Aminoácidos (AA)

<p>Applications Used in the synthesis of novel amphiphilic spin probes with the paramagnetic Doxyl group in the polar region.<br>References Chignell, C., et al.: Spin Labeling, 2, 223 (1979), Strancar, J., et al.: J. Membr. Biol.,193, 15 (2003), Ilas, J., et al.: J. Med. Chem., 48, 2108 (2005),<br></p>

<p>Applications N-Boc-4-phenyl-L-phenylalanine is a reactant used in the synthesis of novel phenylalanines derived diamides as factor XIa inhibitors used in the treatment.<br>References Smith, L. et al.: Bioorg. Med. Chem. Lett., 26, 472 (2016);<br></p>

<p>Applications 6-Amino-1-methyluracil is known to exert inhibitory effects towards DNA repair glycosylase. It is also known to be used as a flame retardant.<br>References Speina, E., et al.: Acta. Bioch. Polonica., 52, 167 (2005);<br></p>

<p>Applications 4,4'-Dihydroxy-trans-α-methylstilbene-d3 is labelled 4,4'-Dihydroxy-trans-α-methylstilbene which is an intermediate used to synthesize thermotropic liquid crystalline polymers.<br>References Rameshbabau, K., et al.: Liquid Crystals, 31, 843 (2004); Percec, V., et al.: Polymer Preprints, 30, 444 (1989); De Backer, C., et al.: Macromol. Chem. Phys., 196, 1495 (1995)<br></p>

<p>Applications 1-Bromo-4-fluoro-2-methyl-5-nitrobenzene<br></p>

<p>Applications 5-Bromo-2-(N-methylamino)pyridine is useful for the synthetic preparation of halo aminopyridines.<br>References Sun, C., et al.: ACS Omega, 4, 10534 (2019)<br></p>

<p>Applications N-[[4-[2-[(5-Chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester is an impurity in the synthesis of Gyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic.<br>References Mizukami, et al.: Arzneimittel-Forsch., 19, 1413 (1969); Efendic, S., et al.: Proc. Nat. Acad. Sci. USA, 76, 5901 (1979); Feldman, J.M.: Pharmacotherapry, 5, 43 (1985);<br></p>

<p>Applications 1,3-Bis[2,6-bis(1-methylethyl)phenyl]-2-carboxy-1H-imidazolium Inner Salt is synthesized from 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride(B426650). 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is used as a reagent in the synthesis of NHC Copper(I) complexes bearing dipyridylamine ligands which exhibit interesting luminescent properties and are potential candidates for organic light-emitting diode applications. 1,3-Bis(2,6-diisopropylphenyl)imidazolium Chloride is also used as a reagent in the synthesis of 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic Acid Methyl Ester (D476595); the methyl ester derivative of the drug Vadimezan (V084950).<br>References Marion, R., et al.: Inorg. Chem., 53, 9181 (2014); Buchanan, C.M., et al.: Clin. Sci., 122, 449 (2012); Fruh, M., et al.: Clin. Lung. Cancer., 14, 34 (2013)<br></p>

<p>Stability Moisture Sensitive<br>Applications 3-methoxypropane-1-sulfonyl fluoride (cas# 1227250-19-2) is a useful research chemical.<br></p>

<p>Applications 4-Methoxymethylcyclohexylmethanol is used in perfume compositions to give a stable fragrance like lily of the valley. It is also used as a reagent in the synthesis of 5-(cyclohexylmethylthio)-2-tert-butylpyridazin-3-ones and its analogs as acaricides and insecticides.<br>References Tanaka, S., et al. Jpn. Kokai Tokkyo Koho. JP 11035969 A 19990209. Feb 9, 1999; Bettarini, F., et al. Eur. Pat. Appl. EP 476573 A1 19920325. Mar 25, 1992<br></p>

<p>Applications 3-methyl-5-phenylisoxazole (cas# 1008-75-9) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-D-phenylalanine Methyl Ester Hydrochloride is one of the enatiomer in 4-Chloro-DL-phenylalanine Methyl Ester Hydrochloride (C377780) which is a tryptophan (T947200) hydroxylase (TPH) inhibitor and a serotonin (S274980) synthesis inhibitor. 4-Chloro-D-phenylalanine methyl ester hydrochloride is also known to induce memory deficits in rats.<br>References Aristieta, A., et al.: Psychopharmacology, No vol. given, 1 (2013); Bechtholt, A., et al.: Psychopharmacology, 190, 531 (2007); Jensen, J., et al.: Eur. Neuropsychopharm., 24, 148 (2014);<br></p>

<p>Applications Useful for the preparation of pseudopeptides as thrombolytic agents.<br>References Yabe, Y., et al.: J. Pharmacol. Exp. Ther., 289, 1176 (1999), Hines, I., et al.: Curr. Med. Chem., 10, 2661 (2003),<br></p>