Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2587 productos de "Sulfonamidas y derivados"
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Nafamostat Mesylate
CAS:<p>Applications A non-peptide proteaseinhibitor.<br>References Ayoyama, T., et al.: Chem. Pharm. Bull., 33, 1458 (1985)<br></p>Fórmula:C19H17N5O2·2CH4O3SForma y color:NeatPeso molecular:539.58Sulfadiazine-13C6
CAS:<p>Applications The isotopically labelled drug Sulfadiazine. Antibacterial.<br>References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),<br></p>Fórmula:C6C4H10N4O2SForma y color:Off-WhitePeso molecular:256.23rac Bendroflumethiazide-d5
CAS:Producto controladoFórmula:C15H9D5F3N3O4S2Forma y color:NeatPeso molecular:426.453-Ethyl-2,5-dihydro-4-methyl-2-oxo-N-(2-phenylethyl)-1H-pyrrole-1-carboxamide
CAS:Producto controlado<p>Applications Intermediate for the preparation of Glimepiride.<br></p>Fórmula:C16H20N2O2Forma y color:NeatPeso molecular:272.344-Acetamidophenyl β-D-Glucuronide Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 4-Acetamidophenyl β-D-Glucuronide is a major urinary metabolite of Acetaminophen (A161220) (Paracetamol) in human (1). Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis (2,3).<br>References (1) Johnston, D., et al.: J. Chem. Res., Synop., 12, 406 (1988)(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C14H16NO8·NaForma y color:White To Light RedPeso molecular:349.272-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone
CAS:Producto controlado<p>Applications Degradation product/impurity of trimethoprim (T795615).<br>References Roth, B., et al.: J., Med. Pharm. Chem., 5, 1103 (1962), Bergh, J., et al.: J. Pharm. Sci., 78, 348 (1989),<br></p>Fórmula:C14H17N3O4Forma y color:NeatPeso molecular:291.30rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen Impurity K)
CAS:<p>Impurity Ibuprofen EP Impurity K<br>Applications rac 2-(4-Formylphenyl)propionic Acid (Ibuprofen EP Impurity K) is a degradation product of Ibuprofen arising from oxidative and thermal treatments. Ibuprofen impurity K.<br>References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Vargas, F., et al.: Pharmazie, 11, 767 (1991), Lee, J., et al.: Pharm. Res., 9, S170 (1995),<br></p>Fórmula:C10H10O3Forma y color:White To Light YellowPeso molecular:178.181-Propyl Etodolac
CAS:Producto controlado<p>Impurity Etodolac EP Impurity G<br>Applications 1-Propyl Etodolac (Etodolac EP Impurity G) is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/β-catenin inhibitors, or anti-inflammatory agent.<br>References Robinson, W. et al.: J. Pharm. Exp. Ther., 203, 729 (1977); Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Fórmula:C18H23NO3Forma y color:NeatPeso molecular:301.38(R)-(-)-Etodolac
CAS:Producto controlado<p>Applications The R-enantiomer of Etodolac (E933090). Anti-inflammatory; analgesic.<br>References Boxenbaum, H., et al.: J. Pharmacokin. Biopharm., 10, 201 (1982), Iwatsubo, T., et al.: Biopharm. Drug Dispos., 17, 273 (1996), Obach, R., et al.: J. Pharmacol. Exp. Ther., 283, 46 (1997),<br></p>Fórmula:C17H21NO3Forma y color:NeatPeso molecular:287.3544-Chloro-3-sulfamoylbenzoic Acid
CAS:Producto controladoFórmula:C7H6ClNO4SForma y color:NeatPeso molecular:235.64Phenacetin-d3
CAS:Producto controlado<p>Applications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)<br></p>Fórmula:C10H10D3NO2Forma y color:NeatPeso molecular:182.234-Demethyltrimethoprim
CAS:<p>Applications 4-Demethyltrimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent.<br>References Mengelers, M.J.B., et al.: J. Vetern. Pharmacol. Therap., 20, 24 (1997); Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Fórmula:C13H16N4O3Forma y color:NeatPeso molecular:276.29Saccharin Sodium Salt Dihydrate
CAS:Fórmula:C7H4NO3S·Na·2H2OForma y color:White Crystalline PowderPeso molecular:241.20Mesosulfuron-methyl
CAS:<p>Stability Unstable in Solution<br>Applications Mesosulfuron-methyl can be used in biological study of targeted screening and safety evaluation of 276 agrochemical residues in raisins using buffered ethyl acetate extraction and liquid chromatography-tandem mass spectrometry analysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shabeer, T. P. A., et al.: Chemosphere, 184, 1036 (2017)<br></p>Fórmula:C17H21N5O9S2Forma y color:NeatPeso molecular:503.512-Amino-4-chloro-5-sulfamoyl-o-benzotoluidide
CAS:Producto controlado<p>Applications 2-Amino-4-chloro-5-sulfamoyl-o-benzotoluidide is an intermediate in the synthesis of Metolazone (M338750); a diuretic and antihypertensive agent.<br>References Curry, C.L., et al.: Clin. Ther., 9, 47 (1986); Kiyingi, A., et al.: Lancet, 335, 29 (1990); Chen, G., et al.: Shenyang Yaoke Daxue Xuebao, 21, 109 (2004)<br></p>Fórmula:C14H14ClN3O3SForma y color:NeatPeso molecular:339.82-Acetamido-5-mercapto-1,3,4-thiadiazole
CAS:Producto controlado<p>Impurity Acetazolamide EP Impurity C<br>Applications Acetazolamide intermediate. Acetazolamide EP Impurity C<br>References Almajan, G., et al.: Bioorg. Med. Chem. Lett., 15, 2347 (2005), Talath, S., et al.: Eur. J. Med. Chem., 41, 918 (2006), Srinivasu, P., et al.: J. Pharm. Biomed. Anal., 52, 142 (2010),<br></p>Fórmula:C4H5N3OS2Forma y color:NeatPeso molecular:175.23Dapsone Hydroxylamine-d4
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications A labelled metabolite of Dapsone.<br>References Preuss, C.V., et al.: Biochem. Pharmacol., 51, 1661 (1996),<br></p>Fórmula:C12H8D4N2O3SForma y color:NeatPeso molecular:268.324,4’-Dichlorodiphenyl Sulfone
CAS:Producto controlado<p>Applications 4,4’-Dichlorodiphenyl Sulfone is an impurity of Dapson (D193250), an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Carlsson, L., et al.: J. Chem. Info. Model., 49, 2551 (2009); Chan, T.S., et al.: Toxicol. App. Pharmacol., 232, 456 (2008);<br></p>Fórmula:C12H8Cl2O2SForma y color:Off-WhitePeso molecular:287.161,2-Benzisoxazole-3-methanesulfonate Sodium Salt
CAS:Producto controladoFórmula:C8H6NO4S·NaForma y color:NeatPeso molecular:235.19Mesotrione
CAS:<p>Applications Mesotrione is a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deng, L., et al.: Indus. Crops. Prod., 39, 154 (2012); Pileggi, M., et al.: Chemosphere., 86, 1127 (2012); McElroy, J., S., Hort. Technol.,22, 627 (2012);<br></p>Fórmula:C14H13NO7SForma y color:Light YellowPeso molecular:339.32N2-Methyl Trimethoprim (Impurity)
CAS:Producto controlado<p>Applications N2-Methyl Trimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections.<br>References Dauber-Osguthorpe, P., et al.: Proteins, 4, 31, (1988); Darrell, J., et al.: J. Clin. Pathol., 21, 202 (1968); Zhanel, G., et al.: Antimicrob. Agents Ch., 44, 1089 (2000)<br></p>Fórmula:C15H20N4O3Forma y color:NeatPeso molecular:304.34Zonisamide-d4
CAS:Producto controlado<p>Applications Labelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.<br>References Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),<br></p>Fórmula:C82H4H4N2O3SForma y color:Light Brown SolidPeso molecular:216.25Nimesulide
CAS:<p>Applications Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Fórmula:C13H12N2O5SForma y color:Light YellowPeso molecular:308.31rac Bendroflumethiazide
CAS:Producto controladoFórmula:C15H14F3N3O4S2Forma y color:WhitePeso molecular:421.41Dapsone-d4
CAS:Producto controlado<p>Applications A labelled antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C12H8D4N2O2SForma y color:NeatPeso molecular:252.332-Methylindole
CAS:Producto controlado<p>Applications 2-Methylindole is an intermediate in the synthesis of indole derivative with potential antifungal activities.<br>References Rodriguez, S., et al.: Natural. Prod. Res., 22, 253 (2008); Zhang, B.G., et al.: Bioresource., 100, 5687 (2009);<br></p>Fórmula:C9H9NForma y color:NeatPeso molecular:131.1745Hydrochlorothiazide
CAS:Fórmula:C7H8ClN3O4S2Forma y color:White Crystalline PowderPeso molecular:297.74N-(Methylsulfonyl)-4-(desnitro) Nimesulide
CAS:<p>Impurity Nimesulide EP Impurity E<br>Applications N-(Methylsulfonyl)-4-(desnitro) Nimesulide is an impurity of Nimesulide (N477500).<br>References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),<br></p>Fórmula:C14H15NO5S2Forma y color:NeatPeso molecular:341.40N-(p-Chlorobenzoyl)-p-anisidine
CAS:Producto controlado<p>Applications N-(p-Chlorobenzoyl)-p-anisidine is a COX-1 inhibitor analgesics that do not cause gastric damage.<br>References Kakuta, H., et al.: J. Med. Chem., 51, 2400 (2008);<br></p>Fórmula:C14H12ClNO2Forma y color:White To Off-WhitePeso molecular:261.7Ibuprofen Lysinate
CAS:Producto controlado<p>Applications Ibuprofen Lysinate is used in the treatment of hemodynamically significant patent ductus arteriosus in neonates greater than 27 week gestational age.<br>References Pai, V.B., et. al.: Pharmacotherapy, 28, 1162 (2008)<br></p>Fórmula:C13H18O2·C6H14N2O2Forma y color:YellowPeso molecular:352.468N-(2-Pyridyl)oxamic Acid
CAS:Producto controlado<p>Applications A metabolite of Tenoxicam (T019500). A degradation product and pathway of Lornoxicam.<br>References Tsuchiya, S., et al.: Cancer Res., 42, 1530 (1982), Talanian, R., et al.: J. Med. Chem., 43, 3351 (2000), Fuentes-Prior, P., et al.: Biochem. J., 384, 201 (2004), Han, Y., et al.: Bioorg. Med. Chem. Lett., 15, 1173 (2005),<br></p>Fórmula:C7H6N2O3Forma y color:WhitePeso molecular:166.132’-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 2’-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine Hydrochloride is an impurity of Sulfasalzine (S699084).<br></p>Fórmula:C29H22N6O7S2•xHClPureza:>85%Forma y color:NeatPeso molecular:630.65 + x(36.46)rac 2-Hydroxy Ibuprofen
CAS:Producto controlado<p>Applications A human metabolite of Ibuprofen.<br>References Bales, J., et al.: Clin. Chem., 31, 757 (1985), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Zwiener, C., et al.: Anal. Bioanal. Chem., 372, 569 ( 2002), de Bernardi, B., et al.: J. Clin. Oncol., 21, 1592 (2003),<br></p>Fórmula:C13H18O3Forma y color:Off-WhitePeso molecular:222.284,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene
<p>Stability Light Sensitive<br>Applications 4,4'-Bis(4-aminobenzenesulfonyl)hydrazobenzene is a dimer impurity of Dapsone (D193250); an antibacterial used in the treatment of dermatitis herpetiformis.<br>References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950); Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009); Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009); Varma, M., et al.: J. Med. Chem., 52, 4844 (2009)<br></p>Fórmula:C24H22N4O4S2Forma y color:Off WhitePeso molecular:494.59Brinzolamide Hydrochloride
CAS:Producto controlado<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Fórmula:C12H21N3O5S3·ClHForma y color:NeatPeso molecular:419.97Isosulfamethoxazole
CAS:<p>Applications Isosulfamethoxazole is an impurity of the antibacterial drug Sulfamethoxazole (S699086). It is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 467 (1973), Wormser, G.P., et al.: Drugs, 24, 459 (1982), Wharton, M., et al.: Ann. Intern. Med., 105, 37 (1986),<br></p>Fórmula:C10H11N3O3SForma y color:NeatPeso molecular:253.28Methazolamide
CAS:Producto controlado<p>Applications Methazolamide is a carbonic anhydrase inhibitor. Methazolamide is used in the treatment of glaucoma.<br>References Iyer, G.R. et al.: J. Pharmac. Biomed. Anal., 16, 1021 (1998); Maren, T. H. et al.: Invest. Ophthamol. Vis. Sci., 16, 730 (1977);<br></p>Fórmula:C5H8N4O3S2Forma y color:NeatPeso molecular:236.277-Ethyltryptophol
CAS:<p>Impurity Etodolac EP Impurity H<br>Applications 7-Ethyltryptophol (Etodolac EP Impurity H) is a key intermediate in the preparation of the non-steroidal anti-inflammatory drug Etodolac.<br>References El Kousy, N., et al.: J. Pharm. Biomed. Anal., 20, 185 (1999),<br></p>Fórmula:C12H15NOForma y color:WhitePeso molecular:189.25Tolnaftate
CAS:Producto controlado<p>Applications Antifungal.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C19H17NOSForma y color:NeatPeso molecular:307.41Sulfachloropyridazine
CAS:<p>Applications Sulfachloropyridazine is an antibacterial compound.This compound is a contaminant of emerging concern (CECs).<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Fórmula:C10H9ClN4O2SForma y color:WhitePeso molecular:284.72Cantrodifene
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications 4-Isothiocyanato-4'-nitrodiphenyl ether (cas# 19881-18-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C13H8N2O3SForma y color:NeatPeso molecular:272.27N-Acetyl Sulfadiazine-d4 (Major)
CAS:Producto controlado<p>Applications A major labelled metabolite of Sulfadiazine.<br>References Woolley, J., et al.: Drug Metab. Dispos., 7, 94 (1979), Nielsen, P., et al.: Biochem. Pharmacol., 35, 2509 (1986), Anari, M., et al.: Anal. Chem., 76, 823 (2004), Edlund, P., et al.: J. Pharm. Biomed. Anal., 34, 1079 (2004),<br></p>Fórmula:C12H8D4N4O3SForma y color:NeatPeso molecular:296.345-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid Potassium Salt
CAS:Producto controlado<p>Impurity Acetazolamide EP Impurity E<br>Applications 5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonic Acid is an impurity of Acetazolamide (A161500). (Acetazolamide EP impurity E)<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H4KN3O4S2Forma y color:NeatPeso molecular:261.32p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Fórmula:C11H14O2Forma y color:WhitePeso molecular:178.233-(4-Isobutylphenyl)propanoic Acid
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity F<br>Applications 3-(4-Isobutylphenyl)propanoic acid (Ibuprofen EP Impurity F) is an impurity of Ibuprofen (I140000). Ibuprofen impurity F as per EP.<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Zhao, J., et al.: Anal. Chem., 72, 302 (2000), Kucera, R., et al.: J. Pharm. Biomed. Anal., 38, 609 (2005),<br></p>Fórmula:C13H18O2Forma y color:NeatPeso molecular:206.285-Oxomefruside
CAS:<p>Applications 5-Oxomefruside is a lactone metabolite and impurity of the drug Mefruside (M205150).<br>References Puetter, J., et al.: Biochimica et Biophysica Acta, General Subjects, 286, 186 (1972).<br></p>Fórmula:C13H17ClN2O6S2Forma y color:NeatPeso molecular:396.87Bumetanide 3-(Butyl(nitroso)amino)
CAS:Producto controlado<p>Impurity Bumetanide Impurity<br>Applications Bumetanide 3-(Butyl(nitroso)amino) is an impurity of Bumetanide(B689550). Bumetanide is a diuretic.<br>References Ward, A., et al.: Drugs, 28, 426 (1984), Gradeen, C.Y, et al.: J. Anal. Toxicol., 14, 123 (1990), Tata, P.N.V., et al.: Anal. Profiles Drug Subs. Excip., 22, 107 (1993),<br></p>Fórmula:C17H19N3O6SForma y color:NeatPeso molecular:393.41
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