Aminoácidos (AA)

<p>Applications 2-[(4-methoxyphenoxy)methyl]benzoic Acid is an intermediate used in synthesis of (E)-2-Hydroxy Doxepin (H941785), which is a metabolite of Doxepin (D550000).<br>References Pinder, R., et al.: Drugs, 13, 161 (1977), Ghabrial, H., et al.: Drug Metab. Dispos., 19, 596 (1991), Midha, K., et al.: Eur. J. Clin. Pharmacol., 42, 539 (1992),<br></p>

<p>Applications Cyclopropyl-2,2,3,3-d4-methyl-d2 Alcohol (CAS# 1219805-67-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 (CAS# 1426174-46-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Amino-4-methyl-pyridazine is a reactant used in the synthesis of antiinflammatory agents such as 2-​phenylimidazo[1,​2-​b]​pyridazine-​3-​acetic acid.<br>References Sacchi, A. et al.: Eur. J. Med. Chem., 34, 1003 (1999);<br></p>

<p>Applications N-Boc-4-aminophenethylamine is used in the preparation of N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptors.<br>References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012)<br></p>

<p>Applications Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.<br>References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);<br></p>

<p>Applications 2-methylpentane-1,3-diol (cas# 149-31-5) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Amino-5-methylthiophene-3-carboxylate is used as a starting reagent in the synthesis of Thieno[2,3-b]Pyridinones and 4-Hydroxy-6-oxo-6,7-dihydro-thieno[2,3-b]pyridine derivatives, compounds that act as cytoprotectants and inhibitors of the N-Methyl-D-aspartate (NMDA) receptor.<br>References Buchstaller, H., et al.: J. Med. Chem., 49, 864 (2006); Hwang, K., et al.: Arch. Pharm. Res., 24, 270 (2001)<br></p>

<p>Applications (2S)-2-Hydroxy-2-methylbutanoic Acid is a useful building block for organic synthesis.<br></p>

<p>Applications 2'-OMe-Ac-C Phosphoramidite (CAS# 199593-09-4) is a nucleotide used in the solid-phase synthesis of phosphorothioate oligonucleotides using sulfurization byproducts for in situ capping.<br>References Yang, J.; et al.: J. Org. Chem., 83, 11577 (2018);<br></p>

<p>Applications 2-Methoxytoluene-alpha,alpha,alpha-d3 (CAS# 258832-47-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Bromo-1-(2,2-difluoro-1-methylcyclopropyl)ethanone is used in the preparation of triazole fungicides.<br>References Gassen, K.R., et al.: Eur. Pat. Appl. (1990);<br></p>

<p>Applications 1-Chloro-3-methoxy-2-propanol is used in the synthesis of O-Methylganciclovir (M275440), an analogue of Ganciclovir (G235000) and displays excellent antiviral activity when tested in vivo against herpes simplex virus type 1 infection in mice.<br>References Winkelmann, E., et. al.: Arzneimittel-Forsch, 38, 1545 (1988)<br></p>

<p>Applications 2-(4-Boc-piperazino)pyrimidine-5-boronic acid pinacol ester<br></p>