Péptidos y Proteínas
Los péptidos son cadenas cortas de aminoácidos unidas por enlaces peptídicos, mientras que las proteínas son cadenas más largas y complejas de aminoácidos que pueden adoptar estructuras tridimensionales funcionales. Ambos tipos de compuestos son esenciales para diversas funciones biológicas, como la catalización de reacciones (enzimas), la defensa inmunológica (anticuerpos) y la señalización celular. Las proteínas tienen una estructura jerárquica, que incluye la secuencia de aminoácidos, la estructura secundaria, terciaria y cuaternaria. Los péptidos se utilizan en terapias farmacológicas y cosméticas por sus propiedades biológicas específicas, como en el tratamiento de enfermedades metabólicas o la mejora de la regeneración celular. Las proteínas, por su parte, tienen aplicaciones en biotecnología, nutrición y medicina regenerativa.
En CymitQuimica ofrecemos péptidos y proteínas de alta pureza para investigación en biotecnología y aplicaciones terapéuticas.
Se han encontrado 3118 productos de "Péptidos y Proteínas"
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THAL-SNS-032
CAS:<p>THAL-SNS-032 is a selective CDK9 degrader PROTAC.</p>Fórmula:C40H52N8O10S2Pureza:99.68%Forma y color:SolidPeso molecular:869.02Lanreotide Impurity 19 Ditrifluoroacetate (Kyn 4)
Fórmula:C53H69N11O11S2·2C2HF3O2Peso molecular:1100.32 2* 114.02Semaglutide Impurity 53 Tetratrifluoroacetate (D-ala 10)
Fórmula:C185H287N45O59·4C2HF3O2Peso molecular:4085.59 4*114.02Pasireotide Acetate
CAS:<p>The pKi of Pasireotide (SOM230) acetate for sst1, 2, 3, 4, and 5 were 8.2, 9.0, 9.1, less than 7.0, and 9.9, respectively.Cost-effective and quality-assured.</p>Fórmula:C60H70N10O11Pureza:98.64% - 99.92%Forma y color:SolidPeso molecular:1107.26Glucagon Impurity 10 Tetratrifluoroacetate Asp 28 Glucagon)
CAS:Fórmula:C153H224N42O50S·4C2HF3O2Peso molecular:3483.78 4*114.02L-Alanyl-L-glutamine
CAS:<p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>Fórmula:C8H15N3O4Pureza:99.71% - 99.97%Forma y color:SolidPeso molecular:217.22Leupeptin Hemisulfate
CAS:<p>Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities.</p>Fórmula:C20H38N6O4H2SO4Pureza:90% - ≥98%Forma y color:White SolidPeso molecular:475.59Liraglutide Impurity 25 Trifluoroacetate (11-D-Ser)
Fórmula:C172H265N43O51·C2HF3O2Peso molecular:3751.26 114.02Lanreotide Impurity 20 Ditrifluoroacetate (Dha 7)
Fórmula:C54H69N11O10S·2C2HF3O2Peso molecular:1064.27 2* 114.02(2S)-1-tert-Butyl 2-ethyl 5-hydroxypyrrolidine-1,2-dicarboxylate
CAS:Fórmula:C12H21NO5Peso molecular:259.30Semaglutide Impurity 107 Trifluororacetate(Des Glu 3)
Fórmula:C182H284N44O56·C2HF3O2Peso molecular:3984.53 114.02GRK5-IN-2
CAS:<p>GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor.</p>Fórmula:C20H20N4O4Pureza:99.92%Forma y color:SolidPeso molecular:380.41-Deoxynojirimycin hydrochloride
CAS:<p>1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves.</p>Fórmula:C6H14ClNO4Pureza:99.88%Forma y color:SolidPeso molecular:199.63Sacubitril hemicalcium salt
CAS:<p>Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM.</p>Fórmula:C48H56CaN2O10Pureza:99.86% - 99.93%Forma y color:SolidPeso molecular:861.06GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Forma y color:SolidPeso molecular:861.93Lanreotide Impurity 15 Ditrifluoroacetate (D-Tyr 3)
Fórmula:C54H69N11O10S2·2C2HF3O2Peso molecular:1096.33 2* 114.02L-Valine
CAS:<p>Essential branched-chain amino acid, stimulates muscle growth, aids tissue repair, precursor in penicillin synthesis.</p>Fórmula:C5H11NO2Pureza:98.96%Forma y color:White Solid CrystallinePeso molecular:117.15Calcitonin (Salmon) Impurity 45 Trifluoroacetate (Parallel Dimer)
Fórmula:C290H480N88O96S4·C2HF3O2Peso molecular:6863.79 114.02Calcitonin (Salmon) Impurity 46 Trifluoroacetate (Antiparallel Dimer)
Fórmula:C290H480N88O96S4·C2HF3O2Peso molecular:6863.79 114.02Icatibant Impurity 41 Trifluoroacetate (L-3-thienylalanine)
Fórmula:C59H89N19O13S·C2HF3O2Peso molecular:1304.54 114.02Ganirelix Impurity 18 Tritrifluoroacetate
Fórmula:C80H113ClN18O132C2HF3O2Peso molecular:1570.35 2*114.025-Oxo-DL-proline-d5
CAS:Producto controlado<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>Fórmula:C52H5H2NO3Forma y color:NeatPeso molecular:134.14Bortezomib
CAS:Producto controlado<p>Stability Hygroscopic and Moisture Sensitive<br>Applications Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);<br></p>Fórmula:C19H25BN4O4Forma y color:White To Off-WhitePeso molecular:384.24Dl-valine
CAS:Producto controlado<p>Applications Dl-valine<br></p>Fórmula:C5H11NO2Forma y color:NeatPeso molecular:117.15Oxytocin Acetate
CAS:<p>Applications Oxytocin Acetate is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.<br>References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),<br></p>Fórmula:C43H66N12O12S2·C2H4O2Forma y color:White To Off-WhitePeso molecular:1067.24Glucagon-d9 Trifluoroacetate
CAS:Producto controladoFórmula:C153H216D9N43O49Sx(C2HF3O2)Forma y color:NeatPeso molecular:3491.8Desisobutyl-n-butyl Bortezomib
CAS:<p>Impurity Bortezomib N-Pentyl Impurity<br>Applications Desisobutyl-n-butyl Bortezomib is an impurity of Bortezomib (B675700). Bortezomib impurity 5.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lin, G., et al.: J. Biol. Chem., 283, 34423 (2008);<br></p>Fórmula:C19H25BN4O4Forma y color:NeatPeso molecular:384.24(S)-Lisinopril Dimer
CAS:Producto controlado<p>Applications (S)-Lisinopril (L468985) impurity. Lisinopril Impurity G (Dimer Impurity)<br></p>Fórmula:C42H60N6O9Forma y color:WhitePeso molecular:792.96GSK1904529A
CAS:<p>GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .</p>Fórmula:C44H47F2N9O5SPureza:98.2% - 99.38%Forma y color:SolidPeso molecular:851.96(1R,2R)-Bortezomib
CAS:<p>Impurity Bortezomib USP Related Compound A<br>Applications (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Fórmula:C19H25BN4O4Pureza:>85%Forma y color:NeatPeso molecular:384.24Voclosporin-d4
CAS:Producto controlado<p>Applications Labelled Voclosporin (V678500). A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant.<br>References Aspeslet, L., et al.: Transplant Proc., 33, 1048 (2001), Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002), Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),<br></p>Fórmula:C63H107D4N11O12Forma y color:NeatPeso molecular:1218.65N-Acetyl-L-carnosine
CAS:Producto controlado<p>Applications Used in the treatment of cataracts and in the treatment of UV-induced immunosuppression. May act with with lipoic acid (L468725) to reverse age-related metabolic decline and also the indicies of oxidative stress.<br>References Babizhayev, M., et al.: J. Pharmacol. Toxicol., 1, 201 (2006), Min, J., et al.: J. Neurosci. Res., 86, 2984 (2008), Babizhayev, M., et al.: J. Drug Target., 17, 36 (2009); Hagen et. al, PNAS 99: 1870 (2002); Liu et. al, PNAS 99, 2356 (2002)<br></p>Fórmula:C11H16N4O4Forma y color:Off-WhitePeso molecular:268.27L-Methionine
CAS:<p>Applications Essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier.<br>References Benevenga, N.J., et al.: J. Agric. Food Chem., 22, 2 (1974), Fleisher, L.D., et al.: Clin. Endocrinol. Metab., 3, 37 (1974), Meinnel, T., et al.: Biochimie, 75, 1061 (1993),<br></p>Fórmula:C5H11NO2SForma y color:White To Off-WhitePeso molecular:149.21Desethyl Sacubitril-d4
CAS:Producto controladoFórmula:C22H21D4NO5Forma y color:NeatPeso molecular:387.464-(Phenylamino]-1-benzyl-4-piperidinecarboxylic Acid Methyl Ester
CAS:Producto controlado<p>Applications Remifentanil derivative.<br>References James, M.K., et al.: J. Pharmacol. Exp. Ther., 259, 712 (1991), Hoffman, W.E., et al.: Anesthesiology, 79, 107 (1993), Selinger, K., et al.: J. Pharm. Biomed. Anal., 12, 243 (1994), Richardson, T.D., et al.: Expert Opin. Drug Saf., 4, 643 (2005),<br></p>Fórmula:C20H24N2O2Forma y color:NeatPeso molecular:324.4168Oxytocin-d5 Trifluoroacetate
CAS:Producto controlado<p>Applications Labelled Oxytocin. The principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland.<br>References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),<br></p>Fórmula:C45H62D5F3N12O14S2Forma y color:White To Off-WhitePeso molecular:1126.24(2R,4R)-Sacubitril
CAS:<p>Applications (2R,4R)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Forma y color:NeatPeso molecular:411.491Carfilzomib (2S,4R)-Diol
Producto controlado<p>Applications Carfilzomib (2S,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Forma y color:NeatPeso molecular:737.93Carbetocin
CAS:<p>Applications An obstetric drug used to control postpartum hemorrhaging.<br>References Sanz-Nebot, V., et al.: Anal. Bioanal. Chem., 377, 306 (2003), Gimpl, G., et al.: Eur. J. Pharmacol., 510, 9 (2005), Handler, J., et al.: Theriogenol., 66, 1397 (2006), Klenerova, V., et al.: J. Physiol. Pharmacol., 60, 57 (2009),<br></p>Fórmula:C45H69N11O12SForma y color:NeatPeso molecular:988.16trans-4-Hydroxy-L-proline
CAS:Producto controlado<p>Applications A natural constituent of animal structural proteins such as collagen and elastin. Several microorganisms producing proline trans-4- and cis-3-hydroxylase were discovered and these enzymes were applied to the industrial production of trans-4- and cis-3-hydroxy-L-proline.<br>References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001);<br></p>Fórmula:C5H9NO3Forma y color:NeatPeso molecular:131.13N-Nitroso-D-proline
CAS:Producto controlado<p>Applications A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.<br>References Nagasawa, H.T., et al.: J. Med. Chem., 16 (5), 583-585 (1973)<br></p>Fórmula:C5H8N2O3Forma y color:NeatPeso molecular:144.13Protoporphyrin-9
CAS:<p>Stability Light Sensitive<br>Applications Protoporphyrin-9 is the precursor to heme sites and chlorophyll.<br></p>Fórmula:C34H34N4O4Forma y color:NeatPeso molecular:562.66Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5)
CAS:Producto controlado<p>Applications Teduglutide-d8 TFA salt x hydrate (Leu-methyl-d3+Phe-d5) is an isotopically labelled form of Teduglutide (T013795), which is glucagon-like peptide-2 (GLP-2) analogue that is used for the treatment of short bowel syndrome.<br>References Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br>Chemical Name: Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br></p>Fórmula:C164H244D8N44O55S•C2HF3O2•x(H2O)Forma y color:NeatPeso molecular:3760.0811402184-Methylbenzenesulfonic Acid Monohydrate
CAS:Producto controlado<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>Fórmula:C7H8O3S·H2OForma y color:WhitePeso molecular:190.22Carfilzomib
CAS:Producto controlado<p>Applications Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H57N5O7Forma y color:White To Off-WhitePeso molecular:719.91β-Hydroxy Thyroxine (>90%)
CAS:Producto controlado<p>Impurity Levothyroxine beta-Hydroxy Impurity / Levothyroxine beta-Hydroxy T4 Impurity<br>Applications It has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.<br>References Wawzone, S., et al.: J. Med. Chem., 6, 442 (1963),<br></p>Fórmula:C15H11I4NO5Pureza:>90%Forma y color:NeatPeso molecular:792.87Carfilzomib (2R,4R)-Diol
Producto controlado<p>Applications Carfilzomib (2R,4R)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Fórmula:C40H59N5O8Forma y color:NeatPeso molecular:737.93(2S,4R)-Sacubitril
CAS:Producto controlado<p>Stability Temperature Sensitive<br>Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H29NO5Forma y color:Colourless To Off-WhitePeso molecular:411.49N-Formyl Thyroxine
CAS:Producto controlado<p>Impurity Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)<br>Applications N-Formyl Thyroxine (Levothyroxine N-Formyl Impurity; N-Formyl-T4 (USP)) is a thyroxine derivative which showed less thyroid activity than Thyroxine Sodium (T425601).<br>References Basil, B., et al.: Br. J. Pharmacol. Chemother., 5, 315 (1950),<br></p>Fórmula:C16H11I4NO5Forma y color:NeatPeso molecular:804.88Teduglutide Trifluoroacetic Acid Salt
<p>Applications Teduglutide TFA Salt is a polypeptide consisting of 33 amino acids. It is glucagon-like peptide-2 (GLP-2) analogue that is used for the treatment of short bowel syndrome.<br>References Jeppesen, P., et al.: Gut, 54, 1224 (2005)<br></p>Fórmula:C164H252N44O55S•x(C2HF3O2)Forma y color:NeatPeso molecular:3752.13 + x(114.02)(1R,3S)-Camphoric Acid
CAS:<p>Applications (1R,3S)-Camphoric Acid is used primarily as a reagent in syntheses of crystalline structures. It is used in the preparation of polymeric transition metal dipyridylamine D-camphorate complexes.<br>References Blake, K. et al.: Crys. Growth Des., 12, 5215 (2012);<br></p>Fórmula:C10H16O4Forma y color:White SolidPeso molecular:200.23Thyroxine Methyl Ester
CAS:Producto controlado<p>Applications Thyroxine Methyl Ester is the methyl ester analog of Thyroxine (T425600) with high cross reactivity with thyroxine-specific monoclonal antibodies of humans and lab animals. It is an inhibitor of malate dehydrogenase.Thyroxine Methyl Ester is suitable for malate dehydrogenase (MDH) related research.<br>References Mpoko, C.N. et al.: Clin. Chim. Acta, 146, 215 (1985); Maggio, E.T. et al.: Biochim. Biophys. Acta Enzymol., 522, 284 (1978);<br></p>Fórmula:C16H13I4NO4Forma y color:NeatPeso molecular:790.90Romidepsin
CAS:Producto controlado<p>Applications Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.<br>References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),<br></p>Fórmula:C24H36N4O6S2Forma y color:White To Off-WhitePeso molecular:540.70Teduglutide
CAS:<p>Teduglutide (ALX-0600) is a glucagon-like peptide-2 analog that increases intestinal absorption and can be used in research on short bowel syndrome (SBS).</p>Fórmula:C164H252N44O55SPureza:98.08%Forma y color:SolidPeso molecular:3752.08Sacubitril Sodium Salt
CAS:Fórmula:C24H28NO5·NaForma y color:White To Off-WhitePeso molecular:433.473(R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium Chloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications (R)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride is an important co-factor of mammalian mitochondrial energy metabolism. It is also a good active ingredient for dry-skin.<br>References Geier, David A., et al.: Neurochem. Res., 38(11), 2336-2341 (2013);Tanno, Osamu, et al.: Fragrance J., 33(8), 82-85 (2005);<br></p>Fórmula:C7H16NO3·ClForma y color:White To Off-WhitePeso molecular:197.660Sugammadex Sodium-deuterated
CAS:Producto controlado<p>Applications Sugammadex Sodium-deuterated, is the labaled analogue of Sugammadex Sodium (S698100), which is the first in a class of drugs called selective relaxant binding agents that offers improved termination of the paralytic effects of neuromuscular blocking agents and may have many potential peri-operative benefits.<br>References Welliver, M., et al.: Drug Des. Devel. Ther., 2, 49 (2008);<br></p>Fórmula:C72H104Na8O48S8forundeuteratedForma y color:NeatPeso molecular:2178.006Sacubitril Calcium
CAS:<p>Applications Sacubitril is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014)<br></p>Fórmula:C24H28NOCa2Forma y color:NeatPeso molecular:430.522,5-Dioxopyrrolidine Sacubitril
CAS:<p>Applications Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C24H27NO4Forma y color:White To Off-WhitePeso molecular:393.48Thyroxine Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.<br>References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),<br></p>Fórmula:C15H10I4NO4·NaForma y color:NeatPeso molecular:798.85Lopinavir-d8
CAS:Producto controlado<p>Applications A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.<br>References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998), Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999), Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)<br></p>Fórmula:C37D8H40N4O5Forma y color:Light YellowPeso molecular:636.85Bivalirudin Plus-Gly Fragment Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C100H141N25O34•xC2HF3O2Forma y color:NeatPeso molecular:2237.34 + x(114.02)Cyclosporin B
CAS:<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C61H109N11O12Pureza:>80%Forma y color:NeatPeso molecular:1188.58Cyclosporin D
CAS:Producto controlado<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C63H113N11O12Forma y color:Off-WhitePeso molecular:1216.64Sacubitril-d4
CAS:Producto controlado<p>Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Fórmula:C242H4H25NO5Forma y color:Light YellowPeso molecular:415.521-Nitrosopyrrolidine-2-carboxylic Acid
CAS:Producto controlado<p>Applications 1-nitrosopyrrolidine-2-carboxylic acid (cas# 2571-28-0) is a useful research chemical.<br></p>Fórmula:C5H8N2O3Forma y color:NeatPeso molecular:144.129N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
CAS:<p>Impurity Bortezomib USP Impurity B<br>Applications N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.<br>References Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);<br></p>Fórmula:C14H14N4O2Forma y color:NeatPeso molecular:270.29(R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid
CAS:Producto controlado<p>Applications (R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.<br></p>Fórmula:C10H11NO2Forma y color:NeatPeso molecular:177.203,3',5,5'-Tetraiodo Thyroformic Acid (>90%)
CAS:<p>Impurity Levothyroxine EP Impurity H; T4-Benzoic Acid (USP)<br>Applications 3,3',5,5'-Tetraiodo Thyroformic Acid (Levothyroxine EP Impurity H; T4-Benzoic Acid (USP)) is a thyroid hormone analogue and a potent Thyroxine impurity.<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>Fórmula:C13H6I4O4Pureza:>90%Forma y color:White To Light BrownPeso molecular:733.80Liraglutide
CAS:Producto controladoFórmula:C172H265N43O51Forma y color:Off-WhitePeso molecular:3751.2Tabimorelin
CAS:Producto controlado<p>Applications NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4.<br>References Fabre, G., et al.: Biochem. Pharmacol., 37, 4389 (1988), Thummel, K., et al.: Clin. Pharmacol. Ther., 59, 491 (1996), Yu, D., et al.: J. Clin. Pharmacol., 39, 1203 (1999),<br></p>Fórmula:C32H40N4O3Forma y color:NeatPeso molecular:528.68N-Acetyl-L-methionine
CAS:Producto controlado<p>Applications N-Acetyl-L-methionine (CAS# 65-82-7) has been useful in the study of metabolic phenotypes of standard and cold-stored platelets.<br>References D’Alessandro, A., et al.: Transfusion (Malden, MA, US), 60, S96 (2020)<br></p>Fórmula:C7H13NO3SForma y color:NeatPeso molecular:191.00L-Prolinamide
CAS:<p>Applications Proline based organocatalyst.<br>References Alberg, D., et al.: Bioorg. Med. Chem. Lett., 19, 3888 (2009), Huang, X., et al.: J. Phys. Chem., 114, 1068 (2010),<br></p>Fórmula:C5H10N2OForma y color:White SolidPeso molecular:114.146N-Pyrazinylcarbonyl-L-phenylalanine
CAS:Producto controlado<p>Applications Used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Fórmula:C14H13N3O3Forma y color:WhitePeso molecular:271.27Cyclosporin C
CAS:Producto controlado<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Fórmula:C62H111N11O13Pureza:>80%Forma y color:NeatPeso molecular:1218.61Methyl Benzenesulfonate
CAS:Producto controlado<p>Applications A sulfonate ester as potential genotoxic impurity in drug substances. It may exert genotoxic effects in bacterial and mammalian cell systems.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eder, E., et al.: Xenobiotica, 12, 831 (1982), Li, W., et al.: J. Chromatogr., 1046, 297 (2004), Glowienke, S., et al.: Mutat. Res., 581, 23 (2005), Colon, I., et al.: J. Pharm. Biomed. Anal., 39, 477 (2005),<br></p>Fórmula:C7H8O3SForma y color:ColourlessPeso molecular:172.2Bestatin
CAS:<p>Bestatin (Ubenimex) competitively inhibits many aminopeptidases. Bestatin is a microbial metabolite and dipeptide with immunomodulatory and antitumor effects.</p>Fórmula:C16H24N2O4Pureza:98% - 99.63%Forma y color:White Crystalline PowderPeso molecular:308.37Daptomycin
CAS:<p>Applications Daptomycin is a Cyclic lipopeptide antibiotic derived from a fermentation product of Streptomyces roseosporus; disrupts plasma membrane function in gram-positive bacteria. Antibacterial.<br>References Allen, N.E., et al.: Antimicrob. Agents Chemother., 31, 1093 (1987), Tully, F.P., et al.: Expert Opin. Invest. Drugs, 8, 1223 (1999),<br></p>Fórmula:C72H101N17O26Forma y color:Light YellowPeso molecular:1620.67L-Methionine [R,S]-Sulfoximine
CAS:Producto controlado<p>Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.<br>References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)<br></p>Fórmula:C5H12N2O3SForma y color:NeatPeso molecular:180.23N-Acetyl-DL-methionine
CAS:Producto controlado<p>Applications C7H13NO3S (cas# 1115-47-5) is a useful research chemical.<br></p>Fórmula:C7H13NO3SForma y color:NeatPeso molecular:191.25(4R)-1-Methyl-4-propyl-L-proline Hydrochloride
CAS:Producto controlado<p>Applications Proline derivative, and an intermediate in the production of biosynthetic antibiotics.<br></p>Fórmula:C9H17NO2·ClHForma y color:NeatPeso molecular:207.70(R)-Lisinopril Sodium Salt
CAS:<p>Applications R,S,S-Isomer of Lisinopril (L468985).<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)<br></p>Fórmula:C21H31N3NaO5Forma y color:NeatPeso molecular:428.483,3’,5-Triiodo-L-thyronine 4’-O-Sulfate
CAS:<p>Applications 3,3’,5-Triiodo-L-thyronine 4’-O-Sulfate is the sulfoconjugated metabolite of 3,3’,5-Triiodo-L-thyronine (T795380).<br>References Rooda, S.J. et al.: J. Clin. Endocrinol. Metab., 69, 552 (1989); Everts, M. E. et al.: Metab. Clin. Exp., 43, 1282 (1994); Pinna, G. et al.: Endocrinology, 143, 1789 (2002);<br></p>Fórmula:C15H12I3NO7SForma y color:NeatPeso molecular:731.0413C6-Lys Octreotide Trifluoroacetate
CAS:Producto controladoFórmula:C4313C6H66N10O10S2•xC2HF3O2Forma y color:White To Off-WhitePeso molecular:1025.2011402Glecaprevir
CAS:Producto controlado<p>Applications Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.<br>References Kwo, P., et. al.: J. Hepatol, 67, 263 (2017)Gane, E., et. al.: N. Engl. J. Med, 377, 1448 (2017)<br></p>Fórmula:C38H46F4N6O9SForma y color:NeatPeso molecular:838.86
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