Proteína de transporte de membrana
Se han encontrado 68 productos de "Proteína de transporte de membrana"
Reboxetine mesylate - Bio-X ™
CAS:Producto controladoReboxetine mesylate is a drug that belongs to the class of tricyclic antidepressants. It is a selective and potent inhibitor of neuronal reuptake of norepinephrine (noradrenaline). Reboxetine also interacts with neurokinin-1 receptors, which may affect locomotor activity and hippocampal formation, resulting in effects to memory and learning. It has been shown to be effective in the treatment of symptoms related to depression and Parkinson's disease.Fórmula:C20H27NO6SPureza:Min. 98 Area-%Peso molecular:409.5 g/molMaprotiline HCl - Bio-X ™
CAS:Producto controladoMaprotiline is a tetracyclic antidepressant that is used for the treatment of major depressive disorder and anxiety that is associated with depression. This drug inhibits noradrenaline reuptake and has anticholinergic properties. Additionally, Maprotiline inhibits the amine transporter which allows for a delay in the reuptake of noradrenaline.
Fórmula:C20H23N•HClPureza:Min. 95%Forma y color:PowderPeso molecular:313.86 g/molPF 03463275
CAS:Orally available and central nervous system-penetrant inhibitor of GlyT1 glycine transporter SLC6A9. PF 03463275 was shown to enhance neuroplasticity and cognitive remediation in schizophrenia patients. In animal studies, PF 03463275 also influenced retina as changes in electroretinogram were detected in albino rats.Fórmula:C19H22ClFN4OPureza:Min. 95%Peso molecular:376.86 g/molDalcetrapib
CAS:Inhibitor of CETP exchange protein
Fórmula:C23H35NO2SPureza:Min. 98 Area-%Peso molecular:389.6 g/molUK 5099
CAS:Specific inhibitor of the mitochondrial pyruvate carrier complexes MPC1 and MPC2. The compound blocks the pyruvate transport across the inner mitochondrial membrane and therefore reduces pyruvate influx into the gluconeogenesis. It supresses glucose production in hepatocytes and was proposed for the control of hyperglycaemia in diabetic patients. Also used for the sensitisation of cancer cell lines to chemotherapy.Fórmula:C18H12N2O2Pureza:Min. 95%Forma y color:Off-White Yellow PowderPeso molecular:288.3 g/molDapagliflozin - Bio-X ™
CAS:Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. It inhibits glucose reabsorption in the proximal tubule of the nephron and results in glycosuria, which helps to improve glycaemic control. Also, Dapagliflozin is used to lower the risk of sustained eGFR decline, end-stage renal disease, cardiovascular death, and hospitalization for heart failure in patients with chronic kidney disease who are at risk of progression.Fórmula:C21H25ClO6Pureza:Min. 99 Area-%Forma y color:PowderPeso molecular:408.87 g/molDihydrokainic acid
CAS:Non-transportable inhibitor of GLT-1 glutamate transporterFórmula:C10H17NO4Pureza:Min. 95%Peso molecular:215.25 g/molNortriptyline
CAS:Producto controladoSerotonin and norepinephrine reuptake inhibitor; anti-depressantFórmula:C19H21NPureza:Min. 95%Forma y color:PowderPeso molecular:263.38 g/molValspodar
CAS:P-glycoprotein (MDR1) inhibitor; non-immunosuppressive cyclosporin A analog
Fórmula:C63H111N11O12Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:1,214.62 g/molLofepramine - Bio-X ™
CAS:Lofepramine is a psychoactive drug that belongs to the class of tricyclic antidepressants. It is used to treat depression and anxiety disorders. This drug works by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine and as a result these neurotransmitters remain active in the brain for a longer period, which can help improve mood and alleviate symptoms of depression.
Fórmula:C26H27ClN2OPureza:Min. 95%Forma y color:PowderPeso molecular:418.96 g/molBrefeldin A
CAS:Inhibits protein translocation from ER to Golgi; fungal metabolite
Fórmula:C16H24O4Pureza:Min. 95%Forma y color:PowderPeso molecular:280.36 g/molIpragliflozin
CAS:Inhibitor of sodium-glucose cotransporter SGLT2
Fórmula:C21H21FO5SPureza:Min. 95%Forma y color:PowderPeso molecular:404.45 g/molBupropion HCl - Bio-X ™
CAS:Producto controladoBupropion is an antidepressant drug that has been used in treatment trials for major depressive disorder. It has been shown to be effective in combination therapy with other drugs, such as a serotonin reuptake inhibitor (SSRI) or a tricyclic antidepressant (TCA). The drug's mechanism of action is not well understood but is said to increase the levels of dopamine and norepinephrine by inhibiting their reuptake.Fórmula:C13H18ClNO•HClPureza:Min. 95%Forma y color:PowderPeso molecular:276.2 g/molDL-Dapoxetine HCl - Bio-X ™
CAS:Producto controladoDapoxetine is a serotonin reuptake inhibitor drug that is used to treat premature ejaculation. This drug works by increasing the levels of serotonin in the brain, which in turn can help to delay the reflex that triggers ejaculation. As a result, it delays ejaculation and improves control over this.Fórmula:C21H23NO•HClPureza:Min. 95%Forma y color:PowderPeso molecular:341.87 g/molImipramine HCl - Bio-X ™
CAS:Producto controladoImipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.Fórmula:C19H24N2•HClPureza:Min. 95%Forma y color:PowderPeso molecular:316.87 g/molBI 01383298
CAS:Potent inhibitor of the sodium-coupled citrate cotransporter SLC13A5 (NaCT, INDY). The compound is not structurally related to citrate and is selective for SLC13A over other related transporters.
Fórmula:C19H19Cl2FN2O3SPureza:Min. 95%Forma y color:SolidPeso molecular:445.34 g/molAnacetrapib
CAS:A potent inhibitor of CETP that inhibits transfer of cholesteryl esters and triglycerides. Raises HDL cholesterol levels whilst lowering LDL cholesterol. Reduces cardiovascular events in patients with atherosclerotic vascular disease that receive statin treatment.
Fórmula:C30H25F10NO3Pureza:Min. 95%Forma y color:PowderPeso molecular:637.51 g/molRef: 3D-FA17899
Producto descatalogadoAZD 3965
CAS:AZD3965 is a potent, selective and orally available monocarboxylate transporter 1 (MCT1) inhibitor with binding affinity of 1.6 nM, 6-fold selective for MTC1 over MCT2.
Fórmula:C21H24F3N5O5SPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:515.51 g/molRef: 3D-BA164976
Producto descatalogadoClomipramine hydrochloride - Bio-X ™
CAS:Producto controladoClomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.
Fórmula:C19H24Cl2N2Pureza:Min. 95%Forma y color:White PowderPeso molecular:351.31 g/molZosuquidar trihydrochloride
CAS:Inhibits P-gp transporters ; modulates P-gp-mediated multidrug resistance
Fórmula:C32H34Cl3F2N3O2Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:636.99 g/mol
