Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65495 productos de "Derivados de Quinazolina y Quinolina"
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1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-3-quinolinecarboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:295.242004394531253-[2-[4-[4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]benzolyl]piperidin-1-yl]ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Producto controlado<p>Impurity Risperidone EP Impurity I<br>Applications 3-[2-[4-[4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]benzolyl]piperidin-1-yl]ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity I) is a Risperidone (R525000) impurity.<br></p>Fórmula:C35H39F2N5O3Forma y color:NeatPeso molecular:615.71TERT-BUTYL METHYL(1-METHYL-1H-PYRAZOL-3-YL)CARBAMATE
CAS:Pureza:95.0%Peso molecular:211.264999389648443-QUINOLINECARBOXYLIC ACID, 7-[(2-AMINOETHYL)AMINO]-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-
CAS:Pureza:97.0%Peso molecular:335.3349914550781Tipranavir
CAS:<p>Applications Nonpeptidic HIV protease inhibitor (NPPI). Antiviral.<br>References Poppe, S.M., et al.: Antimicrob. Agents Chemother., 41, 1058 (1997), McGregor, T.R., et al.: HIV Clin. Trials, 5, 371 (2004), Boffito, M., et al.: J. Clin. Pharmacol., 46, 130 (2006),<br></p>Fórmula:C31H33F3N2O5SForma y color:NeatPeso molecular:602.66Celecoxib-d7
CAS:Producto controlado<p>Applications Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998); Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000); Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000)<br></p>Fórmula:C17D7H7F3N3O2SForma y color:WhitePeso molecular:388.42Brexpiprazole N-Oxide
CAS:Producto controlado<p>Stability Not Stable in DMSO<br>Applications Brexpiprazole N-Oxide is an impurity and potential metabolite of Brexpiprazole (B677385), a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006);<br></p>Fórmula:C25H27N3O3SForma y color:NeatPeso molecular:449.571-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride
Producto controlado<p>Impurity Naratriptan pyridinium Impurity<br>Stability Hygroscopic<br>Applications Naratriptan (N378730) impurity.<br></p>Fórmula:C17H20ClN3O2SForma y color:NeatPeso molecular:365.88Bicalutamide-d4
CAS:Producto controlado<p>Applications Used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0)<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Fórmula:C18H10D4F4N2O4SForma y color:NeatPeso molecular:434.4Felodipine Ester Lactone
CAS:Producto controlado<p>Applications Felodipine Ester Lactone is an intemediate used in the synthesis of Dehydro Felodipine Ester Lactone (D229690), which is a metabolite of Felodipine (F232375).<br>References Wang, S.X. et al.: J. Pharmacol. Exp. Therap., 250, 632 (1989); Baeaernhielm, C. et al.: Drug Metab. Disp., 14, 613 (1986);<br></p>Fórmula:C17H15Cl2NO4Forma y color:NeatPeso molecular:368.21Desmethyl Sibutramine
CAS:Producto controlado<p>Applications Desmethyl Sibutramine is a metabolite of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998); Woolard, J., et al.: J. Pharmacol. Exp. Ther., 308, 1102 (2004); Geranton, S., et al.: Neuropharmacol., 46, 511 (2004)<br></p>Fórmula:C16H24ClNForma y color:Colourless To YellowPeso molecular:265.823-Pyrazin-2-ylpropanoic acid
CAS:Fórmula:C7H8N2O2Pureza:95.0%Forma y color:SolidPeso molecular:152.153Sulpiride N-oxide
CAS:Producto controlado<p>Applications 5-(Aminosulfonyl)-N-[(1-ethyl-1-oxido-2-pyrrolidinyl)methyl]-2-methoxy-benzamide is a Sulpiride impurity and water pollutant.<br>References Bader, T. et al.: Analytical Chemistry, 89, 13219 (2017);<br></p>Fórmula:C15H23N3O5SForma y color:White To Off-WhitePeso molecular:357.434-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}benzaldehyde
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:267.2070007324219Indocyanine Green (~90%)
CAS:Producto controladoFórmula:C43H47N2O6S2·NaPureza:~90%Forma y color:NeatPeso molecular:774.963,5-Dimethyl-2-pyridinemethanol
CAS:Producto controlado<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Fórmula:C8H11NOForma y color:Colourless To BrownPeso molecular:137.179Tert-Butyl 4-(2-morpholino-2-oxoethyl)piperazine-1-carboxylate
CAS:Pureza:98%Peso molecular:313.39801025390625Thiophene-2-carboximidic acid ethyl ester; hydrochloride
CAS:Pureza:95.0%Peso molecular:191.6699981689453Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:95.0%Peso molecular:367.3999938964844Quinoxaline-2-carbonyl chloride
CAS:Pureza:95.0%Forma y color:Solid, No data available.Peso molecular:192.600006103515628-methyl-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:277.3229980468756-Hydroxy-2-naphthaleneacetic Acid
CAS:<p>Applications A metabolite of Nabumetone.<br>References Nobilis, M., et al.: J., Pharm., Biomed., Anal., 32, 641 (2003),<br></p>Fórmula:C12H10O3Forma y color:NeatPeso molecular:202.214-Defluoro 2-Fluoro Flunarizine Dihydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 4-Defluoro 2-Fluoro Flunarizine Dihydrochloride is an impurity of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral).<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984)<br></p>Fórmula:C26H26F2N2HClForma y color:White SolidPeso molecular:404.4923646Roflumilast N-Oxide
CAS:Producto controlado<p>Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Fórmula:C17H14Cl2F2N2O4Forma y color:NeatPeso molecular:419.21N-Deshydroxyethyl Dasatinib-d8
CAS:Producto controladoFórmula:C21D8H15ClN6OSForma y color:White SolidPeso molecular:451.01Edoxaban-d6
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C24H24D6ClN7O4SForma y color:Light Beige To Light BrownPeso molecular:554.092-(4-(Methylsulfonamido)phenoxy)acetic Acid
CAS:Producto controlado<p>Applications 2-(4-(Methylsulfonamido)phenoxy)acetic Acid is a metabolite of antiarrhythmic drug Dofetilide (D525700), which is a is a potassium channel blocker.<br>References Smith, D., et al.: Xenobiotica, 22, 709 (1992); Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992); Walker, D., et al.: Drug Metab. Dispos., 24, 447 (1996); Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999); Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999);<br></p>Fórmula:C9H11NO5SForma y color:NeatPeso molecular:245.25Pimozide
CAS:Producto controlado<p>Applications Pimozide is a D2 dopamine receptor antagonist that binds to the cloned 5-HT7 receptor with high affinity (1,2,3,4). Pimozide is also a Ca2+ channel antagonist. Pimozide is used as an antipsychotic.<br>References (1) Nikonenko, I., et al.: Mol. Pharmacol., 68, 84 (2005) (2) Mariot, P., et al.: J. Biol. Chem., 277, 10824 (2002) (3) Liu, J., et al.: Br. J. Pharmacol., 126, 245 (1999) (4) Santi, C., et al.: J. Neurosci., 22, 396 (2002)<br></p>Fórmula:C28H29F2N3OForma y color:Off-WhitePeso molecular:461.55Flibanserin Hydrochloride
CAS:Producto controlado<p>Applications Flibanserin is a 5-HT1A agonist and 5-HT2A antagonist that is developed for the treatment of hypoactive sexual desire disorder in women (1,2).<br>References 1) Gelez, H., et. al.: (2013) Psychopharmacology 230 :639-52.2) Katz, M., et. al.: (2013) J. Sex. Med. 10, 1807-15<br></p>Fórmula:C20H21F3N4O·ClHForma y color:NeatPeso molecular:426.86Tris(2-ethylhexyl) 4,4',4''-((1,3,5-triazine-2,4,6-triyl)tris(azanediyl))tribenzoate
CAS:Pureza:97.0%Forma y color:Liquid, No data available.Peso molecular:823.0919799804688Ref: 10-F545236
1gA consultar5gA consultar10gA consultar25gA consultar100gA consultar500gA consultar100mgA consultar500mgA consultar2-Oxo-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridine-3-carboxylic acid
CAS:Forma y color:SolidPeso molecular:221.134994506835942-(2-Chloro-phenoxymethyl)-2 H -pyrazole-3-carboxylic acid
CAS:Fórmula:C11H9ClN2O3Forma y color:SolidPeso molecular:252.657-Hydroxy Loxapine
CAS:Producto controlado<p>Applications 7-Hydroxy Loxapine is a metabolite of Loxapine (L472750), a neuroleptic medication used to treat patients with schizophrenia and obsessive compulsive disorder.<br>References Kapur, S., et al.: Am. J. Psychiatry, 154, 1525 (1997); Rivers-Bulkeley, N. & Hollender, M.: Am. J. Psychiat., 139, 1345 (1982)<br></p>Fórmula:C18H18ClN3O2Forma y color:NeatPeso molecular:343.81
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![Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF219014.webp&w=3840&q=75)
