Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4949 productos de "Esteroides y derivados"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Producto controlado<p>Applications An impurity of Finasteride (F342000).<br></p>Fórmula:C21H31NO2Forma y color:NeatPeso molecular:329.48a-Epoxyabiraterone Acetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H33NO3Forma y color:NeatPeso molecular:407.55Atorvastatin-d5 tert-Butyl Ester
CAS:Producto controlado<p>Applications Atorvastatin-d5 tert-Butyl Ester is the labeled analogue of Atorvastatin tert-Butyl Ester (A791740), an impurity arising in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C37H38D5FN2O5Forma y color:NeatPeso molecular:619.7817α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Producto controlado<p>Applications Testosterone (T155000) derivative.<br></p>Fórmula:C27H36O2SForma y color:NeatPeso molecular:424.64Latanoprost Tris(triethylsilyl) Ether
CAS:Producto controlado<p>Impurity Latanoprost USP Related Compound D<br>Applications Latanoprost derivative. Latanoprost related compound D. Latanoprost USP Related Compound D.<br></p>Fórmula:C44H82O5Si3Forma y color:ColourlessPeso molecular:775.38Dexamethasone Acetate Impurity E
CAS:<p>Applications Dexamethasone Acetate Impurity E is a pregn-4-ene derivative used in the preparation of antiallergic and antiinflammatory drugs.<br>References Nedelec, L., et al.: Ger. Offen. (1978)<br></p>Fórmula:C24H33FO6Forma y color:NeatPeso molecular:436.51Prednicarbate
CAS:Producto controlado<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Fórmula:C27H36O8Forma y color:Off-WhitePeso molecular:488.57Dutasteride-13C6
CAS:Producto controlado<p>Applications Labelled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Fórmula:C2113C6H30F6N2O2Forma y color:NeatPeso molecular:534.49Tetrahydrocortisol 21-Acetate
CAS:Producto controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Forma y color:NeatPeso molecular:408.53(E/Z)-17-Deacetylnorgestimate
CAS:Producto controladoFórmula:C21H29NO2Forma y color:NeatPeso molecular:327.46Betamethasone 17-Propionate 21-Mesylate
CAS:<p>Impurity Clobetasol Propionate EP Impurity I<br>Stability Hygroscopic<br>Applications Betamethasone 17-Propionate 21-Mesylate (Clobetasol Propionate EP Impurity I) is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.<br>References Mitsukuchi, M. et al.: Chem. Pharm. Bull., 37, 3286 (1989);<br></p>Fórmula:C26H35FO8SForma y color:NeatPeso molecular:526.61Desisobutyryl Ciclesonide
CAS:Producto controlado<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Fórmula:C28H38O6Forma y color:White To Off-WhitePeso molecular:470.60(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Fórmula:C21H29NO2Forma y color:Off-WhitePeso molecular:327.46Testosterone Undecanoate-d21
CAS:Producto controladoFórmula:C30H27D21O3Forma y color:Off-WhitePeso molecular:477.84Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Fórmula:C22H32FO11PS•xNaForma y color:NeatPeso molecular:554.522298Betamethasone 21-Phosphate Biotin (>85%)
Producto controladoFórmula:C34H49FN3O10PSPureza:>85%Forma y color:NeatPeso molecular:741.8117-Hydroxypregn-5-ene-3,20-dione
CAS:Producto controlado<p>Applications 17-Hydroxypregn-5-ene-3,20-dione is used in the synthesis of physiologically active steroid esters and spirolactones that functions as potential aldosterone antagonists.<br>References Seletskii, B. M., et al.: Croat. Chem. Acta. , 58, 699 (1986)<br></p>Fórmula:C21H30O3Forma y color:NeatPeso molecular:330.463β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C21H30O2Forma y color:Single SolutionPeso molecular:314.46δ6-Gestodene
Producto controlado<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.419-Dehydroestrone
CAS:Producto controladoFórmula:C18H20O2Forma y color:White To Off-WhitePeso molecular:268.354'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Fórmula:C9H7F3N2O3Forma y color:NeatPeso molecular:248.16Testosterone (1 mg/mL in Acetonitrile)
CAS:Producto controladoFórmula:C19H28O2Forma y color:ColourlessPeso molecular:288.426-Deschloro Cyproterone Acetate
CAS:Producto controlado<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Fórmula:C24H30O4Forma y color:NeatPeso molecular:382.4933β,5α-Tetrahydrodeoxycorticosterone
CAS:<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Fórmula:C21H34O3Forma y color:White To Off-WhitePeso molecular:334.497-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Producto controlado<p>Applications Fulvestrant (F862500) impurity C.<br></p>Fórmula:C41H65F5O4S2Forma y color:NeatPeso molecular:781.07(11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Fórmula:C26H33BrO8Forma y color:NeatPeso molecular:553.44Boldione (1 mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C19H24O2Forma y color:Single SolutionPeso molecular:284.399-Chloro Triamcinolone Acetonide 21-Acetate
CAS:Producto controlado<p>Applications Triamcinolone Acetonide (T767165) impurity.<br></p>Fórmula:C26H33ClO7Forma y color:WhitePeso molecular:492.9896b-Hydroxylevonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Fórmula:C21H28O3Forma y color:White To Light YellowPeso molecular:328.452-Hydroxy Atorvastatin Lactone
CAS:Producto controlado<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Fórmula:C33H33FN2O5Forma y color:Off White SolidPeso molecular:556.62Fluocinolone Acetonide-13C3
CAS:Producto controladoFórmula:C2113C3H30F2O6Forma y color:NeatPeso molecular:455.47Epoxy Metradiene
CAS:Producto controlado<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.466-Keto Dexamethasone
Producto controlado<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Fórmula:C22H27FO6Forma y color:NeatPeso molecular:406.4417α-Hydroxyprogesterone Valerate
CAS:Producto controlado<p>Applications 17α-Hydroxy-progesterone Valerate acts as a synthetic Progesterone (P755900) reducing the chance of pre-term birth in women. Progesterone is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Fórmula:C26H38O4Forma y color:NeatPeso molecular:414.5825-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS:<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Fórmula:C40H65N3O4SForma y color:NeatPeso molecular:684.03a,a,a-Trifluorotoluene
CAS:Producto controlado<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Fórmula:C7H5F3Forma y color:ColourlessPeso molecular:146.117-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Producto controladoFórmula:C24H32O4S2Forma y color:NeatPeso molecular:448.6420-Hydroxydexamethasone
CAS:Producto controladoFórmula:C22H31FO5Forma y color:NeatPeso molecular:394.4815-Keto Latanoprost
CAS:<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Fórmula:C23H30O5Forma y color:NeatPeso molecular:386.486β-Hydroxymethylandrosta-1,4-diene-3,17-dione
CAS:Producto controladoFórmula:C20H26O3Forma y color:White To Off-WhitePeso molecular:314.42(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Producto controlado<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Fórmula:C25H32O6Forma y color:NeatPeso molecular:428.52Fluticasone-d3 17β-Carboxylic Acid
CAS:Producto controladoFórmula:C21H23D3F2O5Forma y color:NeatPeso molecular:399.44Testosterone-16,16,17-d3 3-Phenylpropionate
CAS:Producto controlado<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Fórmula:C28H33D3O3Forma y color:NeatPeso molecular:423.606β,17α-Dihydroxyprogesterone
CAS:Producto controladoFórmula:C21H30O4Forma y color:NeatPeso molecular:346.466-Oxo Boldione
CAS:Producto controlado<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Fórmula:C19H22O3Forma y color:Off-White To Light YellowPeso molecular:298.3823-Hydroxybudesonide
CAS:Producto controlado<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Fórmula:C25H34O7Forma y color:NeatPeso molecular:446.532-Hydroxy Estradiol 6-N3-Adenine
CAS:Producto controlado<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H27N5O3Forma y color:NeatPeso molecular:421.496α-Hydroxy Gestrinone Glucuronide
CAS:Producto controladoFórmula:C27H32O9Forma y color:Light YellowPeso molecular:500.54
![Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD289025.webp&w=3840&q=75)
![17α-Methyl-4-[(phenylthio)methyl]testosterone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM324800.webp&w=3840&q=75)
![7-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FP227275.webp&w=3840&q=75)
![(11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,2…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FB683236.webp&w=3840&q=75)
![(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FE890583.webp&w=3840&q=75)
