

<p>3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.</p>

<p>2’-Deoxy-N6-isopentenyladenosine (2’-DIA) is a monophosphate nucleoside that has antiviral properties. It activates DNA polymerase and inhibits tumor proliferation by inhibiting the synthesis of RNA and DNA. 2’-DIA is an analog of adenosine, which is used in the anticancer drug gemcitabine. 2’-DIA is synthesized through the condensation of 6-(2'-deoxyisopentenyl)adenosine with diphosphate. This compound also functions as a ribonucleotide, meaning it can be incorporated into RNA chains to form new proteins.</p>

<p>5-Formyl-2'-O-methylcytidine is a molecule that is involved in cellular processes such as DNA methylation, the addition of a methyl group to the 5 position of a cytosine residue. It has been shown to be an important epigenetic regulator and can be used as a strategy to treat tuberculosis. 5-Formyl-2'-O-methylcytidine is synthesized from guanine, which undergoes conversion into cytosine via enzymatic modification. This process is catalyzed by methyltransferase enzymes and it is usually carried out with S-adenosylmethionine (SAM) as the methyl donor. The product then converts back into guanine through deamination, which can be catalyzed by either adenine phosphoribosyltransferase or adenylate kinase.</p>

<p>The N6-benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that is a potent inhibitor of the human immunodeficiency virus type 1 (HIV-1) and has been shown to be effective against cancer. It is a phosphoramidite nucleoside with high purity and high quality, which can be used as an antiviral agent or an anticancer agent. The chemical name for this compound is 2'-(N6-Benzoyl)-2'-deoxyadenosine 5'-O-(DMT). This product is also known as NBDT, and it has been modified by changing the ribose sugar to DMT. NBDT inhibits viral replication by preventing the formation of DNA from RNA in the reverse transcription process. This process requires two enzymes: HIV reverse transcriptase and DNA polymerase α. The first enzyme, HIV reverse transcriptase,</p>

<p>Please enquire for more information about 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.</p>

<p>9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.</p>

<p>Please enquire for more information about Nicotinic acid-13C6 riboside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl-b-L-ribofuranosyl)-6-chloropurine is a modified nucleoside. It is synthesized by attaching an acetyl group to the 2' position of the sugar moiety and a toluoyl group to the 3' position of the ribose moiety. 9-[2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-toluoyl]-6 chloropurine has been shown to be an activator of RNA polymerase II and III, which are involved in transcription and replication. This drug also has antiviral properties against influenza virus, herpes simplex virus type 1, Epstein Barr Virus (EBV), and HIV as well as anticancer activity against human cells. 9-[2'-O-Acetyl]-6 chlor</p>

<p>5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is a modified nucleoside that can be used as an anticancer drug. It is a high purity, diphosphate, Anticancer, Modified, Phosphoramidites. 5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is synthesized by the phosphorylation of thymidine with oxazaphospholidine. It has been shown to inhibit DNA and RNA synthesis in cancer cells.</p>

<p>5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.</p>

<p>S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.</p>

<p>monophosphate of 2-deoxy-5-hydroxymethyluridine</p>

<p>5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.</p>

<p>3’-Deoxy-3’-fluoro-2-thiouridine is a nucleoside analog that has been modified to have antiviral and anticancer activity. It is an activator of the ribonucleotide reductase enzyme, which is involved in DNA synthesis. 3’-Deoxy-3’-fluoro-2-thiouridine has been used successfully as an antiviral agent against HIV and other viruses, and as an anticancer agent against leukemia. The monophosphate form of this drug has been shown to inhibit DNA replication in vitro.</p>

<p>3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is a synthetic nucleoside analogue that inhibits the synthesis of DNA. It is a monophosphate and diphosphate analog of thymidine, which are incorporated into DNA during replication. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is an activator of RNA polymerase II and inhibits viral replication by inhibiting the function of reverse transcriptase. This drug has been shown to be effective against HIV in vitro and in vivo, as well as herpes simplex virus type 1. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine also has antitumor activity as it inhibits the growth of</p>

<p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is a nucleoside analogue that has been modified to contain an isobutyryl group. It is an activator of the polymerase enzyme, which helps to synthesize DNA. This product can be used in the synthesis of oligonucleotides for use as therapeutic or diagnostic agents.<br>It has anticancer and antiviral activities, due to its ability to inhibit viral replication. This product also has high purity and quality.</p>

<p>2-Methylmercapto-4-oxo-6-aminopyrimidine monohydrate is a chemical substance that is used as an anticancer and antiviral agent. It has been demonstrated to inhibit the proliferation of tumor cells in vitro and in vivo, and to deplete tumor cell lines of the enzyme ribonucleotide reductase, which is essential for DNA synthesis. The compound also inhibits the synthesis of viral nucleic acid. 2MMAP has a novel chemical structure that includes a methyl group attached to one nitrogen atom. This modification increases its affinity for DNA and RNA molecules by binding to the phosphate groups on these molecules.</p>

<p>9-(b-D-Arabinofuranosyl)hypoxanthine is a glycosylated analogue of the incretin hormone glucagon-like peptide-1 (GLP-1). It has been shown to inhibit Streptococcus pyogenes and other bacteria. 9-(b-D-Arabinofuranosyl)hypoxanthine has also been shown to have inhibitory properties against zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant. This drug has not been studied in clinical trials for antiviral prophylaxis or arabinoside. The only known side effects are drug interactions with cyclin D2 and nitrate reductase.</p>

<p>5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a novel nucleoside with the ability to activate ribonucleosides and phosphoramidites. It is a modified nucleoside that has been shown to have anticancer and antiviral properties. 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine also inhibits the synthesis of viral RNA and DNA, which may result in its antiinflammatory properties. 5’-Azido-5’deoxy -2′O methyl -5′ methyl uridine has a CAS number of 187733–73–9.</p>

<p>5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.</p>

<p>3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine is a nucleoside with anticancer activity. It is a novel nucleoside that has been shown to have antiviral and antitumor activities. Research has shown that 3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine inhibits tumor growth in animals without toxicity to the normal cells of the body. This nucleoside also has an effect on DNA and RNA synthesis, which may be due to its ability to inhibit viral replication enzymes.</p>

<p>3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.</p>

<p>5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is a novel synthetic nucleoside with antiviral and antitumor activities. It has been shown to inhibit the activity of the HIV virus by preventing DNA replication. 5'-O-tert-Butyldiphenylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also inhibits the synthesis of RNA and proteins, which can lead to cell death. The compound's high purity and quality are ensured by its CAS number.</p>

<p>2'-O-Methyl-2-thiouridine is a modified nucleoside that is categorized as a mismatched nucleotide. It is found in RNA, where it replaces uridine and acts as a mismatch base. 2'-O-Methyl-2-thiouridine has been shown to stabilize duplex DNA against thermal denaturation by forming triplexes with complementary sequences. It also stabilizes dsDNA against hydrolysis by the enzyme ribonuclease H (RNase H) and has been used in the design of antisense therapeutics. Thermophilic bacteria use this molecule to synthesize their own thymine nucleotides, which are structurally similar to 2'-O-methyl-2-thiouridine. This modification prevents mismatches in their own dna and helps protect them from heat stress. The thermodynamic stability of this molecule has been calculated using an algorithm that takes into account the hybridization free energy, enthalpy change, entropy</p>

<p>5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.</p>

<p>Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.</p>

<p>A potential role in apoptosis and cellular senescence.</p>

<p>Coenzyme and regenerating electron donor in catabolic processes</p>

<p>Cyclopentenyl cytosine 5'-triphosphate sodium salt is a synthetic, activator diphosphate. It is used as a phosphoramidite in the synthesis of DNA and RNA. Cyclopentenyl cytosine 5'-triphosphate sodium salt has been shown to have anticancer and antiviral properties.</p>

<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer potential. It is a modified nucleoside that contains an acetyl group at the 4' position. The 3'-OH group has been replaced by a tertiary butyldimethylsilyl group, which renders the compound resistant to deamination by nucleases. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also shows high purity and high quality.</p>

<p>8-Aza-N6-benzoyl-7-deaza-2'-deoxy-5'-O-DMT-adenosine is a nucleoside analog that has been modified by replacing the ribose moiety with deoxyribose. This modification increases its stability in vivo and in vitro. 8-Aza-N6-benzoyl-7-deaza-2'-deoxy-5'-O-DMT adenosine is an activator of DNA polymerase, which can be used to synthesize DNA. It is also an antiviral agent, active against herpes simplex virus type 1 and 2, vaccinia virus, and cytomegalovirus. This compound has shown promising anticancer activity against human breast cancer cells grown in culture.</p>

<p>Adenosine 5'-O-(3-thiotriphosphate), BODIPY FL thioester sodium salt - 5mM buffered aqueous solution is a novel nucleoside that is synthesized from the corresponding phosphoramidites. This compound is an activator of DNA synthesis in mammalian cells and a potent inhibitor of viral replication. It has antiviral activity against HIV, herpes, and influenza viruses. The molecule can be modified to include different substituents such as fluoro, bromo, or chloro groups and has been shown to have anticancer activity.</p>

<p>Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.</p>

<p>5'-O-p-Anisoylthymidine 3'-CE phosphoramidite is a modified nucleoside with anticancer activity. It is an activator of DNA, and has been shown to inhibit the growth of cells in culture. This compound is a novel monophosphate that has not been previously reported.</p>

<p>1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is a novel antiviral agent that is synthesized from ribonucleosides. It is an activator of the monophosphate form of RNA polymerase and inhibits the synthesis of DNA in cells. This drug has also been shown to be effective against cancer cells and may be useful for treatment of leukemia.</p>

<p>Thymidine-5'-diphosphate trisodium salt is a novel anticancer drug that is structurally modified to resemble thymidine. It has antiviral and antitumor effects and can be used as an antineoplastic agent. Thymidine-5'-diphosphate trisodium salt is a high quality, high purity ribonucleoside that can be used in the synthesis of deoxyribonucleosides and phosphoramidites. This drug has shown activity against various types of cancer cells and is being investigated for its potential use in the treatment of leukemia.</p>

<p>2'-O-Methyl-N6-phenoxyacetyladenosine is a phosphoramidite nucleoside that is used in the synthesis of DNA and RNA. It has antiviral, anticancer, and antiribonucleases properties. The chemical structure of 2'-O-Methyl-N6-phenoxyacetyladenosine is similar to that of adenosine, but contains a methyl group on C2' position and an oxyalkyl group on N6. This compound can be used as a novel anticancer agent and has been shown to have high affinity for the purine receptor, inhibiting cancer cell proliferation by activating the p53 tumor suppressor pathway.</p>

<p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside analog. This compound contains a thymine base, a 2'-fluoro-β-D-arabinofuranose sugar, which alters biological stability and function and benzoyl protecting groups at the 3' and 5' positions, commonly used in nucleoside synthesis to control selective modifications.</p>

<p>1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).</p>

<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is a novel modified nucleoside. It is an antiviral and anticancer agent that has been shown to inhibit the replication of DNA in vitro. It also inhibits the synthesis of RNA and protein, which may contribute to its anti-cancer properties. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-trityladenosine 3'-CE phosphoramidite is synthesized from 2,6,8 trichloroquinoline and 2,3,4 trimethoxybenzaldehyde via a novel process with high purity.</p>

<p>8-Azidoadenosine 5'-monophosphate sodium salt is an azido-conjugated adenosine monophosphate derivative used to introduce a label on oligonucleotides. A click reaction between the azide-functionalised nucleotide and a terminal alkyne-functionalised labelled moiety (with either a fluorophore or biotin) generates a stable conjugate containing a triazole link.</p>

<p>5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid is a neuronal blocker that inhibits the enzyme acetylcholinesterase. It is an efficient inhibitor of AChE and has been shown to be effective in animal models of Alzheimer's disease. The inhibition of AChE by 5'-Adenylic acid monoanhydride with (dichlorophosphonomethyl)phosphonic acid leads to increased levels of acetylcholine, which can stimulate nerve impulses and slow or stop the progression of Alzheimer's disease.</p>

<p>2-Methoxy-9-(b-D-ribofuranosyl)purine (2MeO) is a nucleoside that is structurally similar to adenosine. It has antiviral and anticancer activities, as well as the ability to activate phosphoramidites. The 2MeO molecule consists of a modified 9-mer ribofuranose phosphate, which can be synthesized from 2-deoxyribofuranose phosphate by selective oxidation. 2MeO has been shown to inhibit the growth of tumor cells in vitro and in vivo, and also inhibits the replication of DNA and RNA viruses. This drug is considered novel because it does not exist naturally in any organism.</p>

<p>5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is a modified nucleoside that has been used as an anticancer agent and antiviral and antifungal agent. It has been shown to inhibit the growth of tumor cells in animal models by inhibiting DNA synthesis and repair. 5'-O-tert-Butyldimethylsilyl-2,2'-anhydrouridine is also able to bind to RNA with high affinity, making it a potential candidate for use as an antiviral agent against HIV. This compound does not occur naturally in cells and can be synthesized from other nucleosides.</p>

<p>7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:</p>

<p>N4-Benzoyl-2-aza-3’-deazaadenine is a modified nucleoside that is synthesized from the natural deoxyribonucleoside adenine. It has been shown to have antiviral and anticancer properties. N4-Benzoyl-2-aza-3’-deazaadenine is a DNA Activator and can be used in the treatment of viral infections, such as HIV and herpes, as well as cancer. The drug binds to the viral DNA polymerase and prevents it from making new copies of the virus. This results in an accumulation of defective viruses within infected cells and ultimately cell death.</p>

<p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>

<p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside that contains a fluorinated sugar moiety and a thymine base, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl of the sugar.</p>