Antraciclinas
Las antraciclinas son una clase de potentes antibióticos antitumorales ampliamente utilizados en la quimioterapia del cáncer. Estos compuestos actúan intercalándose en el ADN, lo que interfiere con la función de la topoisomerasa II e impide la replicación de las células cancerosas. Las antraciclinas son particularmente efectivas contra una amplia gama de cánceres, incluyendo leucemias, linfomas y cáncer de mama. Sin embargo, su uso a menudo está limitado por su cardiotoxicidad, lo que hace que la investigación en formulaciones más seguras y efectivas sea un área clave de enfoque. En CymitQuimica, ofrecemos una selección de antraciclinas para su investigación en oncología, desarrollo de fármacos y terapia contra el cáncer.
Se han encontrado 173 productos de "Antraciclinas"
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7,8,9,10-Dehydro Doxorubicinone (~70%)
CAS:Producto controladoFórmula:C21H14O8Pureza:~70%Forma y color:NeatPeso molecular:394.33Doxorubicin Imp B HBr salt
CAS:<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>Fórmula:C29H34BrNO11BrHPureza:Min. 95%Peso molecular:733.4 g/molDoxorubicin Impurity 15
CAS:<p>Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.</p>Fórmula:C31H38BrNO11Pureza:Min. 95%Peso molecular:680.54 g/molDes[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone
CAS:<p>Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.</p>Fórmula:C18H19N3O5Pureza:Min. 95%Peso molecular:357.36 g/molEpirubicin
CAS:<p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>Fórmula:C27H29NO11Forma y color:SolidPeso molecular:543.52Mitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:<p>Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.</p>Fórmula:C22H26N4O6Pureza:Min. 95%Forma y color:Brown PowderPeso molecular:442.47 g/molDoxorubicin Dimer Impurity-1
<p>Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>Fórmula:C54H56N2O21Pureza:Min. 95%Peso molecular:1,069.02 g/molRef: 4Z-D-3456
Producto descatalogadoRef: 4Z-D-3478
Producto descatalogadoRef: 4Z-D-3468
Producto descatalogadoRef: 4Z-D-3479
Producto descatalogadoRef: 4Z-D-3477
Producto descatalogadoRef: 4Z-D-3490
Producto descatalogadoRef: 4Z-D-3415
Producto descatalogadoRef: 4Z-M-088012
Producto descatalogadoRef: 4Z-D-3476
Producto descatalogadoRef: 4Z-D-3480
Producto descatalogadoRef: 4Z-D-3455
Producto descatalogadoRef: 4Z-D-3457
Producto descatalogadoRef: 4Z-D-3424
Producto descatalogado
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