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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3569 productos de "Nucleósidos"

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  • 3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine


    <p>3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.</p>
    Pureza:Min. 95%

    Ref: 3D-NA145616

    100mg
    303,00€
    250mg
    580,00€
    500mg
    1.003,00€
  • 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine


    <p>3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine is a novel, modified nucleoside. This product is an activator of the ribonucleotide reductase enzyme and is used as a precursor in the synthesis of deoxyribonucleosides. It has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It has also been shown to have anticancer properties, as it inhibits DNA synthesis and tumor cell proliferation without affecting healthy cells. 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT uridine is synthesized from 5-(3,4,5)-trimethoxybenzaldehyde, 2′(2,6 dichloro)amino]methyl]benzeneacetic acid methyl ester and 5</p>
    Pureza:Min. 95%

    Ref: 3D-NA144580

    3g
    4.574,00€
  • 1-(b-D-Arabinofuranosyl)-5-iodouracil

    CAS:
    <p>1-(b-D-Arabinofuranosyl)-5-iodouracil is a synthetic nucleoside that has antiviral and anticancer properties. It is a monophosphate nucleotide that inhibits viral RNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This inhibitor also blocks DNA synthesis by preventing the incorporation of b-D-arabinofuranosyl monophosphate into DNA. 1-(b-D-Arabinofuranosyl)-5-iodouracil has been shown to be effective in treating various types of cancer, including breast, lung, and prostate cancers. It also exhibits antitumor activity against certain human leukemia cells.</p>
    Fórmula:C9H11IN2O6
    Pureza:Min. 95%
    Peso molecular:370.1 g/mol

    Ref: 3D-NA09572

    1g
    2.440,00€
  • 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine

    CAS:
    <p>3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.</p>
    Fórmula:C13H14BrFN2O7
    Pureza:Min. 95%
    Peso molecular:409.16 g/mol

    Ref: 3D-ND15626

    100mg
    303,00€
    250mg
    454,00€
  • 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde

    CAS:
    <p>2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS.<br>2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of</p>
    Fórmula:C12H11N3OS
    Pureza:Min. 95%
    Peso molecular:245.3 g/mol

    Ref: 3D-NM57378

    1g
    478,00€
    2g
    725,00€
    5g
    1.067,00€
    500mg
    300,00€
  • 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine

    CAS:
    5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs such
    Fórmula:C37H37F3N4O9
    Pureza:Min. 95%
    Peso molecular:738.74 g/mol

    Ref: 3D-ND08236

    1g
    1.120,00€
    100mg
    303,00€
    250mg
    413,00€
    500mg
    669,00€
  • 2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one

    CAS:
    <p>2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.</p>
    Fórmula:C10H13N5O4
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:267.24 g/mol

    Ref: 3D-NA145593

    1g
    5.164,00€
    50mg
    463,00€
    100mg
    724,00€
    250mg
    1.550,00€
    500mg
    2.821,00€
  • 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine

    CAS:
    1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).
    Fórmula:C9H12ClN3O4
    Pureza:Min. 95%
    Peso molecular:261.66 g/mol

    Ref: 3D-NC29834

    5g
    A consultar
  • 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.
    Fórmula:C11H17N4O13P3·xLi
    Pureza:Min. 95%
    Peso molecular:506.19 g/mol

    Ref: 3D-ND157323

    1mg
    349,00€
    2mg
    574,00€
    5mg
    906,00€
    10mg
    1.600,00€
    500µg
    300,00€
  • 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine


    5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.
    Fórmula:C12H15ClIN3O4
    Pureza:Min. 95%
    Peso molecular:427.63 g/mol

    Ref: 3D-NC04650

    100mg
    303,00€
    250mg
    497,00€
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.</p>
    Fórmula:C47H64N7O7Si
    Pureza:Min. 95%
    Peso molecular:867.14 g/mol

    Ref: 3D-NB139123

    1g
    2.380,00€
    2g
    4.136,00€
    250mg
    1.190,00€
    500mg
    1.883,00€
  • 4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone


    <p>4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.</p>
    Fórmula:C29H29N5O6
    Pureza:Min. 95%
    Peso molecular:543.57 g/mol

    Ref: 3D-NA07206

    1mg
    315,00€
    2mg
    483,00€
    5mg
    793,00€
    10mg
    1.387,00€
    500µg
    300,00€
  • 2'-Deoxy-5-hydroxyuridine 5'-triphosphate

    CAS:
    <p>2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.</p>
    Pureza:Min. 95%

    Ref: 3D-ND168484

    10mg
    4.269,00€
  • 6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine

    CAS:
    <p>6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety can</p>
    Fórmula:C24H18CIFN4O5
    Pureza:Min. 95%
    Peso molecular:496.89 g/mol

    Ref: 3D-NC08475

    25mg
    303,00€
    50mg
    314,00€
    100mg
    471,00€
  • Guanosine 5'-triphosphate trisodium hydrate

    CAS:
    <p>Guanosine 5'-triphosphate trisodium hydrate is a novel antiviral agent that was discovered in the course of a research program to find new antiviral agents. It is an activator of guanylyl cyclase and it has been shown to have high quality and high purity. Guanosine 5'-triphosphate trisodium hydrate binds to ribonucleosides and deoxyribonucleosides, preventing their incorporation into viral DNA or RNA. This compound also has anticancer activity.</p>
    Fórmula:C10H18N5NaO15P3
    Pureza:Min. 95%
    Peso molecular:564.19 g/mol

    Ref: 3D-HIA30085

    1g
    962,00€
  • 3'-Azido-3'-deoxy-5-methylcytidine

    CAS:
    <p>3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.</p>
    Pureza:Min. 95%

    Ref: 3D-NA163051

    5mg
    303,00€
    10mg
    357,00€
    25mg
    596,00€
  • N6-Benzoyl-3'-deoxyadenosine

    CAS:
    N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.
    Fórmula:C17H17N5O4
    Pureza:Min. 95%
    Peso molecular:355.35 g/mol

    Ref: 3D-NB31303

    50mg
    303,00€
    100mg
    364,00€
    250mg
    702,00€
    500mg
    1.152,00€
  • 2',3'-Anhydroinosine

    CAS:
    2',3'-Anhydroinosine is an analog of the purine nucleoside inosine, which has been synthesized by catalytic dehalogenation of 2-fluoro-adenosine. The synthesis of this compound is based on a chemical reaction between 2-fluoro-adenosine and sodium hydroxide. This reaction produces 2',3'-anhydroinosine as a byproduct. 2',3'-Anhydroinosine inhibits the enzyme purine nucleoside phosphorylase, which prevents the conversion of inosine to hypoxanthine. This prevents purines from being used for protein synthesis, leading to cell death.
    Fórmula:C10H10N4O4
    Pureza:Min. 95%
    Peso molecular:250.21 g/mol

    Ref: 3D-NA17929

    250mg
    2.198,00€
  • Uridylyl-2'-5'-uridine ammonium salt

    CAS:
    Uridylyl-2'-5'-uridine ammonium salt is a monophosphate nucleoside that is a synthetic compound of uridine. It is an antiviral agent and has been shown to be effective against DNA viruses such as herpes simplex virus and Epstein-Barr virus. Uridylyl-2'-5'-uridine ammonium salt binds to the viral DNA, preventing the replication process from occurring. This drug also has anticancer properties, which are attributed to its ability to inhibit DNA synthesis in cells.
    Fórmula:C18H23N4O14P·NH3
    Pureza:Min. 95%
    Peso molecular:567.41 g/mol

    Ref: 3D-NU07988

    2mg
    303,00€
    5mg
    497,00€
  • b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate

    CAS:
    b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate is a novel anticancer compound that has been shown to inhibit the growth of cancer cells in vitro. The mechanism of action of b-NADP+ is still unknown, but it may involve the inhibition of ribonucleoside reductase and deoxyribonucleoside reductase. It also inhibits viral DNA synthesis, which can be an effective antiviral drug. b-NADP+ is a nucleotide analogue that is synthesized from diphosphate and monophosphate forms, which are activated by phosphoramidites.
    Fórmula:C21H28N7O17P3•K•(H2O)2
    Pureza:Min. 95%
    Peso molecular:818.5 g/mol

    Ref: 3D-NN11481

    100g
    3.379,00€