Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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3'-O-Methyl-5-methylcytidine
CAS:3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.Fórmula:C11H17N3O5Pureza:Min. 95%Forma y color:PowderPeso molecular:271.27 g/mol2'-Deoxyadenosine-5'-monophosphate disodium salt
CAS:2'-Deoxyadenosine-5'-monophosphate disodium salt (DAP) is a white crystalline powder. It is soluble in water and insoluble in ethanol. DAP can be neutralised by aqueous solutions of hydroxide, such as sodium hydroxide or ammonium hydroxide. DAP is also reactive with aluminium oxide, which can be used for drying the compound to form anhydrous particles. DAP reacts with chloride ions to form 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride, which has been shown to inhibit bacterial growth and act as an antibacterial agent. Autoclaving may be required for preparation of this drug due to its sensitivity to heat energy.Fórmula:C10H12N5Na2O6PPureza:Min. 99 Area-%Forma y color:White PowderPeso molecular:375.19 g/molCyclopentenyl cytosine
CAS:Cyclopentenyl cytosine is a cytotoxic drug that inhibits the synthesis of DNA, RNA, and proteins. It is a nucleoside analogue that inhibits the enzyme activity of ribonucleotide reductase. Cyclopentenyl cytosine has significant cytotoxicity against hl-60 cells, as well as squamous carcinoma and MDA-MB-231 breast cancer cells. It also has significant activity against cyclopentenyl, dextran sulfate, and mitochondrial functions in vivo in human cells. Cyclopentenyl cytosine binds to the response element on the DNA strand, preventing transcription of genes for protein synthesis and cell division.
Fórmula:C10H13N3O4Pureza:Min. 95%Forma y color:PowderPeso molecular:239.23 g/molAdenosine 5'-phosphosulfate sodium salt, 10 mM in water
CAS:Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP).Product provided as 10 mM solution in water.Fórmula:C10H14N5O10PSPureza:Min. 90.0 Area-%Peso molecular:427.28 g/mol2-Chloro-N6-cyclopentyladenosine hemihydrate
CAS:2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applicationsFórmula:C15H20ClN5O4H2OPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:378.81 g/mol4’,5’-Didehydro-2’-O-(2-methoxyethyl)uridine
CAS:4’,5’-Didehydro-2’-O-(2-methoxyethyl)uridine (4,5DDMU) is a novel nucleoside analog that is phosphorylated to 4,5-didehydro-2'-O-(2-methoxyethyl)uridine 5'-triphosphate. This nucleoside has been shown to inhibit the proliferation of human cancer cells in vitro and in vivo. 4,5DDMU inhibits viral replication by generating diphosphate derivatives of the viral DNA polymerase enzyme that are unable to synthesize DNA. 4,5DDMU also inhibits HIV replication by inhibiting reverse transcriptase activity in the virus.End>Pureza:Min. 95%N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite
N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite is a novel nucleoside analog that has shown anticancer and antiviral activity. It is a monophosphate, modified nucleoside that inhibits the deoxyribonucleotide biosynthetic pathway in cells. N4-Benzoyl-3'-O-tert-butydimethylsilylcytidine 2'-CE-phosphoramidite can be used as an activator of ribonuclease S1 and ribonuclease T1, which are enzymes involved in the process of DNA replication. In addition to its use as a therapeutic agent, this compound is also used for research purposes.Fórmula:C52H66N5O9PSiPureza:Min. 95%Peso molecular:964.17 g/molAdenylyl-3'-5'-adenosine ammonium salt
CAS:Adenylyl-3'-5'-adenosine ammonium salt is a novel and activator. CAS No. 21027-46-3. Ribonuclesides, Deoxyribonucleosides, diphosphate, Phosphoramidites, Modified, Anticancer, Antiviral, monophosphate, Nucleosides, Synthetic. High quality and high purity.
Fórmula:C20H25N10O10PPureza:Min. 95%Peso molecular:596.45 g/mol5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite
CAS:5-Aza-N6-benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a monophosphate, Synthetic, DNA Activator, Anticancer, Modified, Novel, Nucleosides. It has the CAS No. 929904-98-3 and is High purity.Fórmula:C46H53N6O9PPureza:Min. 95%Peso molecular:864.92 g/mol7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS:7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides. It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.Pureza:Min. 95%1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine
CAS:1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine is a cytosine analog that is structurally similar to the antiviral drug tenofovir. It has been shown to be active against human serum and logarithmic growth phase cells, as well as cancer cell lines. 1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine inhibits HIV infection in vitro by binding to the viral reverse transcriptase enzyme, blocking its activity and preventing DNA synthesis. This drug also inhibits the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in cell culture.Fórmula:C9H12FN3O3Pureza:Min. 95%Peso molecular:229.21 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol
CAS:1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in researchFórmula:C24H22N2O7Pureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:450.45 g/molN4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFórmula:C38H52N5O8PSiPureza:Min. 95%Peso molecular:765.93 g/molN-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite
CAS:N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite is a nucleoside and nucleotide analog. It is synthesized by reacting 2'-deoxyguanosine with acetyl chloride, 5'-dimethoxytrityl chloride, and 3'-Ce phosphoramidite in an organic solvent. N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine has been shown to inhibit the growth of cancer cells and viruses in cell culture studies. It is also a potent inhibitor of HIV replication in vitro.Fórmula:C49H66N7O9PSiPureza:Min. 95%Forma y color:PowderPeso molecular:956.15 g/molAdenosine 5'-monophosphate disodium salt
CAS:Adenosine 5'-monophosphate disodium salt (AMP-Na2) is a chemical compound that has been used in the study of metabolic disorders. It belongs to the class of ethylene diamines and has been shown to increase the glomerular filtration rate. Ammonium adenosine 5'-monophosphate disodium salt has also been shown to increase the activity of glutamate decarboxylase, which converts glutamate into GABA, an inhibitory neurotransmitter. The neutral pH optimum for AMP-Na2 is 6.5-7.5, which may be due to its lysine residues. AMP-Na2 has a carbonyl group that can be oxidized by reactive oxygen species and cause oxidative injury to cells in vivo and in vitro. This damage was found mainly in microglia cells, which are responsible for removing dead or damaged neurons from the central nervous system (CNS). AMP-Na2 also activates adFórmula:C10H12N5Na2O7PPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:391.19 g/mol2',5'-Dideoxyadenosine
CAS:2',5'-Dideoxyadenosine is a nucleotide analog that inhibits the enzyme adenylate cyclase, by binding non-competitively via the P-site
Fórmula:C10H13N5O2Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:235.25 g/mol9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine
CAS:9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is a modified nucleoside with anticancer activity. It has been shown to be an effective activator of DNA, RNA, and protein synthesis in vitro. This drug has also been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and influenza A virus. 9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is an analog of the natural purine metabolite hypoxanthine that can be synthesized in high purity.Pureza:Min. 95%5'-O-DMT-N2-DMF-guanosine
CAS:5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.Fórmula:C34H36N6O7Pureza:(%) Min. 85%Peso molecular:640.69 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS:5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.
Fórmula:C31H31N5O6Pureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:569.61 g/molBBQ-650-DT CEP
CAS:BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.Fórmula:C76H89N12O15PPureza:Min. 95%Peso molecular:1,441.6 g/mol
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