Nucleósidos

2'-Deoxyuridine-5'-diphosphate sodium salt is a novel antiviral agent that inhibits viral replication by inhibiting the activity of viral DNA polymerase. It is a synthetic nucleoside that is not found in nature, but is an analog of deoxyuridine monophosphate. This compound has been shown to be effective against tumor cells and has high purity with a CAS number 102814-06-2. 2'-Deoxyuridine-5'-diphosphate sodium salt is also used as an activator for phosphoramidites and modified nucleosides.

<p>5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å is a nucleoside analog that has been shown to be an effective anticancer agent. It has been shown to activate the cellular DNA synthesis by stimulating the phosphorylation of RNA polymerase II, which is involved in the transcription of DNA. 5'-O-DMT-thymidine-3'-succinyl CPG 1400 Å also inhibits viral replication and may be effective against AIDS. This nucleoside analog induces antiviral effects by inhibiting the synthesis of viral dsDNA.</p>

<p>4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-7-pteridone is a high purity, modified nucleoside that is synthesized from 2,4,6,8 tetramethylpyridine and 2'-deoxyribofuranosyl bromide. 4ADTP is an antiviral and anticancer agent that inhibits the viral DNA polymerase in the herpes family of viruses and the DNA polymerase in cancer cells. This drug has been shown to be active against HIV type 1 (HIV1) and HIV type 2 (HIV2).</p>

<p>2'-Amino-2'-deoxyuridine-5'-triphosphate (2dUDP) is a nucleotide that has been shown to be a potent inhibitor of cytosolic Ca2+ release. 2dUDP binds to the Ryanodine receptor (RYR) and inhibits the release of Ca2+ from the sarcoplasmic reticulum. It is also fluorescent, and can be used to detect Ca2+ in cells. This nucleotide has been shown to inhibit populations of heterologous and homologous RYR receptors.</p>

4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.

<p>Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.</p>

<p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It is a modified nucleoside with a purine base. It has been shown to be effective against certain cancer cells in vitro and in vivo. This drug also has antiviral properties, which may be due to its ability to inhibit DNA synthesis through the inhibition of viral RNA replication. 2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is resistant to phosphorylation by kinase enzymes and it can be used as a precursor for the preparation of other nucleosides.</p>

<p>2'-Ethylfluoro-5-methyluridine is a nucleoside analog. It has been modified with an ethyl group at the 2' position of the sugar moiety and a fluoro atom in the 5-position of the uracil base that replaces the methyl group. This modification increases its cellular uptake and antiviral activity. It is being studied as a potential anticancer drug.</p>

<p>7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has a</p>

Please enquire for more information about Aracytidylyl-(5′→5′)-cytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>3'-Azido-N4-benzoyl-2',3'-dideoxy5'-O-DMT-cytidine is a novel nucleoside analog that has antiviral activity against herpes simplex virus type 1. It is a modified nucleoside phosphoramidite with an azido group at the 3' position and a benzoyl group at the 2' position of cytidine. This product can be used for the synthesis of oligonucleotides with high purity and high quality. This product has CAS number 271462-87-6.</p>

N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has the potential to be a therapeutic agent for cancer and antiviral therapy. It is an analog of adenosine that inhibits viral replication by inhibiting the viral enzyme RNA-dependent DNA polymerase. N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine also inhibits tumor growth by inducing apoptosis. The compound has been shown to inhibit human leukemia cells in vitro, as well as mouse leukemia cells in vivo. This novel nucleoside is synthesized through a two step process starting with 5'-chloroadenosine and converting it to 5'-chloroinosidine with potassium cyanide, followed by deoxygenation at the 6 position with benzoyl chloride and sodium hydroxide.

2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an antiviral nucleoside. It is a novel nucleotide analog that inhibits human immunodeficiency virus (HIV). The cytidine monophosphate moiety of 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine has been modified with the substitution of the acetyl group at the 2' position with a deoxyribose group, and the 5' fluoro group with a 5'-deoxyfluro group. This modification prevents phosphodiesterases from hydrolyzing it to its monophosphate form, which leads to higher antiviral activity. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro -

N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.

<p>6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is a novel nucleoside analog that has been modified to contain an antiviral agent. It is phosphorylated at the 2' position to form a monophosphate. This compound is a potent inhibitor of HIV reverse transcriptase and human DNA polymerases α and β. The structure of this compound contains a furano ring fused with the pyrimidine moiety, which is substituted with methyl groups on C6 and C3 positions. The CAS number for 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is 383897−60−7.</p>

<p>5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å is an Activator that is a monophosphate and synthesized through the modification of nucleosides. It has novel anticancer properties and is a high quality, high purity, and modified nucleotide. The 5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å has been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) in human cells. It also has anticancer effects on human leukemia cells by inhibiting the growth of cancer cells.</p>

a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.

N4-Acetyl-2'-deoxy-2'-fluoro-2'C-methylcytidine is a novel nucleoside analogue that is currently being studied as an anti-cancer agent. It inhibits the growth of cancer cells by inhibiting the synthesis of DNA, RNA and proteins in these cells. N4-Acetyl-2'-deoxy-2'-fluoro-2'C-methylcytidine has been shown to be active against Hepatitis C virus and HIV, but not against influenza virus. This drug also has antiviral activity and can be used for the treatment of herpes simplex viruses type 1 and 2.

<p>Biotinyl coenzyme A is a novel, synthetic nucleotide that has activity against cancer cells. It is an analogue of biotin-diphosphate with a ribonucleoside moiety attached to the diphosphate. Biotinyl coenzyme A is phosphoramidite monophosphate, which can be synthesized by modifying the 5'-terminus of the anticancer drug gemcitabine.</p>