Péptidos
Los péptidos son cadenas cortas de aminoácidos unidas por enlaces peptídicos, que desempeñan papeles importantes como moléculas biológicas en los procesos celulares. Funcionan como hormonas, neurotransmisores y moléculas de señalización, y se utilizan ampliamente en aplicaciones terapéuticas y diagnósticas. Los péptidos también son cruciales en la investigación para estudiar las interacciones de proteínas, actividades enzimáticas y vías de señalización celular. En CymitQuimica, ofrecemos una amplia selección de péptidos de alta calidad para apoyar sus necesidades de investigación y desarrollo en biotecnología y farmacéutica.
Subcategorías de "Péptidos"
Se han encontrado 29707 productos de "Péptidos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Hepcidin (baboon, cynomolgus, macaque, and gorilla)
This product is of Hepcidin Baboon, Cynomolgus, Macaque, and Gorilla origin contains the disulfide bonds: Cys7- Cys23, Cys10- Cys13, Cys11- Cys19, and Cys14- Cys22. Hepcidin is a hormone that is produced by the liver in response to iron overload and regulates iron uptake in the gastrointestinal tract. Hepcidin binds to ferroportin, the protein that transports iron across the enterocyte cell membrane, and mediates internalization of ferroportin. Interestingly Hepcidin also displays antimicrobial activity as it reduces the amount the iron available to pathogens invading the body.Fórmula:C113H170N36O31S9Pureza:Min. 95%Peso molecular:2,817.41 g/molHuman PD - L1 inhibitor V
PD-1 inhibitors and PD-L1 inhibitors are a group of checkpoint inhibitors being developed for the treatment of cancer.PD-1 and its ligand PD-L1 are critical in regulating T cell activation, tolerance and immunopathology. PD-1 is an immune checkpoint and guards against autoimmunity through two mechanisms. First, it promotes apoptosis of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells. Several types of cancer cells overexpress PD-L1 in order to escape from the PD-1/PD-L1 immunosurveillance mechanism. In this way, Human PD - L1 inhibitor V could be used in the treatment of cancers that overexpress PD-L1.Forma y color:PowderPeso molecular:1,484.8 g/molAc-VALDPIDISIVLNKIKSDLEESKEWIRRSNKILDSI-NH2
Peptide Ac-VALDPIDISIVLNKIKSDLEESKEWIRRSNKILDSI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.CONSENSUS B Tat - 17
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecular:1,619.8 g/molCRAMP-18
Cathelicidin-related anti-microbial peptide (CRAMP), is the mouse homologue of the human LL-37 antimicrobial peptide and shares 67% sequence identity with LL-37.CRAMP-18 is the anti-bacterial sequence derived from CRAMP, it possesses potent anti-bacterial activity against Gram-positive and Gram-negative bacterial strains with no haemolytic activity. As well as displaying direct anti-microbial activity, CRAMP-18 also binds to lipopolysaccharide (LPS) to neutralise LPS activity.CRAMP is a cationic peptide, encoded for by the Camp gene and is highly expressed in bone marrow. Its expression is up-regulated by infectious and inflammatory signals and it is secreted by cells such as neutrophils, epithelial cells, and macrophages.Peso molecular:2,147.61 g/molH-YGLVTYATYPK^-OH
Peptide H-YGLVTYATYPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.LCBiot-LRELHLNNN-NH2
Peptide LCBiot-LRELHLNNN-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-KKSRGDYMTMQIG-NH2
Peptide H-KKSRGDYMTMQIG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LLIVYPWTQR^-OH
Peptide H-LLIVYPWTQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-A^QCY-OH
Peptide H-A^QCY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-LLLEYLEEK^-OH
Peptide H-LLLEYLEEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
C-terminal Sortagging-[Cys(Sulfocyanine7)]
This C-terminal Sortagging peptide acts as a (oligo)glycine nucleophile in the final steps of a sortagging protein labelling reaction. This reaction results in the (Sulfocyanine7) fluorescent moiety being attached to the C-terminus of the target protein or peptide.A substrate peptide containing the LPXTG motif is recognised and cleaved by the enzyme Sortase A (SrtA) from Staphylococcus aureus. The catalytic cysteine residue in the active site of SrtA, serves as a nucleophile to cleave the peptide bond between threonine and glycine of the substrate peptide. Cleavage results in the formation of a thioacyl intermediate between the substrate peptide and SrtA. This intermediate is then resolved by the N-terminus of this (oligo)glycine nucleophile peptide, resulting in the creation of a new peptide bond that links the substrate peptide to this peptide and its fluorescent dye. This method of protein labelling is known as sortagging.This peptide contains Sulfocyanine7, which is a NIR (near infrared) emitting fluorescent dye.Peso molecular:1,121.4 g/molGlepaglutide
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Fórmula:C197H325N53O55Peso molecular:4,316.01 g/molEGFR/kinKDR peptide substrate
Substrate of the epidermal growth factor receptor (EGFR), a member of the receptor tyrosine kinase family known as ErbBs or HER receptors. These receptors are involved in the regulation of cell proliferation, survival, differentiation and migration. However their dysregulation can contribute towards many diseases such as cancer.Binding to the ligand binding domain of the EGFR causes receptor dimerization. This is sequentially followed by the tyrosine kinase domain being activated and the tyrosines on the C-terminal tail become phosphorylated, which in turn activates downstream signalling pathways.
Forma y color:PowderPeso molecular:1,620.9 g/molH-SVDQRGNQ-NH2
Peptide H-SVDQRGNQ-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-FAM]-M918
Novel cell-penetrating peptide (CPP). M918 was derived from the tumour suppressor protein p14ARF and can be utilized for both covalent and non-covalent delivery of macromolecules in animal and plant cells. CPPs are able to cross the cell membrane at low micromolar concentrations without causing significant membrane damage in vivo and in vitro.This cationic CPP Peptide is labelled with an N-terminal 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecular:3,009.34 g/molTAT 2-4
TAT 2-4 is derived from human immunodeficiency virus (HIV) transactivator of transcription (TAT) residues 47-58. TAT (47-58) is a cell penetrating cationic peptide derived from the N-terminus of the Tat protein, which is a trans-activator of the transcription protein present in the human immunodeficiency virus (HIV). As a cell penetrating peptide (CPP) TAT aids in the cellular uptake of molecules and hence serves a valuable purpose in transduction methods. TAT 2-4 are residues (47-58) of HIV TAT protein repeated back to back, this dimer of TAT sequences has been shown to be the most efficient oligomer for cell penetration. This TAT dimer has been used in previous studies to deliver a wide variety of cargoes including fluorophores, chelators and DNA to target cells.Forma y color:PowderPeso molecular:3,213.9 g/molIA-2 797-805 (HLA-A*02:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
H-Trp(Boc)-2-ClTrt-Resin (100-200 mesh) 1% DVB
H-Trp(Boc)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for the synthesis of peptides. It is used as building blocks in the synthesis of peptide derivatives, such as amines, alcohols, thiols, and other amino acids. This resin has been shown to be stable in aqueous or organic solvents.
Pureza:Min. 95%KRREILSRRPSYR-acid
Protein kinases are important drug targets for numerous diseases to try and better evaluate the enzyme specificity, affinity, mode of action and identify possible inhibitors. In vitro assays and synthetic substrates provide valuable data about human kinase activity. CREBtide KRREILSRRPSYR is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein) it is a substrate for protein kinase A (PKA)(Km = 3.9 mM). However, it has also been tested as a substrate for other protein kinases, including cAMP-dependent protein kinase (cAK) and protein kinase C (PKC). Immunoblots and autoradiography have been used for CREBtide KRREILSRRPSYR in vitro kinase analysis.Forma y color:PowderPeso molecular:1,716 g/molH-DLLDTASALYR^-OH
Peptide H-DLLDTASALYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.OVA peptides pool
Overlaping peptide library of ovalbumin, 15 amino acids per peptide with offset 11. Purity crude. All peptides are pooled in a single tube.
N-formylated PSMalpha3
Pathogenic Staphylococcus aureus strains produce N-formylmethionyl containing peptides. Peptides starting with an N-formylated methionyl group constitute a unique hallmark of bacterial as well as mitochondrial metabolism, and professional phagocytes of our innate immune system recognise this microbial/mitochondrial pattern as a danger signal that guides innate immune cells.All PSMα peptides have the same basic functions and promote virulence through effects on discrete neutrophil functions (i.e. chemotaxis) and by being cytotoxic at higher concentrations. PSMα2 and PSMα3 can both bind to FPR2 and trigger superoxide release in neutrophils at low nanomolar concentrations. In addition, at high nanomolar concentrations they display cytotoxicity selectively on apoptotic neutrophil membranes and this occurs in an FPR2 independent manner.Forma y color:PowderPeso molecular:2,633.4 g/molSRC-1 (676-700)
Steroid Receptor Coactivator - 1 (676-700).
Forma y color:PowderPeso molecular:2,797.4 g/molH-L^APITSDPTEATAVGAVEASFK-OH
Peptide H-L^APITSDPTEATAVGAVEASFK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ELLESYIDGR^-OH
Peptide H-ELLESYIDGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Angiotensin II (1-8)
Angiotensin II (Ang-II) is a key signalling peptide of the renin angiotensin system (RAS) which is involved in regulating blood pressure, cardiovascular function and energy balance. RAS activity is elevated in obesity and is widely studied in relation to lifestyle-related diseases.Ang-II is produced from angiotensinogen (AGT) via the intermediate angiotensin I (Ang-I). AGT is cleaved by the aspartyl-protease, renin, to produce Ang-I, which is then cleaved by the dicarboxyl-peptidase angiotensin converting enzyme (ACE). ACE removes a histidine and a leucine from the C-terminus of Ang-I to form Ang-II.Ang-II exerts its affect by binding to the G-protein-coupled receptors- Ang II type 1 (AT1) and Ang II type 2 (AT2) receptors. Ang-II plays central roles in glucose metabolism and blood pressure. Increased levels of Ang-II have also been associated with Alzheimer's disease, and certain cancers including oesophageal squamous cell carcinoma (ESCC), brain cancers and breast cancers. The effects of Ang-II appear to be supressed by another branch of the RAS- the ACE2/Ang-(1-7)/Mas pathway.Peso molecular:1,045.5 g/molUBA3 (59-72) peptide
Peptide derived from the ubiquitin-activating enzyme 3 (UBA3), the catalytic subunit of the NEDD8-activating enzyme (NAE).Forma y color:PowderPeso molecular:1,495.8 g/molYSA acid
YSA binds to the extracellular domain of ephrin type-A receptor 2 (EphA2) with high affinity and selectivity. YSA binding activates EphA2 and its tumour suppressing downstream signalling pathways (including inhibition of the PI3K/Akt and ERK pathways), and promotes receptor internalisation.EphA2 is highly expressed in many types of solid tumour, and the level of EphA2 expression is positively correlated with malignancy and poor prognosis in some cancer types.YSA has been shown to be an effective targeting peptide of chemotherapeutic drugs to EphA2 expressing tumours. YSA-drug conjugates are able to selectively target EphA2 expressing tumours, both activating tumour supressing downstream signalling pathways, and becoming effectively internalised by cancer cells to further increase the potency of the chemotherapeutic drug. YSA-drug conjugates have been shown to be dramatically more effective at inhibiting tumour growth than chemotherapy alone. Selective tumour targeting with YSA could also reduce the systemic toxicity caused by nonselective and highly toxic chemotherapy agents, and thus reduce adverse side effects of chemotherapy.Peso molecular:1,346.6 g/molAc-LRGGAPTK-NH2
Peptide Ac-LRGGAPTK-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.MBP Ac1-9 (4Y)
This peptide constitutes the acetylated N-terminal region of murine myelin basic protein (MBP) and displays high affinity for major histocompatibility complexes (MHC). This high MHC affinity is due to substitution of the native lysine at position 4 for a tyrosine. Substitution increases the MHC binding affinity of the peptide by around 1 million fold, therefore creating a superagonist ligand. MBP is an integral component of myelin found in the central nervous system (CNS) vital for the development and stability of the myelin sheath where it plays a role in membrane adhesion. MBP may be targeted by auto-antibodies in diseases such as multiple sclerosis. The low affinity of the native lysine containing MBP 1-9 peptide for MCH class II may result in MBP auto-reactive T cells escaping central-tolerance where self reactive T cells are usually eliminated. MBPs constitute an extraordinarily varied collection of splice isoforms which show a myriad of post-translational modifications.
Forma y color:PowderPeso molecular:1,133.22 g/molInsulin A Chain (A12-21)
Type I diabetes is an autoimmune condition caused by the destruction of insulin-producing β cells. The initiation mechanism is unclear but involves activating autoreactive T cells against the β-cell-specific antigen, insulin.RIP-B7.1 mice express CD80 on pancreatic β cells and are a model for studying de novo induction of diabetogenic CD8 T cells. Immunization of RIP-B7.1 mice with preproinsulin (ppins)-encoding plasmid DNA induces experimental autoimmune diabetes (EAD). EAD is associated with significant induction of CD8 T cells specific for the (A12-21) restricted epitope leading to the destruction of β cells.The Insulin A Chain (A12-21) epitope is recognised by pancreas-infiltrating CD8 T cells isolated from immunized, diabetic RIP-B7.1 mice as shown by flow cytometry. The Insulin A Chain (A12-21) epitope can also be used to stimulate inducible IFN- expression of ppins-primed CD8 T cells ex vivo as determined by flow cytometry. GFP fusion has shown the expression of insulin A chain (A12-21) epitope in HeLa cells.Peso molecular:1,246.3 g/molH-NTAYLQMNSL^R-OH
Peptide H-NTAYLQMNSL^R-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Ac-CKIQEFHVDGKE-NH2
Peptide Ac-CKIQEFHVDGKE-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Tetanus Toxin P2 (830 - 844)
Tetanus Toxin P2 (830 - 844) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani. The neurotoxins produced by Clostridium tetani are among the most potent molecules known to humankind. Once in the body, the toxin binds to the basal lamina at the neuromuscular junction. From here, the toxin is transported to inhibitory interneurons in the spinal cord, where it prevents the release of neurotransmitters, which causes spastic paralysis.The P2 protein has antigenic properties that are reflective of the neurotoxin released by Clostridium tetani. Therefore, P2 is a suitable epitopes for CD4+ T cells and can be used to stimulate the release of IFNg, which is a cytokine that promotes macrophage activity and coordinates lymphocyte endothelium interactions.
Forma y color:PowderPeso molecular:1,724 g/molH-EDLTEIR^-OH
Peptide H-EDLTEIR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VIEHIMEDLDTNADK^-OH
Peptide H-VIEHIMEDLDTNADK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
IFNB1 (118-132) Human
Recombinant human interferon-β (IFNB) is a therapeutic for certain stages of multiple sclerosis (MS). However, a significant portion of patients develop neutralising antibodies within 2 years and prevent clinical efficacy of the treatment, this was correlated to a specific rise in IgG. Sequencing of IFNB1 revealed a CD4+ T cell epitope residues (118-132) that contains critical T cell activation residues. The identification of this sequences can now allow it to be manipulated to hopefully provide new interferon treatments that reduces the capacity for induction of neutralising antibodies in MS patients. The IFNB1 (118-132) epitope can be used for immunological investigations such as T cell activation, antibody recognition via immunoassays and immunohistochemistry. This may provide further insights into certain haplotypes correlating to IFNB responses in MS treatment.Peso molecular:1,906.23 g/molAc-RLR-[AMC] Proteasome Substrate
Fluorogenic substrate peptide to assay trypsin-like activity. In its intact state this peptide is non-fluorescent, however when aminomethylcoumarin (AMC) is released upon hydrolysation, fluorescence can be detected. This peptide is therefore a useful tool for analysing trypsin-like enzyme activity.AMC is a fluorescent dye with excitation maxima at around 360 nm and emission maxima at around 450 nm. AMC can be excited with a mercury lamp and observed using a UV filter set.Peso molecular:642.4 g/molCMVpp65 - 101 (TSGSDSDEELVTTER)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecular:1,625.6 g/molHPV 16 E2 69-77 (HLA-A*02:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Biotin-PEG2-Claudin-9
Biotin-PEG2-Claudin-9 is derived from the tight junction protein Claudin-9 which is encoded by the CLDN6 gene and can be found within epithelial cell to cell contacts. Structurally, the Claudin family, of which Claudin-9 is a member, are transmembrane proteins containing two extracellular loops and are involved in maintaining cell polarity and controlling paracellular ion flux.Reduction in the number of Claudins has been associated with tumour formation. This may be due to Claudin role in maintaining cell detachment and migration.Claudin-9 has been shown to be overexpressed in hepatocellular carcinoma (HCC) and has the ability to increase the metastasis of hepatocytes. It further influences the activation of the Stat3 signalling pathway through tyrosine kinase 2. Overall CLDN9 demonstrates itself to be a HCC proto-oncogene.This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains a polyethylene glycol spacer (PEG2).Forma y color:PowderPeso molecular:2,881.5 g/molACTH (7-38) Human
Segment 7-38 of adrenocorticotropic hormone (ACTH). ACTH, also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex.Peso molecular:3,659.11 g/molPantinin-2
Pantinin-2, like other pantinin peptides, has high activity against Gram-positive bacteria yet weak activity against Gram-negative bacteria. Pantinin-2 also displays activity against Candida tropicalis and has relatively mild haemolytic activity against human red blood cells.Forma y color:PowderPeso molecular:1,403.8 g/molH-DQGGELLSLR^-OH
Peptide H-DQGGELLSLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Hp1404
Antimicrobial peptides (AMP) are proving a lucrative area for antibiotics in the era of bacterial resistance. Of note, the scorpion Heterometrus petersii was found to produce Hp1404, an amphipathic cationic peptide with specific activity against Gram-positive bacteria- Hp1404 was shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA). The mode of action is by membrane penetration and disruption. MRSA did not gain resistance after several exposures to Hp1404 suggesting it may be a key agent against the rise of antibiotic resistance. Importantly, bacterial lethality was maintained with low toxicity to mammalian cells. Hp1404 is being used to generate analogues with reduced toxicity to mammalian cells and improved antimicrobial potency against a wider range of organisms.Forma y color:PowderPeso molecular:1,544.9 g/molInfluenza Virus Nucleoprotein (311 - 325)
The Influenza Virus Nucleoprotein (311 - 325) is a component of the viral ribonucleotide complex, derived from the influenza virus and it is involved in viral replication, RNA packing and nuclear trafficking. As a monomer it contains basic residues which allow it to bind to single stranded RNA and through its flexible tail loop it has the ability to form NP oligomers.Furthermore NP is able to support the viral polymerase structurally, through associating with the two subunits PB1 and PB2, and it allows the viral ribonucleotide complex to be transported in and out of the nucleus due to its nuclear localisation and nuclear export signals.During influenza viral replication messenger RNA, viral genome RNA and complementary positive-sense RNA are produced and NP is crucial for this replication.Inhibitors of NP have potential to be used to prevent the influenza virus in humans.Peso molecular:1,764.9 g/mol
![C-terminal Sortagging-[Cys(Sulfocyanine7)]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1101496.webp&w=3840&q=75)
![[5-FAM]-M918](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1100287.webp&w=3840&q=75)
![Ac-RLR-[AMC] Proteasome Substrate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FCRB1100438.webp&w=3840&q=75)
