Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 156 productos de "Sistema complementario"
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Complement C5 Protein, Human, Recombinant (Flag)
<p>Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag.</p>Forma y color:Lyophilized PowderPeso molecular:187.36 kDa (predicted); 176.6 kDa, 100.87 kDa and 72.07 kDa (reducing conditions)(Z)-Leukadherin-1
CAS:<p>(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.</p>Fórmula:C22H15NO4S2Pureza:99.23%Forma y color:SolidPeso molecular:421.49Complement C2 Protein, Human, Recombinant (His)
<p>Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.6%Forma y color:Lyophilized PowderPeso molecular:82.5 kDa (predicted)MASP2 Protein, Mouse, Recombinant (His)
<p>MASP2 Protein, Mouse, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.C1s Protein, Human, Recombinant (His)
<p>Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.</p>Forma y color:Lyophilized PowderPeso molecular:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)Complement C8 γ Protein, Human, Recombinant (His)
<p>Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.</p>Forma y color:Lyophilized PowderPeso molecular:22 KDa (reducing condition)MASP2 Protein, Rat, Recombinant (E. coli, His)
<p>MASP2 Protein, Rat, Recombinant (E.</p>Forma y color:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.MBL2 Protein, Human, Recombinant (His)
<p>Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.</p>Pureza:> 99.9% - > 99.9%Forma y color:Lyophilized PowderPeso molecular:31 KDa (reducing condition)Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Forma y color:Lyophilized PowderPeso molecular:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
<p>Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.</p>Forma y color:Lyophilized PowderPeso molecular:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)MASP2 Protein, Human, Recombinant (His)
<p>The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.</p>Forma y color:Lyophilized PowderPeso molecular:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QBP Protein, Mouse, Recombinant (His)
<p>C1QBP Protein, Mouse, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:24.7 kDa (predicted); 32 kDa (reducing conditions)Complement C5a Protein, Mouse, Recombinant, Biotinylated
<p>Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:9 kDa (predicted)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
<p>Expression system: HEK293 Cells<br>Length: 25-1663, Full Length of Mature Protein<br>Activity: Not Tested</p>Forma y color:Lyophilized PowderPeso molecular:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)Complement C7 Protein, Human, Recombinant (His)
<p>Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:92.6 kDa (predicted); 92-98 kDa (reducing conditions)Complement factor I Protein, Human, Recombinant (His)
<p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>Forma y color:Lyophilized PowderPeso molecular:64.58 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
<p>MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.</p>Forma y color:Lyophilized PowderPeso molecular:95-120 KDa (reducing condition)MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
<p>MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.CFI Protein, Mouse, Recombinant (His)
<p>CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:66.75 kDa (predicted); 126.1 kDa, 59.3 kDa and 46.7 kDa (reducing conditions)MBL1 Protein, Rat, Recombinant (hFc)
<p>MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:50.5 kDa (predicted); 56 kDa (reducing conditions)MASP2 Protein, Cynomolgus, Recombinant (His)
<p>MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result.C1QTNF1 Protein, Human, Recombinant (His)
<p>C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain.</p>Forma y color:Lyophilized PowderPeso molecular:37 KDa (reducing condition)C1s-A subcomponent Protein, Mouse, Recombinant (His)
<p>C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:76.6 kDa (predicted)Complement C3a Protein, Mouse, Recombinant
<p>Complement C3a Protein, Mouse, Recombinant is expressed in E.</p>Pureza:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)Forma y color:Lyophilized PowderPeso molecular:9 KDa (reducing condition)Complement C3 Protein, Human, Recombinant (His)
<p>Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:SDS-PAGE: 93.4%; SEC-HPLC: 94.7% - SDS-PAGE: 95.5%; SEC-HPLC: 92.6%Forma y color:Lyophilized PowderPeso molecular:186.43 kDa (predicted)Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Forma y color:Lyophilized PowderPeso molecular:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.Complement Factor D/CFD Protein, Human, Recombinant (hFc)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Forma y color:Lyophilized PowderPeso molecular:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.Complement C5 Protein, Human, Recombinant (His & FLAG)
<p>Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.</p>Pureza:96.1%Forma y color:Lyophilized PowderPeso molecular:188.8 kDa (predicted)Complement C3 Protein, Cynomolgus, Recombinant (His)
<p>Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:90.3%Forma y color:Lyophilized PowderPeso molecular:186.40 kDa (predicted)Complement C3a Protein, Human, Recombinant
<p>Complement C3a Protein, Human, Recombinant is expressed in E.</p>Pureza:>99.99% - Greater than 95% as determined by reducing SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:13 KDa (reducing condition)Complement C5 Protein, Cynomolgus, Recombinant
<p>Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.</p>Forma y color:Lyophilized PowderPeso molecular:8.41 kDa (predicted); 12.42 kDa (reducing conditions)Complement C2 Protein, Human, Recombinant (hFc)
<p>Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:110 kDa (predicted); 110-130 kDa (reducing condition, due to glycosylation)Complement C7 Protein, Human, Recombinant (hFc)
<p>Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:118 kDa (predicted); 118 kDa (reducing conditions)Complement factor I Protein, Mouse, Recombinant (His)
<p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>Forma y color:Lyophilized PowderPeso molecular:66.39 kDa (predicted). Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Tris-Bis PAGE result.Complement C5a Protein, Mouse, Recombinant
<p>Complement C5a Protein, Mouse, Recombinant is expressed in E.</p>Pureza:97.4%Forma y color:Lyophilized PowderPeso molecular:9 kDa (predicted)Complement C5 Protein, Cynomolgus, Recombinant (His)
<p>Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)Complement C2 Protein, Cynomolgus, Recombinant (His)
<p>Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).</p>Forma y color:Lyophilized PowderPeso molecular:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement C3 Protein, Mouse, Recombinant (aa 994-1310, His)
<p>Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:36.34 kDa (predicted); 32.39 kDa (reducing conditions)C1QBP Protein, Human, Recombinant (His)
<p>C1QBP Protein, Human, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:24.8 kDa (predicted); 36 kDa (reducing conditions)Compstatin control peptide acetate
CAS:<p>Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.</p>Fórmula:C66H101N23O17Pureza:99.02%Forma y color:Odour SolidPeso molecular:1488.65BCX 1470 methanesulfonate
CAS:<p>BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).</p>Fórmula:C15H14N2O5S3Forma y color:SolidPeso molecular:398.48PMX 53 acetate(219639-75-5 free base)
CAS:<p>PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50</p>Fórmula:C49H69N11O9Pureza:99.91%Forma y color:SolidPeso molecular:956.16Eculizumab
CAS:<p>Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5</p>Pureza:98.20%Forma y color:LiquidPeso molecular:148 kDaADH-503
CAS:<p>ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.</p>Fórmula:C27H28N2O5S2Pureza:97.03% - >99.99%Forma y color:SolidPeso molecular:524.7Danicopan
CAS:<p>Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.</p>Fórmula:C26H23BrFN7O3Pureza:99.94%Forma y color:SolidPeso molecular:580.41JR14a
CAS:<p>JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.</p>Fórmula:C25H26Cl2N4O3SPureza:99.76%Forma y color:SolidPeso molecular:533.47Compstatin
CAS:<p>Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.</p>Fórmula:C66H99N23O17S2Pureza:>99.99%Forma y color:SolidPeso molecular:1550.77Iptacopan hydrochloride
CAS:<p>Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.</p>Fórmula:C25H31ClN2O4Pureza:98.89% - 99.89%Forma y color:SolidPeso molecular:458.98Avacopan
CAS:<p>Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.</p>Fórmula:C33H35F4N3O2Pureza:99.47% - 99.9%Forma y color:SolidPeso molecular:581.64Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Forma y color:SolidPeso molecular:421.49
