Hormonas en Proteínas Recombinantes

<p>Applications A labelled metabolite of 17β-Nandrolone (N315000).<br>References Dumasia, M., et al.: Xenobiotica, 14, 647 (1984), Schanzer, W., et al.: Clin. Chem., 42, 1001 (1996), Hartmann, C., et al.: J. Pharm. Biomed. Anal., 17, 193 (1998),<br></p>

<p>Applications 17α-Methyl-5α-androstane-2β,3α,17β)-triol is a derivative of Madol (M108000, which is an anabolic steroid recently identified to be misused as a doping agent. The potency of Madol (DMT) to transactivate androgen receptor (AR) dependent reporter gene expression was two times lower as compared to dihydrotestosterone (DHT).<br>References Zierau, O., et al.: Planta Med., 69, 856 (2003), Takahashi, M., et al.: Endocr. J., 51, 425 (2004), Labrie, F., et al.: J. Endocrinol., 184, 427 (2005),Friedel, A., et al.: Toxicol. Lett., 164, 16(2006),<br></p>

<p>Stability Acid Sensitive<br>Applications 17β-(Trimethylsiloxy)testosterone is an anabolic steriod, and a derivative compound of Testosterone (T155000), Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Testerone is a controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>

<p>Applications 5α-Pregnane-3-one-20α-ol, is a steroid metabolome, that can be used for in studies of a possible tool for laboratory diagnosis of schizophrenia. It is also a metabolite of Progesterone (P755900) in adipose cells.<br>References Bicikova, M., et al.: J. Steriod Biochem. Mol. Bio., 77, 133 (2013); Zhang, Y., et al.: Mol. Cell. Endocrinology, 298, 76 (2009);<br></p>

<p>Applications Testosterone-2,2,4,6,6-d5 Propionate is a useful isotopically labeled compound of Testosterone Propionate (T155045)<br></p>

<p>Applications Androstenedione (A637550) analog, an aromatase inhibitor.<br>References Marsh, D.A., et al.: J. Med. Chem., 28, 788 (1985),<br></p>

<p>Applications Testosterone-2,2,4,6,6-d5 Acetate is a useful isotopically labeled compound of Testosterone 17-O-Acetate (T155025)<br></p>

<p>Applications Testosterone-2,2,4,6,6-d5 Heptanoate is a useful isotopically labeled compound of Testosterone Enanthate (T155080)<br></p>

<p>Applications Testosterone-2,2,4,6,6-d5 Benzoate is a useful isotopically labeled compound of Testosterone Benzoate (T155015)<br></p>

<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>

<p>Applications Testosterone-16,16,17-d3 Hexanoate is a useful isotopically labeled compound of Testosterone Hexanoate (T155125)<br></p>

<p>Applications 4-Androsten-17alpha-methyl-17beta-ol-3-one-1,2-d2 is a useful isotopically labeled compound of 17α-Methyl Testosterone (M326400)<br></p>

<p>Applications 5-Androstenediol is a steroid androgen metabolite of Testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Miller, M., et al.: Steroids., 78, 15 (2013); Baker, M.E., et al.: Steroids., 77, 1192 (2012); Ronis, M.J.J. et al.: Comp. Biochem. Physiol.-C: Pharmacol. Toxicol. Endocrinol., 121C, 221 (1998);<br></p>

<p>Applications Dydrogesterone (D826000) intermediate. Used in the preparation of 10α-steroids.<br></p>