Aminoácidos (AA)

Applications tert-Butyl 2-Bromo-2-methylpropanoate-D6 is an intermediate in the synthesis of Aztreonam-d6 (A965202), which is an isotope labeled Azetreonam (A965200), the first totally synthetic monocyclic β-lactam antibiotic.
References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),

Applications METHYL 2-METHYL-1-OXO-1,2,3,4-TETRAHYDRONAPHTHALENE-2-CARBOXYLATE (cas# 54125-61-0) is a useful research chemical.

Applications A 2-substituted 2’-Deoxyadenosine (D231620). Used in the synthesis of oligonucleotides.
References Ishikawa, F., et al.: J. Mol. Biol., 70, 475 (1972), Hattori, M., et al.: Biochemistry, 13, 2754 (1974), Kazimierczuk, Z., et al.: J. Med. Chem., 33, 1683 (1990),

Applications 3-Bromo-5-methylphenylboronic acid

Applications 4-Chloro-D-phenylalanine Methyl Ester Hydrochloride is one of the enatiomer in 4-Chloro-DL-phenylalanine Methyl Ester Hydrochloride (C377780) which is a tryptophan (T947200) hydroxylase (TPH) inhibitor and a serotonin (S274980) synthesis inhibitor. 4-Chloro-D-phenylalanine methyl ester hydrochloride is also known to induce memory deficits in rats.
References Aristieta, A., et al.: Psychopharmacology, No vol. given, 1 (2013); Bechtholt, A., et al.: Psychopharmacology, 190, 531 (2007); Jensen, J., et al.: Eur. Neuropsychopharm., 24, 148 (2014);

Applications 4-Methylpentanoic Acid-d12 (CAS# 116287-57-1) is a useful isotopically labeled research compound.

Applications 4-Iodo-2-methylbenzoic acid

Applications: L-Aspartic Acid Dibenzyl Ester p-Toluenesulfonate Salt is used in the preparation of Betulinic Acid derivatives that show inhibition towards HIV. It is also used in the preparation of piperidine functional amides which act as potent and highly selective human β3 agonists.
References Soler, F. J. Med. Chem., 39, 1069 (1999);

Applications 1-Methylpiperazine is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug.
References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);

Applications 3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-ylboronic acid, pinacol ester (cas# 1220696-32-1) is a useful research chemical.

Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.
References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);