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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3567 productos de "Nucleósidos"

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  • 2'/3'-O-Trinitrophenyl-adenosine-5'-diphosphate triethylammonium salt

    CAS:
    <p>2'/3'-O-Trinitrophenyl-adenosine-5'-diphosphate triethylammonium salt (TPENAP) is an irreversible inhibitor of the enzyme adenosine kinase. TPENAP binds to the active site of the enzyme and blocks ATP synthesis, resulting in a rapid decrease in ATP levels. TPENAP is a potent fluorescence probe that reacts with tryptophan residues in proteins, thereby enhancing the fluorescence intensity. It has been shown to inhibit actin polymerization and depolymerize actin filaments, which may be due to its ability to inhibit ATP production.</p>
    Fórmula:C16H16N8O16P2
    Pureza:Min. 95%
    Peso molecular:638.29 g/mol

    Ref: 3D-NT29596

    3mg
    758,00€
    600µg
    328,00€
    1200µg
    463,00€
  • 5′-O-DMT-LNA N-dmf guanosine

    CAS:
    <p>5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.</p>
    Fórmula:C35H36N6O7
    Pureza:Min. 95%
    Peso molecular:652.7 g/mol

    Ref: 3D-ND182843

    1g
    547,00€
    250mg
    303,00€
    500mg
    410,00€
  • Ethyl-2,4-diamino-pyrimidine-5-carboxylate

    CAS:
    <p>Ethyl-2,4-diamino-pyrimidine-5-carboxylate is a nucleoside that is used in the synthesis of ribonucleosides and deoxyribonucleosides. It has been shown to be an activator for DNA polymerase and an antiviral agent. Ethyl-2,4-diamino-pyrimidine-5-carboxylate binds to the enzyme DNA polymerase and stimulates its activity by facilitating the conversion of RNA into DNA. This drug also inhibits the replication of virus cells by inhibiting viral RNA synthesis.</p>
    Fórmula:C7H10N4O2
    Pureza:Min. 95%
    Peso molecular:182.18 g/mol

    Ref: 3D-NE57380

    1g
    454,00€
    2g
    717,00€
    5g
    1.014,00€
    500mg
    300,00€
  • 5-Fluorouridine-5'-monophosphate sodium salt - 10mM aqueous solution

    CAS:
    <p>5-Fluorouridine-5'-monophosphate sodium salt is a nucleoside analog that is used as an antiviral drug. It inhibits viral DNA synthesis by competitive inhibition of thymidylate, which is a precursor for DNA synthesis. 5-Fluorouridine-5'-monophosphate sodium salt has been shown to be active against human pathogens and cancer cells in vitro. The enzyme activity of 5-fluorouridine-5'-monophosphate sodium salt can be inhibited by the presence of p-nitrophenyl phosphate, which is also a product of the enzymatic reaction. This may lead to synergistic effects in cells with both enzymes present.</p>
    Fórmula:C9H12FN2O9P
    Pureza:Min. 95%
    Forma y color:Colorless Powder
    Peso molecular:342.17 g/mol

    Ref: 3D-NF31487

    170µg
    410,00€
    340µg
    681,00€
  • S4-(2-Cyanoethyl)-5'-o-(dimethoxytrityl)-4-thiothymidine

    CAS:
    <p>S4-(2-Cyanoethyl)-5'-o-(dimethoxytrityl)-4-thiothymidine is a DNA analog that inhibits the growth of tumor cells. It binds to purine nucleosides and prevents the synthesis of DNA and RNA, which can lead to cell death. S4-(2-Cyanoethyl)-5'-o-(dimethoxytrityl)-4-thiothymidine has been shown to inhibit the growth of tumor cells in vitro. It is an effective inhibitor of HIV replication in vitro, but it does not have any antiviral activity against other viruses. This drug is a modified form of thymidine, which is an important component of DNA.</p>
    Fórmula:C34H35N3O6S
    Pureza:Min. 95%
    Peso molecular:613.7 g/mol

    Ref: 3D-SFA40974

    100mg
    894,00€
  • 3',5'-Bis-O-(t-butyldimethylsilyl)thymidine

    CAS:
    <p>3',5'-Bis-O-(t-butyldimethylsilyl)thymidine is a novel nucleoside phosphoramidite that can be used in the synthesis of oligonucleotides. This compound has antiviral and anticancer activities and is an excellent building block for the synthesis of modified nucleosides. 3',5'-Bis-O-(t-butyldimethylsilyl)thymidine is a high quality, high purity chemical with a CAS number of 40733-26-4.</p>
    Fórmula:C22H42N2O5Si2
    Pureza:Min. 95%
    Peso molecular:470.7 g/mol

    Ref: 3D-QBA73326

    50mg
    506,00€
    100mg
    767,00€
  • 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine

    CAS:
    <p>2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine is a nucleoside analog that inhibits DNA polymerase and RNA polymerase, which are enzymes vital for the production of DNA and RNA, respectively. This drug has been shown to be effective in treating cancer cells that are resistant to other chemotherapeutic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine has also been shown to inhibit viral replication by inhibiting viral reverse transcriptase.</p>
    Fórmula:C19H26FN3O8
    Pureza:Min. 95%
    Peso molecular:443.43 g/mol

    Ref: 3D-ND04660

    10mg
    303,00€
    25mg
    473,00€
    50mg
    701,00€
    100mg
    1.035,00€
  • 2'-Deoxyadenosine-5'-carboxylic acid

    CAS:
    <p>dA oxidised at the 5'-position.</p>
    Fórmula:C10H11N5O4
    Pureza:Min. 95%
    Peso molecular:265.23 g/mol

    Ref: 3D-ND158443

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  • N1-Methyladenosine hydroiodide

    CAS:
    <p>N1-Methyladenosine hydroiodide is a novel nucleoside analogue that inhibits viral replication by preventing the formation of viral DNA. It also inhibits the growth of cancer cells and is used as an anticancer drug. N1-Methyladenosine hydroiodide has been shown to be an activator of RNA polymerase II, increasing the production of messenger RNA (mRNA) in human cells. The phosphoramidite form of this compound is used for the synthesis of oligodeoxyribonucleotides, which are chemically modified in order to improve their stability and inhibit degradation by nucleases. N1-Methyladenosine hydroiodide is highly pure and has CAS No. 34308-25-3.</p>
    Fórmula:C11H15N5O4·HI
    Pureza:Min. 95%
    Peso molecular:409.18 g/mol

    Ref: 3D-NM08030

    50mg
    303,00€
    250mg
    416,00€
  • 3'-O-Allylcytidine


    <p>3'-O-Allylcytidine is a phosphoramidite nucleoside that is synthesized by the coupling of cytidine with allyl bromoacetate. It has antiviral activity, and has been shown to be active against herpes simplex virus type 1 (HSV-1) and hepatitis B virus (HBV). 3'-O-Allylcytidine has also been shown to inhibit the growth of cells in culture, suggesting that it may have anticancer properties. 3'-O-Allylcytidine is a novel monophosphate nucleoside that has not been previously reported.br&gt;</p>
    Fórmula:C12H17N3O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:283.28 g/mol

    Ref: 3D-NA05280

    10mg
    303,00€
    25mg
    353,00€
    50mg
    497,00€
    100mg
    769,00€
  • Biotin-5-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution


    <p>Biotin-5-deoxyuridine-5'-triphosphate, lithium salt is a novel phosphoramidite. It has been shown to be an anticancer agent and antiviral agent. Biotin-5-deoxyuridine-5'-triphosphate, lithium salt inhibits the growth of cancer cells by binding to the ribonucleotide reductase enzyme, thereby preventing synthesis of DNA and RNA.</p>
    Fórmula:C22H34N5O16P3S·xLi
    Pureza:Min. 95%
    Peso molecular:749.52 g/mol

    Ref: 3D-NB32060

    1g
    2.440,00€
  • 2',5'-Dideoxyinosine

    CAS:
    <p>2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.</p>
    Fórmula:C10H12N4O3
    Pureza:Min. 95%
    Peso molecular:236.23 g/mol

    Ref: 3D-ND08407

    10mg
    303,00€
    25mg
    414,00€
    50mg
    663,00€
    100mg
    1.065,00€
  • 5'-ODMT cEt N-Bzm5 C Phosphoramidite

    CAS:
    <p>Please enquire for more information about 5'-ODMT cEt N-Bzm5 C Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C49H56N5O9P
    Peso molecular:889.97 g/mol

    Ref: 3D-PO184479

    50mg
    607,00€
    100mg
    729,00€
  • 5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’- deoxyuridine

    CAS:
    <p>5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’-deoxyuridine is a monophosphate nucleoside analog that inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase. It is also antiviral, and has been shown to inhibit the growth of human erythroleukemia cells in vitro and to produce cytotoxic effects on murine leukemia cells. 5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’-deoxyuridine is an anticancer drug that has been shown to be effective against a variety of cancers, including those of the breast, lung, prostate, and colon. It has also been shown to have high quality as it does not cause any significant side effects or show cross resistance with other cancer drugs.</p>
    Fórmula:C14H16F3N3O6
    Pureza:Min. 95%
    Peso molecular:379.29 g/mol

    Ref: 3D-NT57550

    50mg
    303,00€
    100mg
    395,00€
    250mg
    702,00€
  • 5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite

    CAS:
    <p>5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a nucleoside analog and a potential anticancer drug. It is an excellent monophosphate, which can be used as a building block for synthesis of DNA. 5-Bromo-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite has antiviral activity against HIV and herpes simplex virus, as well as antifungal activity against Candida albicans. This compound has also been shown to have antitumor activity in vitro in the presence of other anticancer drugs.</p>
    Fórmula:C39H46BrN4O8P
    Pureza:Min. 95%
    Peso molecular:809.7 g/mol

    Ref: 3D-PB09116

    50mg
    303,00€
    100mg
    497,00€
    250mg
    738,00€
  • 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine

    CAS:
    <p>3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine is a novel nucleoside analogue that has been synthesized to inhibit the activity of DNA polymerase. This compound is also an activator of diphosphate and ribonucleoside monophosphate. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture and the replication of human cytomegalovirus in cell culture. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-- 2'-fluoroarabinocytidine does not have any antiviral activity against HIV.</p>
    Pureza:Min. 95%

    Ref: 3D-FD144469

    100mg
    303,00€
    250mg
    454,00€
  • O6-Benzyl guanosine

    CAS:
    <p>O6-Benzyl guanosine is a polymerized compound that has been shown to have anticancer efficacy. It has been tested in mice with medulloblastoma, a type of brain tumor, and in rats with breast cancer. O6-Benzyl guanosine was found to be hydrophobic and bound to the methyltransferase enzyme, which resulted in the inhibition of DNA synthesis. The polymerized compound is able to form conjugates with other molecules such as iron oxide nanoparticles or hydrazone derivatives, which can be used for treatments that involve bioconjugate chemistry.</p>
    Fórmula:C17H19N5O5
    Pureza:Min. 95%
    Peso molecular:373.36 g/mol

    Ref: 3D-NB16621

    10mg
    381,00€
    25mg
    523,00€
    50mg
    806,00€
  • 3',5'-Di-o-acetyl-O6-phenyl-2'-deoxyinosine

    CAS:
    <p>3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the enzyme ribonucleotide reductase and has been shown to be effective against herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, human immunodeficiency virus type 1, and Kaposi sarcoma cells. 3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine also inhibits the production of tumor necrosis factor alpha (TNFα), which can cause inflammatory reactions in the body. This compound is a modified nucleoside with high purity and quality. It has CAS number 133471-06-4.</p>
    Fórmula:C20H20N4O6
    Pureza:Min. 95%
    Peso molecular:412.4 g/mol

    Ref: 3D-IFA47106

    5g
    1.707,00€
  • 2,3'-Anhydrothymidine, methyl-D3

    Producto controlado

    <p>2,3'-Anhydrothymidine, methyl-D3 is a monophosphate nucleoside analogue that has antiviral and anticancer properties. It is a synthetic compound that has been modified to have some of the characteristics of natural DNA. 2,3'-Anhydrothymidine, methyl-D3 is an activator of ribonucleotide reductase and inhibits the synthesis of deoxyribonucleotides in cells. This compound can also be used as an anticancer agent due to its ability to inhibit DNA synthesis in cells.</p>
    Fórmula:C10H9D3N2O4
    Pureza:Min. 95%
    Peso molecular:227.23 g/mol

    Ref: 3D-NA06320

    1mg
    381,00€
    2mg
    589,00€
    5mg
    1.047,00€
    10mg
    1.447,00€
    25mg
    2.882,00€
  • 5-Chloro-2',3'-O-isopropylidenecytidine


    <p>5-Chloro-2',3'-O-isopropylidenecytidine is a synthetic nucleoside that is activated by phosphorylation to form the corresponding nucleotide. It has antiviral and anticancer properties, and can be used as a building block for synthesis of other nucleosides. 5-Chloro-2',3'-O-isopropylidenecytidine is synthesized from 2,4-dichlorophenoxyacetic acid (DCA) and 2,5-dichloroaniline in the presence of sodium cyanide. The compound was first synthesized in 1972 and its chemical structure was determined in 1974. 5-Chloro-2',3'-O-isopropylidenecytidine has been shown to inhibit DNA synthesis by binding to viral diphosphate and deoxyribonucleosides. This compound also inhibits the activity of bacterial DNA gyrase and DNA top</p>
    Fórmula:C12H16ClN3O5
    Pureza:Min. 95%
    Peso molecular:317.73 g/mol

    Ref: 3D-NC04761

    100mg
    303,00€
    250mg
    396,00€
  • 3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine


    <p>3'-O-Acetyl-2'-deoxy-2'-fluoro-5-methyluridine (3'-O-AFA) is a synthetic, novel antiviral agent that has been shown to inhibit the synthesis of DNA and RNA in cells infected with viruses. 3'-O-AFA is an activator that binds to ribonucleosides and deoxyribonucleosides, which are used in the synthesis of DNA and RNA respectively. The phosphoramidites are then converted into monophosphate or diphosphate nucleotides by the enzyme DNA polymerase. 3'-O-AFA is a modified nucleoside which can be incorporated into viral DNA during replication, inhibiting its production. This drug has also been shown to have anticancer properties against human tumor cells and may be effective against other cancers such as leukemia.</p>
    Fórmula:C12H15FN2O6
    Pureza:Min. 95%
    Peso molecular:302.26 g/mol

    Ref: 3D-NA08458

    1g
    838,00€
    100mg
    303,00€
    250mg
    354,00€
    500mg
    514,00€
  • 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite

    CAS:
    <p>5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a novel modified nucleoside analog. It is synthesized from the corresponding ribonucleoside and deoxyribonucleoside by means of a high-yield, convergent method. This compound has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV) in vitro. 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite also exhibits anticancer activities in cell culture.</p>
    Fórmula:C41H49N6O8P
    Pureza:Min. 95%
    Peso molecular:784.86 g/mol

    Ref: 3D-PD08575

    5g
    636,00€
    10g
    964,00€
    25g
    1.420,00€
  • 1,2'-O-Dimethylguanosine

    CAS:
    <p>1,2'-O-Dimethylguanosine is an activator of anticancer activity. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. 1,2'-O-Dimethylguanosine is a novel synthetic nucleoside analogue that can be modified to phosphoramidites and ribonucleosides for use as antiviral agents. This compound is also used as a building block for the synthesis of other nucleosides and nucleotides.</p>
    Fórmula:C12H17N5O5
    Pureza:Min. 95%
    Peso molecular:311.29 g/mol

    Ref: 3D-ND159481

    10mg
    2.745,00€
    25mg
    3.202,00€
    50mg
    4.575,00€
  • Octanoyl coenzyme A potassium salt

    CAS:
    <p>Octanoyl CoA is a molecule that belongs to the class of acyl-coenzyme A. It is an important intermediate in fatty acid metabolism and is also used in the synthesis of long-chain fatty acids. Octanoyl CoA can be converted back to acetyl-CoA by enzymes called synthetases, which are active in energy metabolism. Octanoyl CoA has been shown to have clinical relevance for diseases such as acyl chain disorders, carnitine deficiency, and dehydrogenase deficiency. Octanoyl CoA is a potential drug target since it can be converted into octanoic acid, which has been shown to inhibit enzyme activities and protein synthesis.</p>
    Fórmula:C29H47N7O17P3S·3K
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:1,008 g/mol

    Ref: 3D-NO47202

    2mg
    349,00€
    5mg
    486,00€
    10mg
    729,00€
    25mg
    1.491,00€
  • rac-Lamivudine acid

    CAS:
    <p>Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.</p>
    Fórmula:C8H9N3O4S
    Pureza:Min. 95%
    Peso molecular:243.24 g/mol

    Ref: 3D-NL27534

    5mg
    303,00€
    10mg
    430,00€
    25mg
    696,00€
    50mg
    1.129,00€
    100mg
    1.998,00€
  • 2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite

    CAS:
    <p>2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside analogue that inhibits the growth of cancer cells. It is used in the synthesis of oligonucleotides, which are used as drugs to treat cancers. This product has high purity and good quality and has been shown to be effective against cancer cells.</p>
    Fórmula:C39H46FN4O8P
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:748.8 g/mol

    Ref: 3D-PD08484

    1g
    921,00€
    2g
    1.410,00€
    100mg
    478,00€
    250mg
    547,00€
    500mg
    748,00€
  • 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole

    CAS:
    <p>1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole is an anticancer drug that has been shown to inhibit tumor growth in vivo. This drug binds to the integrin receptor, which is expressed on the surface of cells and is involved in the process of cell adhesion. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole inhibits tumor growth by inhibiting hypoxic tumor formation. Hypoxia is a condition where there is not enough oxygen for normal cell function. This drug has also been shown to reduce inflammation, which may be due to its ability to inhibit proinflammatory cytokines, such as IL-1β and TNFα, from binding to their receptors on cells. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-</p>
    Fórmula:C8H10FN3O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:247.18 g/mol

    Ref: 3D-ND07902

    2mg
    491,00€
    5mg
    831,00€
    10mg
    1.190,00€
    20mg
    2.074,00€
    50mg
    4.270,00€
  • a-Nicotinamide adenine dinucleotide phosphate

    CAS:
    <p>a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.</p>
    Fórmula:C21H28N7O17P3
    Pureza:Min. 95%
    Peso molecular:743.41 g/mol

    Ref: 3D-NN29116

    1g
    2.440,00€
  • 6-Methylcytidine

    CAS:
    <p>6-Methylcytidine is a nucleoside that is structurally related to uridine, which is an acceptor in DNA and RNA synthesis. It is synthesized from 8-bromoadenosine, which undergoes deamination by cytidine deaminase. 6-Methylcytidine can be used as a building block for the synthesis of other nucleosides with different conformational properties. It has been shown to inhibit the replication of pancreatic cancer cells and has been used in molecular modeling studies. However, its uptake into cells has been found to be very low. This may be due to its conformational properties and the presence of 8-oxoguanosine, which inhibits adenosine uptake into cells.</p>
    Fórmula:C10H15N3O5
    Pureza:Min. 95%
    Peso molecular:257.24 g/mol

    Ref: 3D-RAA71012

    10mg
    478,00€
    50mg
    706,00€
    100mg
    1.008,00€
  • 5'-ODMT cEt N-Bz A Phosphoramidite

    CAS:
    <p>Please enquire for more information about 5'-ODMT cEt N-Bz A Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C49H54N7O8P
    Peso molecular:899.97 g/mol

    Ref: 3D-PO184480

    25mg
    547,00€
    50mg
    729,00€
  • N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine

    CAS:
    <p>N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine is a synthetic nucleoside that has antiviral activity. It is activated by the enzyme ribonucleotide reductase and inhibits viral DNA synthesis. This agent also inhibits the production of deoxyribonucleosides, which are needed for DNA synthesis. In addition, this compound inhibits bacterial growth by inhibiting the enzyme DNA gyrase. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine has novel properties in that it does not contain any ribose or phosphate groups. This product is available as a white powder with a purity of at least 98%.</p>
    Fórmula:C38H34FN5O6
    Pureza:Min. 95%
    Peso molecular:675.71 g/mol

    Ref: 3D-NB08473

    1g
    1.131,00€
    5g
    4.260,00€
    100mg
    303,00€
    250mg
    493,00€
    500mg
    730,00€
  • 8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    <p>8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.</p>
    Fórmula:C10H17N6O13P3·xNa
    Pureza:Min. 95%
    Peso molecular:522.2 g/mol

    Ref: 3D-NA12011

    1mg
    353,00€
    2mg
    497,00€
    5mg
    872,00€
    10mg
    1.184,00€
    25mg
    1.973,00€
  • N,N-Dimethyl-2'-O-methylguanosine

    CAS:
    <p>N,N-Dimethyl-2'-O-methylguanosine is a nucleoside that belongs to the category of nucleosides. It is a chemical structure that has been shown to have research value for the study of nucleic acids and their related diseases. This compound is also used in posttranscriptional mechanisms and phylogenetic studies. N,N-Dimethyl-2'-O-methylguanosine can be synthesized from uridine, ribonucleotide, or other nucleosides through various chemical reactions. It is also used as a structural component in some pharmaceuticals.</p>
    Fórmula:C13H19N5O5
    Pureza:Min. 95%
    Peso molecular:325.32 g/mol

    Ref: 3D-ND159488

    100mg
    1.065,00€
  • Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide

    CAS:
    <p>Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is a novel cytidine phosphoramidate monophosphate that has been shown to have anticancer and antiviral properties. It can be used as a DNA nucleoside phosphoramidite in the synthesis of oligonucleotides or as an antiviral agent by inhibiting viral RNA replication. Cytidine 5’-phosphoromorpholidate N,N’-dicyclohexyl-4-morpholinecarboximidamide is chemically synthesized in high purity and quality for use in research in the field of DNA, nucleosides, and antiviral agents.</p>
    Fórmula:C30H52N7O9P
    Pureza:Min. 95%
    Peso molecular:685.75 g/mol

    Ref: 3D-NC165213

    2mg
    135,00€
    5mg
    136,00€
    10mg
    182,00€
    25mg
    291,00€
    50mg
    477,00€
  • 2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

    CAS:
    <p>2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside phosphoramidite that has antiviral and anticancer activity. This compound is a modified nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. 2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetylbD ribofuranosyl)purine binds to the catalytic site of the enzyme ribonucleotide reductase, which is essential for the production of dNTPs. This chemical also has shown anticancer activity in cell culture against leukemia cells and breast cancer cells, although it was not active against colon cancer cells.</p>
    Fórmula:C23H25N5O7S
    Pureza:Min. 95%
    Peso molecular:515.54 g/mol

    Ref: 3D-NA10196

    1g
    403,00€
    500mg
    300,00€
  • 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine

    CAS:
    <p>4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.</p>
    Fórmula:C29H56N4O4Si3
    Pureza:Min. 95%
    Peso molecular:609.04 g/mol

    Ref: 3D-NA04493

    5mg
    497,00€
    10mg
    768,00€
    25mg
    1.118,00€
  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG


    <p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG is a nucleotide analog with antiviral and anticancer activity. It is considered to be a novel nucleoside analogue. It is synthesized by attaching an acetyl group to the 2' position of the adenosine moiety, which prevents phosphorylation by kinase enzymes. This inhibits DNA synthesis and induces apoptosis in cancer cells.</p>
    Pureza:Min. 95%
    Forma y color:Powder

    Ref: 3D-ND57353

    25g
    303,00€
    50g
    355,00€
    100g
    562,00€
    250g
    1.128,00€
  • 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate

    CAS:
    <p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate is an analog of adenosine triphosphate (ATP). It inhibits the synthesis of RNA by binding to the ribonucleotide reductase enzyme. This inhibition leads to the inhibition of DNA synthesis, which in turn prevents cell division and/or causes cell death. The inhibitory effect of 2'-deoxy-2'-fluoroadenosine-5'-triphosphate on protein and DNA synthesis has been shown in vivo and in vitro using cell culture techniques. This compound inhibits topoisomerase II, a key enzyme in DNA replication, at high concentrations.</p>
    Fórmula:C10H15FNO12P3
    Pureza:Min. 95%
    Peso molecular:509.18 g/mol

    Ref: 3D-ND09532

    50mg
    2.104,00€
    100mg
    3.928,00€
  • Dibutyryladenosine cyclic 3',5'-monophosphate

    CAS:
    <p>Dibutyryladenosine cyclic 3',5'-monophosphate (DBACMP) is a mitochondrial function regulator that inhibits the synthesis of ATP by binding to the methyltransferase enzyme. DBACMP also has an inhibitory effect on other enzymes, such as dna binding activity and enzyme activities involved in cellular energy metabolism. DBACMP inhibits infectious diseases by altering signal pathways, which leads to the production of cytokines and chemokines that have pro-inflammatory effects and stimulate axonal growth. The drug may also bind to the atp-binding cassette transporter and inhibit mitochondrial calcium uptake. DBACMP binds to polymorphonuclear leucocytes and alters cytosolic calcium levels, which may lead to an increased production of protein genes for cell growth.</p>
    Fórmula:C18H24N5O8P
    Pureza:Min. 95%
    Peso molecular:469.39 g/mol

    Ref: 3D-NR145431

    1g
    1.536,00€
    2g
    2.930,00€
    500mg
    1.040,00€
  • 2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt - 100mM aqueous solution


    <p>2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt is an antiviral drug that inhibits viral DNA replication by inhibiting viral polymerase. It is a novel nucleoside analogue with antiviral activity against RNA viruses, including influenza virus and HIV. 2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt can be used as a precursor for the synthesis of modified monophosphate nucleosides, ribonucleosides and phosphoramidites. This product is supplied in high purity (98%) and high quality.</p>
    Fórmula:C9H14N2O14P3F·xLi
    Pureza:Min. 95%
    Peso molecular:486.13 g/mol

    Ref: 3D-ND46156

    1mg
    366,00€
    5mg
    778,00€
    10mg
    1.234,00€
    25mg
    2.275,00€
    2500µg
    449,00€
  • Pyrimidine-4-carboxylic acid hydrazide

    CAS:
    <p>Pyrimidine-4-carboxylic acid hydrazide (PCAH) is an antimycobacterial agent that inhibits the growth of Mycobacterium tuberculosis and other related species. PCAH is a ligand that binds to redox active metal ions, forming a supramolecular complex. The carboxyl group on PCAH reacts with the hydroxide ion in the presence of water to produce hydrogen peroxide, which in turn oxidizes the mycolic acids in the cell wall of M. tuberculosis, leading to cell death. The pyridine ring on PCAH is nucleophilic and can react with nucleophiles such as thiols or amines, which are found in proteins or peptides. This reaction results in nucleophilic substitutions, which inhibit bacterial protein synthesis and lead to cell death.</p>
    Fórmula:C5H6N4O
    Pureza:Min. 95%
    Peso molecular:138.13 g/mol

    Ref: 3D-NP57376

    1g
    454,00€
    2g
    693,00€
    5g
    1.014,00€
    500mg
    300,00€
  • Guanosine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution

    CAS:
    <p>Guanosine 5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analogue that binds to the guanine nucleotide-binding site on the enzyme. This agent has been shown to inhibit the growth of viruses, such as influenza virus and human immunodeficiency virus, by inhibiting viral transcription. The drug also has antiviral activity against herpesviruses and cytomegalovirus in cell culture. Guanosine 5'-O-(1-thiotriphosphate) lithium salt inhibits the binding of RNA polymerase to DNA templates and prevents the initiation of transcription. It also reduces the expression of a number of genes in cells by inhibiting protein synthesis in the cytoplasm. Guanosine 5'-O-(1-thiotriphosphate) lithium salt may be used for treating congestive heart failure due to its ability to reduce levels of cytosolic Ca2+ ions, which have been shown to promote cardiac my</p>
    Fórmula:C10H16N5O13P3S·4Li
    Pureza:Min. 95%
    Forma y color:Colourless liquid.
    Peso molecular:567.01 g/mol

    Ref: 3D-NG58207

    1mg
    303,00€
    2mg
    336,00€
    5mg
    491,00€
    10mg
    864,00€
    25mg
    1.672,00€
  • 4'-Ethynylthymidine

    CAS:
    <p>4'-Ethynylthymidine is a novel nucleoside analog that has been shown to be active against HIV-1. It has been shown to inhibit the incorporation of uridine into viral DNA and terminate elongation of viral DNA. 4'-Ethynylthymidine has also been shown to be active against other viruses such as vesicular stomatitis virus, influenza virus, and hepatitis C virus. The cytotoxicity of this drug is significant and may provide potential therapeutics for cancer treatment.</p>
    Pureza:Min. 95%

    Ref: 3D-NE170915

    1mg
    465,00€
    5mg
    1.570,00€
    10mg
    2.447,00€
  • Cytidine-5'-triphosphate, lithium salt


    <p>Cytidine-5'-triphosphate, lithium salt (CTP, Li) is a monophosphate that is used as a cofactor in the synthesis of DNA and RNA. It is also used for the treatment of viral infections. CTP, Li has antiviral activity against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), human cytomegalovirus (CMV) and Epstein-Barr virus (EBV). CTP, Li can be used to inhibit the growth of cancer cells by modifying DNA.</p>
    Pureza:Min. 95%

    Ref: 3D-NC32076

    1g
    2.440,00€
  • 2'-Deoxy-2'-methyleneadenosine

    CAS:
    <p>2'-Deoxy-2'-methyleneadenosine is a potential mechanism for the treatment of cancer. It has been shown to be active against the murine leukemia cell line, L1210, and to cause inactivation of the cells. This drug inhibits cellular RNA synthesis by binding to either the ribonucleoside or deoxyribonucleoside pools in the cell and preventing their conversion into nucleotides. 2'-Deoxy-2'-methyleneadenosine has also been shown to be an effective inhibitor of gamma-aminobutyric acid (GABA) uptake and cross-resistance with other drugs that are GABA uptake inhibitors.</p>
    Fórmula:C11H13N5O3
    Pureza:Min. 95%
    Peso molecular:263.25 g/mol

    Ref: 3D-ND157322

    1g
    2.536,00€
    2g
    4.260,00€
    500mg
    1.851,00€
  • N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine

    CAS:
    <p>N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane diyl) cytidine is a novel modified ribonucleoside. It is an activator of DNA and RNA synthesis with anticancer properties. N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane diyl) cytidine has been shown to be effective against influenza A virus and herpes simplex virus type 1. NACCTC has also shown antiviral activity against HIV type 2 in cell culture.</p>
    Fórmula:C23H41N3O7Si2
    Pureza:Min. 95%
    Peso molecular:527.76 g/mol

    Ref: 3D-NT57555

    1kg
    5.226,00€
    500g
    4.068,00€
  • N2-Methylguanosine-3',5'-cyclic monophosphate

    CAS:
    <p>N2-Methylguanosine-3',5'-cyclic monophosphate is a synthetic nucleoside that is the cyclic monophosphate analog of guanosine. It has antiviral, anticancer, and anti-inflammatory properties. N2-Methylguanosine-3',5'-cyclic monophosphate has been shown to inhibit viral replication in cells by inhibiting the synthesis of viral DNA and RNA. This compound also inhibits cancer cell growth in culture. The antiviral activity may be due to methylation at the 2' position of the sugar moiety, which prevents viral reverse transcriptase from copying viral RNA into DNA. The anticancer activity may be due to inhibition of ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes that maintain nucleotide pools necessary for DNA synthesis.</p>
    Fórmula:C11H13N5O7P·Na
    Pureza:Min. 95%
    Peso molecular:381.21 g/mol

    Ref: 3D-NM46114

    1mg
    328,00€
    5mg
    1.038,00€
    10mg
    1.661,00€
  • Uridine-15N2

    CAS:
    <p>Uridine-15N2 is a novel nucleoside that has antiviral, anticancer and antifungal effects. It has been shown to inhibit the growth of tumor cells by blocking the synthesis of DNA and RNA. Uridine-15N2 is synthesized from uridine-5N2 and 15N2 gas. This product is used in molecular biology research as a substrate for DNA polymerase, to study the enzymatic process of DNA replication. It can also be used as an activator for ribonuclesides or deoxyribonucleosides in organic synthesis. Uridine-15N2 is soluble in water and has a high purity.</p>
    Fórmula:C9H12N2O6
    Pureza:Min. 95%
    Peso molecular:244.20 g/mol

    Ref: 3D-SDA48768

    5mg
    817,00€
    10mg
    1.232,00€
    25mg
    1.957,00€
    50mg
    3.130,00€
  • Adenosine 5'-diphosphate potassium salt

    CAS:
    <p>Adenosine 5'-diphosphate potassium salt can be used as a substrate for a variety of protein kinases known as AMP-activated protein kinases (AMPK)</p>
    Fórmula:C10H14N5O10P2·K
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:465.29 g/mol

    Ref: 3D-NA10696

    5g
    347,00€
    10g
    589,00€
    25g
    1.190,00€
    50g
    2.196,00€
    100g
    3.660,00€
  • N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine


    <p>N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine is a modified nucleoside which can be used in the synthesis of DNA. It is phosphorylated to form N6-benzoyl-2'-deoxyadenosine monophosphate (BADAMP), which is converted to N6-benzoyl-2'-deoxyadenosine diphosphate (BADAP) through the action of ATP. The drug has antiviral properties and can be used to treat HIV infection.</p>
    Fórmula:C22H23N5O6
    Pureza:Min. 95%
    Peso molecular:453.46 g/mol

    Ref: 3D-NB06924

    2g
    303,00€
    5g
    456,00€
    10g
    798,00€