Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65562 productos de "Derivados de Quinazolina y Quinolina"
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Nitrendipine Dipropyl Ester
CAS:<p>Applications Nitrendipine Dipropyl Ester is an analogue of the antihypertensive drug Nitrendipine (N490150). Also, Nitrendipine Dipropyl Ester is an impurity of antihypertensive Lercanidipine (L179000). Lercanidipine impurity B.<br>References Meyer, H., et al.: Arzneim.-Forsch., 31, 407 (1981),<br></p>Fórmula:C21H24N2O6Forma y color:NeatPeso molecular:400.42Carvedilol-d5
CAS:Producto controlado<p>Applications Carvedilol-d5 is the labelled analog of Carvedilol, a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>Fórmula:C24H21D5N2O4Forma y color:NeatPeso molecular:411.51Desfluoro Risperidone
CAS:Producto controlado<p>Impurity Risperidone EP Impurity K<br>Applications Desfluoro Risperidone (Risperidone EP Impurity K) is a Risperidone (R525000) impurity, as antipsychotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C23H28N4O2Forma y color:NeatPeso molecular:392.49Raltegravir-d3 b-D-Glucuronide (>90%)
CAS:Producto controlado<p>Applications A labelled metabolite of Raltegravir.<br>References Bosma, P., et al.: J. Biol. Chem., 269, 17960 (1994) , Richman, D., et al.: Nature, 410, 995 (2001), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006),<br></p>Fórmula:C26H26D3FN6O11Pureza:>90%Forma y color:NeatPeso molecular:623.56Lansoprazole
CAS:<p>Applications Used as a gastric proton pump inhibitor. An antiulcerative. May limit the severity of tuberculosis (see Chem. and Eng. News. p. 28 July 20 (2018)).<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006), Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Fórmula:C16H14F3N3O2SForma y color:White To Light BeigePeso molecular:369.364,7-dimethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718754-(2-Aminoanilino)pyridine
CAS:Producto controlado<p>Applications An intermediate used to prepare Timiperone as well as cyclooxygenase-2 inhibitors and adrenergic agents<br>References Eftink, M.R., et al.: J. Phys. Chem., 99, 5713 (1995), Palmer, B.D., et al.: J. Med. Chem., 41, 5457 (1998), Pinto, I., et al.: J. Med. Chem., 51, 7205 (2008),<br></p>Fórmula:C11H11N3Forma y color:NeatPeso molecular:185.234-(3,5-dimethyl-1H-pyrazol-1-yl)benzenesulfonyl chloride
CAS:Forma y color:SolidPeso molecular:270.7300109863281(Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications (Z,Z)-5-(2-Methyl-3-phenyl-propenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic Acid is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985), Qi, M. et al.: J. Beij, Inst. Tech., 13, 445 (2004);<br></p>Fórmula:C15H13NO3S2Forma y color:Yellow-Red SolidPeso molecular:319.4Isradipine
CAS:Producto controlado<p>Applications Isradipine is a dihydropyridine calcium channel blocker. Antihypertensive and antianginal.<br>References Nelson, E.B., et al.: Clin. Pharmacol. Ther., 40, 694 (1986); Hof, R.P., et al.: J. Cardiovasc. Pharmacol., 8, 221 (1986);<br></p>Fórmula:C19H21N3O5Forma y color:NeatPeso molecular:371.395-tert-Butyl-1-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid
CAS:Fórmula:C14H15N3O4Pureza:98%Forma y color:SolidPeso molecular:289.2912-[5-chloro-2-(pyridin-3-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:308.20999145507811-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Fórmula:C17H18N4Forma y color:Light Yellow To BrownPeso molecular:278.35N-Boc-N-deshydroxyethyl Dasatinib
CAS:Producto controlado<p>Applications N-Boc-N-deshydroxyethyl Dasatinib (cas# 1159977-13-5) is a compound useful in organic synthesis. It is a COVID19-related research product.<br></p>Fórmula:C25H30ClN7O3SForma y color:Off White To Light YellowPeso molecular:544.07Metaraminol Bitartrate
CAS:Producto controlado<p>Applications Metaraminol Bitartrate is a vasopressor comparable to ephedrine used in the maintenance of arterial pressure during spinal anesthesia. Also used in the treatment of hypotension while under the effect of anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ngan, K. et al.: Anesthes., 95, 307 (2001); Critchley, L. et al.: Br. J. Anaesth., 76, 734 (1996);<br></p>Fórmula:C9H13NO2·C4H6O6Forma y color:WhitePeso molecular:317.294”-trans-Hydroxy Cilostazol
CAS:Producto controlado<p>Applications A metabolite of Cilostazol.<br>References de Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994), Tata, P; J Pharm Biomed Anal 2001, 24, 381 ,Hiratsuka, M; Eur J Clin Pharmacol 2002, 58, 417 ,,Roy, J; Drug Metab Dispos 2005, 33, 884<br></p>Fórmula:C20H27N5O3Forma y color:NeatPeso molecular:385.46Nitisinone
CAS:<p>Applications Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.<br>References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),<br></p>Fórmula:C14H10F3NO5Forma y color:NeatPeso molecular:329.232-Amino-5-methylthiazole
CAS:Producto controlado<p>Impurity Meloxicam EP Impurity B<br>Applications 2-Amino-5-methylthiazole (Meloxicam EP Impurity B) is an aminothiazole derivative used in characterization and DNA-interaction studies via formation of metal complexes that bind competitively to DNA. 2-Amino-5-methylthiazole can be used in solar cells to influence the interaction with the TiO2 photoelectrode, which in turn alters the dye-sensitized solar cell performance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kusama, H. et al.: Sol. Energy Mat. Sol. Cells, 82, 457 (2004); Cox, P.J. et al.: Bioorg. Med. Chem., 17, 6054 (2009);<br></p>Fórmula:C4H6N2SForma y color:Brown To Dark BrownPeso molecular:114.174-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-a,a-dimethyl-benzeneacetic Acid
CAS:<p>Applications 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic acid is an impurity of fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.<br>References Pratt, E., et al.: Diabet Med., 18, 515 (2001), Mizutani, N., et al.: J. Pharmacol. Sci., 93, 437 (2003), Scadding, G., et al.: Clin. Drug Invest., 25, 153 (2005), Asai, M., et al.: N. Engl. J. Med., 354, 307 (2006),<br></p>Fórmula:C32H37NO3Forma y color:NeatPeso molecular:483.64(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);<br></p>Fórmula:C7H9ClN2OForma y color:NeatPeso molecular:172.612-Cyclopropyl-quinoline-4-carboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:213.23599243164062Reduced Haloperidol-d4
CAS:Producto controlado<p>Applications Labelled Haloperidol Metabolite II<br>References Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006), Sheridan, R., et al.: J. Med. Chem., 50, 3173 (2007), Lee, I., et al.: Eur. J. Pharmacol., 578(2, 123 (2008), Entrena, J., et al.: Psychopharmacol., 205, 21 (2009),<br></p>Fórmula:C21H21D4ClFNO2Forma y color:White To Light YellowPeso molecular:381.9(S)-4-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one
CAS:Pureza:98.0%Peso molecular:479.172417372Retigabine
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A new experimental anticonvulsant drug. Anxiolytic.<br>References Dailey, J.W.; et al.: Neuroscience Lett., 195, 77 (1995), Korsgaard, M.P.G., et al.: J. Pharmacol. Exp. Ther., 314, 1, 282 (2005),<br></p>Fórmula:C16H18FN3O2Forma y color:NeatPeso molecular:303.33DL-Fenfluramine
CAS:Producto controlado<p>Applications Anorectic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pinder, et al.: Drugs, 10, 241 (1975); Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985); Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985);<br></p>Fórmula:C12H16F3NForma y color:NeatPeso molecular:231.26Sodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:97%Peso molecular:405.35000610351562-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:273.30999755859375Triallate
CAS:Producto controlado<p>Applications Triallate is a pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schneider, M., et al.: J. Environ. Qual., 42, 844 (2013); Busi, R., et al.: Pest Manag. Sci., 69, 1379 (2013)<br></p>Fórmula:C10H16Cl3NOSForma y color:Light Brown To BrownPeso molecular:304.66Chlorpromazine N-Oxide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Chlorpromazine N-Oxide is a metabolite of Chlorpromazine. Chlorpromazine exhibits antiadrenergic, antiserotonergic, anticholinergic, and antihistaminergic properties, and commonly used to treat schizophrenia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Z., et al.: Handbook of Metabolic Pathways of Xenobiotics, 3, 1102 (2014); Kigondu, E. M., et al.: MedChemComm, 5, 502 (2014); Yeung, P. K. F., et al.: Eur. J. Clin. Pharmacol., 45, 563 (1993)<br></p>Fórmula:C17H19ClN2OSForma y color:NeatPeso molecular:334.86Ondansetron-d3
CAS:Producto controlado<p>Applications Ondansetron-d3 is a labeled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Fórmula:C18H16D3N3OForma y color:NeatPeso molecular:296.38Ranolazine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Ranolazine Dihydrochloride is an anti-ischemic agent which modulates myocardial metabolism. Antianginal.<br>References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004); McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998); Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002)<br></p>Fórmula:C24H35Cl2N3O4Forma y color:NeatPeso molecular:500.464-Dehydroxy-5-hydroxy Ritonavir
CAS:Producto controlado<p>Impurity Ritonavir EP Impurity N<br>Applications 4-Dehydroxy-5-Hydroxy Ritonavir (Ritonavir EP Impurity N) is an impurity of the selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.<br>References Kempf, D.J. et al.: J. Med. Chem., 41, 602 (1998); Mekapati, S.B. et al.: J. Enzyme Inhib., 16, 185 (2001);<br></p>Fórmula:C37H48N6O5S2Forma y color:NeatPeso molecular:720.94
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