Péptidos y Proteínas
Los péptidos son cadenas cortas de aminoácidos unidas por enlaces peptídicos, mientras que las proteínas son cadenas más largas y complejas de aminoácidos que pueden adoptar estructuras tridimensionales funcionales. Ambos tipos de compuestos son esenciales para diversas funciones biológicas, como la catalización de reacciones (enzimas), la defensa inmunológica (anticuerpos) y la señalización celular. Las proteínas tienen una estructura jerárquica, que incluye la secuencia de aminoácidos, la estructura secundaria, terciaria y cuaternaria. Los péptidos se utilizan en terapias farmacológicas y cosméticas por sus propiedades biológicas específicas, como en el tratamiento de enfermedades metabólicas o la mejora de la regeneración celular. Las proteínas, por su parte, tienen aplicaciones en biotecnología, nutrición y medicina regenerativa.
En CymitQuimica ofrecemos péptidos y proteínas de alta pureza para investigación en biotecnología y aplicaciones terapéuticas.
Se han encontrado 3118 productos de "Péptidos y Proteínas"
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Lisinopril (S,S,R)-Diketopiperazine (~90%)
CAS:<p>Impurity Lisinopril EP Impurity D<br>Stability Hygroscopic<br>Applications Lisinopril (S,S,R)-Diketopiperazine (Lisinopril EP Impurity D) is an impurity of Lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor (1).<br>References 1. Goa, K. et al.: Drugs. 1996 Oct;52(4):564-88.<br></p>Fórmula:C21H29N3O4Pureza:~90%Forma y color:White To Off-WhitePeso molecular:387.47(±)-Methionine
CAS:<p>Applications (±)-Methionine is an essential amino acid involved in various biochemical processes in humans and mammals. Also in poultry meal as a source of nutrition.<br>References Martin-Venegas, R. et al.: Food Chem., 141, 1702 (2013); Austic, R. et al.: J. Agri. Food Chem., 61, 7341 (2013); Yan, L. et al.: J. Anim. Phys Anim Nutr., 97, 457 (2013);<br></p>Fórmula:C5H11NO2SForma y color:WhitePeso molecular:149.21TD-165
CAS:<p>TD-165, a PROTAC-based cereblon (CRBN) degrader, consists of a cereblon (CRBN) ligand-binding group, a linker, and a von Hippel-Landau (VHL) binding group[1].</p>Fórmula:C46H59N7O8SPureza:99.24%Forma y color:SolidPeso molecular:870.07Methionine
CAS:<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>Fórmula:C5H11NO2SPureza:99.13% - 99.62%Forma y color:SolidPeso molecular:149.21Cyclosporin AM 1 (>80%)
CAS:Producto controlado<p>Applications A cyclosporine metabolite specifically inhibits growth of renal cells in culture.<br>References Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991), Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (2006), Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).<br></p>Fórmula:C62H111N11O13Pureza:>80%Forma y color:NeatPeso molecular:1218.61Lopinavir
CAS:<p>Stability Hygroscopic<br>Applications A selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Fórmula:C37H48N4O5Forma y color:White SolidPeso molecular:628.80Bortezomib Trimer
CAS:Producto controlado<p>Applications Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C57H69B3N12O9Forma y color:NeatPeso molecular:1098.6663,3’,5-Triiodo-L-thyronine
CAS:Producto controladoFórmula:C15H12I3NO4Forma y color:White To Off-WhitePeso molecular:650.97N-2-(Hydroxyethyl)-L-valine-d4 (Technical grade)
CAS:Producto controlado<p>Applications Labelled N-2-(Hydroxyethyl)-L-valine (H942300). Cotinine and N-(2-hydroxyethyl)valine are markers of passive exposure to tobacco smoke in children.<br>References Dempsey, D., et al.: Clin. Pharmacol. Ther., 67, 458 (2000), Smith, C., et al.: Food Chem. Toxicol., 41, 807 (20030,<br></p>Fórmula:C7H11D4NO3Forma y color:WhitePeso molecular:165.22DL-Methionyl-DL-methionine
CAS:Producto controladoFórmula:C10H20N2O3S2Forma y color:NeatPeso molecular:280.4Cyclosporin H
CAS:<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C62H111N11O12Forma y color:NeatPeso molecular:1202.61[Des-Thr-ol8]-[D-Cys7]-Octreotide TFA
CAS:Producto controladoFórmula:C45H57N9O9S2•x(C2HF3O2)Forma y color:NeatPeso molecular:932.1211402Boceprevir (>90%)
CAS:Producto controladoFórmula:C27H45N5O5Pureza:>90%Forma y color:NeatPeso molecular:519.681,2-Bismethylphenidate (Mixture of Diastereomers)
Producto controlado<p>Applications 1,2-Bismethylphenidate is an impurity of methylphenidate (M325880), an CNS stimulant.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Fórmula:C23H27NO4Forma y color:NeatPeso molecular:381.46L-Methionine Sulfoxide
CAS:<p>Stability Temperature Sensitive, Hygroscopic<br>Applications An intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.<br>References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008), Balog, E., et al.: Biochem., 48, 3005 (2009),<br></p>Fórmula:C5H11NO3SForma y color:White To BeigePeso molecular:165.213,5,3',5'-Tetraiodo Thyroaldehyde
CAS:Producto controlado<p>Impurity Levothyroxine EP Impurity I; T4-Aldehyde (USP)<br>Applications 3,5,3',5'-Tetraiodo Thyroaldehyde (Levothyroxine EP Impurity I; T4-Aldehyde (USP)) is a Thyroid hormone analogue and a Thyroxine (T425600) analogue.<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Fórmula:C13H6I4O3Forma y color:Light Beige To BrownPeso molecular:717.80Tert-butyl Acetate
CAS:Producto controlado<p>Applications Tert-butyl Acetate is a common solvent used in the production of various industrial cleansers, thinners and adhesives and is also known as a VOC.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackay, D., et al.: SAR. QSAR. Enviro. Res., 23, 205 (2012); Yang, Y.S., et al.: Toxicol. Res., 26, 293 (2010);<br></p>Fórmula:C6H12O2Forma y color:ColourlessPeso molecular:116.16N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
CAS:<p>Applications Used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C15H15N3O3Forma y color:NeatPeso molecular:285.30Carfilzomib (2R,4S)-Diol
CAS:Producto controlado<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Forma y color:NeatPeso molecular:737.93Lopinavir Metabolite M-1
CAS:Producto controlado<p>Applications A major metabolite of Lopinavir (L469480) . It is a COVID19-related research product.<br>References Molla, A., et al.: J. Virology, 250, 255 (1998), Sham, H., et al.: Antimicrob. Agents Chemother., 42, 3218 (1998), Kumar, G., et al.: Drug Metab. Dispos., 27, 86 (1999),<br></p>Fórmula:C37H46N4O6Forma y color:NeatPeso molecular:642.78(S)-Tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetic Acid
CAS:Producto controladoFórmula:C9H16N2O3Forma y color:NeatPeso molecular:200.23Methyltetrazine-Amine
CAS:<p>Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.</p>Fórmula:C10H11N5Pureza:97.59%Forma y color:Pink SolidPeso molecular:201.23Dihydro Cyclosporin A
CAS:Producto controlado<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>Fórmula:C62H113N11O12Forma y color:WhitePeso molecular:1204.63N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:Producto controladoFórmula:C19H24N4O2Forma y color:White To Off-WhitePeso molecular:340.4195rhPTH (1-30) Trifluoroacetic Acid Salt Hydrate
Producto controlado<p>Impurity Teriparatide Impurity<br>Applications A fragment of human parathyroid hormone (hPTH) peptide sequence containing the 30 N-terminal residues of hPTH.<br>References Niall, et al.: Proc. Natl. Acad. Sci., 71, 384 (1974);<br></p>Fórmula:C157H260N48O46S2•x(C2HF3O2)•y(H2O)Forma y color:NeatPeso molecular:3620.1711402183,3',5'-Triiodo-L-thyronine
CAS:Fórmula:C15H12I3NO4Forma y color:Light Beige To GreyPeso molecular:650.97L-Valine-13C5,15N
CAS:Producto controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C5H1115NO2Forma y color:NeatPeso molecular:123.16-Perdeoxy-6-perchloro-γ-cyclodextrin, >90%
CAS:Fórmula:C48H72Cl8O32Pureza:>90%Forma y color:NeatPeso molecular:1444.69N,N-Dimethyl-4-hydroxymethoxy Clomiphene (~90%, contains ~10% Z-isomer)
CAS:Producto controladoFórmula:C25H26ClNO3Forma y color:NeatPeso molecular:423.93Bivalirudin Trifluoroacetic Acid Salt
CAS:<p>Applications Bivalirudin Trifluoroacetic Acid Salt is an anticoagulant drug that is a direct thrombin inhibitor. It is used for treatment of acute coronary syndromes, and is a safer alternative to heparin due to lower rates of bleeding as an adverse effect of anticoagulant in patients.<br>References Stone, G., et al.: N. Engl. J. Med, 355, 2203 (2006); Stone, G., et al.: N Engl J Med, 358, 2218 (2008);<br></p>Fórmula:C98H138N24O33·(C2HF3O2)xForma y color:NeatPeso molecular:2180.2911402(S)-Lisinopril-d5 Sodium
CAS:Producto controladoFórmula:C21H26D5N3NaO5Forma y color:NeatPeso molecular:433.513,5,3',5'-Tetraiodo Thyromandelic Acid (>85%)
CAS:Producto controlado<p>Impurity Levothyroxine T4-Hydroxyacetic Acid; T4-Hydroacetic Acid (USP)<br>Stability Hygroscopic<br>Applications 3,5,3',5'-Tetraiodo Thyromandelic Acid (Levothyroxine T4-Hydroxyacetic Acid; T4-Hydroacetic Acid (USP)) is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Fórmula:C14H8I4O5Pureza:>85%Forma y color:Light Orange Colour To BrownPeso molecular:763.83MK 677
CAS:<p>Applications MK-677 is a potent, non-peptide ghrelin receptor agonist.<br>References Kirstie, A., et al.: Mol. Pharmacol., 76, 802 (2009); Birgitte, H. et al.: Mol. Pharmacol., 75, 44 (2009)<br></p>Fórmula:C27H36N4O5S·CH4SO3Forma y color:NeatPeso molecular:624.80L-Thioproline
CAS:<p>Applications L-Thioproline is used to create a monolayer on gold electrodes for the determination Copper(II). L-Thioproline has shown to be an effect inhibitor of proline absorption in Saccharomyces chevalieri.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cui, X., et. al.: Sci. China Chem., 53, 257 (2010); Magana-Schwenchke, N., Schwencke, J.: BBA-Biomembranes, 173, 313 (1969)<br></p>Fórmula:C4H7NO2SForma y color:NeatPeso molecular:133.17Vasopressin Acetic Acid Salt
CAS:Producto controlado<p>Applications Vasopressin Acetic Acid Salt is an acidic salt of Vasopressin (V991530), an antidiurectic hormone.<br>References Tokushige, S., et al.: Internal Medicine, 55, 1199 (2016)<br></p>Fórmula:C46H65N15O12S2•(C2H4O2)Forma y color:NeatPeso molecular:1084.236005N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Fórmula:C16H24N2O4Forma y color:White To Light BeigePeso molecular:308.37L-Valine-d8
CAS:Producto controlado<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Fórmula:C52H8H3NO2Forma y color:NeatPeso molecular:125.20N-Glycylproline
CAS:<p>Applications N-Glycylproline was found to exhibit anti-ischemic effects on the metabolism of neuroactive amino acids and indices of energy turnover in the neocortex of rats after experimental brain ischemia.<br>References Bashun, Z.N., et al.: Neurochem. J., 7, 39 (2013);<br></p>Fórmula:C7H12N2O3Forma y color:NeatPeso molecular:172.182Thyroxine 4’-O-β-D-Glucuronide
CAS:<p>Applications Thyroxine 4-O-β-D-Glucuronide is a major metabolite and glucuronide conjugate of Thyroxine (T425600) formed via the glucuronidation of the phenyl hydroxyl group.<br>References Tong, Z. et al.: Drug Metab. Dispos., 35, 2203 (2007); West, C.D. et al.: J. Clin. INvest., 42, 1134 (1963);<br></p>Fórmula:C21H19I4NO10Forma y color:NeatPeso molecular:952.99L-Methionine-34S
CAS:<p>Applications Labelled L-Methionine, an essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.<br>References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),<br></p>Fórmula:C5H11NO234SForma y color:NeatPeso molecular:151.11Pidotimod
CAS:Producto controlado<p>Applications Immunostimulant used in patients with cell-mediated immunodepression.<br>References Gu, C., et al.: Pharm. Res., 25, 979 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Giagulli, C., et al.: Int. Immunopharmacol., 9, 1366 (2009),<br></p>Fórmula:C9H12N2O4SForma y color:NeatPeso molecular:244.27γ-Cyclodextrin
CAS:<p>Stability Hygroscopic<br>Applications γ-Cyclodextrin is used as nanomolecular encapsulation for drug delivery and pharmaceuticals. Used in the synthesis of unilamellar vesicles.<br>References Ikeda, A. et al.: Chem. Comm., 50, 1288 (2014); Gudmundsdottir, B. et al.: J. Ocular Pharm. Ther., 30, 35 (2014);<br></p>Fórmula:C48H80O40Forma y color:WhitePeso molecular:1297.12Lisinopril Cyclohexyl Analogue
CAS:Producto controlado<p>Impurity Lisinopril EP Impurity F<br>Applications Lisinopril Cyclohexyl Analogue (Lisinopril EP Impurity F) is a Lisinopril (L468985) impurity.<br>References Paraskevas, G., et al.: J. Pharm. Biomed. Anal., 29, 865 (2002),<br></p>Fórmula:C21H37N3O5Forma y color:NeatPeso molecular:411.54Perfluorophenol
CAS:Producto controlado<p>Applications Perfluorophenol is used in the synthesis of PGA-films as biodegradable polymers. It also participates in the synthesis of tripod macrocyclic Gd(III) chelates for cancer molecular MRI.<br>References Lee, K. et al.: Langmuir., 20, 2531 (2004); Zhou, Z. et al.: Biomater., 34, 7683 (2013);<br></p>Fórmula:C6HF5OForma y color:NeatPeso molecular:184.065-9-Leuprolide xTFA Salt
CAS:Producto controlado<p>Applications 5-9-Leuprolide is a metabolite of Leuprolide (L330590), a gonadotropin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors.<br>References Handelsman, David J., et al.: J. of Steroid Biochem. and Mol. Bio., 141, 113-120 (2014);Okada, Hiroaki, et al.: Pharma. Res., 8(6), 787-91 (1991)<br></p>Fórmula:C34H57N9O6·x(C2HF3O2)Forma y color:NeatPeso molecular:687.87+ x(114.02)3,5,3',5'-Tetraiodo Thyroacetamide
CAS:Producto controlado<p>Impurity Levothyroxine Acetamide Impurity<br>Applications 3,5,3',5'-Tetraiodo Thyroacetamide is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br>References Andre, M., et al.: J. Chromatogr., 741, 146 (1996),<br></p>Fórmula:C14H9I4NO3Forma y color:Light Orange Colour To Light BrownPeso molecular:746.84Eptifibatide
CAS:Producto controlado<p>Applications An arginine-glycine-aspartate-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events.<br>References Pathak, A., et al.: Cardiovas. Diabetol., 7 (2008), Hantgan, R., et al.: Biochem., 48, 8355 (2009), Giugliano, R., et al.: New Eng. J. Med., 360, 2176 (2009),<br></p>Fórmula:C35H49N11O9S2Forma y color:Off White SolidPeso molecular:831.963-Mercaptopropionic Acid
CAS:Producto controlado<p>Applications 3-Mercaptopropionic Acid (cas# 107-96-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C3H6O2SForma y color:NeatPeso molecular:106.14(S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid
CAS:Producto controlado<p>Applications (S)-2-((S)-4-Methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic Acid is an intermediate for Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C31H42N4O6Forma y color:NeatPeso molecular:566.69L-Carnitine-L-tartrate
CAS:Producto controlado<p>Applications L-Carnitine-L-tartrate (cas# 36687-82-8) is a useful research chemical.<br></p>Fórmula:C7H16NO3·C4H4O6Forma y color:White To Off-WhitePeso molecular:472.48Bortezomib-D8 (Major)
CAS:Producto controlado<p>Applications Labelled Bortezomib, which the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells.d6-3%d7-10%d8-86%<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)<br></p>Fórmula:C19H17D8BN4O4Forma y color:Off-WhitePeso molecular:392.29(2S,4S)-Sacubitril
CAS:<p>Stability Moisture Sensitive<br>Applications (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Forma y color:NeatPeso molecular:411.49(R)-Hydroxy Des(boric Acid) Bortezomib
CAS:Producto controlado<p>Impurity Bortezomib USP Impurity I<br>Applications (R)-Hydroxy Des(boric acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C. et al.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C19H24N4O3Forma y color:NeatPeso molecular:356.42N-des-succinyl-Sacubitril hydrochloride
CAS:Producto controlado<p>Applications (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.<br>References Liu, M., et al.: Faming Zhuanli Shenqing. CN 105168205 A 20151223. Dec 23, 2015; Wang, Z.: PCT Int. Appl. WO 2015154673 A1 20151015. Oct 15, 2015<br></p>Fórmula:C20H25NO2·HClForma y color:NeatPeso molecular:384.343,3’,5-Triiodo-D-thyronine
CAS:Producto controlado<p>Applications 3,3’,5-Triiodo-D-thyronine is a structural analogue o the thyroid homonef Thyroxine (T425600). 3,3’,5-Triiodo-D-thyronine has been shown to reduce cholesterol in blood serum.<br>References Mintz, D.O., et. al.: New Engl. J. Med., 266, 808 (1962)<br></p>Fórmula:C15H12I3NO4Forma y color:Off-White To Light BrownPeso molecular:650.97L-Threonine
CAS:Producto controlado<p>Applications L-enantiomer of Threonine. An essential amino acid for human development; last of the common amino acids to be discovered. Identified in oat protein.<br>References LeMaster, D.M., et al.: J. Biol. Chem., 257, 1224 (1982), Ballevre, O., et al.: Anal. Biochem., 193, 212 (1991), Roufs, J.B., et al.: Med. Hypotheses, 34, 20 (1991), Blin, O., et al.: J. Neurol., 239, 79 (1992),<br></p>Fórmula:C4H9NO3Forma y color:NeatPeso molecular:119.12Semaglutide Impurity 54 (D-Ala 18)
<p>D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molDes-Glu(3)-Semaglutide
<p>Des-Glu(3)-semaglutide is a semaglutide-related impurity. This des-amino acid form has got the glutamic acid or glutamate (Glu) amino acid from position 3 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.</p>Fórmula:C182H284N44O56Peso molecular:3,984.53 g/molD-Asp(9)-Semaglutide
<p>D-Asp(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the D-form of the amino acid D-aspartic acid (D-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molBortezomib intermediate I
CAS:<p>Bortezomib intermediate I is a metabolite of bortezomib, which is a research and development drug product. Bortezomib intermediate I is an impurity standard for bortezomib. Bortezomib intermediate I can be synthesized from the corresponding compound. It is an analytical standard used in pharmacopoeia and can be used as an API impurity or synthetic material in drug development. Bortezomib intermediate I has a high purity, natural origin, and a niche application. CAS No. 1248339-44-7</p>Fórmula:C25H36BN5O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:481.4 g/mol3,3',5,5'-Tetraiodothyroformic acid
CAS:<p>Cymit Quimicaetic beta-D-glucosiduronic acid</p>Fórmula:C13H6I4O4Pureza:Min. 95 Area-%Forma y color:Off-White PowderPeso molecular:733.8 g/molD-Ser(8)-Semaglutide
<p>D-Ser(8)-Semaglutide is a semaglutide impurity. The amino acid at position 8 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Ala-(19)-Semaglutide
<p>D-Ala(19)-Semaglutide is a semaglutide impurity. The amino acid at position 19 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Phe(6)-Semaglutide
<p>D-Phe(6)-Semaglutide is a semaglutide impurity. The amino acid at position 6 has been replaced by the D-form of the amino acid D-phenylalanine (D-Phe). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molLinear Semaglutide
<p>Linear semaglutide, or simply L-Sema, is the semaglutide compound without the lipid side chain modification. It is essentially a linear version of the peptide.</p>Fórmula:C152H230N42O47Peso molecular:3,397.76 g/molD-His(1)-Semaglutide
<p>D-His(1)-Semaglutide is a semaglutide impurity. The amino acid at position 1 has been replaced by the D-form of the amino acid D-histidine (D-His). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 60 (D-Arg 30)
<p>D-Arg(30)-Semaglutide is a semaglutide impurity. The amino acid at position 30 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/mol(S,E)-N-(1-(3-Methylbut-1-enylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
CAS:<p>R-N-(1-(3-methylbut-1-enyl)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide is a drug product that is used for the treatment of bacterial infections. The compound is an impurity in the synthesis of other compounds and is also used as an analytical standard. It is synthesized from commercially available starting materials and through custom synthesis. R-N-(1-(3-methylbut-1-enyl)-1--oxo--3--phenylpropan--2--yl)pyrazine--2--carboxamide has been shown to be metabolized by CYP450 enzymes, which are responsible for the metabolism of many drugs. R-(1-(3Methylbut 1Enylamino)-1Oxo 3Phenylpropan 2Yl)Pyrazine 2Carboxamide has not been evaluated as a drug product and therefore does not</p>Fórmula:C19H22N4O2Pureza:Min. 95%Peso molecular:338.4 g/molSemaglutide Impurity 29 (β-Asp-9)
<p>Beta-Asp-(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the beta-aspartic acid (also known as isoaspartic, isoAsp, β-Asp or beta-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 59
<p>D-Arg(28)-Semaglutide is a semaglutide impurity. The amino acid at position 28 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 51 (D-Thr 7)
<p>D-Thr(7)-Semaglutide is a semaglutide impurity. The amino acid at position 7 has been replaced by the D-form of the amino acid D-threonine (D-Thr). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 101 (D-Glu 3)
<p>D-Glu(3)-Semaglutide is a semaglutide impurity. The amino acid at position 3 has been replaced by the D-form of the amino acid D-glutamic acid (D-Glu). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Ser-(12)-Semaglutide
<p>D-Ser(12)-Semaglutide is a semaglutide impurity. The amino acid at position 12 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Val(10)-Semaglutide
<p>D-Val(10)-Semaglutide is a semaglutide impurity. The amino acid at position 10 has been replaced by the D-form of the amino acid D-valine (D-Val). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molSemaglutide Impurity 56 (D-Glu 21)
<p>D-Glu(21)-Semaglutide is a semaglutide impurity. The amino acid at position 21 has been replaced by the D-form of the amino acid D-glutamic acid (D-Glu). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molDes-His(1)-Semaglutide
<p>Des-His(1)-semaglutide is a semaglutide-related impurity. This des-amino acid form has the histidine (His) amino acid from position 1 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.</p>Fórmula:C181H284N42O58Peso molecular:3,976.5 g/molD-Thr(5)-Semaglutide
<p>D-Thr(5)-Semaglutide is a semaglutide impurity. The amino acid at position 5 has been replaced by the D-form of the amino acid D-threonine (D-Thr). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molLisinopril EP Impurity E
CAS:<p>Lisinopril EP Impurity E is an impurity of lisinopril, which is a prescription drug used to treat high blood pressure. This impurity was found in a preparative high performance liquid chromatography (HPLC) and mass spectroscopy analysis of the drug. The molecular weight of Lisinopril EP Impurity E was determined to be 317.2 amu, which corresponds to the molecular formula C7H13NO2. The FT-IR spectrum showed that this impurity has an ammonium group at 1859 cm-1 and butanoic acid at 1647 cm-1.</p>Fórmula:C21H31N3O5Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:405.49 g/molD-Ala(24)-Semaglutide
<p>D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/molD-Ser(11)-Semaglutide
<p>D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>Fórmula:C187H291N45O59Peso molecular:4,113.64 g/mol(R)-3-Methyl-1-(pyrazine- 2-carboxamido)butylboronic acid
<p>The compound is a drug product, analytical, and research material. The molecule has been synthesized and purified by the company's chemists. It is not an API impurity but an impurity standard for HPLC. This compound is a synthetic chemical that does not occur naturally in any living organism. It has been developed for use in drug development and research. The compound was custom synthesized by the company's chemists to meet customer demand for high purity standards of this compound. It is used as a pharmacopoeia standard for HPLC analysis and drug development.</p>Pureza:Min. 95%Lisinopril
CAS:<p>Lisinopril, an ACE inhibitor, treats hypertension, heart failure, heart attacks, and prevents diabetes-related eye and kidney issues.</p>Fórmula:C21H31N3O5Pureza:97.59% - 99.34%Forma y color:SolidPeso molecular:405.494-(Phenylamino)-1-benzyl-4-piperidinecarboxamide
CAS:Producto controlado<p>Applications Used as modulators of muscarinic receptors for treatment of CNS disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Coghlan, M., et al.: J. Med. Chem., 44, 1627 (2001), Ashcroft, F., et al.: J. Clin. Invest., 115, 2047 (2005), Bryan, J., et al.: Curr. Pharm. Des., 11, 2699 (2005),<br></p>Fórmula:C19H23N3OForma y color:NeatPeso molecular:309.41(1S,2S)-Bortezomib
CAS:Producto controlado<p>Impurity Bortezomib USP Impurity G<br>Stability Hygroscopic<br>Applications (1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hardy, J. et al.: Science, 297, 353 (2002); Paris, D. et al.: Mol. Med. 17, 149 (2011);<br></p>Fórmula:C19H25BN4O4Forma y color:NeatPeso molecular:384.24(2,6-Dimethylphenoxy)acetic Acid
CAS:Producto controladoFórmula:C10H12O3Forma y color:NeatPeso molecular:180.20(S)-(-)-α-Methylbenzylamine
CAS:Producto controlado<p>Applications (S)-(-)-α-Methylbenzylamine (cas# 2627-86-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8H11NForma y color:NeatPeso molecular:121.18Semaglutide impurity
CAS:<p>Lipid chain (stearic bi-acid) plus γ-glutamic acid or glutamate (γ-Glu) amino acid.</p>Fórmula:C35H63N3O13Peso molecular:733.89 g/molAlamethicin
CAS:<p>Alamethicin is isolated from Trichoderma viride. It is a channel-forming peptide antibiotic and induces voltage-gated conductance in model and cell membranes.</p>Fórmula:C92H150N22O25Pureza:98%Forma y color:SolidPeso molecular:1964.31CP5V
CAS:<p>CP5V, a PROTAC, degrades Cdc20, halts mitosis, and inhibits cancer growth by targeting it for VHL-mediated ubiquitination and proteasome destruction.</p>Fórmula:C46H66Cl3N9O12SPureza:98%Forma y color:SolidPeso molecular:1075.49(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide
Producto controladoFórmula:C19H22N4O4Forma y color:NeatPeso molecular:370.4(S)-Hydroxy Des(boric Acid) Bortezomib
CAS:Producto controlado<p>Impurity Bortezomib USP Impurity J<br>Applications (S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl, C. et al.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C19H24N4O3Forma y color:NeatPeso molecular:356.42Deschloro-4’-chloro Clomiphene Hydrochloride
CAS:Producto controlado<p>Applications An impurity of Clomiphene (C587025).<br></p>Fórmula:C26H29Cl2NOForma y color:NeatPeso molecular:442.429-(2,5-d|-Dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine Daptomycin
CAS:Producto controlado<p>Applications 9-(2,5-d|Dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine Daptomycin is a stereoisomer of Daptomycin (D193350), cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Fórmula:C72H99N17O25Forma y color:NeatPeso molecular:1602.66(alphaR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
CAS:Producto controlado<p>Applications Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.<br>References Kisselev, A., et al.: Chem. Biol., 8, 739 (2001), Kisselev, A., et al.: J. Biol. Chem., 278, 35869 (2003), Verdoes, M., et al.: Chem. Biol., 13, 1217 (2006),<br></p>Fórmula:C15H28BNO2·C2HF3O2Forma y color:NeatPeso molecular:379.22N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers)
CAS:Producto controlado<p>Applications N-(1-Carboxy-3-phenylpropyl)-S-lisinopril (Mixture of diastereomers) is an impurity of lisinopril (L468985), an orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Shinde, V., et. al.: J. Pharm. Biomed. Anal., 43, 381 (2007); Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)<br></p>Fórmula:C31H41N3O7Forma y color:NeatPeso molecular:567.675-Oxo-L-proline-d5
CAS:Producto controlado<p>Applications 5-Oxo-L-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Fórmula:C52H5H2NO3Forma y color:White To Off-WhitePeso molecular:134.14
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