Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65495 productos de "Derivados de Quinazolina y Quinolina"
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COTI-219
CAS:<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Fórmula:C17H18N6SForma y color:SolidPeso molecular:338.43Beloranib
CAS:<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Fórmula:C29H41NO6Pureza:98%Forma y color:SolidPeso molecular:499.643-Aminobenzene-1,2-diol
CAS:<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Fórmula:C6H7NO2Forma y color:SolidPeso molecular:125.13Indinavir monohydrate
CAS:<p>Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.</p>Fórmula:C36H49N5O5Forma y color:SolidPeso molecular:631.82Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Fórmula:C20H21Br2N5O4SPureza:98%Forma y color:SolidPeso molecular:587.29Rodatristat
CAS:<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Fórmula:C27H27ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:561.98Tipelukast
CAS:<p>Tipelukast (KCA 757), an oral drug for asthma research, blocks leukotrienes and fights inflammation and fibrosis.</p>Fórmula:C29H38O7SPureza:>99.99%Forma y color:SolidPeso molecular:530.67SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Fórmula:C22H26ClF3N2O7SPureza:98%Forma y color:SolidPeso molecular:554.96RJF02215
CAS:<p>RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.</p>Fórmula:C17H12ClN3OS3Forma y color:SolidPeso molecular:405.95SD-7300
CAS:<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Fórmula:C21H30F3N3O7SForma y color:SolidPeso molecular:525.54BAY-7598
CAS:<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Fórmula:C28H31N3O6Pureza:98%Forma y color:SolidPeso molecular:505.56RuDiOBn
CAS:<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Fórmula:C29H22O7Forma y color:SolidPeso molecular:482.481Thioquinapiperifil dihydrochloride
CAS:<p>Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.</p>Fórmula:C24H29ClN6OSPureza:98.73%Forma y color:SolidPeso molecular:485.05Arterolane
CAS:<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Fórmula:C22H36N2O4Forma y color:SolidPeso molecular:392.53Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Fórmula:C24H23NO5SPureza:99.03%Forma y color:SolidPeso molecular:437.51Vecabrutinib
CAS:<p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>Fórmula:C22H24ClF4N7O2Pureza:99.74%Forma y color:SolidPeso molecular:529.92Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Fórmula:C32H31F9N4O5Pureza:99.26% - >99.99%Forma y color:SolidPeso molecular:722.6Ezetimibe 2-Fluorobenzene Isomer ((3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H21F2NO3Forma y color:White Off-White SolidPeso molecular:409.14895N-Acetyl-L-Leucine (Acetyl-L-leucine)
CAS:Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoiFórmula:C8H15NO3Forma y color:White PowderPeso molecular:173.10519Atazanavir Benzylidenehydrazine Carbamate (Methyl [(S)-1-{[(2S,3S)-3-hydroxy-1-phenyl-4-{1-[4-(pyridin-2-yl)benzyl]-2-[4-(pyridin-2-yl)benzylidene]hydrazinyl}butan-2-yl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamate)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFórmula:C42H46N6O4Forma y color:Light Yellow SolidPeso molecular:698.35805Apremilast R-Enantiomer
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C22H24N2O7SForma y color:White Off-White PowderPeso molecular:460.13042Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H19F2NO3Forma y color:White SolidPeso molecular:407.1333N-Nitroso Dabigatran Etexilate Solution (1 mL ) (ethyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)(nitroso)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate)
CAS:<p>Compounds containing an unfused pyridine ring in the structure, nesoi</p>Fórmula:C34H40N8O6Forma y color:Colorless LiquidPeso molecular:656.30708Levetiracetam acid ((S)-2-(2-oxopyrrolidin-1-yl)butanoic acid)
CAS:<p>Lactams, nesoi</p>Fórmula:C8H13NO3Forma y color:Off-White SolidPeso molecular:171.08954Apremilast
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C22H24N2O7SPeso molecular:460.13042Dasatinib Related Compound A
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C22H26ClN7O3SPeso molecular:503.15064Salmeterol Related Compound B (4-{1-Hydroxy-2-[6-(4-phenylbutan-2-yloxy)hexylamino]ethyl}-2-
CAS:<p>Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function</p>Fórmula:C25H37NO4Forma y color:Off-White Crystalline PowderPeso molecular:415.27226Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFórmula:C16H17N3O2SForma y color:White Off-White SolidPeso molecular:315.10415Methoxyamiodarone ([2-[(1RS)-1-Methoxybutyl]benzofuran-3-yl][4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone) (DISCONTINUED)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C26H31I2NO4Forma y color:Colorless GelPeso molecular:675.03425Ezetimibe Tetrahydropyran Analog ((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C24H21F2NO3Forma y color:White Off-White SolidPeso molecular:409.14895Apremilast Related Compound E
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C22H24N2O7SForma y color:Pale Yellow PowderPeso molecular:460.13042Rivaroxaban Open Ring ((R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C18H20ClN3O4SForma y color:Off-White SolidPeso molecular:409.89(4-Methylbenzoyl)trifluoroacetone (1,1,1-Trifluoro-4-hydroxy-4-(4-methylphenyl)-3-buten-2-one)
CAS:Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoiFórmula:C11H9F3O2Forma y color:White SolidPeso molecular:230.05546Chlorothiophene carboxylic acid (5-chlorothiophene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C5H3ClO2SForma y color:Off-White Pale Yellow SolidPeso molecular:162.59 g/molMethylbis(2-pyridylethyl)amine Hydrochloride (N-Methyl-N,N-bis(2-pyridin-2-yl-ethyl)amine trihydrochloride)
CAS:<p>Compounds containing an unfused pyridine ring in the structure, nesoi</p>Fórmula:C15H19N3·3HClForma y color:Light Brown PowderPeso molecular:241.1579N-Nitroso Carvedilol Solution (1 mL ) (N-(3-((9H-carbazol-4-yl)oxy)-2-hydroxypropyl)-N-(2-(2-methoxyphenoxy)ethyl)nitrous amide)
CAS:<p>Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoi</p>Fórmula:C24H25N3O5Forma y color:LiquidPeso molecular:435.17942Everolimus System Suitability Mixture (This is a mixture of Everolimus, Everolimus oxepane isomer and 9-O-Hydroxyethyl Sirolimus)
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiForma y color:White Yellow PowderDasatinib
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C22H26ClN7O2S·H2OPeso molecular:505.16629Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H22FNO3Forma y color:White Off-White PowderPeso molecular:391.15837(-)-3,4-Dihydroxynorephedrine
CAS:Fórmula:C9H13NO3Pureza:98%Forma y color:SolidPeso molecular:183.2044Ref: 4Z-L-1777
Producto descatalogadoRef: 4Z-E-4344
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Producto descatalogadoRef: 4Z-L-4224
Producto descatalogadoParoxetine EP Impurity I HCl
CAS:Fórmula:C12H16FNO·HClForma y color:Pale Yellow SolidPeso molecular:209.26 36.46Ref: 4Z-P-0213
Producto descatalogadoRef: 4Z-G-1053
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Producto descatalogadoRef: 4Z-D-157003
Producto descatalogadoTadalafil Impurity 97
CAS:Fórmula:C23H22N4O4Forma y color:White To Off-White SolidPeso molecular:418.45Ref: 4Z-T-10146
Producto descatalogadoRef: 4Z-A-315061
Producto descatalogadoRef: 4Z-L-0329
Producto descatalogadoRef: 4Z-M-269016
Producto descatalogadoRef: 4Z-E-6030
Producto descatalogadoRef: 4Z-F-1414
Producto descatalogadoRef: 4Z-O-02173
Producto descatalogadoRef: 4Z-I-053128
Producto descatalogadoRef: 4Z-E-1041
Producto descatalogadoRef: 4Z-B-1623
Producto descatalogadoRef: 4Z-P-6482
Producto descatalogadoXibornol
CAS:<p>Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。</p>Fórmula:C18H26OForma y color:SolidPeso molecular:258.4Ref: 4Z-O-0880
Producto descatalogadoRef: 4Z-L-1761
Producto descatalogadoRef: 4Z-P-240004
Producto descatalogadoRef: 4Z-A-253028
Producto descatalogado4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic Acid
Fórmula:C20H21ClN2O3Peso molecular:372.85Ref: 4Z-L-1038
Producto descatalogadoRef: 4Z-V-0250
Producto descatalogadoRef: 4Z-R-7310
Producto descatalogadoRef: 4Z-R-080037
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Producto descatalogadoFlupyradifurone-d5 (Major)
CAS:Fórmula:C12H6D5ClF2N2O2Forma y color:White To Off-White SolidPeso molecular:293.71Ref: 4Z-A-243
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Producto descatalogadoIrbesartan Impurity 17-d4
CAS:Fórmula:C25H23D4N7O2Forma y color:White To Off-White SolidPeso molecular:461.56Ref: 4Z-I-0242
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Producto descatalogadoLenalidomide Impurity 30
Fórmula:C25H33N3O13Forma y color:White To Off-White SolidPeso molecular:583.55Ref: 4Z-L-2637
Producto descatalogado2,2,3,3,5,5,6,6-Octafluoro-4-(1,1,2,2,3,3,3-heptafluoropropyl) Morpholine
CAS:Fórmula:C7F15NOPeso molecular:399.06Ref: 4Z-M-208013
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Producto descatalogadoBalsalazide Impurity 6
CAS:Fórmula:C20H19N6O6·ClForma y color:Dark Orange SolidPeso molecular:439.41 35.45Ref: 4Z-B-3014
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Producto descatalogadoBupropion Impurity ((3R,5RS,6RS)-6-(3-Chlorophenyl)-6-Hydroxy-5-Methyl-3-Thiomorpholine Carboxylic Acid)
Fórmula:C12H14ClNO3SPeso molecular:287.77Ref: 4Z-B-0516
Producto descatalogadoKetamine EP Impurity A (E-Isomer) HCl (Ketamine USP Related Compound A (E-Isomer) HCl)
CAS:Fórmula:C13H16ClNO·HClForma y color:White To Off-White SolidPeso molecular:237.73 36.46Ref: 4Z-K-018001
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CAS:Fórmula:C25H27NO2Forma y color:White To Off-White SolidPeso molecular:373.50Ref: 4Z-T-017
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Producto descatalogado
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