Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65495 productos de "Derivados de Quinazolina y Quinolina"
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(R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5)
CAS:Producto controlado<p>Applications (R)-Crizotinib-d5 (piperidine-3,3,4,5,5-d5) (CAS# 1395950-84-1) is a useful isotopically labeled research compound.<br></p>Fórmula:C21D5H17Cl2FN5OForma y color:NeatPeso molecular:455.36753-Phenyl-1-propanol
CAS:Producto controlado<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Fórmula:C9H12OForma y color:ColourlessPeso molecular:136.19Fingolimod Palmitate Amide
CAS:Producto controlado<p>Applications Fingolimod Palmitate Amide is an impurity of Fingolimod (F805000, HCl salt), a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Fórmula:C35H63NO3Forma y color:NeatPeso molecular:545.88Quinfamide
CAS:Producto controlado<p>Applications Quinfamide is an anti-amebic agent used to treat tropical parasitic infections.<br>References Slighter, R., et al.: Parasitol., 81, 157 (1980), Parthasarathy, P., et al.: Eur. J. Med. Chem., 28, 195 (1993), Padilla, N., et al.: Clin. Drug Invest., 20, 89 (2000),<br></p>Fórmula:C16H13Cl2NO4Forma y color:White To Light BeigePeso molecular:354.18Thiourea
CAS:Producto controlado<p>Applications Thiourea is used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. Thiourea is also used to treat thyrotoxicosis, a hypermetabolic clinical syndrome that is induced by multiple causes (Graves’ disease, hyperthyroidism, etc.).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998)<br></p>Fórmula:CH4N2SForma y color:WhitePeso molecular:76.12Ondansetron Hydrochloride Dihydrate
CAS:Fórmula:C18H19N3O·ClH·2H2OForma y color:Off-WhitePeso molecular:365.85N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride
CAS:Producto controlado<p>Impurity Verapamil EP Impurity A DIHCL<br>Stability Hygroscopic<br>Applications N1,N3-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N1,N3-dimethyl-1,3-propanediamine Dihydrochloride (Verapamil EP Impurity A DIHCL) is an impurity of Verapamil (V125000), a calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)<br></p>Fórmula:C25H38N2O4·2ClHForma y color:NeatPeso molecular:503.51(R)-Timolol
CAS:Producto controlado<p>Impurity Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A<br>Applications (R)-Timolol (Timolol EP Impurity A; Timolol BP Impurity A; Timolol USP Related Compound A) is an antihypertensive agent that increases ocular blood flow and reduces intraocular pressure. (R)-Timolol is an β-adrenergic blocking agent that binds only to nonspecific sites in the particulate fraction of the heart, lungs, and brain.<br>References Rotmensch, H. et al.: J. Clinical. Pharmacol., 33, 544 (1993); Chiou, G. & Chen. Y., J. Ocular. Pharmacol., 8, 183 (1992); Chiou, G. et al.: J. Ocular. Pharmacol., 6, 23 (1990); Tocco, D. et al.: Drug Met. Disposit., 4, 323 (1976)<br></p>Fórmula:C13H24N4O3SForma y color:NeatPeso molecular:316.422-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-Isoquinolinetriol Hemisulfate Hydrate is a salt form of 2-(1,1-Dimethylethyl)-1,2,3,4-tetrahydro-4,6,8-isoquinolinetriol (CAS 94120-05-5) which is used in analytical study of identification of degradation products and process impurities from terbutaline sulfate by UHPLC-Q-TOF-MS/MS and In silico toxicity prediction.<br>References Zhou, N., et al.: Chromatographia, 80, 793 (2017)<br></p>Fórmula:(C13H19NO3)•H2SO4•x(H2O)Forma y color:NeatPeso molecular:2237.3098071802Potassium Phthalimide
CAS:Producto controlado<p>Applications Potassium Phthalimide is a green, solid-base organocatalys.<br>References Kiyani, H., Ghiasi, M.: Chinese Chem. Lett., 25, 313 (2014)<br></p>Fórmula:C8H4NO2·KForma y color:NeatPeso molecular:185.221-[3-(Trifluoromethyl)pyridin-2-yl]piperazine hydrochloride
CAS:Pureza:97.0%Peso molecular:267.679992675781256-Hydroxy-2-naphthaleneacetic Acid
CAS:<p>Applications A metabolite of Nabumetone.<br>References Nobilis, M., et al.: J., Pharm., Biomed., Anal., 32, 641 (2003),<br></p>Fórmula:C12H10O3Forma y color:NeatPeso molecular:202.215''''-Methyl-apixaban
CAS:Producto controlado<p>Impurity Apixaban<br>Applications Analytical standard impurity of drug.<br></p>Fórmula:C26H27N5O4Forma y color:NeatPeso molecular:473.524Ethyl 2-amino-7-hydroxy-4-(pyridin-3-yl)-4H-chromene-3-carboxylate
CAS:Pureza:95.0%Peso molecular:312.32501220703125Lomerizine Dihydrochloride
CAS:Producto controlado<p>Applications A diphenylpiperazine calcium channel blocker. A selective cerebral vasodilator. Antimigraine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kanazawa, T., et al.: J. Cardiovasc. Pharmacol., 16, 430 (1990), Hara, H., et al.: Arch. Int. Pharmacodyn, 304, 206 (1990), Danielisova, V., et al.: Neurochem. Res., 19, 1503 (1994)<br></p>Fórmula:C27H30F2N2O3·2ClHForma y color:NeatPeso molecular:541.462-(1-phenyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid
CAS:Pureza:95.0%Peso molecular:228.2510070800781222-Hydroxy Mifepristone-d6
CAS:Producto controlado<p>Applications A labelled metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H29D6NO3Forma y color:NeatPeso molecular:451.63(S)-2-Aminobutanoic Acid Hydrochloride
CAS:Producto controlado<p>Applications (S)-2-Aminobutanoic Acid Hydrochloride is an intermediate in the synthesis of Levetiracetam (L331500), which is used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Fórmula:C4H10ClNO2Forma y color:NeatPeso molecular:139.585-(PYRIDIN-4-YL)-2,3-DIAZABICYCLO[4.2.0]OCTA-1,5-DIEN-4-ONE
CAS:Pureza:95.0%Peso molecular:199.21299743652344(R)-Tamsulosin-d4 Hydrochloride
CAS:Producto controlado<p>Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)<br></p>Fórmula:C20H25D4ClN2O5SForma y color:NeatPeso molecular:449.0Methyl 4-Acetamido-5-bromo-2-methoxybenzoate
CAS:Producto controlado<p>Applications Methyl 4-Acetamido-5-bromo-2-methoxybenzoate is an impurity of bromopride (B686645), which is an antimetic.<br>References Fontaine, J., et al.: Arch. Int. Pharmacodyn. Ther., 213, 322 (1975), Lucker, P.W., et al.: Arzneim.-Forsch., 33, 453 (1983)<br></p>Fórmula:C11H12BrNO4Forma y color:Off-WhitePeso molecular:302.12Cloperastine Fendizoate
CAS:<p>Stability Hygroscopic<br>Applications Cloperastine fendizoate is used in the treatment of chronic non-productive cough. Antitussive. it is the salt of Cloperastine (CAS:3703-76-2)<br>References Aliprandi, P. et al.: Clin. Drug Invest. 22, 209 (2002)<br></p>Fórmula:C20H24ClNO·C20H14O4Forma y color:White To Off-WhitePeso molecular:648.19Roflumilast N-Oxide
CAS:Producto controlado<p>Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Fórmula:C17H14Cl2F2N2O4Forma y color:NeatPeso molecular:419.21Edoxaban-d6
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Edoxaban-d6 is the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C24H24D6ClN7O4SForma y color:Light Beige To Light BrownPeso molecular:554.09L-Lysine Clonixinate
CAS:<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Fórmula:C13H11ClN2O2·C6H14N2O2Forma y color:Off WhitePeso molecular:408.881-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole
CAS:<p>Impurity Aripiprazole Impurity 4<br>Applications 1-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl] Aripiprazole is a synthetic impurity of the drug aripiprazole (A771000). Aripiprazole is a novel atypical antipsychotic drug used in the treatment of schizophrenia. Aripiprazole Impurity 4<br>References Filijovic, N. D., et al.: Acta Chromatogr., 26, 13 (2014)<br></p>Fórmula:C36H42Cl2N4O4Forma y color:White To Off-WhitePeso molecular:665.649Captopril-d3
CAS:Producto controlado<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Fórmula:C9D3H12NO3SForma y color:White SolidPeso molecular:220.304-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide
CAS:Fórmula:C20H14F4N4O2SForma y color:NeatPeso molecular:450.417-Hydroxy Loxapine-D8
CAS:Producto controlado<p>Applications 7-Hydroxy Loxapine-D8 is a labelled analogue of 7-Hydroxy Loxapine (H943790).<br>References Kapur, S., et al.: Am. J. Psychiatry, 154, 1525 (1997); Rivers-Bulkeley, N. & Hollender, M.: Am. J. Psychiat., 139, 1345 (1982)<br></p>Fórmula:C18H10D8ClN3O2Forma y color:Dark YellowPeso molecular:351.86Tazarotene
CAS:<p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C21H21NO2SForma y color:Light YellowPeso molecular:351.46(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
CAS:Producto controlado<p>Applications (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);<br></p>Fórmula:C7H9ClN2OForma y color:NeatPeso molecular:172.61Levofloxacin-d8
CAS:Producto controlado<p>Applications Labelled S-(-)-Form of Ofloxacin. An antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Fórmula:C18H12D8FN3O4Forma y color:Light Yellow SolidPeso molecular:369.424-Hydroxy Phenobarbital-d5
CAS:Producto controladoFórmula:C122H5H7N2O4Forma y color:NeatPeso molecular:253.27Omeprazole-d3 Sulfide
CAS:Producto controladoFórmula:C172H3H16N3O2SForma y color:NeatPeso molecular:332.44Ethyl 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxylate
CAS:Pureza:95.0%Peso molecular:335.377990722656254-phenyl-2-hydrophthalazin-1-one, 98%
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:222.2469940185547Levosimendan Cyanoacetamide Hydrazone Impurity
CAS:Producto controlado<p>Applications Levosimendan Cyanoacetamide Hydrazone Impurity is an impurity of Levosimendan (L378000) which is a bioactive enantiomer of racemate, Simendan. It is a positive inotropic agent with vasodilating activity and also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Fórmula:C14H14N6O2Forma y color:Off-White To Dark OrangePeso molecular:298.3rac Phenylephrine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Phenylephrine is a selective α1-adrenergic receptor agonist used as a decongestant. Phenylephrine lowers intraocular pressure and is used as an agent to dilate the pupil.<br>References Lorenzetti, O.J. et al.: Exp. Eye Res., 12, 80 (1971); Ando, J. et al.: Nip. Yakur. Zas., 61, 471 (1965);<br></p>Fórmula:C9H14ClNO2Forma y color:NeatPeso molecular:203.676-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one
CAS:Pureza:98.0%Peso molecular:475.8500061035156Ref: 10-F549703
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