Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 172 productos de "Sistema complementario"
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Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Forma y color:Lyophilized PowderPeso molecular:87.0 kDa (predicted)Ref: TM-TMPH-02607
1mg2.350,00€5µg106,00€10µg171,00€20µg276,00€50µg418,00€100µg566,00€200µg875,00€500µg1.554,00€C1QA Protein, Mouse, Recombinant (E. coli, His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Pureza:98% - > 85% as determined by SDS-PAGEForma y color:Lyophilized PowderPeso molecular:29.1 kDa (predicted)Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:14.0 kDa (predicted)Ref: TM-TMPH-03270
1mg2.350,00€5µg130,00€10µg211,00€20µg351,00€50µg520,00€100µg714,00€200µg1.027,00€500µg1.607,00€Complement factor I Protein, Rat, Recombinant (His & Myc)
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag.Forma y color:Lyophilized PowderPeso molecular:69.2 kDa (predicted)Ref: TM-TMPH-03273
5µg172,00€10µg285,00€20µg478,00€50µg888,00€100µg1.439,00€200µg1.625,00€500µg1.997,00€C1SB Protein, Mouse, Recombinant (His & Myc)
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.Forma y color:Lyophilized PowderPeso molecular:82.4 kDa (predicted)Ref: TM-TMPH-02603
1mg2.350,00€5µg130,00€10µg211,00€20µg351,00€50µg520,00€100µg714,00€200µg1.027,00€500µg1.607,00€Empasiprubart
CAS:Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaNRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Fórmula:C20H17ClN6OS2Forma y color:SolidPeso molecular:456.97C5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Fórmula:C62H111N11O12Forma y color:SolidPeso molecular:1202.61BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Fórmula:C14H10N2O2S2Pureza:98%Forma y color:SolidPeso molecular:302.37FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Fórmula:C23H23NO4Pureza:98.85%Forma y color:SolidPeso molecular:377.43Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:98.27%Forma y color:SolidPeso molecular:444.52Ref: TM-T10863
1mg96,00€5mg172,00€10mg250,00€25mg385,00€50mg512,00€100mg695,00€200mg888,00€1mL*10mM (DMSO)190,00€C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.
Fórmula:C27H35N3O2Pureza:99.76%Forma y color:SolidPeso molecular:433.59NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Fórmula:C36H35N3O4Pureza:99.21%Forma y color:SolidPeso molecular:573.68EG00229
CAS:EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.Fórmula:C19H20F3N7O7S3Pureza:98.23%Forma y color:SolidPeso molecular:611.6Ref: TM-T11153
1mg46,00€5mg94,00€10mg148,00€25mg239,00€50mg353,00€100mg525,00€200mg750,00€1mL*10mM (DMSO)133,00€Factor D inhibitor 6
CAS:Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.Fórmula:C23H22ClFN6O3Forma y color:SolidPeso molecular:484.92Factor B-IN-2
CAS:Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.Fórmula:C25H32N2O4Forma y color:SolidPeso molecular:424.53W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Fórmula:C30H37ClN2O2Pureza:96.8%Forma y color:SolidPeso molecular:493.08Ref: TM-T17250
1mg80,00€5mg120,00€10mg177,00€25mg304,00€50mg492,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)157,00€EG01377
CAS:EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.Fórmula:C26H30N6O6S2Pureza:98%Forma y color:SolidPeso molecular:586.68C5aR-IN-1
CAS:C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.Fórmula:C36H39F4N3O2Forma y color:SolidPeso molecular:621.71
