Beta-bloqueante
Los betabloqueantes, también conocidos como agentes bloqueadores beta-adrenérgicos, son compuestos que bloquean la acción de la epinefrina (adrenalina) en los receptores beta, lo que reduce la frecuencia cardíaca y la presión arterial. A menudo se utilizan para tratar afecciones como la hipertensión, las arritmias y la insuficiencia cardíaca. En CymitQuimica, ofrecemos una variedad de betabloqueantes para fines de investigación en estudios cardiovasculares y clínicos.
Subcategorías de "Beta-bloqueante"
Se han encontrado 1520 productos de "Beta-bloqueante"
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4-Hydroxy Nebivolol, Hydrochloride Hydrate(Mixture of Diastereomers)
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Nebivolol.<br>References Stoleru, L., et al.: J. Cardiovasc. Pharmacol., 22, 183 (1993), Cockcroft, J., et al.: J. Pharmacol. Exp. Ther., 274, 1067 (1995), Stoschitzky, K., et al.: Cardiovasc. Drugs Ther., 16, 133 (2002), Poole-Wilson, P., et al.: Lancet, 362, 7 (2003),<br></p>Fórmula:C22H28ClF2NO6Forma y color:NeatPeso molecular:475.91Pindolol
CAS:<p>Applications Mixed β-adrenergic blocker and serotonin 5HT1A-receptor antagonist. Antihypertensive; antianginal; antiarrhythmic; antiglaucoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dreshfield, L. J., et al.: Neurochem. Res., 21, 557 (1996); Perez, V., et al.: Lancet, 349, 1594 (1997)<br></p>Fórmula:C14H20N2O2Forma y color:White To Off-WhitePeso molecular:248.323”-Hydroxy Simvastatin
CAS:Producto controladoFórmula:C25H38O6Forma y color:NeatPeso molecular:434.57Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt is a metabolite of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993),<br></p>Fórmula:C24H23FNNaO3Forma y color:NeatPeso molecular:415.43Carvedilol-d5
CAS:Producto controlado<p>Applications Carvedilol-d5 is the labelled analog of Carvedilol, a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>Fórmula:C24H21D5N2O4Forma y color:NeatPeso molecular:411.51O-Desmethyl Carvedilol
CAS:Producto controlado<p>Applications A metabolite of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Fórmula:C23H24N2O4Forma y color:NeatPeso molecular:392.45rac-4-Hydroxy Propranolol Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications rac-4-Hydroxy Propranolol Hydrochloride is a metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Fórmula:C16H21NO3·ClHForma y color:NeatPeso molecular:311.80Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Fórmula:C20H24N2O3SForma y color:White To BrownPeso molecular:372.48Dabigatran Carboxamide Ethyl Ester
CAS:<p>Applications Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor.<br>References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)<br></p>Fórmula:C27H28N6O4Forma y color:Off-WhitePeso molecular:500.553-Hydroxy Carvedilol
CAS:Producto controlado<p>Applications A vascularly inactive metabolite of Carvedilol (C184625). A novel antihypertensive agent, is a potent antioxidant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Rapola, J., et al.: Lancet, 349, 1715 (1997), Gao, F., et al.: Eur. J. Pharmacol., 406, 109 (2000),<br></p>Fórmula:C24H26N2O5Forma y color:NeatPeso molecular:422.47Atorvastatin Methyl Ester
CAS:Producto controlado<p>Applications Atorvastatin impurity. Atorvastatin Methyl Ester<br>References Graul, A., et al.: Drugs Future, 22, 956 (1997),<br></p>Fórmula:C34H37FN2O5Forma y color:White To Off-WhitePeso molecular:572.67Eplerenone Hydroxyacid Potassium Salt
CAS:Producto controlado<p>Applications A metabolite of Eplerenone. Used in combination therapy for treatment of cardiovascular disorders.<br>References Staessen, J., et al.: J. Endocrinol., 91, 457 (1981), de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), MacFadyen, R., et al.: Cardiovasc. Res., 35, 30 (1997),<br></p>Fórmula:C24H31O7·KForma y color:Off-White To Light YellowPeso molecular:470.60Atenolol
CAS:Producto controlado<p>Applications Cardioselective β-adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic (class II).<br>References Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984),<br></p>Fórmula:C14H22N2O3Forma y color:WhitePeso molecular:266.34Carvedilol-d3
CAS:Producto controladoFórmula:C242H3H23N2O4Forma y color:Off WhitePeso molecular:409.493-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS:Producto controlado<p>Impurity Metoprolol EP Impurity D<br>Applications 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol (Metoprolol EP Impurity D) is a new byproduct detected in Metoprolol tartrate. Metoprolol (M338790) impurity.<br>References Erickson, M., et al.: J. Pharmac. Biomed. Anal., 13, 567 (1995),<br></p>Fórmula:C12H18O4Forma y color:WhitePeso molecular:226.27O-Methyl Atorvastatin Calcium Salt
CAS:Producto controlado<p>Impurity Atorvastatin EP Impurity G<br>Applications Atorvastatin derivative.<br></p>Fórmula:C34H36FN2O5·CaForma y color:Off-WhitePeso molecular:1183.39Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C98H137N23O34•xC2HF3O2Forma y color:NeatPeso molecular:2181.27Befunolol
CAS:Producto controlado<p>Applications Befunolol is a β-adrenergic blocker with an intrinsic sympathomimetic action. But it can work as a β-adrenergic partial agonist in isolated organs.<br>References Nakano, J., et al.: Chem. Pharm. Bull., 36, 1399 (1988); Takayanagi, I., et al.: Gen. Pharmacol., 20, 417 (1989); Koike, K., et al.: Gen. Pharmacol., 25, 1477 (1994)<br></p>Fórmula:C16H21NO4Forma y color:White To Off-WhitePeso molecular:291.34
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