Inhibidores
Los inhibidores son moléculas que se unen a enzimas, receptores u otras proteínas para reducir o bloquear su actividad biológica. Estos compuestos se utilizan ampliamente en la investigación para estudiar vías biológicas, comprender los mecanismos de las enfermedades y desarrollar fármacos terapéuticos. Los inhibidores desempeñan un papel crucial en el tratamiento de diversas enfermedades, incluyendo el cáncer, las enfermedades cardiovasculares y las infecciones. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo farmacéutico.
Subcategorías de "Inhibidores"
- Angiogénesis(2.519 productos)
- Apoptosis(5.786 productos)
- Ciclo celular / Checkpoint(4.444 productos)
- Cromatina / Epigenética(2.235 productos)
- Señalización citoesquelética(1.382 productos)
- Daño al ADN / Reparación del ADN(2.823 productos)
- Endocrinología / Hormonas(3.499 productos)
- Enzima(3.639 productos)
- GPCR / proteína G(8.314 productos)
- Inmunología e inflamación(3.516 productos)
- Virus de la gripe(296 productos)
- Señalización JAK / STAT(404 productos)
- Señalización MAPK(1.199 productos)
- Transportador de membrana / canal de iones(2.786 productos)
- Metabolismo(9.417 productos)
- Microbiología / Virología(6.967 productos)
- Neurociencia(9.920 productos)
- Otros inhibidores(37.931 productos)
- Reducción de oxidación(41 productos)
- Señalización PI3K / Akt / mTOR(1.399 productos)
- Proteasas / Proteasoma(1.596 productos)
- Células madre y Derivados(832 productos)
- Tirosina quinasa / adaptadores(2.015 productos)
- Ubiquitinación(1.646 productos)
Mostrar 16 subcategorías más
Se han encontrado 66627 productos de "Inhibidores"
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Androgen receptor antagonist 5
CAS:<p>AR antagonist 5 blocks AR (IC50: 6.17 μM), hinders LNCaP cell growth, and has anti-tumor effects in mouse models.</p>Fórmula:C21H15F4N5O3SForma y color:SolidPeso molecular:493.43FGFR-IN-2
CAS:<p>FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).</p>Fórmula:C25H30N6O2Forma y color:SolidPeso molecular:446.54WEHI-345
CAS:<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Fórmula:C22H23N7OPureza:>99.99%Forma y color:SolidPeso molecular:401.46APJ receptor agonist 6
CAS:<p>APJ receptor agonist 6 is a potent agonist of the APJ (apelin receptor) (Ki: 0.059 μM). (EC50: 6.22 μM).</p>Fórmula:C29H34FN3O5Forma y color:SolidPeso molecular:523.6Puupehenone
CAS:<p>Puupehenone is a natural Hsp90 inhibitor boosting caspofungin against resistant fungi, hindering genes for cell wall stress adaptation.</p>Fórmula:C21H28O3Forma y color:SolidPeso molecular:328.45IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Forma y color:SolidPeso molecular:406.48Androgen receptor degrader-1
CAS:<p>Androgen Receptor Degrader-1 (Compound 18) is a potent agent for androgen receptor degradation, applicable in cancer research [1].</p>Fórmula:C15H14ClN3O4Pureza:98%Forma y color:SolidPeso molecular:335.74RO5068760
CAS:<p>RO5068760, a selective MEK1/2 inhibitor, effectively targets a range of tumors, particularly B-RafV600E mutants, with an IC50 of 0.025 μM.</p>Fórmula:C28H27FIN3O6Forma y color:SolidPeso molecular:647.43BMS-604992
CAS:<p>EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist.</p>Fórmula:C24H32ClN7O5Forma y color:SolidPeso molecular:534.01VT-1598 tosylate
CAS:<p>VT-1598 tosylate is a selective, orally active antifungal compound that targets CYP51. It demonstrates efficacy against C. auris.</p>Fórmula:C38H28F4N6O5SForma y color:SolidPeso molecular:756.72KRIBB3
CAS:<p>KRIBB3: novel anticancer microtubule inhibitor; halts MDA-MB-231 cell migration/invasion by targeting Hsp27 phosphorylation.</p>Fórmula:C19H19NO4Forma y color:SolidPeso molecular:325.36Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Fórmula:C16H24ClNO2Forma y color:SolidPeso molecular:297.82BMT-108908
CAS:<p>BMT-108908 is a Negative Allosteric Modulator. It is selective for the NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains.</p>Fórmula:C22H25FN2O2Forma y color:SolidPeso molecular:368.44L 702958
CAS:<p>L 702958 is one kind of spirobenzopyran piperidine.</p>Fórmula:C25H28ClN3O4SForma y color:SolidPeso molecular:502.03STING-IN-7
CAS:<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Fórmula:C16H14ClN3OPureza:98%Forma y color:SolidPeso molecular:299.76APJ receptor agonist 5
CAS:<p>Potent oral APJ agonist (EC 50:0.4 nM); improves cardiac function in HF, with good pharmacokinetics and safety.</p>Fórmula:C26H29N3O6Forma y color:SolidPeso molecular:479.52mGluR5 antagonist-1
CAS:<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41Merodantoin
CAS:<p>Merodantoin induces apoptosis in KRAS-mutant cancer cells via ROS-autophagy and Akt pathway.</p>Fórmula:C11H18N2O2SPureza:99.8%Forma y color:SolidPeso molecular:242.34(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Fórmula:C15H19F2N3OPureza:98%Forma y color:SolidPeso molecular:295.33CB 65
CAS:<p>CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.</p>Fórmula:C22H28ClN3O3Pureza:98.73%Forma y color:SolidPeso molecular:417.93RIPK3-IN-4
CAS:<p>RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage.</p>Fórmula:C24H18BrFN4O3SPureza:98%Forma y color:SolidPeso molecular:541.39Monofluoromethylagmatine
CAS:<p>Monofluoromethylagmatine is an arginine decarboxylase inhibitor.</p>Fórmula:C6H15FN4Forma y color:SolidPeso molecular:162.21Indinavir, threo-
CAS:<p>Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS.</p>Fórmula:C36H47N5O4Pureza:98%Forma y color:SolidPeso molecular:613.79CDK9-IN-29
CAS:<p>CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.</p>Fórmula:C29H33F2N5O4Pureza:98%Forma y color:SolidPeso molecular:553.6DW10075
CAS:<p>DW10075, a novel potent and highly selective inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo.</p>Fórmula:C29H23N5O3Forma y color:SolidPeso molecular:489.52CRTH2-IN-1
CAS:<p>CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.</p>Fórmula:C21H21FN2O4SPureza:98%Forma y color:SolidPeso molecular:416.47Bisnorcymserine
CAS:<p>Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).</p>Fórmula:C21H25N3O2Pureza:98%Forma y color:SolidPeso molecular:351.44A-357300
CAS:<p>A-357300: potent reversible MetAP2 inhibitor, IC50=0.12 uM; promising for neuroblastoma treatment.</p>Fórmula:C15H22ClN3O3SForma y color:SolidPeso molecular:359.87sPLA2 inhibitor 1
CAS:<p>KH064 is a sPLA2-IIA inhibitor of oral activity.</p>Fórmula:C31H37NO4Forma y color:SolidPeso molecular:487.63PF-04957325
CAS:<p>PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.</p>Fórmula:C14H15F3N8OSPureza:99.02%Forma y color:SolidPeso molecular:400.38TC-I 15
CAS:<p>α2β1 integrin inhibitor</p>Fórmula:C23H28N4O6S2Pureza:98%Forma y color:SolidPeso molecular:520.62ATR-IN-5
CAS:<p>ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair.</p>Fórmula:C27H32F3N9OForma y color:SolidPeso molecular:555.6WAY-313201
CAS:<p>WAY-313201 is an active molecule.</p>Fórmula:C18H14FN3O2SForma y color:SolidPeso molecular:355.39MLN-3897
CAS:<p>MLN-3897 is an oral CCR1 antagonist, Ki 2.3 nM, blocks 125I-MIP-1α binding, and inhibits Akt signaling in MM cells.</p>Fórmula:C30H31ClN2O4Pureza:98.62%Forma y color:SolidPeso molecular:519.03Flamprop-methyl
CAS:<p>Flamprop-methyl is a post-emergence herbicide, it is usually used on wild oats.</p>Fórmula:C17H15ClFNO3Pureza:98%Forma y color:SolidPeso molecular:335.76Bcl-2-IN-11
CAS:<p>Bcl-2-IN-11 (compound 6) is a potent and selective inhibitor of Bcl-2 activity, exhibiting an IC50 of 0.9 nM, and demonstrates minimal inhibition against Bcl-xl</p>Fórmula:C45H49ClFN7O8SForma y color:SolidPeso molecular:902.43Lepadin H
CAS:<p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>Fórmula:C26H45NO3Pureza:98%Forma y color:SolidPeso molecular:419.64GPR3 agonist-2
CAS:<p>GPR3 agonist-2 (compound 32) is a potent full agonist of the G protein-coupled receptor 3 (GPR3), exhibiting an IC50 value of 260 nM [1].</p>Fórmula:C14H7F6IO4SForma y color:SolidPeso molecular:512.16Cochliodone A
CAS:<p>Cochliodone A, a bioactive compound isolated from the deep-sea fungus Chaetomium sp., exhibits both antibacterial and anticancer properties.</p>Fórmula:C34H38O12Forma y color:SolidPeso molecular:638.66INT-777 R-enantiomer
CAS:<p>INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.</p>Fórmula:C27H46O5Pureza:98%Forma y color:SolidPeso molecular:450.65SMYD3-IN-1
CAS:<p>SMYD3-IN-1 is an irreversible and selective SMYD3 (SET and MYND domain containing 3) inhibitor(IC50 of 11.7 nM).</p>Fórmula:C28H31ClN4O3Pureza:98%Forma y color:SolidPeso molecular:507.02Famitinib malate
CAS:<p>Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.</p>Fórmula:C27H33FN4O7Forma y color:SolidPeso molecular:544.57ML-099
CAS:<p>ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.</p>Fórmula:C14H13NO2SPureza:99.73%Forma y color:SolidPeso molecular:259.32HPK1-IN-9
CAS:<p>HPK1-IN-9: Potent MAP4K family kinase inhibitor targeting hematopoietic progenitor cells; potential in HPK1 diseases. (Patent WO2021213317A1)</p>Fórmula:C30H33N7O2Forma y color:SolidPeso molecular:523.63A 69992
CAS:<p>A 69992 is an HIV anti-infective nucleoside.</p>Fórmula:C11H14N5O3TPureza:98%Forma y color:SolidPeso molecular:267.28Diethyl-pythiDC
CAS:<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Fórmula:C14H14N2O4SPureza:99.98%Forma y color:SolidPeso molecular:306.34Phenylbenzothiazole-PEG4-OH
CAS:<p>Phenylbenzothiazole-PEG4-OH (compound 1) has therapeutic potential for spinal cord injury and may enhance spine formation [1].</p>Fórmula:C21H25NO5SForma y color:SolidPeso molecular:403.49Eeyarestatin I
CAS:<p>Eeyarestatin I blocks ER protein degradation, hinders p97/atx3 processes, and induces anticancer proteins.</p>Fórmula:C27H25Cl2N7O7Pureza:98% - 98.99%Forma y color:SolidPeso molecular:630.44TA-606
CAS:<p>TA-606 is an angiotensin type 1 receptor antagonist with antihypertensive activity.</p>Fórmula:C33H40ClN7O6Forma y color:SolidPeso molecular:666.17MetAP2-IN-1
CAS:<p>MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].</p>Fórmula:C8H6BrN3Pureza:98%Forma y color:SolidPeso molecular:224.06
